Published in Biochem Pharmacol on August 01, 1979
Modulation of cyclic AMP metabolism by S-adenosylhomocysteine and S-3-deazaadenosylhomocysteine in mouse lymphocytes. Proc Natl Acad Sci U S A (1980) 0.91
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev (1999) 6.93
Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell (1998) 5.92
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes Dev (1998) 3.92
Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure. Cell (2001) 3.80
Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain. J Exp Med (1997) 2.91
Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science (1996) 2.56
Plasmin induces local thrombolysis without causing hemorrhage: a comparison with tissue plasminogen activator in the rabbit. Thromb Haemost (2001) 1.98
Adenosine inhibition of lymphocyte-mediated cytolysis: possible role of cyclic adenosine monophosphate. Science (1975) 1.92
Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo. Immunity (1997) 1.70
Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells. J Exp Med (2000) 1.57
TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses. Immunity (1999) 1.56
Mouse virulence of K(L) antigen-containing strains of Escherichia coli. J Bacteriol (1969) 1.52
Brca1 required for T cell lineage development but not TCR loci rearrangement. Nat Immunol (2000) 1.48
Metabolism of 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide and related five-membered heterocycles to 5'-triphosphates in human blood and L5178Y cells. Biochem Pharmacol (1978) 1.36
Inhibition of lymphocyte-mediated cytolysis by 3-deazaadenosine: evidence for a methylation reaction essential to cytolysis. Proc Natl Acad Sci U S A (1978) 1.35
3'-azido-3'-deoxythymidine. An unusual nucleoside analogue that permeates the membrane of human erythrocytes and lymphocytes by nonfacilitated diffusion. J Biol Chem (1987) 1.32
Adenine as substrate for purine nucleoside phosphorylase. Can J Biochem (1971) 1.22
In vivo evidence that caspase-3 is required for Fas-mediated apoptosis of hepatocytes. J Immunol (1999) 1.14
Purine nucleobase transport in human erythrocytes. Reinvestigation with a novel "inhibitor-stop" assay. J Biol Chem (1988) 1.09
A conformational study of yeast phenylalanine transfer ribonucleic acid. J Biol Chem (1971) 1.08
Thrombolytic potency of acid-stabilized plasmin: superiority over tissue-type plasminogen activator in an in vitro model of catheter-assisted thrombolysis. J Thromb Haemost (2003) 1.03
Transport and metabolism of 9-beta-D-arabinofuranosylguanine in a human T-lymphoblastoid cell line: nitrobenzylthioinosine-sensitive and -insensitive influx. Cancer Res (1990) 1.02
2-Fluoroadenosine 3':5'-monophosphate. A metabolite of 2-fluoroadenosine in mouse cytotoxic lymphocytes. J Biol Chem (1976) 0.99
Chemotactic peptide induces cAMP elevation in human neutrophils by amplification of the adenylate cyclase response to endogenously produced adenosine. J Biol Chem (1989) 0.96
3-Deazaadenosine-induced disorganization of macrophage microfilaments. Proc Natl Acad Sci U S A (1985) 0.94
Reversible inhibition of lymphocyte mediated cytolysis by dimethyl sulfoxide (DMSO). J Immunol (1973) 0.93
Acyclovir transport into human erythrocytes. J Biol Chem (1988) 0.92
Inhibition of lymphocyte-mediated cytolysis by adenosine analogs. Biochemical studies concerning mechanism of action. Biochem Pharmacol (1978) 0.92
Modulation of cyclic AMP metabolism by S-adenosylhomocysteine and S-3-deazaadenosylhomocysteine in mouse lymphocytes. Proc Natl Acad Sci U S A (1980) 0.91
Serum corticosterone, interleukin-1 and tumour necrosis factor in rat experimental endotoxaemia: comparison between Lewis and Wistar strains. Br J Pharmacol (1993) 0.89
Passive hemagglutination. II. Titration of antibody against determinants unique for aggregated denatured bovine serum albumin and further studies on gelatin. J Immunol (1970) 0.89
Studies on passive hemagglutination. I. Titration of "early" and "late" antibodies with tanned red cells sensitized with native or denatured bovine serum albumin. J Immunol (1969) 0.89
Antibody to Corynebacterium parvum in normal human and animal sera. Infect Immun (1977) 0.89
Imaging inflammation with 99Tcm-labeled chemotactic peptides: analogues with reduced neutropenia. Nucl Med Commun (1996) 0.88
iNOS expression and nitrotyrosine formation in the myocardium in response to inflammation is controlled by the interferon regulatory transcription factor 1. Circulation (1997) 0.86
Membrane permeation mechanisms of 2',3'-dideoxynucleosides. Biochem Pharmacol (1993) 0.84
Enantiomeric selectivity of carbovir transport. J Biol Chem (1992) 0.84
An assay for inhibitors of nucleoside transport based upon the use of 5-[125I]iodo-2'-deoxyuridine as permeant. Anal Biochem (1986) 0.84
A modified procedure for large-scale preparation of beef liver tRNA. Anal Biochem (1970) 0.84
Antagonism by taxol of effects of microtubule-disrupting agents on lymphocyte cAMP metabolism and cell function. Proc Natl Acad Sci U S A (1984) 0.83
3-deazaadenosine inhibits leukocyte adhesion and ICAM-1 biosynthesis in tumor necrosis factor-stimulated human endothelial cells. J Immunol (1990) 0.82
Development of specific antibody and in vivo response to antigen in different rat strains: effect of dexamethasone and importance of endogenous corticosteroids. Agents Actions (1993) 0.82
Transport of 5-fluorouracil and uracil into human erythrocytes. Biochem Pharmacol (1993) 0.82
ATP depletion in human platelets caused by permeabilization with saponin does not prevent serotonin secretion induced by collagen. Biochem Biophys Res Commun (1985) 0.82
Ganciclovir permeation of the human erythrocyte membrane. Biochem Pharmacol (1991) 0.82
Imidazo[4,5-c]pyridines (3-deazapurines) and their nucleosides as immunosuppressive and antiinflammatory agents. J Med Chem (1986) 0.82
Separation of 6-thiopurine derivatives on DEAE-sephadex columns and in the high-pressure liquid chromatograph. J Chromatogr (1973) 0.82
Effects of calmodulin antagonists on immune mouse lymphocytes. Mol Pharmacol (1984) 0.81
In vivo and in vitro antitumor activity expressed by cells of concomitantly immune mice. Cancer Res (1983) 0.80
Metabolism of tubercidin and formycin to their 3':5'-cyclic nucleotides in mammalian cells. J Biol Chem (1978) 0.80
3-Deazaadenosine 5'-triphosphate: a novel metabolite of 3-deazaadenosine in mouse leukocytes. Biochem Pharmacol (1989) 0.80
Iron chelates bind nitric oxide and decrease mortality in an experimental model of septic shock. Proc Natl Acad Sci U S A (1996) 0.80
Regulation of guanosine triphosphate cyclohydrolase and tetrahydrobiopterin levels and the role of the cofactor in tyrosine hydroxylation in primary cultures of adrenomedullary chromaffin cells. J Neurochem (1986) 0.80
Xenogeneic ICAM-1 gene transfer suppresses tumorigenicity and generates protective antitumor immunity. Gene Ther (1996) 0.79
Ca2+ ionophore-induced cyclic adenosine-3',5'-monophosphate elevation in human neutrophils. A calmodulin-dependent potentiation of adenylate cyclase response to endogenously produced adenosine: comparison to chemotactic agents. Biochem Pharmacol (1991) 0.79
Effects of adenosine on neutrophil polarization induced by N-formyl-methionyl-leucyl-phenylalanine, sodium propionate and colchicine. Agents Actions (1989) 0.79
Endogenous corticosteroids modulate lymphoproliferation and susceptibility to experimental allergic encephalomyelitis in the Brown Norway rat. Int Arch Allergy Immunol (1995) 0.78
Inhibition of lymphocyte-mediated cytolysis by 2-fluoroadenosine--evidence for two discrete mechanisms of drug action. Biochem Pharmacol (1978) 0.78
Inhibition of lymphocyte-mediated cytolysis and cyclic AMP phosphodiesterase by erythro-9-(2-hydroxy-3-nonyl)adenine. J Immunopharmacol (1982) 0.78
2',3'-Dideoxythymidine permeation of the human erythrocyte membrane by nonfacilitated diffusion. Biochem Biophys Res Commun (1988) 0.78
Immune reaction of tumor-bearing mice to Propionibacterium acnes and the antitumor effect of the bacteria. Cancer Immunol Immunother (1982) 0.78
Immunosuppressive effects of the S-adenosylhomocysteine hydrolase inhibitor, 3-deazaadenosine. J Immunopharmacol (1982) 0.78
Formation of 5'-nucleotides of 6-methylmercaptopurine ribonucleoside in human tissues in vitro. Biochem Pharmacol (1974) 0.78
Effect of assay conditions on the magnesium requirement of the transfer reaction catalyzed by phenylalanyl-tRNA synthetase from bakers' yeast. Biochem Biophys Res Commun (1972) 0.77
Metabolic formation of nucleoside-modified analogues of S-adenosylmethionine. Biochem Biophys Res Commun (1979) 0.77
Membrane permeation characteristics of 5'-modified thymidine analogs. Mol Pharmacol (1992) 0.77
Inhibition of cyclic AMP phosphodiesterase by 5'-deoxy-5'-S-isobutylthioadenosine at biologically active concentrations of drug. Life Sci (1981) 0.77
Taxol inhibits N-formyl-methionyl-leucyl-phenylalanine (FMLP)-induced human neutrophil polarization and H2O2 production while decreasing [3H]FMLP binding. Agents Actions (1987) 0.77
3-Deazaadenosine. S-adenosylhomocysteine hydrolase-independent mechanism of action in mouse lymphocytes. J Biol Chem (1984) 0.77
Nucleoside 3',5'-cyclic monophosphate metabolites of purine analogs. Possible role as physiological mediators. Biochem Pharmacol (1979) 0.77