Suppression of nuclear factor-κB activation and inflammation in microglia by physically modified saline.

PubWeight™: 1.06‹?› | Rank: Top 15%

🔗 View Article (PMC 3436140)

Published in J Biol Chem on June 29, 2012

Authors

Saurabh Khasnavis1, Arundhati Jana, Avik Roy, Monalisa Mazumder, Bharat Bhushan, Tony Wood, Supurna Ghosh, Richard Watson, Kalipada Pahan

Author Affiliations

1: Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.

Articles citing this

Cinnamon treatment upregulates neuroprotective proteins Parkin and DJ-1 and protects dopaminergic neurons in a mouse model of Parkinson's disease. J Neuroimmune Pharmacol (2014) 1.57

Protection of Tregs, suppression of Th1 and Th17 cells, and amelioration of experimental allergic encephalomyelitis by a physically-modified saline. PLoS One (2012) 0.97

Gemfibrozil and fenofibrate, Food and Drug Administration-approved lipid-lowering drugs, up-regulate tripeptidyl-peptidase 1 in brain cells via peroxisome proliferator-activated receptor α: implications for late infantile Batten disease therapy. J Biol Chem (2012) 0.89

Activation of peroxisome proliferator-activated receptor α induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders. J Biol Chem (2015) 0.86

A physically-modified saline suppresses neuronal apoptosis, attenuates tau phosphorylation and protects memory in an animal model of Alzheimer's disease. PLoS One (2014) 0.85

Up-regulation of ciliary neurotrophic factor in astrocytes by aspirin: implications for remyelination in multiple sclerosis. J Biol Chem (2013) 0.84

6-Shogaol, an active compound of ginger, protects dopaminergic neurons in Parkinson's disease models via anti-neuroinflammation. Acta Pharmacol Sin (2013) 0.82

Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Ciliary Neurotrophic Factor in Astrocytes and Oligodendrocytes. Neurochem Res (2015) 0.78

Enhancement of morphological plasticity in hippocampal neurons by a physically modified saline via phosphatidylinositol-3 kinase. PLoS One (2014) 0.78

RNS60, a charge-stabilized nanostructure saline alters Xenopus Laevis oocyte biophysical membrane properties by enhancing mitochondrial ATP production. Physiol Rep (2015) 0.77

Apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers is lower in water enriched in oxygen by electrolysis than injection. Drug Des Devel Ther (2015) 0.77

HSP60 mediates the neuroprotective effects of curcumin by suppressing microglial activation. Exp Ther Med (2016) 0.75

Cytokine pathway disruption in a mouse model of schizophrenia induced by Munc18-1a overexpression in the brain. J Neuroinflammation (2014) 0.75

AKT and its related molecular feature in aged mice skin. PLoS One (2017) 0.75

Cinnamon Converts Poor Learning Mice to Good Learners: Implications for Memory Improvement. J Neuroimmune Pharmacol (2016) 0.75

Microglia activation triggers oligodendrocyte precursor cells apoptosis via HSP60. Mol Med Rep (2017) 0.75

Immune Modulation in the Treatment of Amyotrophic Lateral Sclerosis: A Review of Clinical Trials. Front Neurol (2017) 0.75

Articles cited by this

Shared principles in NF-kappaB signaling. Cell (2008) 20.96

I kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science (1988) 16.40

Parkinson's disease: mechanisms and models. Neuron (2003) 14.84

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J Biol Chem (1994) 6.91

The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer . J Med Chem (2008) 4.49

Characterization of ameboid microglia isolated from developing mammalian brain. J Neurosci (1986) 4.36

PI 3-kinase p110beta: a new target for antithrombotic therapy. Nat Med (2005) 3.96

Microglia as mediators of inflammatory and degenerative diseases. Annu Rev Neurosci (1999) 3.90

Targeting phosphoinositide 3-kinase: moving towards therapy. Biochim Biophys Acta (2007) 3.69

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells. Proc Natl Acad Sci U S A (1994) 3.37

Multifunctional nanoparticles for combining ultrasonic tumor imaging and targeted chemotherapy. J Natl Cancer Inst (2007) 2.77

Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B. Mol Cell Biol (1995) 2.69

Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. J Clin Invest (1997) 2.44

Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A (2007) 2.43

Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J Neurosci (2006) 1.90

Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging. Part Fibre Toxicol (2010) 1.89

Novel anti-inflammatory therapy for Parkinson's disease. Trends Pharmacol Sci (2003) 1.87

Changes in cytokines and neurotrophins in Parkinson's disease. J Neural Transm Suppl (2000) 1.83

Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo. J Neurochem (2000) 1.78

Up-regulation of BDNF in astrocytes by TNF-alpha: a case for the neuroprotective role of cytokine. J Neuroimmune Pharmacol (2006) 1.77

Microglia as liaisons between the immune and central nervous systems: functional implications for multiple sclerosis. Glia (2002) 1.74

Ligation of CD40 stimulates the induction of nitric-oxide synthase in microglial cells. J Biol Chem (2001) 1.71

Up-regulation of microglial CD11b expression by nitric oxide. J Biol Chem (2006) 1.64

Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model. FASEB J (2006) 1.63

Retracted IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation. J Biol Chem (2011) 1.47

Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes. J Biol Chem (1996) 1.46

p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma. Curr Biol (2005) 1.43

Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease. J Neurosci (2010) 1.38

Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes. Free Radic Biol Med (2005) 1.36

Involvement of phosphatidylinositol 3-kinase-mediated up-regulation of I kappa B alpha in anti-inflammatory effect of gemfibrozil in microglia. J Immunol (2007) 1.35

Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses. J Immunol (2009) 1.32

MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65. J Immunol (2007) 1.31

Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease. J Neurosci (2009) 1.27

Beta-amyloid-induced inflammation and cholinergic hypofunction in the rat brain in vivo: involvement of the p38MAPK pathway. Neurobiol Dis (2002) 1.25

Cytokine induction of NO synthase II in human DLD-1 cells: roles of the JAK-STAT, AP-1 and NF-kappaB-signaling pathways. Br J Pharmacol (1998) 1.13

Increased cerebrospinal fluid concentration of nitrite in Parkinson's disease. Neuroreport (1995) 1.11

Signals for the induction of nitric oxide synthase in astrocytes. Neurochem Int (2006) 1.04

Modeling neuroinflammatory pathogenesis of Parkinson's disease. Prog Brain Res (2010) 1.02

Amyloid beta peptide-induced corpus callosum damage and glial activation in vivo. Neuroreport (2003) 1.00

Testing NF-κB-based therapy in hemiparkinsonian monkeys. J Neuroimmune Pharmacol (2012) 0.98

Diffusive shielding stabilizes bulk nanobubble clusters. Chemphyschem (2012) 0.83

Do stable nanobubbles exist in mixtures of organic solvents and water? J Phys Chem B (2010) 0.77

Articles by these authors

Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A (2007) 2.43

Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J Neurosci (2006) 1.90

Engagement of collagen-binding integrins promotes matrix metalloproteinase-9-dependent E-cadherin ectodomain shedding in ovarian carcinoma cells. Cancer Res (2007) 1.90

Antineuroinflammatory effect of NF-kappaB essential modifier-binding domain peptides in the adoptive transfer model of experimental allergic encephalomyelitis. J Immunol (2004) 1.84

Up-regulation of BDNF in astrocytes by TNF-alpha: a case for the neuroprotective role of cytokine. J Neuroimmune Pharmacol (2006) 1.77

Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia. J Biol Chem (2002) 1.73

Shark-skin surfaces for fluid-drag reduction in turbulent flow: a review. Philos Trans A Math Phys Eng Sci (2010) 1.69

Up-regulation of microglial CD11b expression by nitric oxide. J Biol Chem (2006) 1.64

Cinnamon treatment upregulates neuroprotective proteins Parkin and DJ-1 and protects dopaminergic neurons in a mouse model of Parkinson's disease. J Neuroimmune Pharmacol (2014) 1.57

Novel small-molecule inhibitors of RNA polymerase III. Eukaryot Cell (2003) 1.56

Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease. J Biol Chem (2004) 1.55

Regulation of inducible nitric oxide synthase gene in glial cells. Antioxid Redox Signal (2006) 1.50

Fibrillar amyloid-beta peptides activate microglia via TLR2: implications for Alzheimer's disease. J Immunol (2008) 1.47

Induction of tumor necrosis factor-alpha (TNF-alpha) by interleukin-12 p40 monomer and homodimer in microglia and macrophages. J Neurochem (2003) 1.44

Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease. J Neurosci (2010) 1.38

Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase. J Neurosci (2004) 1.38

Prostate HDR radiation therapy: a comparative study evaluating the effectiveness of pain management with peripheral PCA vs. PCEA. Urol Nurs (2006) 1.37

Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes. Free Radic Biol Med (2005) 1.36

Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha. Mol Pharmacol (2007) 1.35

Role of very-late antigen-4 (VLA-4) in myelin basic protein-primed T cell contact-induced expression of proinflammatory cytokines in microglial cells. J Biol Chem (2003) 1.35

Involvement of phosphatidylinositol 3-kinase-mediated up-regulation of I kappa B alpha in anti-inflammatory effect of gemfibrozil in microglia. J Immunol (2007) 1.35

Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses. J Immunol (2009) 1.32

MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65. J Immunol (2007) 1.31

Tumor necrosis factor-alpha at the crossroads of neuronal life and death during HIV-associated dementia. J Neurochem (2003) 1.31

Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease. J Neurosci (2009) 1.27

Ceramide and neurodegeneration: susceptibility of neurons and oligodendrocytes to cell damage and death. J Neurol Sci (2009) 1.26

Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitis. J Immunol (2007) 1.26

Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes. Free Radic Biol Med (2005) 1.22

Sodium phenylacetate inhibits adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice at multiple steps. J Immunol (2003) 1.20

A simplified method for isolating highly purified neurons, oligodendrocytes, astrocytes, and microglia from the same human fetal brain tissue. Neurochem Res (2007) 1.20

Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α. Cell Rep (2013) 1.19

High nuclear S100A6 (Calcyclin) is significantly associated with poor survival in pancreatic cancer patients. Cancer Res (2005) 1.18

Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons. J Neuroimmune Pharmacol (2011) 1.17

Myelin basic protein-primed T cells induce nitric oxide synthase in microglial cells. Implications for multiple sclerosis. J Biol Chem (2002) 1.16

Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases. Free Radic Biol Med (2008) 1.16

Knowledge of, attitude towards, and prevalence of tobacco use among dental students in Himachal Pradesh State, India. Oral Health Dent Manag (2013) 1.15

Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease. PLoS One (2012) 1.13

TNF-alpha preconditioning protects neurons via neuron-specific up-regulation of CREB-binding protein. J Immunol (2009) 1.12

Differential regulation of Mn-superoxide dismutase in neurons and astroglia by HIV-1 gp120: Implications for HIV-associated dementia. Free Radic Biol Med (2007) 1.08

Oxidative stress kills human primary oligodendrocytes via neutral sphingomyelinase: implications for multiple sclerosis. J Neuroimmune Pharmacol (2007) 1.08

Prospects of statins in Parkinson disease. Neuroscientist (2011) 1.07

Shark skin inspired low-drag microstructured surfaces in closed channel flow. J Colloid Interface Sci (2012) 1.07

Role of protein kinase R in double-stranded RNA-induced expression of nitric oxide synthase in human astroglia. FEBS Lett (2004) 1.07

IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages. Mol Immunol (2008) 1.07

Polypyrimidine tract-binding protein (PTB) differentially affects malignancy in a cell line-dependent manner. J Biol Chem (2008) 1.07

Biomimetic structures for fluid drag reduction in laminar and turbulent flows. J Phys Condens Matter (2009) 1.06

Hierarchical roughness optimization for biomimetic superhydrophobic surfaces. Ultramicroscopy (2007) 1.05

Dynamic effects of bouncing water droplets on superhydrophobic surfaces. Langmuir (2008) 1.05

Signals for the induction of nitric oxide synthase in astrocytes. Neurochem Int (2006) 1.04

Biofouling: lessons from nature. Philos Trans A Math Phys Eng Sci (2012) 1.04

Gemfibrozil, stretching arms beyond lipid lowering. Immunopharmacol Immunotoxicol (2009) 1.03

Biomimetic superhydrophobic surfaces: multiscale approach. Nano Lett (2007) 1.03

Proteinase suppression by E-cadherin-mediated cell-cell attachment in premalignant oral keratinocytes. J Biol Chem (2002) 1.02

Functional blocking monoclonal antibodies against IL-12p40 homodimer inhibit adoptive transfer of experimental allergic encephalomyelitis. J Immunol (2009) 1.02

Wetting behavior of water and oil droplets in three-phase interfaces for hydrophobicity/philicity and oleophobicity/philicity. Langmuir (2009) 1.02

Up-regulation of neurotrophic factors by cinnamon and its metabolite sodium benzoate: therapeutic implications for neurodegenerative disorders. J Neuroimmune Pharmacol (2013) 1.02

Myelin basic protein-primed T cells induce neurotrophins in glial cells via alphavbeta3 [corrected] integrin. J Biol Chem (2007) 1.01

Suppression of regulatory T cells by IL-12p40 homodimer via nitric oxide. J Immunol (2009) 1.01

Mechanically durable carbon nanotube-composite hierarchical structures with superhydrophobicity, self-cleaning, and low-drag. ACS Nano (2009) 1.01

Expression of genes related to multiple drug resistance and apoptosis in acute leukemia: response to induction chemotherapy. Exp Mol Pathol (2011) 0.99

Friction model for the velocity dependence of nanoscale friction. Nanotechnology (2005) 0.99

Role for cysteinyl leukotrienes in allergen-induced change in circulating dendritic cell number in asthma. J Allergy Clin Immunol (2004) 0.98

Testing NF-κB-based therapy in hemiparkinsonian monkeys. J Neuroimmune Pharmacol (2012) 0.98

Durable Lotus-effect surfaces with hierarchical structure using micro- and nanosized hydrophobic silica particles. J Colloid Interface Sci (2011) 0.98

The adhesion model considering capillarity for gecko attachment system. J R Soc Interface (2008) 0.98

Protection of Tregs, suppression of Th1 and Th17 cells, and amelioration of experimental allergic encephalomyelitis by a physically-modified saline. PLoS One (2012) 0.97

Hydrophobicity, adhesion, and friction properties of nanopatterned polymers and scale dependence for micro- and nanoelectromechanical systems. Nano Lett (2005) 0.97

Effect of spherical Au nanoparticles on nanofriction and wear reduction in dry and liquid environments. Beilstein J Nanotechnol (2012) 0.97

Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide. J Immunol (2010) 0.97

Multiscale effects and capillary interactions in functional biomimetic surfaces for energy conversion and green engineering. Philos Trans A Math Phys Eng Sci (2009) 0.97

Gemfibrozil, a lipid-lowering drug, upregulates IL-1 receptor antagonist in mouse cortical neurons: implications for neuronal self-defense. J Immunol (2012) 0.96

Transparent, superhydrophobic, and wear-resistant coatings on glass and polymer substrates using SiO2, ZnO, and ITO nanoparticles. Langmuir (2012) 0.96

Expression of hemagglutinin esterase protein from recombinant mouse hepatitis virus enhances neurovirulence. J Virol (2005) 0.95

Altered spinal microRNA-146a and the microRNA-183 cluster contribute to osteoarthritic pain in knee joints. J Bone Miner Res (2013) 0.95

Protection of dopaminergic neurons in a mouse model of Parkinson's disease by a physically-modified saline containing charge-stabilized nanobubbles. J Neuroimmune Pharmacol (2014) 0.94

IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1. Glia (2009) 0.94

Synthesis and anticancer activities of 6-amino amonafide derivatives. Anticancer Drugs (2008) 0.94

Effect of stiffness of multi-level hierarchical attachment system on adhesion enhancement. Ultramicroscopy (2007) 0.93

Premature ejaculation: current medical treatment and new directions (CME). J Sex Med (2008) 0.93

Sphingolipids in multiple sclerosis. Neuromolecular Med (2010) 0.93

Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy. J Biol Chem (2013) 0.92