Published in Chembiochem on July 03, 2012
Crystallization of dienelactone hydrolase in two space groups: structural changes caused by crystal packing. Acta Crystallogr F Struct Biol Commun (2014) 0.75
Structural basis for proofreading during replication of the Escherichia coli chromosome. Structure (2002) 1.98
Alpha/beta hydrolase fold: an update. Protein Pept Lett (2009) 1.26
The structures of the PII proteins from the cyanobacteria Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803. Acta Crystallogr D Biol Crystallogr (2003) 1.16
Comparing the organophosphorus and carbamate insecticide resistance mutations in cholin- and carboxyl-esterases. Chem Biol Interact (2005) 1.15
Anomalous scattering analysis of Agrobacterium radiobacter phosphotriesterase: the prominent role of iron in the heterobinuclear active site. Biochem J (2006) 1.14
Hydrolysis of the 5'-p-nitrophenyl ester of TMP by the proofreading exonuclease (epsilon) subunit of Escherichia coli DNA polymerase III. Biochemistry (2002) 1.14
In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase. J Mol Biol (2007) 1.09
The structure and function of a novel glycerophosphodiesterase from Enterobacter aerogenes. J Mol Biol (2007) 1.07
Growth of Escherichia coli coexpressing phosphotriesterase and glycerophosphodiester phosphodiesterase, using paraoxon as the sole phosphorus source. Appl Environ Microbiol (2004) 1.05
Characterization of the phenylurea hydrolases A and B: founding members of a novel amidohydrolase subgroup. Biochem J (2009) 0.98
The effects of substrate orientation on the mechanism of a phosphotriesterase. Org Biomol Chem (2005) 0.98
Structure and function of an insect α-carboxylesterase (αEsterase7) associated with insecticide resistance. Proc Natl Acad Sci U S A (2013) 0.97
Structure of the N-terminal domain of Escherichia coli glutamine synthetase adenylyltransferase. Structure (2004) 0.96
The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism. Biochim Biophys Acta (2005) 0.96
Improving a natural enzyme activity through incorporation of unnatural amino acids. J Am Chem Soc (2010) 0.96
Improving protein solubility: the use of the Escherichia coli dihydrofolate reductase gene as a fusion reporter. Protein Expr Purif (2005) 0.92
Binuclear metallohydrolases: complex mechanistic strategies for a simple chemical reaction. Acc Chem Res (2012) 0.90
Molecular fibers and wires in solid-state and solution self-assemblies of cyclodextrin [2]rotaxanes. Org Lett (2008) 0.89
A novel functional epitope formed by domains 1 and 4 of the human common beta-subunit is involved in receptor activation by granulocyte macrophage colony-stimulating factor and interleukin 5. J Biol Chem (2003) 0.88
The unusual bifunctional catalysis of epimerization and desaturation by carbapenem synthase. J Am Chem Soc (2004) 0.87
Interleukin-3 binding to the murine betaIL-3 and human betac receptors involves functional epitopes formed by domains 1 and 4 of different protein chains. J Biol Chem (2004) 0.87
Expression, purification, crystallization, and preliminary X-ray analysis of the N-terminal domain of Escherichia coli adenylyl transferase. Protein Expr Purif (2004) 0.86
Structure of the adenylylation domain of E. coli glutamine synthetase adenylyl transferase: evidence for gene duplication and evolution of a new active site. J Mol Biol (2009) 0.85
Clostridium carboxidivorans strain P7T recombinant formate dehydrogenase catalyzes reduction of CO(2) to formate. Appl Environ Microbiol (2012) 0.85
Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes. J Am Chem Soc (2008) 0.84
3-mercapto-1,2,4-triazoles and N-acylated thiosemicarbazides as metallo-β-lactamase inhibitors. Bioorg Med Chem Lett (2011) 0.83
Phosphate-bound structure of an organophosphate-degrading enzyme from Agrobacterium radiobacter. J Inorg Biochem (2011) 0.83
Structural flexibility enhances the reactivity of the bioremediator glycerophosphodiesterase by fine-tuning its mechanism of hydrolysis. J Am Chem Soc (2009) 0.82
Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase. Acta Crystallogr D Biol Crystallogr (2005) 0.82
Directed evolution combined with rational design increases activity of GpdQ toward a non-physiological substrate and alters the oligomeric structure of the enzyme. Protein Eng Des Sel (2011) 0.82
Hydrogen abstraction by chlorine atom from small organic molecules containing amino acid functionalities: an assessment of theoretical procedures. J Phys Chem A (2009) 0.81
The domains carrying the opposing activities in adenylyltransferase are separated by a central regulatory domain. FEBS J (2007) 0.81
The foundation of a light driven molecular muscle based on stilbene and alpha-cyclodextrin. Chem Commun (Camb) (2008) 0.81
Cooperative binding and stabilization of the medicinal pigment curcumin by diamide linked γ-cyclodextrin dimers: a spectroscopic characterization. J Phys Chem B (2010) 0.80
Fermentative glycolysis with purified Escherichia coli enzymes for in vitro ATP production and evaluating an engineered enzyme. J Biotechnol (2011) 0.80
Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme. Biochem J (2010) 0.80
Peculiar stability of amino acids and peptides from a radical perspective. J Am Chem Soc (2009) 0.80
The identification of new metallo-β-lactamase inhibitor leads from fragment-based screening. Bioorg Med Chem Lett (2011) 0.80
Electronic and geometric structures of the organophosphate-degrading enzyme from Agrobacterium radiobacter (OpdA). J Biol Inorg Chem (2011) 0.79
Inhibition of neutrophil leukotriene B4 production by a novel synthetic N-3 polyunsaturated fatty acid analogue, beta-oxa 21:3n-3. J Immunol (2003) 0.79
The role of Zn-OR and Zn-OH nucleophiles and the influence of para-substituents in the reactions of binuclear phosphatase mimetics. Dalton Trans (2011) 0.79
Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.79
Design of radical-resistant amino acid residues: a combined theoretical and experimental investigation. J Am Chem Soc (2003) 0.79
Gas-phase regiocontrolled generation of charged amino acid and peptide radicals. Chem Commun (Camb) (2006) 0.79
Diamide linked γ-cyclodextrin dimers as molecular-scale delivery systems for the medicinal pigment curcumin to prostate cancer cells. Mol Pharm (2013) 0.79
Pharmacokinetics of OpdA, an organophosphorus hydrolase, in the African green monkey. Biochem Pharmacol (2010) 0.79
Electronic structure analysis of the dinuclear metal center in the bioremediator glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. Inorg Chem (2010) 0.79
Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search. ACS Chem Biol (2014) 0.78
The purification, crystallization and preliminary diffraction of a glycerophosphodiesterase from Enterobacter aerogenes. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.78
The organophosphate-degrading enzyme from Agrobacterium radiobacter displays mechanistic flexibility for catalysis. Biochem J (2010) 0.78
Identification and characterization of an unusual metallo-β-lactamase from Serratia proteamaculans. J Biol Inorg Chem (2013) 0.77
Reactivities of amino acid derivatives toward hydrogen abstraction by Cl• and OH•. J Org Chem (2012) 0.77
Incorporation of chlorinated analogues of aliphatic amino acids during cell-free protein synthesis. Chem Commun (Camb) (2010) 0.77
Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes. Dalton Trans (2013) 0.77
Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH). J Biol Inorg Chem (2014) 0.77
Synthesis and activity of analogues of the isoleucyl tRNA synthetase inhibitor SB-203207. Bioorg Med Chem (2003) 0.77
Promiscuity comes at a price: catalytic versatility vs efficiency in different metal ion derivatives of the potential bioremediator GpdQ. Biochim Biophys Acta (2012) 0.77
Validation of the distal effect of electron-withdrawing groups on the stability of peptide enolates and its exploitation in the controlled stereochemical inversion of amino acid derivatives. J Org Chem (2011) 0.77
The distal effect of electron-withdrawing groups and hydrogen bonding on the stability of peptide enolates. J Am Chem Soc (2010) 0.76
Gas-phase ion-molecule reactions using regioselectively generated radical cations to model oxidative damage and probe radical sites in peptides. Org Biomol Chem (2011) 0.76
The bioremediator glycerophosphodiesterase employs a non-processive mechanism for hydrolysis. J Inorg Biochem (2009) 0.76
Inhibition of peptidylglycine alpha-amidating monooxygenase by exploitation of factors affecting the stability and ease of formation of glycyl radicals. J Am Chem Soc (2004) 0.76
The role of inhibition in enzyme evolution. Chem Biol (2004) 0.76
In vitro directed evolution of enzymes expressed by E. coli in microtiter plates. Methods Mol Biol (2013) 0.76
Synthesis and kinetic testing of tetrahydropyrimidine-2-thione and pyrrole derivatives as inhibitors of the metallo-β-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa. Chem Biol Drug Des (2012) 0.76
Formate production through biocatalysis. Bioengineered (2013) 0.76
Prohormone-substrate peptide sequence recognition by peptidylglycine α-amidating monooxygenase and its reflection in increased glycolate inhibitor potency. Bioorg Med Chem Lett (2012) 0.76
Directed evolution of yeast pyruvate decarboxylase 1 for attenuated regulation and increased stability. Biochemistry (2008) 0.76
Cloning, expression, purification, crystallization and preliminary X-ray studies of a pyridoxine 5'-phosphate oxidase from Mycobacterium smegmatis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.76
Harnessing the energy of molecular recognition in a nanomachine having a photochemical on/off switch. J Am Chem Soc (2006) 0.75
Hydrogen from formic acid through its selective disproportionation over sodium germanate--a non-transition-metal catalysis system. Angew Chem Int Ed Engl (2014) 0.75
Expression, purification and crystallization of the C-terminal domain of Escherichia coli adenylyltransferase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.75
Synthesis of alpha-cyclodextrin [2]-rotaxanes using chlorotriazine capping reagents. Org Biomol Chem (2008) 0.75
Factors affecting the relative and absolute rates of beta-scission of alkoxythiocarbonyl radicals and alkoxycarbonyl radicals. J Org Chem (2006) 0.75
In situ deprotection and incorporation of unnatural amino acids during cell-free protein synthesis. Chemistry (2013) 0.75
Hydrogen abstraction by chlorine atom from amino acids: remarkable influence of polar effects on regioselectivity. J Am Chem Soc (2011) 0.75
Installation of a ratchet tooth and pawl to restrict rotation in a cyclodextrin rotaxane. Chemistry (2003) 0.75
4-Alkoxycarbonyl- and aminocarbonyl-substituted isoxazoles as masked acrylates and acrylamides in the asymmetric synthesis of delta2-isoxazolines. J Org Chem (2006) 0.75
Diazacoronand linked beta-cyclodextrin dimer complexes of Brilliant Yellow tetraanion and their sodium(I) analogues. Org Biomol Chem (2003) 0.75
Aromatic chlorination of omega-phenylalkylamines and omega-phenylalkylamides in carbon tetrachloride and alpha,alpha,alpha-trifluorotoluene. Org Biomol Chem (2006) 0.75
Separated and aligned molecular fibres in solid state self-assemblies of cyclodextrin [2]rotaxanes. Chemistry (2003) 0.75
Screening libraries for improved solubility: using E. coli dihydrofolate reductase as a reporter. Methods Mol Biol (2013) 0.75
Compensatory stabilizing role of surface mutations during the directed evolution of dienelactone hydrolase for enhanced activity. Protein J (2015) 0.75
Hydrogen-atom abstraction from a model amino acid: dependence on the attacking radical. J Phys Chem B (2014) 0.75
Cyclodextrin complexation of a stilbene and the self-assembly of a simple molecular device. Org Biomol Chem (2003) 0.75
Cyclodextrin and modified cyclodextrin complexes of E-4-tert-butylphenyl-4'-oxyazobenzene: UV-visible, 1H NMR and ab initio studies. Org Biomol Chem (2005) 0.75
Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry. J Biol Inorg Chem (2014) 0.75
Detection of Biosynthetic Precursors, Discovery of Glycosylated Forms and Homeostasis of Calcitonin in Human Cancer Cells. Anal Chem (2017) 0.75
Functional effects of amino acid substitutions within the large binding pocket of the phosphotriesterase OpdA from Agrobacterium sp. P230. FEMS Microbiol Lett (2006) 0.75
Intra- and intermolecular complexation in C6 monoazacoronand substituted cyclodextrins. Org Biomol Chem (2004) 0.75
Aminocyclodextrins to facilitate the deprotonation of 4-tert-butyl-alpha-nitrotoluene. Org Biomol Chem (2005) 0.75
Reversal of regioselectivity and enhancement of rates of nitrile oxide cycloadditions through transient attachment of dipolarophiles to cyclodextrins. Chemistry (2006) 0.75
Cadmium(II) complexes of the glycerophosphodiester-degrading enzyme GpdQ and a biomimetic N,O ligand. J Biol Inorg Chem (2008) 0.75
Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals. J Phys Chem A (2006) 0.75
The Escherichia coli glucuronylsynthase promoted synthesis of steroid glucuronides: improved practicality and broader scope. Org Biomol Chem (2014) 0.75