A new approach to simultaneously quantify both TCR α- and β-chain diversity after adoptive immunotherapy.

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Published in Clin Cancer Res on July 03, 2012

Authors

Minying Zhang1, Sourindra Maiti, Chantale Bernatchez, Helen Huls, Brian Rabinovich, Richard E Champlin, Luis M Vence, Patrick Hwu, Laszlo Radvanyi, Laurence J N Cooper

Author Affiliations

1: Department of Melanoma Medical Oncology, Unit 904, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

Associated clinical trials:

Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma | NCT00338377

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