Published in PLoS Pathog on June 28, 2012
Comprehensive analysis of host cellular interactions with human papillomavirus E6 proteins identifies new E6 binding partners and reflects viral diversity. J Virol (2012) 1.28
Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA. PLoS Pathog (2013) 1.00
E2 proteins of high risk human papillomaviruses down-modulate STING and IFN-κ transcription in keratinocytes. PLoS One (2014) 0.99
HIV Infection Alters the Spectrum of HPV Subtypes Found in Cervical Smears and Carcinomas from Kenyan Women. Open Virol J (2013) 0.99
Beta genus papillomaviruses and skin cancer. Virology (2015) 0.96
Proteomic approaches to the study of papillomavirus-host interactions. Virology (2013) 0.94
The HPV E2-Host Protein-Protein Interactions: A Complex Hijacking of the Cellular Network. Open Virol J (2012) 0.86
Productive infection of bovine papillomavirus type 2 in the urothelial cells of naturally occurring urinary bladder tumors in cattle and water buffaloes. PLoS One (2013) 0.85
Cutaneous Squamous Cell Carcinomas in Organ Transplant Recipients. J Clin Med (2015) 0.83
Identification and comparative analysis of hepatitis C virus-host cell protein interactions. Mol Biosyst (2013) 0.83
TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication. PLoS One (2013) 0.82
BRD4 Phosphorylation Regulates HPV E2-Mediated Viral Transcription, Origin Replication, and Cellular MMP-9 Expression. Cell Rep (2016) 0.81
Virus-host interactomics: new insights and opportunities for antiviral drug discovery. Genome Med (2014) 0.81
Signatures of pleiotropy, economy and convergent evolution in a domain-resolved map of human-virus protein-protein interaction networks. PLoS Pathog (2013) 0.80
A proteomic approach to discover and compare interacting partners of papillomavirus E2 proteins from diverse phylogenetic groups. Proteomics (2015) 0.80
Control of human papillomavirus gene expression by alternative splicing. Virus Res (2016) 0.78
Perspective: The Promise of Proteomics in the Study of Oncogenic Viruses. Mol Cell Proteomics (2017) 0.78
Interaction between ORF24 and ORF34 in the Kaposi's Sarcoma-Associated Herpesvirus Late Gene Transcription Factor Complex Is Essential for Viral Late Gene Expression. J Virol (2015) 0.77
Stranglehold on the spindle assembly checkpoint: the human papillomavirus E2 protein provokes BUBR1-dependent aneuploidy. Cell Cycle (2015) 0.77
The role of ubiquitin and ubiquitin-like modification systems in papillomavirus biology. Viruses (2014) 0.76
Human Papillomavirus E2 Protein: Linking Replication, Transcription, and RNA Processing. J Virol (2016) 0.76
Association of human papillomavirus type 16 E2 with Rad50-interacting protein 1 enhances viral DNA replication. J Virol (2016) 0.75
A comparative approach to characterize the landscape of host-pathogen protein-protein interactions. J Vis Exp (2013) 0.75
Human papillomavirus E2 protein: a potential key regulator of viral cell pathogenesis. Pathog Glob Health (2012) 0.75
CCHCR1 interacts specifically with the E2 protein of human papillomavirus type 16 on a surface overlapping BRD4 binding. PLoS One (2014) 0.75
KINASE ACTIVITY OF FIBROBLAST GROWTH FACTOR RECEPTOR-3 REGULATES ACTIVITY OF THE PAPILLOMAVIRUS E2 PROTEIN. J Virol (2017) 0.75
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc Natl Acad Sci U S A (2001) 33.71
Cytoscape 2.8: new features for data integration and network visualization. Bioinformatics (2010) 26.76
Towards a proteome-scale map of the human protein-protein interaction network. Nature (2005) 24.76
Java Treeview--extensible visualization of microarray data. Bioinformatics (2004) 24.12
MINT: a Molecular INTeraction database. FEBS Lett (2002) 17.21
Classification of papillomaviruses. Virology (2004) 14.16
An empirical framework for binary interactome mapping. Nat Methods (2008) 6.59
Papillomaviruses in the causation of human cancers - a brief historical account. Virology (2009) 5.46
Efficient intracellular assembly of papillomaviral vectors. J Virol (2004) 5.36
An experimentally derived confidence score for binary protein-protein interactions. Nat Methods (2008) 5.27
The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2. Mol Cell (2002) 3.99
Epstein-Barr virus and virus human protein interaction maps. Proc Natl Acad Sci U S A (2007) 3.50
Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes. PLoS Comput Biol (2006) 3.23
The landscape of human proteins interacting with viruses and other pathogens. PLoS Pathog (2008) 3.11
Hepatitis C virus infection protein network. Mol Syst Biol (2008) 2.91
Manipulation of host cell death pathways during microbial infections. Cell Host Microbe (2010) 2.21
Structure of the papillomavirus DNA-tethering complex E2:Brd4 and a peptide that ablates HPV chromosomal association. Mol Cell (2006) 2.11
Translational inhibition in vitro of human papillomavirus type 16 L2 mRNA mediated through interaction with heterogenous ribonucleoprotein K and poly(rC)-binding proteins 1 and 2. J Biol Chem (1998) 1.88
Where have all the interactions gone? Estimating the coverage of two-hybrid protein interaction maps. PLoS Comput Biol (2007) 1.81
Human Vam6p promotes lysosome clustering and fusion in vivo. J Cell Biol (2001) 1.75
VirHostNet: a knowledge base for the management and the analysis of proteome-wide virus-host interaction networks. Nucleic Acids Res (2008) 1.71
The human papillomavirus type 8 E2 protein induces skin tumors in transgenic mice. J Invest Dermatol (2008) 1.71
Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression. Proc Natl Acad Sci U S A (2010) 1.57
Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes. Mol Biol Cell (2008) 1.49
Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4. Virology (2006) 1.47
Molecular mechanisms of human papillomavirus-induced carcinogenesis. Public Health Genomics (2009) 1.45
Benchmarking a luciferase complementation assay for detecting protein complexes. Nat Methods (2011) 1.44
Nucleo-cytoplasmic shuttling of high risk human Papillomavirus E2 proteins induces apoptosis. J Biol Chem (2005) 1.41
A human papillomavirus E2 transcriptional activator. The interactions with cellular splicing factors and potential function in pre-mRNA processing. J Biol Chem (1999) 1.37
Human papillomavirus: the burden of infection. Obstet Gynecol Surv (2006) 1.24
Stability of the human papillomavirus type 18 E2 protein is regulated by a proteasome degradation pathway through its amino-terminal transactivation domain. J Virol (2001) 1.19
Enhanced transcriptional activation by E2 proteins from the oncogenic human papillomaviruses. J Virol (1996) 1.19
Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4. J Virol (2009) 1.13
High-risk but not low-risk HPV E2 proteins bind to the APC activators Cdh1 and Cdc20 and cause genomic instability. Cell Cycle (2005) 1.12
Transcriptional activity among high and low risk human papillomavirus E2 proteins correlates with E2 DNA binding. J Biol Chem (2002) 1.10
ViralORFeome: an integrated database to generate a versatile collection of viral ORFs. Nucleic Acids Res (2009) 1.04
Partitioning viral genomes in mitosis: same idea, different targets. Cell Cycle (2006) 1.03
E2 proteins from high- and low-risk human papillomavirus types differ in their ability to bind p53 and induce apoptotic cell death. J Virol (2006) 1.03
Brd4 regulation of papillomavirus protein E2 stability. J Virol (2009) 1.02
BPV1 E2 protein enhances packaging of full-length plasmid DNA in BPV1 pseudovirions. Virology (2000) 1.00
Cellular receptor binding and entry of human papillomavirus. Virol J (2010) 0.99
Tax1BP1 interacts with papillomavirus E2 and regulates E2-dependent transcription and stability. J Virol (2008) 0.97
Mad2 inhibits the mitotic kinesin MKlp2. J Cell Biol (2010) 0.97
Comprehensive comparison of the interaction of the E2 master regulator with its cognate target DNA sites in 73 human papillomavirus types by sequence statistics. Nucleic Acids Res (2007) 0.96
Control of papillomavirus DNA replication and transcription. Semin Cancer Biol (1996) 0.96
Tumor suppressor or oncogene? A critical role of the human papillomavirus (HPV) E2 protein in cervical cancer progression. Am J Cancer Res (2011) 0.91
Direct activation of caspase 8 by the proapoptotic E2 protein of HPV18 independent of adaptor proteins. Cell Death Differ (2008) 0.89
Human papillomavirus infection of non-melanoma skin cancers in immunocompetent hosts. Cancer Lett (2000) 0.87
EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy. Nat Med (2011) 6.21
Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis. N Engl J Med (2011) 2.93
Autophagy induction by the pathogen receptor CD46. Cell Host Microbe (2009) 2.39
A variant in the CD209 promoter is associated with severity of dengue disease. Nat Genet (2005) 2.31
A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells. PLoS Pathog (2008) 2.12
IRGM is a common target of RNA viruses that subvert the autophagy network. PLoS Pathog (2011) 2.09
Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine. Genome Res (2002) 2.04
Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis. Nat Genet (2002) 1.90
Hepatitis C virus particles and lipoprotein metabolism. Semin Liver Dis (2005) 1.74
VirHostNet: a knowledge base for the management and the analysis of proteome-wide virus-host interaction networks. Nucleic Acids Res (2008) 1.71
Genomic definition of hypervirulent and multidrug-resistant Klebsiella pneumoniae clonal groups. Emerg Infect Dis (2014) 1.65
The PHD domain of Np95 (mUHRF1) is involved in large-scale reorganization of pericentromeric heterochromatin. Mol Biol Cell (2008) 1.53
A novel design of whole-genome microarray probes for Saccharomyces cerevisiae which minimizes cross-hybridization. BMC Genomics (2003) 1.51
Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-alpha/beta signaling. Virology (2007) 1.44
Benchmarking a luciferase complementation assay for detecting protein complexes. Nat Methods (2011) 1.44
Targeting of incoming retroviral Gag to the centrosome involves a direct interaction with the dynein light chain 8. J Cell Sci (2003) 1.44
Nucleo-cytoplasmic shuttling of high risk human Papillomavirus E2 proteins induces apoptosis. J Biol Chem (2005) 1.41
Preferential association of Hepatitis C virus with apolipoprotein B48-containing lipoproteins. J Gen Virol (2006) 1.39
A DNA microarray for fission yeast: minimal changes in global gene expression after temperature shift. Yeast (2004) 1.38
HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex. Cell Host Microbe (2013) 1.37
Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses. J Exp Med (2007) 1.33
Genetically encoded chloride indicator with improved sensitivity. J Neurosci Methods (2008) 1.32
Secretion of hepatitis C virus envelope glycoproteins depends on assembly of apolipoprotein B positive lipoproteins. PLoS One (2009) 1.31
Identification and targeting of an interaction between a tyrosine motif within hepatitis C virus core protein and AP2M1 essential for viral assembly. PLoS Pathog (2012) 1.24
Strand specific quantitative real-time PCR to study replication of hepatitis C virus genome. J Virol Methods (2004) 1.21
1-Methyl-tryptophan can interfere with TLR signaling in dendritic cells independently of IDO activity. J Immunol (2006) 1.15
When the human viral infectome and diseasome networks collide: towards a systems biology platform for the aetiology of human diseases. BMC Syst Biol (2011) 1.15
Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein. J Biol Chem (2008) 1.14
Genomic organization of amplified MYC genes suggests distinct mechanisms of amplification in tumorigenesis. Cancer Res (2005) 1.14
Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component. J Virol (2012) 1.12
Inhibition of IFN-alpha/beta signaling by two discrete peptides within measles virus V protein that specifically bind STAT1 and STAT2. Virology (2008) 1.12
Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS. J Biol Chem (2009) 1.11
Localization of the yeast RNA polymerase I-specific subunits. EMBO J (2002) 1.10
The EVER proteins as a natural barrier against papillomaviruses: a new insight into the pathogenesis of human papillomavirus infections. Microbiol Mol Biol Rev (2009) 1.09
[The virtual infected cell: a systems biology rational for antiviral drug discovery]. Med Sci (Paris) (2010) 1.07
Defective innate cell response and lymph node infiltration specify Yersinia pestis infection. PLoS One (2008) 1.06
E6 proteins from diverse papillomaviruses self-associate both in vitro and in vivo. J Mol Biol (2009) 1.05
Protein transfer into human cells by VSV-G-induced nanovesicles. Mol Ther (2011) 1.04
The human TREX-2 complex is stably associated with the nuclear pore basket. J Cell Sci (2013) 1.04
High expression of antioxidant proteins in dendritic cells: possible implications in atherosclerosis. Mol Cell Proteomics (2006) 1.03
Expression of hepatitis C virus proteins in epithelial intestinal cells in vivo. J Gen Virol (2004) 1.03
Flavivirus NS3 and NS5 proteins interaction network: a high-throughput yeast two-hybrid screen. BMC Microbiol (2011) 1.01
Species-specific impact of the autophagy machinery on Chikungunya virus infection. EMBO Rep (2013) 1.01
Mature dendritic cell generation promoted by lysophosphatidylcholine. J Immunol (2002) 1.01
Rabies virus matrix protein interplay with eIF3, new insights into rabies virus pathogenesis. Nucleic Acids Res (2007) 0.99
Enhancement of genotype 1 hepatitis C virus replication by bile acids through FXR. J Hepatol (2007) 0.98
Human papillomavirus type 5 E6 oncoprotein represses the transforming growth factor beta signaling pathway by binding to SMAD3. J Virol (2006) 0.98
RReportGenerator: automatic reports from routine statistical analysis using R. Bioinformatics (2007) 0.97
EVER proteins, key elements of the natural anti-human papillomavirus barrier, are regulated upon T-cell activation. PLoS One (2012) 0.97
The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication. PLoS Pathog (2013) 0.97
A genomic approach reveals a novel mitotic pathway in papillomavirus carcinogenesis. Cancer Res (2004) 0.96
Effects of HPV-16 E5, E6 and E7 proteins on survival, adhesion, migration and invasion of trophoblastic cells. Carcinogenesis (2009) 0.96
Cottontail rabbit papillomavirus E8 protein is essential for wart formation and provides new insights into viral pathogenesis. J Virol (2006) 0.96
Integrated version of reverse two-hybrid system for the postproteomic era. Methods Enzymol (2002) 0.95
A novel expression cassette of lyssavirus shows that the distantly related Mokola virus can rescue a defective rabies virus genome. J Virol (2002) 0.95
Generation and comprehensive analysis of an influenza virus polymerase cellular interaction network. J Virol (2011) 0.95
Role of Zn2+ ions in host-virus interactions. J Virol (2008) 0.95
HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replication. J Virol (2012) 0.93
Proteomic analysis of virus-host interactions in an infectious context using recombinant viruses. Mol Cell Proteomics (2011) 0.93
Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase. Methods (2012) 0.93
Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity. PLoS Pathog (2013) 0.93
The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism. J Physiol (2011) 0.92
Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches. Mol Cell Proteomics (2013) 0.92
Sensing environmental lipids by dendritic cell modulates its function. J Immunol (2004) 0.92
Lysophosphatidylcholine is a natural adjuvant that initiates cellular immune responses. Vaccine (2005) 0.92
GeneFizz: A web tool to compare genetic (coding/non-coding) and physical (helix/coil) segmentations of DNA sequences. Gene discovery and evolutionary perspectives. Nucleic Acids Res (2003) 0.91
Human importin alpha and RNA do not compete for binding to influenza A virus nucleoprotein. Virology (2010) 0.91
Viruses and interactomes in translation. Mol Cell Proteomics (2012) 0.91
Transactivation of the hepatitis B virus core promoter by the nuclear receptor FXRalpha. J Virol (2008) 0.90
RNAi: a powerful tool to unravel hepatitis C virus-host interactions within the infectious life cycle. J Hepatol (2007) 0.89
Activity of hexokinase is increased by its interaction with hepatitis C virus protein NS5A. J Virol (2014) 0.89
Antiviral drug discovery strategy using combinatorial libraries of structurally constrained peptides. J Virol (2004) 0.89
Peptides that mimic the amino-terminal end of the rabies virus phosphoprotein have antiviral activity. J Virol (2009) 0.89
PhEVER: a database for the global exploration of virus-host evolutionary relationships. Nucleic Acids Res (2010) 0.88
Secretory phospholipase A2 induces dendritic cell maturation. Eur J Immunol (2004) 0.88
Effects of the proteasome inhibitor ritonavir on glioma growth in vitro and in vivo. Mol Cancer Ther (2004) 0.88
Genetic screens for the control of influenza virus replication: from meta-analysis to drug discovery. Mol Biosyst (2012) 0.87
High plasma level of nucleocapsid-free envelope glycoprotein-positive lipoproteins in hepatitis C patients. Hepatology (2012) 0.87
New horizons for antiviral drug discovery from virus-host protein interaction networks. Curr Opin Virol (2012) 0.87
Exploration of binary virus-host interactions using an infectious protein complementation assay. Mol Cell Proteomics (2013) 0.86
Epstein-Barr virus protein EB2 stimulates cytoplasmic mRNA accumulation by counteracting the deleterious effects of SRp20 on viral mRNAs. Nucleic Acids Res (2012) 0.86
Mitochondrial dysfunction in lyssavirus-induced apoptosis. J Virol (2008) 0.86
pISTil: a pipeline for yeast two-hybrid Interaction Sequence Tags identification and analysis. BMC Res Notes (2009) 0.86
Th1 disabled function in response to TLR4 stimulation of monocyte-derived DC from patients chronically-infected by hepatitis C virus. PLoS One (2008) 0.86