Published in Mucosal Immunol on July 04, 2012
A role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast. PLoS One (2013) 0.91
Human fetal membranes generate distinct cytokine profiles in response to bacterial Toll-like receptor and nod-like receptor agonists. Biol Reprod (2014) 0.90
Recognition of Extracellular Bacteria by NLRs and Its Role in the Development of Adaptive Immunity. Front Immunol (2013) 0.87
The inflammasome in alcoholic hepatitis: Its relationship with Mallory-Denk body formation. Exp Mol Pathol (2014) 0.87
The Interplay between NLRs and Autophagy in Immunity and Inflammation. Front Immunol (2013) 0.86
Waddlia chondrophila infects and multiplies in ovine trophoblast cells stimulating an inflammatory immune response. PLoS One (2014) 0.85
Chlamydia trachomatis infection results in a modest pro-inflammatory cytokine response and a decrease in T cell chemokine secretion in human polarized endocervical epithelial cells. Cytokine (2013) 0.83
Viral single stranded RNA induces a trophoblast pro-inflammatory and antiviral response in a TLR8-dependent and -independent manner. Biol Reprod (2014) 0.81
A Role for the Inflammasome in Spontaneous Labor at Term. Am J Reprod Immunol (2016) 0.80
Chlamydiaphage φCPG1 Capsid Protein Vp1 Inhibits Chlamydia trachomatis Growth via the Mitogen-Activated Protein Kinase Pathway. Viruses (2016) 0.79
Chlamydial Plasmid-Dependent Pathogenicity. Trends Microbiol (2016) 0.77
Glucose and metformin modulate human first trimester trophoblast function: a model and potential therapy for diabetes-associated uteroplacental insufficiency. Am J Reprod Immunol (2014) 0.77
Prion pathogenesis in the absence of NLRP3/ASC inflammasomes. PLoS One (2015) 0.77
Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Am J Obstet Gynecol (2016) 0.76
Caspase-12 silencing attenuates inhibitory effects of cigarette smoke extract on NOD1 signaling and hBDs expression in human oral mucosal epithelial cells. PLoS One (2014) 0.76
Chlamydial plasmid-encoded protein pORF5 induces production of IL-1β and IL-18 via NALP3 inflammasome activation and p38 MAPK pathway. Int J Clin Exp Med (2015) 0.76
Biological functions of thyroid hormone in placenta. Int J Mol Sci (2015) 0.75
Inflammasomes and Their Role in Innate Immunity of Sexually Transmitted Infections. Front Immunol (2016) 0.75
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity (2009) 6.37
Pathogen recognition by the innate immune system. Int Rev Immunol (2011) 5.76
Establishment and characterization of first trimester human trophoblast cells with extended lifespan. Exp Cell Res (1993) 3.59
IL-1beta processing in host defense: beyond the inflammasomes. PLoS Pathog (2010) 2.54
Toll-like receptor-2, but not Toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection. J Immunol (2003) 2.44
Molecular circuits shared by placental and cancer cells, and their implications in the proliferative, invasive and migratory capacities of trophoblasts. Hum Reprod Update (2006) 2.15
Mechanisms of interleukin-1beta release. Immunobiology (2009) 1.93
Lower genital tract infection and endometritis: insight into subclinical pelvic inflammatory disease. Obstet Gynecol (2002) 1.85
Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection. Infect Immun (2007) 1.85
Localization of TLR2 and MyD88 to Chlamydia trachomatis inclusions. Evidence for signaling by intracellular TLR2 during infection with an obligate intracellular pathogen. J Biol Chem (2005) 1.55
The role of placental exosomes in reproduction. Am J Reprod Immunol (2010) 1.53
Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae. Circ Res (2005) 1.50
Emerging role of Chlamydia and Chlamydia-like organisms in adverse pregnancy outcomes. Curr Opin Infect Dis (2008) 1.49
Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum. Cell Microbiol (2006) 1.44
Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome. J Immunol (2010) 1.42
ATP treatment of human monocytes promotes caspase-1 maturation and externalization. J Biol Chem (1999) 1.41
Signalling of toll-like receptors. Handb Exp Pharmacol (2008) 1.40
Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis. J Biol Chem (2009) 1.37
Control of infection by pyroptosis and autophagy: role of TLR and NLR. Cell Mol Life Sci (2010) 1.35
Chlamydia trachomatis induces expression of IFN-gamma-inducible protein 10 and IFN-beta independent of TLR2 and TLR4, but largely dependent on MyD88. J Immunol (2005) 1.35
Toll-like receptors' two-edged sword: when immunity meets apoptosis. Eur J Immunol (2007) 1.32
The cytosolic pattern recognition receptor NOD1 induces inflammatory interleukin-8 during Chlamydia trachomatis infection. Infect Immun (2008) 1.28
Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection. PLoS One (2011) 1.25
The Golgi-associated protein p115 mediates the secretion of macrophage migration inhibitory factor. J Immunol (2009) 1.25
Nod1, a CARD protein, enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1. Biochem Biophys Res Commun (2002) 1.23
Critical role for interleukin-1beta (IL-1beta) during Chlamydia muridarum genital infection and bacterial replication-independent secretion of IL-1beta in mouse macrophages. Infect Immun (2009) 1.19
Nod-like receptors: sentinels at host membranes. Curr Opin Immunol (2010) 1.18
Remodelling at the maternal-fetal interface: relevance to human pregnancy disorders. Reproduction (2010) 1.16
Differential regulation of inflammatory cytokine secretion by human dendritic cells upon Chlamydia trachomatis infection. Infect Immun (2004) 1.13
The isolation and characterization of a novel telomerase immortalized first trimester trophoblast cell line, Swan 71. Placenta (2009) 1.11
Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway. Am J Reprod Immunol (2009) 1.08
Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages. J Biol Chem (2011) 1.07
Chlamydial infection of monocytes stimulates IL-1beta secretion through activation of the NLRP3 inflammasome. Microbes Infect (2010) 1.06
Role of Chlamydia trachomatis in miscarriage. Emerg Infect Dis (2011) 1.06
Is the trophoblast an immune regulator? The role of Toll-like receptors during pregnancy. Crit Rev Immunol (2005) 1.06
Female genital Chlamydia trachomatis infection: where are we heading? Arch Gynecol Obstet (2012) 1.06
TLR6 modulates first trimester trophoblast responses to peptidoglycan. J Immunol (2008) 1.03
Nod1 activation by bacterial iE-DAP induces maternal-fetal inflammation and preterm labor. J Immunol (2011) 1.02
Pattern recognition at the maternal-fetal interface. Immunol Invest (2008) 1.01
Uric acid induces trophoblast IL-1β production via the inflammasome: implications for the pathogenesis of preeclampsia. Am J Reprod Immunol (2011) 1.00
NOD protein expression and function in first trimester trophoblast cells. Am J Reprod Immunol (2007) 0.99
Preterm birth, infection, and inflammation advances from the study of animal models. Reprod Sci (2010) 0.99
Chlamydia trachomatis and placental inflammation in early preterm delivery. Eur J Epidemiol (2011) 0.94
The role of infection in preterm labour and birth. Hosp Med (2003) 0.93
Modulation of trophoblast angiogenic factor secretion by antiphospholipid antibodies is not reversed by heparin. Am J Reprod Immunol (2011) 0.92
Toll-like receptor-4 (TLR4) mediates human beta-defensin-2 (HBD-2) induction in response to Chlamydia pneumoniae in mononuclear cells. FEMS Immunol Med Microbiol (2009) 0.92
Chlamydia trachomatis infection increases fallopian tube PROKR2 via TLR2 and NFκB activation resulting in a microenvironment predisposed to ectopic pregnancy. Am J Pathol (2010) 0.91
Chlamydia trachomatis infection modulates trophoblast cytokine/chemokine production. J Immunol (2009) 0.89
Immune cell activation by trophoblast-derived microvesicles is mediated by syncytin 1. Immunology (2012) 0.88
A murine model for the study of Chlamydia trachomatis genital infections during pregnancy. Infect Immun (1999) 0.88
Chlamydia trachomatis infection during pregnancy: known unknowns. Discov Med (2011) 0.87
Susceptibility of prostate epithelial cells to Chlamydia muridarum infection and their role in innate immunity by recruitment of intracellular Toll-like receptors 4 and 2 and MyD88 to the inclusion. Infect Immun (2006) 0.87
The role of the Nod-like receptor family in trophoblast innate immune responses. J Reprod Immunol (2011) 0.86
Evidence implicating matrix metalloproteinases in the mechanism underlying accumulation of IL-1beta and neuronal apoptosis in the neocortex of HIV/gp120-exposed rats. Int Rev Neurobiol (2007) 0.86
Chlamydia trachomatis infection of human mesothelial cells alters proinflammatory, procoagulant, and fibrinolytic responses. Infect Immun (1998) 0.82
Trophoblast infection with Chlamydia pneumoniae and adverse pregnancy outcomes associated with placental dysfunction. Am J Obstet Gynecol (2009) 0.82
The PCR assessed prevalence of Chlamydia trachomatis in aborted tissues. Med Wieku Rozwoj (2005) 0.81
Detection of Chlamydia trachomatis intrauterine infection using polymerase chain reaction on chorionic villi. Int J Gynaecol Obstet (1998) 0.79
Chlamydia trachomatis infection of human trophoblast alters estrogen and progesterone biosynthesis: an insight into role of infection in pregnancy sequelae. Int J Med Sci (2007) 0.77
Trophoblast-macrophage interactions: a regulatory network for the protection of pregnancy. Am J Reprod Immunol (2007) 1.30
Pre-eclampsia is associated with dendritic cell recruitment into the uterine decidua. J Pathol (2008) 1.27
Do self-perpetuating B lymphocytes drive human autoimmune disease? Immunology (1999) 1.22
Regulation of chemokine production in response to pro-inflammatory cytokines in first trimester decidual cells. J Reprod Immunol (2006) 1.16
The isolation and characterization of a novel telomerase immortalized first trimester trophoblast cell line, Swan 71. Placenta (2009) 1.11
The incidence of selected vaginal infections among pregnant urban blacks. S Afr Med J (1981) 1.04
Expression of Toll-like receptors in the human decidua. Histol Histopathol (2007) 1.04
Cell type-specific expression and function of toll-like receptors 2 and 4 in human placenta: implications in fetal infection. Placenta (2007) 0.95
Utero-placental haemodynamics in the pathogenesis of pre-eclampsia. Placenta (2009) 0.89
Syncytin 1 in the human placenta. Placenta (2012) 0.88