Published in J Immunol on July 01, 2005
CXCL10/IP-10 in infectious diseases pathogenesis and potential therapeutic implications. Cytokine Growth Factor Rev (2011) 2.09
Interferon-ε protects the female reproductive tract from viral and bacterial infection. Science (2013) 1.73
Stimulator of IFN gene is critical for induction of IFN-beta during Chlamydia muridarum infection. J Immunol (2010) 1.61
STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection. MBio (2013) 1.50
Activation of human monocytes by live Borrelia burgdorferi generates TLR2-dependent and -independent responses which include induction of IFN-beta. PLoS Pathog (2009) 1.47
Intracellular interleukin-1alpha mediates interleukin-8 production induced by Chlamydia trachomatis infection via a mechanism independent of type I interleukin-1 receptor. Infect Immun (2007) 1.37
Type I interferon signaling exacerbates Chlamydia muridarum genital infection in a murine model. Infect Immun (2008) 1.23
Critical role for interleukin-1beta (IL-1beta) during Chlamydia muridarum genital infection and bacterial replication-independent secretion of IL-1beta in mouse macrophages. Infect Immun (2009) 1.19
Chlamydia psittaci genetic variants differ in virulence by modulation of host immunity. J Infect Dis (2011) 1.10
Chlamydial infection of monocytes stimulates IL-1beta secretion through activation of the NLRP3 inflammasome. Microbes Infect (2010) 1.06
Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation. J Immunol (2008) 1.02
Chlamydia muridarum infection elicits a beta interferon response in murine oviduct epithelial cells dependent on interferon regulatory factor 3 and TRIF. Infect Immun (2006) 1.02
Nod1, but not the ASC inflammasome, contributes to induction of IL-1β secretion in human trophoblasts after sensing of Chlamydia trachomatis. Mucosal Immunol (2012) 0.99
Dendritic cells and macrophages in the genitourinary tract. Mucosal Immunol (2008) 0.97
Significant role of IL-1 signaling, but limited role of inflammasome activation, in oviduct pathology during Chlamydia muridarum genital infection. J Immunol (2012) 0.97
cPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatis. J Biol Chem (2010) 0.95
Role for the chlamydial type III secretion apparatus in host cytokine expression. Infect Immun (2008) 0.90
Perforin-2 restricts growth of Chlamydia trachomatis in macrophages. Infect Immun (2013) 0.88
Host chemokine and cytokine response in the endocervix within the first developmental cycle of Chlamydia muridarum. Infect Immun (2009) 0.87
Induction and function of IFNβ during viral and bacterial infection. Crit Rev Immunol (2011) 0.85
MyD88-dependent signaling affects the development of meningococcal sepsis by nonlipooligosaccharide ligands. Infect Immun (2006) 0.85
Interferon regulatory transcription factor 3 protects mice from uterine horn pathology during Chlamydia muridarum genital infection. Infect Immun (2011) 0.82
CD4+ T cell expression of MyD88 is essential for normal resolution of Chlamydia muridarum genital tract infection. J Immunol (2013) 0.81
Secretion of biologically active interferon-gamma inducible protein-10 (IP-10) by Lactococcus lactis. Microb Cell Fact (2008) 0.80
Chlamydia pneumoniae impairs the innate immune response in infected epithelial cells by targeting TRAF3. J Immunol (2013) 0.79
Activities of first-choice antimicrobials against gamma interferon-treated Chlamydia trachomatis differ in hypoxia. Antimicrob Agents Chemother (2013) 0.78
Chlamydia pneumoniae infection in polarized epithelial cell lines. Infect Immun (2010) 0.78
A vaccine formulated with a combination of TLR-2 and TLR-9 adjuvants and the recombinant major outer membrane protein elicits a robust immune response and significant protection against a Chlamydia muridarum challenge. Microbes Infect (2013) 0.77
Role of STAT1 in Chlamydia-Induced Type-1 Interferon Production in Oviduct Epithelial Cells. J Interferon Cytokine Res (2015) 0.76
Analyses of the pathways involved in early- and late-phase induction of IFN-beta during C. muridarum infection of oviduct epithelial cells. PLoS One (2015) 0.75
Multiple roles of Myd88 in the immune response to the plague F1-V vaccine and in protection against an aerosol challenge of Yersinia pestis CO92 in mice. J Immunol Res (2014) 0.75
Update on Chlamydia trachomatis Vaccinology. Clin Vaccine Immunol (2017) 0.75
Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis. Nat Commun (2017) 0.75
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity (2012) 5.08
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J Biol Chem (2006) 4.33
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion. J Exp Med (2003) 2.56
Toll-like receptor-2, but not Toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection. J Immunol (2003) 2.44
Plasmid-deficient Chlamydia muridarum fail to induce immune pathology and protect against oviduct disease. J Immunol (2007) 2.30
The oral microbiota: living with a permanent guest. DNA Cell Biol (2009) 2.19
Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase. PLoS One (2010) 1.85
Activation of the phosphatidylinositol 3-kinase/Akt pathway contributes to survival of primary epithelial cells infected with the periodontal pathogen Porphyromonas gingivalis. Infect Immun (2004) 1.75
Chlamydia and apoptosis: life and death decisions of an intracellular pathogen. Nat Rev Microbiol (2004) 1.63
Stimulator of IFN gene is critical for induction of IFN-beta during Chlamydia muridarum infection. J Immunol (2010) 1.61
Intercellular spreading of Porphyromonas gingivalis infection in primary gingival epithelial cells. Infect Immun (2006) 1.59
Toll-like receptor 2 activation by Chlamydia trachomatis is plasmid dependent, and plasmid-responsive chromosomal loci are coordinately regulated in response to glucose limitation by C. trachomatis but not by C. muridarum. Infect Immun (2011) 1.56
Chlamydia. Nat Rev Microbiol (2004) 1.49
Nonadherence with pediatric human immunodeficiency virus therapy as medical neglect. Pediatrics (2004) 1.46
Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum. Cell Microbiol (2006) 1.44
A mouse model of human adaptive immune functions: HLA-A2.1-/HLA-DR1-transgenic H-2 class I-/class II-knockout mice. Eur J Immunol (2004) 1.43
Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis. J Biol Chem (2009) 1.37
Strain and virulence diversity in the mouse pathogen Chlamydia muridarum. Infect Immun (2009) 1.36
Recruitment of BAD by the Chlamydia trachomatis vacuole correlates with host-cell survival. PLoS Pathog (2006) 1.36
Hypervirulent Chlamydia trachomatis clinical strain is a recombinant between lymphogranuloma venereum (L(2)) and D lineages. MBio (2011) 1.36
ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X7-mediated host-cell apoptosis. Cell Microbiol (2007) 1.33
Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease. J Cell Biol (2008) 1.32
Inhibition of chlamydial infectious activity due to P2X7R-dependent phospholipase D activation. Immunity (2003) 1.31
Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1. J Biol Chem (2010) 1.31
ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected by Porphyromonas gingivalis. Cell Microbiol (2009) 1.29
Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection. PLoS One (2011) 1.25
Type I interferon signaling exacerbates Chlamydia muridarum genital infection in a murine model. Infect Immun (2008) 1.23
Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection. J Exp Med (2011) 1.22
Critical role for interleukin-1beta (IL-1beta) during Chlamydia muridarum genital infection and bacterial replication-independent secretion of IL-1beta in mouse macrophages. Infect Immun (2009) 1.19
Interleukin-17 contributes to generation of Th1 immunity and neutrophil recruitment during Chlamydia muridarum genital tract infection but is not required for macrophage influx or normal resolution of infection. Infect Immun (2010) 1.18
Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection. Pathog Dis (2013) 1.18
Role of Bcl-2 family members in caspase-independent apoptosis during Chlamydia infection. Infect Immun (2002) 1.15
Infectivity acts as in vivo selection for maintenance of the chlamydial cryptic plasmid. Infect Immun (2010) 1.15
Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma. EMBO Mol Med (2012) 1.14
Alarmins, inflammasomes and immunity. Biomed J (2013) 1.13
Role of neutrophils in IL-17-dependent immunity to mucosal candidiasis. J Immunol (2014) 1.13
At the innate frontiers between mother and fetus: linking abortion with complement activation. Immunity (2003) 1.12
Variable expression of surface-exposed polymorphic membrane proteins in in vitro-grown Chlamydia trachomatis. Cell Microbiol (2009) 1.11
Role of proapoptotic BAX in propagation of Chlamydia muridarum (the mouse pneumonitis strain of Chlamydia trachomatis) and the host inflammatory response. J Biol Chem (2002) 1.10
Glutathione levels and BAX activation during apoptosis due to oxidative stress in cells expressing wild-type and mutant cystic fibrosis transmembrane conductance regulator. J Biol Chem (2002) 1.10
A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death. J Biol Chem (2005) 1.10
Leptospiral hemolysins induce proinflammatory cytokines through Toll-like receptor 2-and 4-mediated JNK and NF-κB signaling pathways. PLoS One (2012) 1.09
Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation. Br J Pharmacol (2006) 1.08
Inactivation of the fliY gene encoding a flagellar motor switch protein attenuates mobility and virulence of Leptospira interrogans strain Lai. BMC Microbiol (2009) 1.07
Does bacterial vaginosis cause pelvic inflammatory disease? Sex Transm Dis (2013) 1.06
Effect of the purinergic receptor P2X7 on Chlamydia infection in cervical epithelial cells and vaginally infected mice. J Immunol (2007) 1.05
Two different homing pathways involving integrin β7 and E-selectin significantly influence trafficking of CD4 cells to the genital tract following Chlamydia muridarum infection. Am J Reprod Immunol (2009) 1.05
Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages. Biochem Pharmacol (2005) 1.03
Impact of azithromycin resistance mutations on the virulence and fitness of Chlamydia caviae in guinea pigs. Antimicrob Agents Chemother (2010) 1.02
Role of extracellular nucleotides in the immune response against intracellular bacteria and protozoan parasites. Microbes Infect (2012) 1.01
Variants in toll-like receptor 1 and 4 genes are associated with Chlamydia trachomatis among women with pelvic inflammatory disease. J Infect Dis (2012) 1.01
Porphyromonas gingivalis-nucleoside-diphosphate-kinase inhibits ATP-induced reactive-oxygen-species via P2X7 receptor/NADPH-oxidase signalling and contributes to persistence. Cell Microbiol (2013) 1.00
A Chlamydia trachomatis-specific Th2 clone does not provide protection against a genital infection and displays reduced trafficking to the infected genital mucosa. Infect Immun (2002) 0.99
Altered developmental expression of polymorphic membrane proteins in penicillin-stressed Chlamydia trachomatis. Cell Microbiol (2011) 0.99
P2X and P2Y purinergic receptors on human intestinal epithelial carcinoma cells: effects of extracellular nucleotides on apoptosis and cell proliferation. Am J Physiol Gastrointest Liver Physiol (2005) 0.97
Leptospira interrogans induces apoptosis in macrophages via caspase-8- and caspase-3-dependent pathways. Infect Immun (2008) 0.97
The combination of the gastrointestinal integrin (α4β7) and selectin ligand enhances T-Cell migration to the reproductive tract during infection with Chlamydia trachomatis. Am J Reprod Immunol (2009) 0.96
Enhanced neutrophil longevity and recruitment contribute to the severity of oviduct pathology during Chlamydia muridarum infection. Infect Immun (2011) 0.96
Infective endocarditis in Arkansan children from 1990 through 2002. Pediatr Infect Dis J (2003) 0.96
Plasmid-cured Chlamydia caviae activates TLR2-dependent signaling and retains virulence in the guinea pig model of genital tract infection. PLoS One (2012) 0.96
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia. PLoS One (2008) 0.95
Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection. PLoS One (2012) 0.95
Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein. BMC Microbiol (2008) 0.94
Differential susceptibilities to azithromycin treatment of chlamydial infection in the gastrointestinal tract and cervix. Antimicrob Agents Chemother (2013) 0.94
The danger signal adenosine induces persistence of chlamydial infection through stimulation of A2b receptors. PLoS One (2009) 0.94
The P2X(7) receptor and intracellular pathogens: a continuing struggle. Purinergic Signal (2009) 0.93
Host-Cell Survival and Death During Chlamydia Infection. Curr Immunol Rev (2007) 0.93
The mammalian cell entry (Mce) protein of pathogenic Leptospira species is responsible for RGD motif-dependent infection of cells and animals. Mol Microbiol (2012) 0.93
Correlation between infections with different genotypes of human cytomegalovirus and Epstein-Barr virus in subgingival samples and periodontal status of patients. J Clin Microbiol (2007) 0.93
Characterization of chlamydial genital infection resulting from sexual transmission from male to female guinea pigs and determination of infectious dose. Infect Immun (2003) 0.92
Impact of the gut microbiota, prebiotics, and probiotics on human health and disease. Biomed J (2014) 0.91
P2X4 assembles with P2X7 and pannexin-1 in gingival epithelial cells and modulates ATP-induced reactive oxygen species production and inflammasome activation. PLoS One (2013) 0.91
Local host response to chlamydial urethral infection in male guinea pigs. Infect Immun (2010) 0.91
Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity. Vaccine (2009) 0.90
Cell death, BAX activation, and HMGB1 release during infection with Chlamydia. Microbes Infect (2004) 0.90
Characterization of host cell death induced by Chlamydia trachomatis. Infect Immun (2006) 0.90
Essential role for neutrophils in pathogenesis and adaptive immunity in Chlamydia caviae ocular infections. Infect Immun (2011) 0.90
Transcription factor complex AP-1 mediates inflammation initiated by Chlamydia pneumoniae infection. Cell Microbiol (2012) 0.90
Tolerance of the fetus by the maternal immune system: role of inflammatory mediators at the feto-maternal interface. Reprod Biol Endocrinol (2003) 0.89
Galectin-3 is a substrate for prostate specific antigen (PSA) in human seminal plasma. Prostate (2011) 0.89
Cell death and inflammation during infection with the obligate intracellular pathogen, Chlamydia. Biochimie (2003) 0.89
Ocular pathologic response elicited by Chlamydia organisms and the predictive value of quantitative modeling. J Infect Dis (2009) 0.88
Comparison of invasion of fibroblasts and macrophages by high- and low-virulence Leptospira strains: colonization of the host-cell nucleus and induction of necrosis by the virulent strain. Arch Microbiol (2007) 0.88
Hirsutella sinensis mycelium suppresses interleukin-1β and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes. Sci Rep (2013) 0.88
Expression of purinergic receptors and modulation of P2X7 function by the inflammatory cytokine IFNgamma in human epithelial cells. Biochim Biophys Acta (2009) 0.88
Chikungunya fever--re-emergence of an old disease. Microbes Infect (2009) 0.88
Retracted InvA protein is a Nudix hydrolase required for infection by pathogenic Leptospira in cell lines and animals. J Biol Chem (2011) 0.88
Replication or death: distinct fates of pathogenic Leptospira strain Lai within macrophages of human or mouse origin. Innate Immun (2009) 0.87