Published in Mol Cell Endocrinol on July 11, 2012
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Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. Proc Natl Acad Sci U S A (2013) 1.45
AMPK and Exercise: Glucose Uptake and Insulin Sensitivity. Diabetes Metab J (2013) 1.03
Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 proteins in human skeletal muscle. J Physiol (2013) 1.02
Novel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis. Brain (2014) 0.82
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Lewis lung carcinoma regulation of mechanical stretch-induced protein synthesis in cultured myotubes. Am J Physiol Cell Physiol (2015) 0.81
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Metformin exaggerates phenylephrine-induced AMPK phosphorylation independent of CaMKKβ and attenuates contractile response in endothelium-denuded rat aorta. Biochem Pharmacol (2014) 0.79
Exercise training reverses skeletal muscle atrophy in an experimental model of VCP disease. PLoS One (2013) 0.79
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Caffeine and contraction synergistically stimulate 5'-AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle. Physiol Rep (2015) 0.78
Regulation of ion channels and transporters by AMP-activated kinase (AMPK). Channels (Austin) (2013) 0.78
Acetylation of TUG protein promotes the accumulation of GLUT4 glucose transporters in an insulin-responsive intracellular compartment. J Biol Chem (2015) 0.77
Impaired translocation of GLUT4 results in insulin resistance of atrophic soleus muscle. Biomed Res Int (2015) 0.77
Running performance at high running velocities is impaired but V'O(₂max) and peripheral endothelial function are preserved in IL-6⁻/⁻ mice. PLoS One (2014) 0.76
Features of an altered AMPK metabolic pathway in Gilbert's Syndrome, and its role in metabolic health. Sci Rep (2016) 0.76
Muscle glycogen remodeling and glycogen phosphate metabolism following exhaustive exercise of wild type and laforin knockout mice. J Biol Chem (2015) 0.76
Heat stress acutely activates insulin-independent glucose transport and 5'-AMP-activated protein kinase prior to an increase in HSP72 protein in rat skeletal muscle. Physiol Rep (2015) 0.75
Association between Indices of Body Composition and Abnormal Metabolic Phenotype in Normal-Weight Chinese Adults. Int J Environ Res Public Health (2017) 0.75
Muscle-specific loss of Bmal1 leads to disrupted tissue glucose metabolism and systemic glucose homeostasis. Skelet Muscle (2016) 0.75
Adiponectin serenades ceramidase to improve metabolism. Mol Metab (2017) 0.75
Genome-wide landscape of DNA methylomes and their relationship with mRNA and miRNA transcriptomes in oxidative and glycolytic skeletal muscles. Sci Rep (2016) 0.75
Adenosine Monophosphate (AMP)-Activated Protein Kinase: A New Target for Nutraceutical Compounds. Int J Mol Sci (2017) 0.75
Evaluation of fish oil-rich in MUFAs for anti-diabetic and anti-inflammation potential in experimental type 2 diabetic rats. Korean J Physiol Pharmacol (2016) 0.75
Fighting obesity: When muscle meets fat. Adipocyte (2014) 0.75
AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice. Sci Rep (2017) 0.75
Neuronal Nitric Oxide Synthase Mediates Insulin- and Oxidative Stress-Induced Glucose Uptake in Skeletal Muscle Myotubes. Free Radic Biol Med (2017) 0.75
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet (2009) 5.43
The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity. J Clin Invest (2003) 4.11
Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle. J Biol Chem (2003) 3.58
Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes. Diabetes (2004) 2.70
Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle. FASEB J (2005) 2.17
Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport. Appl Physiol Nutr Metab (2007) 1.89
AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits. Diabetes (2006) 1.85
The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading. Diabetes (2004) 1.75
PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle. Am J Physiol Endocrinol Metab (2007) 1.71
Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction. Am J Physiol Endocrinol Metab (2007) 1.60
Role of AMPKalpha2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle. Am J Physiol Endocrinol Metab (2006) 1.59
5'-AMP-activated protein kinase activity and protein expression are regulated by endurance training in human skeletal muscle. Am J Physiol Endocrinol Metab (2003) 1.50
Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle. Proc Natl Acad Sci U S A (2010) 1.48
Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle. Am J Physiol Endocrinol Metab (2009) 1.42
Lipid-induced insulin resistance affects women less than men and is not accompanied by inflammation or impaired proximal insulin signaling. Diabetes (2010) 1.41
5'-AMP-activated protein kinase activity and subunit expression in exercise-trained human skeletal muscle. J Appl Physiol (1985) (2002) 1.37
Effects of endurance exercise training on insulin signaling in human skeletal muscle: interactions at the level of phosphatidylinositol 3-kinase, Akt, and AS160. Diabetes (2007) 1.36
Higher skeletal muscle alpha2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise. J Physiol (2006) 1.34
AS160 phosphorylation is associated with activation of alpha2beta2gamma1- but not alpha2beta2gamma3-AMPK trimeric complex in skeletal muscle during exercise in humans. Am J Physiol Endocrinol Metab (2006) 1.33
Changes in exercise-induced gene expression in 5'-AMP-activated protein kinase gamma3-null and gamma3 R225Q transgenic mice. Diabetes (2005) 1.29
Genetic impairment of AMPKalpha2 signaling does not reduce muscle glucose uptake during treadmill exercise in mice. Am J Physiol Endocrinol Metab (2009) 1.25
Molecular mechanism by which AMP-activated protein kinase activation promotes glycogen accumulation in muscle. Diabetes (2011) 1.24
5'AMP activated protein kinase expression in human skeletal muscle: effects of strength training and type 2 diabetes. J Physiol (2005) 1.22
Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise. Am J Physiol Endocrinol Metab (2004) 1.22
Exercise-induced TBC1D1 Ser237 phosphorylation and 14-3-3 protein binding capacity in human skeletal muscle. J Physiol (2010) 1.21
PGC-1alpha mediates exercise-induced skeletal muscle VEGF expression in mice. Am J Physiol Endocrinol Metab (2009) 1.20
A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle. Am J Physiol Cell Physiol (2009) 1.19
Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise. J Physiol (2006) 1.17
Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment. Diabetes (2007) 1.16
AMPK activity and isoform protein expression are similar in muscle of obese subjects with and without type 2 diabetes. Am J Physiol Endocrinol Metab (2003) 1.15
Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes. Diabetes (2003) 1.13
PDH-E1alpha dephosphorylation and activation in human skeletal muscle during exercise: effect of intralipid infusion. Diabetes (2006) 1.12
Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle. Am J Physiol Cell Physiol (2009) 1.09
Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise. J Physiol (2004) 1.07
PGC-1alpha is required for training-induced prevention of age-associated decline in mitochondrial enzymes in mouse skeletal muscle. Exp Gerontol (2010) 1.06
Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise. Diabetes (2002) 1.05
Caffeine-induced Ca(2+) release increases AMPK-dependent glucose uptake in rodent soleus muscle. Am J Physiol Endocrinol Metab (2007) 1.05
Comment on De Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796-2809. Diabetes (2022) 1.05
Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 proteins in human skeletal muscle. J Physiol (2013) 1.02
AMPK alpha1 activation is required for stimulation of glucose uptake by twitch contraction, but not by H2O2, in mouse skeletal muscle. PLoS One (2008) 1.02
Phosphorylation-dependent translocation of glycogen synthase to a novel structure during glycogen resynthesis. J Biol Chem (2005) 1.00
Bed rest reduces metabolic protein content and abolishes exercise-induced mRNA responses in human skeletal muscle. Am J Physiol Endocrinol Metab (2011) 1.00
PGC-1{alpha} is required for AICAR-induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscle. Am J Physiol Endocrinol Metab (2010) 0.99
Role of 5'AMP-activated protein kinase in glycogen synthase activity and glucose utilization: insights from patients with McArdle's disease. J Physiol (2002) 0.99
Regulation of glycogen synthase activity and phosphorylation by exercise. Proc Nutr Soc (2004) 0.98
Exercise alleviates lipid-induced insulin resistance in human skeletal muscle-signaling interaction at the level of TBC1 domain family member 4. Diabetes (2012) 0.98
LKB1 regulates lipid oxidation during exercise independently of AMPK. Diabetes (2013) 0.98
Dual regulation of muscle glycogen synthase during exercise by activation and compartmentalization. J Biol Chem (2009) 0.97
Effect of endurance exercise training on Ca2+ calmodulin-dependent protein kinase II expression and signalling in skeletal muscle of humans. J Physiol (2007) 0.97
Can exercise mimetics substitute for exercise? Cell Metab (2008) 0.94
GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance. Diabetes (2012) 0.94
Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling. Mol Endocrinol (2008) 0.92
Oral glucose ingestion attenuates exercise-induced activation of 5'-AMP-activated protein kinase in human skeletal muscle. Biochem Biophys Res Commun (2006) 0.92
Exercise signalling to glucose transport in skeletal muscle. Proc Nutr Soc (2004) 0.91
Impact of genetic versus environmental factors on the control of muscle glycogen synthase activation in twins. Diabetes (2005) 0.91
Human muscle fibre type-specific regulation of AMPK and downstream targets by exercise. J Physiol (2015) 0.90
Impairments in site-specific AS160 phosphorylation and effects of exercise training. Diabetes (2013) 0.89
Nitric oxide production is a proximal signaling event controlling exercise-induced mRNA expression in human skeletal muscle. FASEB J (2007) 0.89
AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle. J Physiol (2013) 0.89
Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice. PLoS One (2013) 0.88
Lack of AMPKalpha2 enhances pyruvate dehydrogenase activity during exercise. Am J Physiol Endocrinol Metab (2007) 0.88
Skeletal muscle insulin signaling defects downstream of phosphatidylinositol 3-kinase at the level of Akt are associated with impaired nonoxidative glucose disposal in HIV lipodystrophy. Diabetes (2005) 0.88
Dysregulation of glycogen synthase COOH- and NH2-terminal phosphorylation by insulin in obesity and type 2 diabetes mellitus. J Clin Endocrinol Metab (2009) 0.88
Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscle. J Physiol (2007) 0.86
Na,K-ATPase activity in mouse muscle is regulated by AMPK and PGC-1α. J Membr Biol (2011) 0.86
Low muscle glycogen and elevated plasma free fatty acid modify but do not prevent exercise-induced PDH activation in human skeletal muscle. Diabetes (2009) 0.86
Impaired insulin activation and dephosphorylation of glycogen synthase in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment. J Clin Endocrinol Metab (2008) 0.86
Increased atypical PKC activity in endurance-trained human skeletal muscle. Biochem Biophys Res Commun (2003) 0.85
Higher intramuscular triacylglycerol in women does not impair insulin sensitivity and proximal insulin signaling. J Appl Physiol (1985) (2009) 0.85
Exercise-induced pyruvate dehydrogenase activation is not affected by 7 days of bed rest. J Appl Physiol (1985) (2011) 0.84
Enhanced voluntary wheel running in GPRC6A receptor knockout mice. Physiol Behav (2013) 0.84
Inhibition of lipolysis stimulates peripheral glucose uptake but has no effect on endogenous glucose production in HIV lipodystrophy. Diabetes (2007) 0.84
Regulation of PDH in human arm and leg muscles at rest and during intense exercise. Am J Physiol Endocrinol Metab (2007) 0.84
Adiponectin concentration is associated with muscle insulin sensitivity, AMPK phosphorylation, and ceramide content in skeletal muscles of men but not women. J Appl Physiol (1985) (2013) 0.83
A PGC-1α- and muscle fibre type-related decrease in markers of mitochondrial oxidative metabolism in skeletal muscle of humans with inherited insulin resistance. Diabetologia (2014) 0.83
Impaired leptin gene expression and release in cultured preadipocytes isolated from individuals born with low birth weight. Diabetes (2013) 0.83
Decreased insulin action in skeletal muscle from patients with McArdle's disease. Am J Physiol Endocrinol Metab (2002) 0.83
Effect of birth weight and 12 weeks of exercise training on exercise-induced AMPK signaling in human skeletal muscle. Am J Physiol Endocrinol Metab (2013) 0.82