Published in PLoS One on February 12, 2014
Muscle as an endocrine organ: focus on muscle-derived interleukin-6. Physiol Rev (2008) 4.87
Interleukin-6-deficient mice develop mature-onset obesity. Nat Med (2002) 4.47
Interleukin-6 and chronic inflammation. Arthritis Res Ther (2006) 3.74
AMP-activated protein kinase phosphorylation of endothelial NO synthase. FEBS Lett (1999) 3.63
Cell-cell and intracellular lactate shuttles. J Physiol (2009) 2.48
Lactate shuttles in nature. Biochem Soc Trans (2002) 2.12
Muscles and their myokines. J Exp Biol (2011) 2.07
Training-induced acceleration of O(2) uptake on-kinetics precedes muscle mitochondrial biogenesis in humans. Exp Physiol (2012) 2.00
Interleukin-6 in acute exercise and training: what is the biological relevance? Exerc Immunol Rev (2006) 1.94
AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise. Biochem Biophys Res Commun (2004) 1.75
Progressive recruitment of muscle fibers is not necessary for the slow component of VO2 kinetics. J Appl Physiol (1985) (2008) 1.71
IL-6 deficiency protects against angiotensin II induced endothelial dysfunction and hypertrophy. Arterioscler Thromb Vasc Biol (2007) 1.65
Cycling efficiency in humans is related to low UCP3 content and to type I fibres but not to mitochondrial efficiency. J Physiol (2006) 1.46
Effects of acute and chronic endurance exercise on mitochondrial uncoupling in human skeletal muscle. J Physiol (2003) 1.45
Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome. Diabetes (2006) 1.44
Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity. Am J Physiol Endocrinol Metab (2004) 1.36
Beneficial health effects of exercise--the role of IL-6 as a myokine. Trends Pharmacol Sci (2007) 1.28
Activation of AMP-activated protein kinase by interleukin-6 in rat skeletal muscle: association with changes in cAMP, energy state, and endogenous fuel mobilization. Diabetes (2009) 1.23
Exercise-induced AMPK activity in skeletal muscle: role in glucose uptake and insulin sensitivity. Mol Cell Endocrinol (2012) 1.20
Mechanisms and patterns of blood lactate increase during exercise in man. Med Sci Sports Exerc (1986) 1.18
Repeatability of exercise behaviors in mice. Physiol Behav (2009) 1.15
Acute exercise activates AMPK and eNOS in the mouse aorta. Am J Physiol Heart Circ Physiol (2011) 1.08
Reduced exercise endurance in interleukin-6-deficient mice. Endocrinology (2004) 1.07
AMP-activated protein kinase--a sensor of glycogen as well as AMP and ATP? Acta Physiol (Oxf) (2009) 1.06
Mitochondrial biogenesis and PGC-1α deacetylation by chronic treadmill exercise: differential response in cardiac and skeletal muscle. Basic Res Cardiol (2011) 0.98
Non-linear relationship between O2 uptake and power output at high intensities of exercise in humans. J Physiol (1995) 0.96
IL-6 deficiency in mice neither impairs induction of metabolic genes in the liver nor affects blood glucose levels during fasting and moderately intense exercise. Diabetologia (2010) 0.95
Interleukin-6 mediates exercise-induced increase in insulin sensitivity in mice. Exp Physiol (2012) 0.88
Changes in acid-base status of marathon runners during an incremental field test. Relationship to mean competitive marathon velocity. Eur J Appl Physiol Occup Physiol (1993) 0.86
Endurance training decreases the non-linearity in the oxygen uptake-power output relationship in humans. Exp Physiol (2011) 0.86
Single bout of endurance exercise increases NNMT activity in the liver and MNA concentration in plasma; the role of IL-6. Pharmacol Rep (2012) 0.84
Interleukin-6 release is higher across arm than leg muscles during whole-body exercise. Exp Physiol (2011) 0.83
IL-6 deficiency increases fatty acid transporters and intramuscular lipid content in red but not white skeletal muscle. J Physiol Pharmacol (2008) 0.80
A single bout of exercise increases the expression of glucose but not fatty acid transporters in skeletal muscle of IL-6 KO mice. Lipids (2012) 0.79
Training induced decrease in oxygen cost of cycling is accompanied by down-regulation of SERCA expression in human vastus lateralis muscle. J Physiol Pharmacol (2008) 0.79