Published in Invest Ophthalmol Vis Sci on August 24, 2012
Ultrastructural changes associated with dexamethasone-induced ocular hypertension in mice. Invest Ophthalmol Vis Sci (2014) 1.26
Pilocarpine-induced dilation of Schlemm's canal and prevention of lumen collapse at elevated intraocular pressures in living mice visualized by OCT. Invest Ophthalmol Vis Sci (2014) 0.98
Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction. Prog Retin Eye Res (2014) 0.93
The structure of the trabecular meshwork, its connections to the ciliary muscle, and the effect of pilocarpine on outflow facility in mice. Invest Ophthalmol Vis Sci (2014) 0.93
Role of nitric oxide in murine conventional outflow physiology. Am J Physiol Cell Physiol (2015) 0.91
The influence of genetic background on conventional outflow facility in mice. Invest Ophthalmol Vis Sci (2013) 0.90
What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease. Exp Eye Res (2013) 0.90
Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities. Exp Eye Res (2015) 0.88
ATP-sensitive potassium (K(ATP)) channel openers diazoxide and nicorandil lower intraocular pressure in vivo. Invest Ophthalmol Vis Sci (2013) 0.84
Measurement of Outflow Facility Using iPerfusion. PLoS One (2016) 0.84
Optimizing gene transfer to conventional outflow cells in living mouse eyes. Exp Eye Res (2013) 0.84
Pigment epithelium-derived factor decreases outflow facility. Invest Ophthalmol Vis Sci (2013) 0.83
Animal models of glucocorticoid-induced glaucoma. Exp Eye Res (2015) 0.82
High-throughput screening for modulators of cellular contractile force. Integr Biol (Camb) (2015) 0.82
Physical Factors Affecting Outflow Facility Measurements in Mice. Invest Ophthalmol Vis Sci (2015) 0.81
Feedback-controlled constant-pressure anterior chamber perfusion in live mice. Mol Vis (2014) 0.80
Endogenous production of extracellular adenosine by trabecular meshwork cells: potential role in outflow regulation. Invest Ophthalmol Vis Sci (2012) 0.79
Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma. J Ocul Pharmacol Ther (2013) 0.78
Visualization of conventional outflow tissue responses to netarsudil in living mouse eyes. Eur J Pharmacol (2016) 0.78
The formation of cortical actin arrays in human trabecular meshwork cells in response to cytoskeletal disruption. Exp Cell Res (2014) 0.78
Localized and Controlled Delivery of Nitric Oxide to the Conventional Outflow Pathway via Enzyme Biocatalysis: Toward Therapy for Glaucoma. Adv Mater (2017) 0.77
Differential effects of prostaglandin E2-sensitive receptors on contractility of human ocular cells that regulate conventional outflow. Invest Ophthalmol Vis Sci (2013) 0.76
Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo. Proc Natl Acad Sci U S A (2016) 0.76
System for Rapid, Precise Modulation of Intraocular Pressure, toward Minimally-Invasive In Vivo Measurement of Intracranial Pressure. PLoS One (2016) 0.76
Unconventional aqueous humor outflow: A review. Exp Eye Res (2016) 0.76
Suppression of Acid Sphingomyelinase Protects the Retina from Ischemic Injury. Invest Ophthalmol Vis Sci (2016) 0.75
ATP-sensitive potassium (KATP) channel openers diazoxide and nicorandil lower intraocular pressure by activating the Erk1/2 signaling pathway. PLoS One (2017) 0.75
The Soluble Guanylate Cyclase Stimulator IWP-953 Increases Conventional Outflow Facility in Mouse Eyes. Invest Ophthalmol Vis Sci (2016) 0.75
Dose- and time-dependent effects of actomyosin inhibition on live mouse outflow resistance and aqueous drainage tissues. Sci Rep (2016) 0.75
VEGF as a Paracrine Regulator of Conventional Outflow Facility. Invest Ophthalmol Vis Sci (2017) 0.75
Model systems for the study of steroid-induced IOP elevation. Exp Eye Res (2016) 0.75
Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol (2003) 9.29
Uveoscleral drainage of aqueous humour in human eyes. Exp Eye Res (1971) 1.79
Aqueous humor dynamics in mice. Invest Ophthalmol Vis Sci (2003) 1.73
Adenoviral gene transfer of active human transforming growth factor-{beta}2 elevates intraocular pressure and reduces outflow facility in rodent eyes. Invest Ophthalmol Vis Sci (2009) 1.56
Aquaporin deletion in mice reduces intraocular pressure and aqueous fluid production. J Gen Physiol (2002) 1.46
Reliable measurement of mouse intraocular pressure by a servo-null micropipette system. Invest Ophthalmol Vis Sci (2001) 1.45
The mechanism of increasing outflow facility during washout in the bovine eye. Invest Ophthalmol Vis Sci (2002) 1.44
Aqueous humor dynamics in the aging human eye. Am J Ophthalmol (1999) 1.44
International Union of Basic and Clinical Pharmacology. LXXXIII: classification of prostanoid receptors, updating 15 years of progress. Pharmacol Rev (2011) 1.43
eNOS, a pressure-dependent regulator of intraocular pressure. Invest Ophthalmol Vis Sci (2011) 1.38
Outflow physiology of the mouse eye: pressure dependence and washout. Invest Ophthalmol Vis Sci (2011) 1.36
Analysis of sphingosine 1-phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools. Br J Pharmacol (2007) 1.31
Absence of time-dependent facility increase ("washout") in the perfused enucleated human eye. Invest Ophthalmol Vis Sci (1990) 1.30
Role of lysophospholipid growth factors in the modulation of aqueous humor outflow facility. Invest Ophthalmol Vis Sci (2004) 1.30
Assessment of aqueous humor dynamics in the mouse by a novel method of constant-flow infusion. Invest Ophthalmol Vis Sci (2011) 1.27
Growth factor-like phospholipids generated after corneal injury. Am J Physiol (1998) 1.27
Effects of prostaglandins on the aqueous humor outflow pathways. Surv Ophthalmol (2002) 1.22
Expression and localization of FP and EP prostanoid receptor subtypes in human ocular tissues. Invest Ophthalmol Vis Sci (2002) 1.19
Enhanced inflow and outflow rates despite lower IOP in bestrophin-2-deficient mice. Invest Ophthalmol Vis Sci (2008) 1.19
Mouse genetics: a tool to help unlock the mechanisms of glaucoma. J Glaucoma (1999) 1.19
Reduction of intraocular pressure in mouse eyes treated with latanoprost. Invest Ophthalmol Vis Sci (2002) 1.17
Morphology of the aqueous outflow pathway. Microsc Res Tech (1996) 1.16
Prostaglandins increase trabecular meshwork outflow facility in cultured human anterior segments. Am J Ophthalmol (2007) 1.15
Effect of latanoprost on outflow facility in the mouse. Invest Ophthalmol Vis Sci (2004) 1.11
Goldmann's equation and clinical measures of aqueous dynamics. Exp Eye Res (2004) 1.05
Duration of anesthesia affects intraocular pressure, but not outflow facility in mice. Curr Eye Res (2010) 1.04
Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes. Exp Eye Res (2009) 1.03
Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects. Front Pharmacol (2011) 1.01
Regulation of anterior chamber drainage by bicarbonate-sensitive soluble adenylyl cyclase in the ciliary body. J Biol Chem (2011) 0.98
Outflow facility in mice with a targeted type I collagen mutation. Invest Ophthalmol Vis Sci (2009) 0.98
The role of the prostaglandin EP4 receptor in the regulation of human outflow facility. Invest Ophthalmol Vis Sci (2011) 0.98
Human trabecular meshwork organ culture: morphology and glycosaminoglycan synthesis. Invest Ophthalmol Vis Sci (1988) 0.97
Influence of temperature and the question of involvement of cellular metabolism in aqueous outflow. Am J Ophthalmol (1974) 0.95
Vascular actions of nitric oxide as affected by exposure to alcohol. Alcohol Alcohol (2010) 0.93
Expression of cyclooxygenase-1 and -2 in normal and glaucomatous human eyes. Invest Ophthalmol Vis Sci (2001) 0.93
S1P₂ receptor regulation of sphingosine-1-phosphate effects on conventional outflow physiology. Am J Physiol Cell Physiol (2011) 0.93
Selectivity and specificity of sphingosine 1-phosphate receptor ligands: "off-targets" or complex pharmacology? Front Pharmacol (2011) 0.91
Prostanoid EP4 receptor stimulation produces ocular hypotension by a mechanism that does not appear to involve uveoscleral outflow. Invest Ophthalmol Vis Sci (2009) 0.91
The regulation of neuronal gene expression by alcohol. Pharmacol Ther (2009) 0.90
Endogenous Bioactive Lipids and the Regulation of Conventional Outflow Facility. Expert Rev Ophthalmol (2008) 0.89
The sphingosine-1-phosphate receptor-1 antagonist, W146, causes early and short-lasting peripheral blood lymphopenia in mice. Int Immunopharmacol (2011) 0.88
Serum proteins and aqueous outflow resistance in bovine eyes. Invest Ophthalmol Vis Sci (1993) 0.88
Effect of latanoprost on intraocular pressure in mice lacking the prostaglandin FP receptor. Invest Ophthalmol Vis Sci (2004) 0.88
Prostaglandin E2 receptor subtypes, EP1, EP2, EP3 and EP4 in human and mouse ocular tissues--a comparative immunohistochemical study. Prostaglandins Leukot Essent Fatty Acids (2004) 0.83
Effects of prostanoid EP agonists on mouse intraocular pressure. Invest Ophthalmol Vis Sci (2008) 0.83
Design and synthesis of a highly selective EP4-receptor agonist. Part 1: 3,7-dithiaPG derivatives with high selectivity. Bioorg Med Chem Lett (2001) 0.82
Outflow characteristics of isolated anterior segments of human eyes. Invest Ophthalmol Vis Sci (1996) 0.78
Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. J Cell Sci (2006) 2.98
Factors influencing optic nerve head biomechanics. Invest Ophthalmol Vis Sci (2005) 2.81
Finite element modeling of optic nerve head biomechanics. Invest Ophthalmol Vis Sci (2004) 2.11
L-DOPA is an endogenous ligand for OA1. PLoS Biol (2008) 2.03
Effects of TGF-beta2 in perfused human eyes. Invest Ophthalmol Vis Sci (2004) 2.00
Biomechanics of the optic nerve head. Exp Eye Res (2009) 1.94
Shadow removal and contrast enhancement in optical coherence tomography images of the human optic nerve head. Invest Ophthalmol Vis Sci (2011) 1.86
The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium. Exp Eye Res (2008) 1.77
Modeling individual-specific human optic nerve head biomechanics. Part II: influence of material properties. Biomech Model Mechanobiol (2008) 1.65
Dexamethasone alters F-actin architecture and promotes cross-linked actin network formation in human trabecular meshwork tissue. Cell Motil Cytoskeleton (2005) 1.62
The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes. Exp Eye Res (2007) 1.58
Modeling individual-specific human optic nerve head biomechanics. Part I: IOP-induced deformations and influence of geometry. Biomech Model Mechanobiol (2008) 1.57
Reduction of the available area for aqueous humor outflow and increase in meshwork herniations into collector channels following acute IOP elevation in bovine eyes. Invest Ophthalmol Vis Sci (2008) 1.53
Dimensions of the human sclera: Thickness measurement and regional changes with axial length. Exp Eye Res (2009) 1.48
Finite element modeling of the human sclera: influence on optic nerve head biomechanics and connections with glaucoma. Exp Eye Res (2010) 1.47
Levels of bimatoprost acid in the aqueous humour after bimatoprost treatment of patients with cataract. Br J Ophthalmol (2006) 1.42
eNOS, a pressure-dependent regulator of intraocular pressure. Invest Ophthalmol Vis Sci (2011) 1.38
Outflow physiology of the mouse eye: pressure dependence and washout. Invest Ophthalmol Vis Sci (2011) 1.36
Comparative studies between species that do and do not exhibit the washout effect. Exp Eye Res (2006) 1.36
Quantitative mapping of scleral fiber orientation in normal rat eyes. Invest Ophthalmol Vis Sci (2011) 1.34
Hemodynamics in the mouse aortic arch as assessed by MRI, ultrasound, and numerical modeling. Am J Physiol Heart Circ Physiol (2006) 1.30
Mechanical properties of individual focal adhesions probed with a magnetic microneedle. Biochem Biophys Res Commun (2004) 1.29
3D morphometry of the human optic nerve head. Exp Eye Res (2009) 1.26
Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins. Integr Biol (Camb) (2010) 1.23
Extracellular trafficking of myocilin in human trabecular meshwork cells. J Biol Chem (2005) 1.23
Predicted extension, compression and shearing of optic nerve head tissues. Exp Eye Res (2007) 1.20
Enhanced inflow and outflow rates despite lower IOP in bestrophin-2-deficient mice. Invest Ophthalmol Vis Sci (2008) 1.19
Intimal thickness is not associated with wall shear stress patterns in the human right coronary artery. Arterioscler Thromb Vasc Biol (2004) 1.18
Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain. J Cell Biol (2005) 1.17
Morphological changes in the anterior eye segment after long-term treatment with different receptor selective prostaglandin agonists and a prostamide. Invest Ophthalmol Vis Sci (2003) 1.17
The pore density in the inner wall endothelium of Schlemm's canal of glaucomatous eyes. Invest Ophthalmol Vis Sci (2002) 1.13
Reconstruction of human optic nerve heads for finite element modeling. Technol Health Care (2005) 1.13
A numerical study of blood flow in coronary artery bypass graft side-to-side anastomoses. Ann Biomed Eng (2002) 1.12
Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells. BMC Med Genomics (2009) 1.12
Finding of endocannabinoids in human eye tissues: implications for glaucoma. Biochem Biophys Res Commun (2005) 1.11
Synthesis of prostaglandin F ethanolamide by prostaglandin F synthase and identification of Bimatoprost as a potent inhibitor of the enzyme: new enzyme assay method using LC/ESI/MS. Arch Biochem Biophys (2004) 1.09
Human Schlemm's canal cells express the endothelial adherens proteins, VE-cadherin and PECAM-1. Curr Eye Res (2002) 1.08
Effects of cardiac motion on right coronary artery hemodynamics. Ann Biomed Eng (2003) 1.08
Comparison of prostaglandin F2alpha, bimatoprost (prostamide), and butaprost (EP2 agonist) on Cyr61 and connective tissue growth factor gene expression. J Biol Chem (2003) 1.07
Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow. J Cell Physiol (2012) 1.06
Effects of scleral stiffness properties on optic nerve head biomechanics. Ann Biomed Eng (2009) 1.05
Bimatoprost, prostamide activity, and conventional drainage. Invest Ophthalmol Vis Sci (2007) 1.05
Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line. BMC Physiol (2002) 1.05
Scleral biomechanics and glaucoma--a connection? Can J Ophthalmol (2006) 1.04
Computational analysis of coupled blood-wall arterial LDL transport. J Biomech Eng (2002) 1.04
Effects of cyclic intraocular pressure on conventional outflow facility. Invest Ophthalmol Vis Sci (2008) 1.03
Specific targeting of gene expression to a subset of human trabecular meshwork cells using the chitinase 3-like 1 promoter. Invest Ophthalmol Vis Sci (2005) 1.03
Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes. Exp Eye Res (2009) 1.03
Multi-scale analysis of segmental outflow patterns in human trabecular meshwork with changing intraocular pressure. J Ocul Pharmacol Ther (2014) 1.03
Morphometric analysis of aqueous humor outflow structures with spectral-domain optical coherence tomography. Invest Ophthalmol Vis Sci (2012) 1.02
Bimatoprost: mechanism of ocular surface hyperemia associated with topical therapy. Cardiovasc Drug Rev (2005) 1.02
Bimatoprost and prostaglandin F(2 alpha) selectively stimulate intracellular calcium signaling in different cat iris sphincter cells. Exp Eye Res (2005) 1.02
Expression analysis of the matrix GLA protein and VE-cadherin gene promoters in the outflow pathway. Invest Ophthalmol Vis Sci (2004) 1.01
Ion channel function of aquaporin-1 natively expressed in choroid plexus. J Neurosci (2006) 0.99
Human trabecular meshwork cell volume regulation. Am J Physiol Cell Physiol (2002) 0.99
A model of giant vacuole dynamics in human Schlemm's canal endothelial cells. Exp Eye Res (2010) 0.98
The role of the prostaglandin EP4 receptor in the regulation of human outflow facility. Invest Ophthalmol Vis Sci (2011) 0.98
Sphingosine-1-phosphate enhancement of cortical actomyosin organization in cultured human Schlemm's canal endothelial cell monolayers. Invest Ophthalmol Vis Sci (2010) 0.97
EP1 prostanoid receptor coupling to G i/o up-regulates the expression of hypoxia-inducible factor-1 alpha through activation of a phosphoinositide-3 kinase signaling pathway. Mol Pharmacol (2010) 0.97
The prostanoid EP2 receptor agonist butaprost increases uveoscleral outflow in the cynomolgus monkey. Invest Ophthalmol Vis Sci (2006) 0.97
Differential P1-purinergic modulation of human Schlemm's canal inner-wall cells. Am J Physiol Cell Physiol (2004) 0.95
Young's modulus of elasticity of Schlemm's canal endothelial cells. Biomech Model Mechanobiol (2009) 0.95
Cyclic mechanical stress and trabecular meshwork cell contractility. Invest Ophthalmol Vis Sci (2009) 0.93
Prostaglandin F2alpha formation from prostaglandin H2 by prostaglandin F synthase (PGFS): crystal structure of PGFS containing bimatoprost. Biochemistry (2006) 0.93
Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2013) 0.93
S1P₂ receptor regulation of sphingosine-1-phosphate effects on conventional outflow physiology. Am J Physiol Cell Physiol (2011) 0.93
Regulation of myocilin-associated exosome release from human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2008) 0.93
Experimental and numerical studies of adenovirus delivery to outflow tissues of perfused human anterior segments. Invest Ophthalmol Vis Sci (2004) 0.93
Mechanisms of ATP release, the enabling step in purinergic dynamics. Cell Physiol Biochem (2011) 0.92
Drained secant modulus for human and porcine peripapillary sclera using unconfined compression testing. Exp Eye Res (2009) 0.92
A new method for selection of angular aqueous plexus cells from porcine eyes: a model for Schlemm's canal endothelium. Invest Ophthalmol Vis Sci (2010) 0.91
Anandamide-derived prostamide F2α negatively regulates adipogenesis. J Biol Chem (2013) 0.91
Actin structure in the outflow tract of normal and glaucomatous eyes. Exp Eye Res (2005) 0.91
The influence of genetic background on conventional outflow facility in mice. Invest Ophthalmol Vis Sci (2013) 0.90
Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily. J Biol Chem (2007) 0.90
Actin structure in the outflow tract of normal and glaucomatous eyes. Exp Eye Res (2007) 0.90
Effects of cardiotonic steroids on trabecular meshwork cells: search for mediator of ouabain-enhanced outflow facility. Exp Eye Res (2012) 0.89
Differential effects of trabecular meshwork stiffness on outflow facility in normal human and porcine eyes. Invest Ophthalmol Vis Sci (2012) 0.89
Endogenous Bioactive Lipids and the Regulation of Conventional Outflow Facility. Expert Rev Ophthalmol (2008) 0.89
Cellular basis for bimatoprost effects on human conventional outflow. Invest Ophthalmol Vis Sci (2010) 0.89
PGE2 differentially regulates monocyte-derived dendritic cell cytokine responses depending on receptor usage (EP2/EP4). Mol Immunol (2013) 0.88
Perfusion with the olfactomedin domain of myocilin does not affect outflow facility. Invest Ophthalmol Vis Sci (2003) 0.88
Update on the mechanism of action of bimatoprost: a review and discussion of new evidence. Surv Ophthalmol (2004) 0.87
Upregulation of orphan nuclear receptor Nur77 following PGF(2alpha), Bimatoprost, and Butaprost treatments. Essential role of a protein kinase C pathway involved in EP(2) receptor activated Nur77 gene transcription. Br J Pharmacol (2004) 0.87
New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. J Med Chem (2007) 0.86
Structural basement membrane components and corresponding integrins in Schlemm's canal endothelia. Mol Vis (2011) 0.85
Identification of a novel alternative splicing variant of RGS5 mRNA in human ocular tissues. FEBS J (2005) 0.85
The relationship between wall shear stress distributions and intimal thickening in the human abdominal aorta. Biomed Eng Online (2003) 0.84
Stimulation of chondrogenic differentiation of adult human bone marrow-derived stromal cells by a moderate-strength static magnetic field. Tissue Eng Part A (2014) 0.84
Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells. Prostaglandins Other Lipid Mediat (2010) 0.84