Published in Cell Physiol Biochem on December 16, 2011
Molecular mechanisms of ATP secretion during immunogenic cell death. Cell Death Differ (2013) 1.64
ATP secretion in the male reproductive tract: essential role of CFTR. J Physiol (2012) 1.57
Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival. Nat Cell Biol (2015) 1.51
Mechanisms of ATP release and signalling in the blood vessel wall. Cardiovasc Res (2012) 1.27
Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system. Front Physiol (2012) 1.04
The mechanism of electrically stimulated adenosine release varies by brain region. Purinergic Signal (2012) 0.94
Purinergic and muscarinic modulation of ATP release from the urothelium and its paracrine actions. Am J Physiol Renal Physiol (2013) 0.90
The properties, functions, and pathophysiology of maxi-anion channels. Pflugers Arch (2016) 0.79
Endogenous production of extracellular adenosine by trabecular meshwork cells: potential role in outflow regulation. Invest Ophthalmol Vis Sci (2012) 0.79
Distribution and functional relevance of connexins in renin-producing cells. Pflugers Arch (2012) 0.78
Connexins form functional hemichannels in porcine ciliary epithelium. Exp Eye Res (2013) 0.77
Ocular Purine Receptors as Drug Targets in the Eye. J Ocul Pharmacol Ther (2016) 0.75
Increased membrane localization of pannexin1 in human corneal synaptosomes causes enhanced stimulated ATP release in chronic diabetes mellitus. Medicine (Baltimore) (2016) 0.75
Hyperosmotic stress induces ATP release and changes in P2X7 receptor levels in human corneal and conjunctival epithelial cells. Purinergic Signal (2017) 0.75
Cell culture: complications due to mechanical release of ATP and activation of purinoceptors. Cell Tissue Res (2017) 0.75
The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Arch Ophthalmol (2002) 16.89
Number of people with glaucoma worldwide. Br J Ophthalmol (1996) 14.31
Molecular physiology of P2X receptors. Physiol Rev (2002) 13.61
The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration.The AGIS Investigators. Am J Ophthalmol (2000) 12.21
Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial. Arch Ophthalmol (2003) 8.76
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J (2006) 8.12
Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures. Collaborative Normal-Tension Glaucoma Study Group. Am J Ophthalmol (1998) 7.34
The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma. Collaborative Normal-Tension Glaucoma Study Group. Am J Ophthalmol (1998) 6.70
Molecular structure and physiological function of chloride channels. Physiol Rev (2002) 6.09
Pannexin membrane channels are mechanosensitive conduits for ATP. FEBS Lett (2004) 4.73
P2X receptors as cell-surface ATP sensors in health and disease. Nature (2006) 4.55
Pannexin 1 in erythrocytes: function without a gap. Proc Natl Acad Sci U S A (2006) 4.03
Pannexins, a family of gap junction proteins expressed in brain. Proc Natl Acad Sci U S A (2003) 3.96
Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium. FEBS Lett (2005) 3.89
Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes. J Neurochem (2005) 3.87
Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade. Biochim Biophys Acta (2008) 3.51
CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP. Cell (1995) 3.46
Pannexin-1 couples to maitotoxin- and nigericin-induced interleukin-1beta release through a dye uptake-independent pathway. J Biol Chem (2006) 3.36
Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex. FEBS Lett (2007) 3.19
Probenecid, a gout remedy, inhibits pannexin 1 channels. Am J Physiol Cell Physiol (2008) 2.79
A ubiquitous family of putative gap junction molecules. Curr Biol (2000) 2.77
Properties of a nonjunctional current expressed from a rat connexin46 cDNA in Xenopus oocytes. J Gen Physiol (1993) 2.64
Effect of matrix metalloproteinases activity on outflow in perfused human organ culture. Invest Ophthalmol Vis Sci (1998) 2.43
Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. J Pharmacol Exp Ther (2008) 2.42
Na(+)/K(+)-ATPase as a signal transducer. Eur J Biochem (2002) 2.39
CFTR-independent ATP release from epithelial cells triggered by mechanical stimuli. Am J Physiol (1997) 2.35
Functional connexin "hemichannels": a critical appraisal. Glia (2006) 2.21
The multidrug resistance (mdr1) gene product functions as an ATP channel. Proc Natl Acad Sci U S A (1993) 2.09
Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation. Proc Natl Acad Sci U S A (1996) 2.04
The Ocular Hypertension Treatment Study: topical medication delays or prevents primary open-angle glaucoma in African American individuals. Arch Ophthalmol (2004) 2.03
Connexin and pannexin mediated cell-cell communication. Neuron Glia Biol (2007) 1.86
A release mechanism for stored ATP in ocular ciliary epithelial cells. Proc Natl Acad Sci U S A (1998) 1.66
Effects of mechanical stretching on trabecular matrix metalloproteinases. Invest Ophthalmol Vis Sci (2001) 1.60
The P2X7 receptor channel pore dilates under physiological ion conditions. J Gen Physiol (2008) 1.57
Hepatocellular ATP-binding cassette protein expression enhances ATP release and autocrine regulation of cell volume. J Biol Chem (1997) 1.47
Connexins are mechanosensitive. Am J Physiol Cell Physiol (2004) 1.46
ATP release via anion channels. Purinergic Signal (2005) 1.43
Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other. J Biol Chem (2010) 1.39
Knockout of A3 adenosine receptors reduces mouse intraocular pressure. Invest Ophthalmol Vis Sci (2002) 1.37
Endogenous and exogenous cardiac glycosides and their mechanisms of action. Am J Cardiovasc Drugs (2007) 1.36
FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels. Proc Natl Acad Sci U S A (2010) 1.30
Connexin hemichannels and gap junction channels are differentially influenced by lipopolysaccharide and basic fibroblast growth factor. Mol Biol Cell (2006) 1.30
Preliminary characterization of a transformed cell strain derived from human trabecular meshwork. Curr Eye Res (1994) 1.22
Adenosine A1 receptor modulation of MMP-2 secretion by trabecular meshwork cells. Invest Ophthalmol Vis Sci (2002) 1.21
Effects of adenosine agonists on intraocular pressure and aqueous humor dynamics in cynomolgus monkeys. Exp Eye Res (1997) 1.21
Pannexin 3 regulates intracellular ATP/cAMP levels and promotes chondrocyte differentiation. J Biol Chem (2010) 1.18
Basis of chloride transport in ciliary epithelium. J Membr Biol (2004) 1.17
A(1)-, A(2A)- and A(3)-subtype adenosine receptors modulate intraocular pressure in the mouse. Br J Pharmacol (2001) 1.16
The list of potential volume-sensitive chloride currents continues to swell (and shrink). J Gen Physiol (1998) 1.14
Cellular ATP release by the cystic fibrosis transmembrane conductance regulator. Am J Physiol (1996) 1.13
Mefloquine blockade of Pannexin1 currents: resolution of a conflict. Cell Commun Adhes (2009) 1.12
Modulation of conventional outflow facility by the adenosine A1 agonist N6-cyclohexyladenosine. Invest Ophthalmol Vis Sci (2005) 1.11
Molecular identity of the outwardly rectifying, swelling-activated anion channel: time to reevaluate pICln. J Gen Physiol (1998) 1.11
Adenosine receptor activation modulates intraocular pressure in rabbits. J Pharmacol Exp Ther (1995) 1.10
A3 adenosine receptors regulate Cl- channels of nonpigmented ciliary epithelial cells. Am J Physiol (1999) 1.09
The potassium channel subunit Kvbeta3 interacts with pannexin 1 and attenuates its sensitivity to changes in redox potentials. FEBS J (2009) 1.07
Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow. J Cell Physiol (2012) 1.06
The role of ClC-3 in volume-activated chloride currents and volume regulation in bovine epithelial cells demonstrated by antisense inhibition. J Physiol (2000) 1.05
Characterization of ocular hypertension induced by adenosine agonists. Invest Ophthalmol Vis Sci (1996) 1.05
Similarity of A(3)-adenosine and swelling-activated Cl(-) channels in nonpigmented ciliary epithelial cells. Am J Physiol Cell Physiol (2000) 1.02
Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow. Am J Physiol Cell Physiol (2010) 1.02
Pannexin 3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes. J Bone Miner Res (2011) 0.99
ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytes. J Biol Chem (2002) 0.96
Genetic demonstration that the plasma membrane maxianion channel and voltage-dependent anion channels are unrelated proteins. J Biol Chem (2005) 0.95
The ICln interactome. Acta Physiol (Oxf) (2006) 0.93
Hyposmotic activation of ICl,swell in rabbit nonpigmented ciliary epithelial cells involves increased ClC-3 trafficking to the plasma membrane. Biochem Cell Biol (2004) 0.87
Swelling-activated Cl- channels support Cl- secretion by bovine ciliary epithelium. Invest Ophthalmol Vis Sci (2006) 0.87
Mechanisms linking adenosine A1 receptors and extracellular signal-regulated kinase 1/2 activation in human trabecular meshwork cells. J Pharmacol Exp Ther (2006) 0.86
Electron microprobe analysis of rabbit ciliary epithelium indicates enhanced secretion posteriorly and enhanced absorption anteriorly. Am J Physiol Cell Physiol (2007) 0.84
Cytoskeletal dependence of adenosine triphosphate release by human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 0.84
Association of intrinsic pICln with volume-activated Cl- current and volume regulation in a native epithelial cell. Am J Physiol (1999) 0.83
Inhibition of swelling-activated Cl- currents by functional anti-ClC-3 antibody in native bovine non-pigmented ciliary epithelial cells. Invest Ophthalmol Vis Sci (2005) 0.82
CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes. Nature (2013) 2.08
L-DOPA is an endogenous ligand for OA1. PLoS Biol (2008) 2.03
The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium. Exp Eye Res (2008) 1.77
Knockout of A3 adenosine receptors reduces mouse intraocular pressure. Invest Ophthalmol Vis Sci (2002) 1.37
Outflow physiology of the mouse eye: pressure dependence and washout. Invest Ophthalmol Vis Sci (2011) 1.36
Extracellular trafficking of myocilin in human trabecular meshwork cells. J Biol Chem (2005) 1.23
Enhanced inflow and outflow rates despite lower IOP in bestrophin-2-deficient mice. Invest Ophthalmol Vis Sci (2008) 1.19
The cross-species A3 adenosine-receptor antagonist MRS 1292 inhibits adenosine-triggered human nonpigmented ciliary epithelial cell fluid release and reduces mouse intraocular pressure. Curr Eye Res (2005) 1.17
Pharmacologic manipulation of conventional outflow facility in ex vivo mouse eyes. Invest Ophthalmol Vis Sci (2012) 1.17
Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells. BMC Med Genomics (2009) 1.12
Human Schlemm's canal cells express the endothelial adherens proteins, VE-cadherin and PECAM-1. Curr Eye Res (2002) 1.08
Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow. J Cell Physiol (2012) 1.06
Bimatoprost, prostamide activity, and conventional drainage. Invest Ophthalmol Vis Sci (2007) 1.05
Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line. BMC Physiol (2002) 1.05
Effects of cyclic intraocular pressure on conventional outflow facility. Invest Ophthalmol Vis Sci (2008) 1.03
Specific targeting of gene expression to a subset of human trabecular meshwork cells using the chitinase 3-like 1 promoter. Invest Ophthalmol Vis Sci (2005) 1.03
Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow. Am J Physiol Cell Physiol (2010) 1.02
Expression analysis of the matrix GLA protein and VE-cadherin gene promoters in the outflow pathway. Invest Ophthalmol Vis Sci (2004) 1.01
Ion channel function of aquaporin-1 natively expressed in choroid plexus. J Neurosci (2006) 0.99
Inhibitors of NHE-1 Na+/H+ exchange reduce mouse intraocular pressure. Invest Ophthalmol Vis Sci (2002) 0.99
Human trabecular meshwork cell volume regulation. Am J Physiol Cell Physiol (2002) 0.99
A model of giant vacuole dynamics in human Schlemm's canal endothelial cells. Exp Eye Res (2010) 0.98
The role of the prostaglandin EP4 receptor in the regulation of human outflow facility. Invest Ophthalmol Vis Sci (2011) 0.98
Sphingosine-1-phosphate enhancement of cortical actomyosin organization in cultured human Schlemm's canal endothelial cell monolayers. Invest Ophthalmol Vis Sci (2010) 0.97
Differential P1-purinergic modulation of human Schlemm's canal inner-wall cells. Am J Physiol Cell Physiol (2004) 0.95
Noninvasive intraocular pressure measurements in mice by pneumotonometry. Invest Ophthalmol Vis Sci (2005) 0.95
Cyclic mechanical stress and trabecular meshwork cell contractility. Invest Ophthalmol Vis Sci (2009) 0.93
Regulation of myocilin-associated exosome release from human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2008) 0.93
Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2013) 0.93
S1P₂ receptor regulation of sphingosine-1-phosphate effects on conventional outflow physiology. Am J Physiol Cell Physiol (2011) 0.93
Experimental and numerical studies of adenovirus delivery to outflow tissues of perfused human anterior segments. Invest Ophthalmol Vis Sci (2004) 0.93
Drained secant modulus for human and porcine peripapillary sclera using unconfined compression testing. Exp Eye Res (2009) 0.92
A new method for selection of angular aqueous plexus cells from porcine eyes: a model for Schlemm's canal endothelium. Invest Ophthalmol Vis Sci (2010) 0.91
Effects of cardiotonic steroids on trabecular meshwork cells: search for mediator of ouabain-enhanced outflow facility. Exp Eye Res (2012) 0.89
Differential effects of trabecular meshwork stiffness on outflow facility in normal human and porcine eyes. Invest Ophthalmol Vis Sci (2012) 0.89
Endogenous Bioactive Lipids and the Regulation of Conventional Outflow Facility. Expert Rev Ophthalmol (2008) 0.89
cAMP-activated maxi-Cl(-) channels in native bovine pigmented ciliary epithelial cells. Am J Physiol Cell Physiol (2004) 0.88
Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species. Exp Eye Res (2009) 0.88
Swelling-activated Cl- channels support Cl- secretion by bovine ciliary epithelium. Invest Ophthalmol Vis Sci (2006) 0.87
Depression of intraocular pressure following inactivation of connexin43 in the nonpigmented epithelium of the ciliary body. Invest Ophthalmol Vis Sci (2009) 0.85
Structural basement membrane components and corresponding integrins in Schlemm's canal endothelia. Mol Vis (2011) 0.85
Electron microprobe analysis of ouabain-exposed ciliary epithelium: PE-NPE cell couplets form the functional units. Am J Physiol Cell Physiol (2004) 0.84
Cytoskeletal dependence of adenosine triphosphate release by human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 0.84
Electron microprobe analysis of rabbit ciliary epithelium indicates enhanced secretion posteriorly and enhanced absorption anteriorly. Am J Physiol Cell Physiol (2007) 0.84
Circumferential tensile stiffness of glaucomatous trabecular meshwork. Invest Ophthalmol Vis Sci (2014) 0.83
Pigment epithelium-derived factor decreases outflow facility. Invest Ophthalmol Vis Sci (2013) 0.83
Barrier qualities of the mouse eye to topically applied drugs. Exp Eye Res (2007) 0.83
Noninvasive assessment of aqueous humor turnover in the mouse eye. Invest Ophthalmol Vis Sci (2003) 0.83
Inhibition of swelling-activated Cl- currents by functional anti-ClC-3 antibody in native bovine non-pigmented ciliary epithelial cells. Invest Ophthalmol Vis Sci (2005) 0.82
High-throughput screening for modulators of cellular contractile force. Integr Biol (Camb) (2015) 0.82
Myocilin, a component of a membrane-associated protein complex driven by a homologous Q-SNARE domain. Biochemistry (2012) 0.82
sCD44 overexpression increases intraocular pressure and aqueous outflow resistance. Mol Vis (2013) 0.81
Regulation of gap junction coupling in bovine ciliary epithelium. Am J Physiol Cell Physiol (2010) 0.81
Cell-specific differential modulation of human trabecular meshwork cells by selective adenosine receptor agonists. Exp Eye Res (2006) 0.79
Stimulation of aquaporin-mediated fluid transport by cyclic GMP in human retinal pigment epithelium in vitro. Invest Ophthalmol Vis Sci (2012) 0.79
Species variation in biology and physiology of the ciliary epithelium: similarities and differences. Exp Eye Res (2008) 0.79
Alpha-2 adrenergic receptors stimulate actin organization in developing fetal rat cardiac myocytes. Life Sci (2003) 0.79
Electron probe X-ray microanalysis of intact pathway for human aqueous humor outflow. Am J Physiol Cell Physiol (2008) 0.79
Barriers to productive transfection of trabecular meshwork cells. Mol Vis (2005) 0.78
Expression of alpha(2)-adrenergic receptor subtypes in prenatal rat spinal cord. Brain Res Dev Brain Res (2002) 0.78
Induction of angiogenic immediate early genes by activation of FP prostanoid receptors in cultured human ciliary smooth muscle cells. Curr Eye Res (2010) 0.78
The role of activated adenosine receptors in degranulation of human LAD2 mast cells. Purinergic Signal (2014) 0.77
The effect of Rho-associated kinase inhibition on the ocular penetration of timolol maleate. Invest Ophthalmol Vis Sci (2013) 0.77
Alterations in human trabecular meshwork cell homeostasis by selenium. Exp Eye Res (2005) 0.76
DIDS and the Janus-faced Na⁺-K⁺-activated ATPase. Focus on "DIDS inhibits Na-K-ATPase activity in porcine nonpigmented ciliary epithelial cells by a Src family kinase-dependent mechanism". Am J Physiol Cell Physiol (2013) 0.76
Selenium's effects on MMP-2 and TIMP-1 secretion by human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2004) 0.76
Differential effects of prostaglandin E2-sensitive receptors on contractility of human ocular cells that regulate conventional outflow. Invest Ophthalmol Vis Sci (2013) 0.76
Implications of sustained elevation in extracellular ATP in retina following chronic ocular hypertension. Invest Ophthalmol Vis Sci (2015) 0.75
Moving forward in ocular pharmacology. J Ocul Pharmacol Ther (2012) 0.75
lncRNAs, DNA Methylation, and the Pathobiology of Exfoliation Glaucoma. J Glaucoma (2017) 0.75
Thirty years of JOPT. J Ocul Pharmacol Ther (2014) 0.75
The "T" in JOPT. J Ocul Pharmacol Ther (2015) 0.75
The trabecular meshwork special double issue, inspired by the TM study club. J Ocul Pharmacol Ther (2014) 0.75