Published in PLoS One on July 10, 2012
Measuring the methylome in clinical samples: improved processing of the Infinium Human Methylation450 BeadChip Array. Epigenetics (2012) 1.30
The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes. Genome Res (2014) 1.29
Fetal DNA Methylation Associates with Early Spontaneous Preterm Birth and Gestational Age. PLoS One (2013) 1.05
Alterations to DNA methylation and expression of CXCL14 are associated with suboptimal birth outcomes. J Hum Genet (2014) 0.84
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Sonic hedgehog (SHH) signaling improves the angiogenic potential of Wharton's jelly-derived mesenchymal stem cells (WJ-MSC). Stem Cell Res Ther (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Premature birth and later insulin resistance. N Engl J Med (2004) 4.75
Epigenetic mechanisms that underpin metabolic and cardiovascular diseases. Nat Rev Endocrinol (2009) 3.25
Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes (2011) 3.18
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Hum Mol Genet (2009) 2.85
Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life. BJOG (2008) 2.74
Clinical review: The pathogenetic role of cortisol in the metabolic syndrome: a hypothesis. J Clin Endocrinol Metab (2009) 2.50
Regulation of bone development and extracellular matrix protein genes by RUNX2. Cell Tissue Res (2009) 2.41
Relation of DNA methylation of 5'-CpG island of ACSL3 to transplacental exposure to airborne polycyclic aromatic hydrocarbons and childhood asthma. PLoS One (2009) 2.38
DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet (2010) 2.33
Activation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothers. PLoS Genet (2007) 2.19
The desmosome. Cold Spring Harb Perspect Biol (2009) 1.77
Disruption of CXC motif chemokine ligand-14 in mice ameliorates obesity-induced insulin resistance. J Biol Chem (2007) 1.75
Influence of prenatal lead exposure on genomic methylation of cord blood DNA. Environ Health Perspect (2009) 1.74
Birthweight, vitamin D receptor genotype and the programming of osteoporosis. Paediatr Perinat Epidemiol (2001) 1.61
Methylation variation at IGF2 differentially methylated regions and maternal folic acid use before and during pregnancy. Epigenetics (2011) 1.60
Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells. Biochem Biophys Res Commun (1999) 1.56
Cardiovascular risk factors at age 30 following pre-term birth. Int J Epidemiol (2007) 1.55
Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity. Dev Cell (2008) 1.54
Altered gene expression and methylation of the human chromosome 11 imprinted region in small for gestational age (SGA) placentae. Dev Biol (2008) 1.51
Quantitative, high-resolution epigenetic profiling of CpG loci identifies associations with cord blood plasma homocysteine and birth weight in humans. Epigenetics (2011) 1.50
DNA methylation patterns in cord blood DNA and body size in childhood. PLoS One (2012) 1.46
Maternal inflammation, growth retardation, and preterm birth: insights into adult cardiovascular disease. Life Sci (2011) 1.44
Does birthweight predict bone mass in adulthood? A systematic review and meta-analysis. Osteoporos Int (2010) 1.44
DNA methylation of IGF2, GNASAS, INSIGF and LEP and being born small for gestational age. Epigenetics (2011) 1.33
Functional analysis of OMICs data and small molecule compounds in an integrated "knowledge-based" platform. Methods Mol Biol (2009) 1.31
Anthrax toxin receptor 2 is expressed in murine and tumor vasculature and functions in endothelial proliferation and morphogenesis. Oncogene (2009) 1.27
Life-long echoes--a critical analysis of the developmental origins of adult disease model. Biol Neonate (2004) 1.26
Neonatal DNA methylation patterns associate with gestational age. Epigenetics (2011) 1.22
Reduced placental 11beta-hydroxysteroid dehydrogenase type 2 mRNA levels in human pregnancies complicated by intrauterine growth restriction: an analysis of possible mechanisms. J Clin Endocrinol Metab (2001) 1.21
Preterm birth--a risk factor for type 2 diabetes? The Helsinki birth cohort study. Diabetes Care (2010) 1.16
Vasculogenesis and angiogenesis in the IUGR placenta. Semin Perinatol (2008) 1.15
Cardiovascular stress hyperreactivity in babies of smokers and in babies born preterm. Circulation (2008) 1.14
Developmental origins of health and disease: reducing the burden of chronic disease in the next generation. Genome Med (2010) 1.13
Interleukin-33 in asthma: how big of a role does it play? Curr Allergy Asthma Rep (2011) 1.13
Epigenetic influences in the developmental origins of osteoporosis. Osteoporos Int (2011) 1.10
Fetal origins of adult diabetes. Ann N Y Acad Sci (2010) 1.08
Interleukin-1 receptor-like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood. J Allergy Clin Immunol (2011) 1.06
Behavior disorders in extremely preterm/extremely low birth weight children in kindergarten. J Dev Behav Pediatr (2012) 1.06
The early programming of metabolic health: is epigenetic setting the missing link? Am J Clin Nutr (2011) 1.06
CXCL14 deficiency in mice attenuates obesity and inhibits feeding behavior in a novel environment. PLoS One (2010) 1.06
The identification of novel mutations in COL1A1, COL1A2, and LEPRE1 genes in Chinese patients with osteogenesis imperfecta. J Bone Miner Metab (2011) 1.06
Non-alcoholic fatty liver disease and metabolic syndrome in adolescents: pathogenetic role of genetic background and intrauterine environment. Ann Med (2011) 1.05
Hedgehog signalling in vascular development. Angiogenesis (2008) 1.04
Signaling regulation of fetoplacental angiogenesis. J Endocrinol (2011) 1.04
Microparticles carrying Sonic hedgehog favor neovascularization through the activation of nitric oxide pathway in mice. PLoS One (2010) 1.04
IL-33 activates B1 cells and exacerbates contact sensitivity. J Immunol (2011) 1.01
Fetal growth and preterm birth influence cardiovascular risk factors and arterial health in young adults: the Cardiovascular Risk in Young Finns Study. Arterioscler Thromb Vasc Biol (2011) 0.98
CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity. Biochem Biophys Res Commun (2007) 0.97
The influence of birth size on intelligence in healthy children. Pediatrics (2009) 0.97
Decreased bone mineral density in adults born with very low birth weight: a cohort study. PLoS Med (2009) 0.97
Altered placental development in undernourished rats: role of maternal glucocorticoids. Reprod Biol Endocrinol (2011) 0.92
Low gestational age associated with abnormal retinal vascularization and increased blood pressure in adult women. Pediatr Res (2002) 0.91
Preterm birth does not affect bone mineral density in young adults. Eur J Endocrinol (2010) 0.89
Indian hedgehog requires additional effectors besides Runx2 to induce osteoblast differentiation. Dev Biol (2011) 0.88
Maternal influences on the transmission of leukocyte gene expression profiles in population samples from Brisbane, Australia. PLoS One (2010) 0.88
Consequences of fetal programming for cardiovascular disease in adulthood. Microcirculation (2011) 0.87
Size at birth, gestational age and cortisol secretion in adult life: foetal programming of both hyper- and hypocortisolism? Clin Endocrinol (Oxf) (2002) 0.87
Late gestation increase in 11beta-hydroxysteroid dehydrogenase 1 expression in human fetal membranes: a novel intrauterine source of cortisol. J Clin Endocrinol Metab (2003) 0.87
Relationship between placental expression of the imprinted PHLDA2 gene, intrauterine skeletal growth and childhood bone mass. Bone (2011) 0.86
New emerging role of pitx1 transcription factor in osteoarthritis pathogenesis. Clin Orthop Relat Res (2007) 0.85
Reactive oxygen species (ROS) reduce the expression of BRAK/CXCL14 in human head and neck squamous cell carcinoma cells. Free Radic Res (2010) 0.83
Newborn umbilical cord blood DNA methylation and gene expression levels exhibit limited association with birth weight. Chem Biodivers (2012) 0.82
Genetic and epigenetic variability in the gene for IGFBP-3 (IGFBP3): correlation with serum IGFBP-3 levels and growth in short children born small for gestational age. Growth Horm IGF Res (2008) 0.82
Birth weight and gestation influence striatal morphology and motor response in normal six-year-old boys. Neuroimage (2011) 0.82
Perturbation of gene expression of the chromatin remodeling pathway in premature newborns at risk for bronchopulmonary dysplasia. Genome Biol (2007) 0.82
High-fat diet intake accelerates aging, increases expression of Hsd11b1, and promotes lipid accumulation in liver of SAMP10 mouse. Biogerontology (2011) 0.81
Ihh enhances differentiation of CFK-2 chondrocytic cells and antagonizes PTHrP-mediated activation of PKA. J Cell Sci (2002) 0.81
Association study of candidate gene polymorphisms and obesity in a young Mexican-American population from South Texas. Arch Med Res (2011) 0.81
Nitric oxide and peroxynitrite platelet levels in women with small-for-gestational-age fetuses. BJOG (2008) 0.80
Permanent implications of intrauterine growth restriction on cholesterol homeostasis. Semin Reprod Med (2011) 0.80
Relationship of 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase gene polymorphisms with metabolic syndrome and type 2 diabetes. Endocr J (2011) 0.79
Funisitis is associated with increased interleukin-10 gene expression in cord blood mononuclear cells in preterm infants ≤32 weeks of gestation. Eur J Obstet Gynecol Reprod Biol (2010) 0.79
11β-Hydroxysteroid dehydrogenase type 1 activity in short small-for-GA children and in response to GH therapy. Pediatr Res (2011) 0.79
Loss of matrilin 1 does not exacerbate the skeletal phenotype in a mouse model of multiple epiphyseal dysplasia caused by a Matn3 V194D mutation. Arthritis Rheum (2012) 0.78
Human umbilical cord expresses several vasoactive peptides involved in the local regulation of vascular tone: protein and gene expression of Orphanin, Oxytocin, ANP, eNOS and iNOS. Folia Histochem Cytobiol (2011) 0.78
Prematurity and programming: are there later metabolic sequelae? Metab Syndr Relat Disord (2006) 0.77
Genetic polymorphism of PITX1 in susceptibility to knee osteoarthritis in a Chinese Han population: a case-control study. Rheumatol Int (2010) 0.77
Production of NO and oxidative destruction of proteins in the placenta during normal pregnancy and placental insufficiency. Bull Exp Biol Med (2003) 0.76
Perinatal bone turnover in term pregnancies: the influence of intrauterine growth restriction. Bone (2007) 0.76
Intrauterine growth restriction may not suppress bone formation at term, as indicated by circulating concentrations of undercarboxylated osteocalcin and Dickkopf-1. Metabolism (2011) 0.76
Genome-wide atlas of gene expression in the adult mouse brain. Nature (2006) 28.02
Epigenetic programming by maternal behavior. Nat Neurosci (2004) 20.92
Prevalence of diabetes among men and women in China. N Engl J Med (2010) 19.98
Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature (2012) 15.91
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
An oestrogen-receptor-alpha-bound human chromatin interactome. Nature (2009) 12.16
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci (2009) 10.17
The Protein Data Bank and structural genomics. Nucleic Acids Res (2003) 8.34
The RCSB Protein Data Bank: a redesigned query system and relational database based on the mmCIF schema. Nucleic Acids Res (2005) 7.81
The distribution and query systems of the RCSB Protein Data Bank. Nucleic Acids Res (2004) 7.03
Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat Med (2009) 6.61
The RCSB PDB information portal for structural genomics. Nucleic Acids Res (2006) 6.36
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc Natl Acad Sci U S A (2006) 5.16
An outbreak of hand, foot, and mouth disease associated with subgenotype C4 of human enterovirus 71 in Shandong, China. J Clin Virol (2009) 4.62
Tools for the automatic identification and classification of RNA base pairs. Nucleic Acids Res (2003) 4.12
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J Neurosci (2005) 3.48
Deep RNA sequencing at single base-pair resolution reveals high complexity of the rice transcriptome. Genome Res (2010) 3.34
Socioeconomic status and the brain: mechanistic insights from human and animal research. Nat Rev Neurosci (2010) 3.30
Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Nature (2011) 3.19
Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes (2011) 3.18
Resistin is expressed in human macrophages and directly regulated by PPAR gamma activators. Biochem Biophys Res Commun (2003) 3.16
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ Cardiovasc Genet (2010) 3.15
Variations in maternal care in the rat as a mediating influence for the effects of environment on development. Physiol Behav (2003) 3.09
Gene dosage of the common variant 9p21 predicts severity of coronary artery disease. J Am Coll Cardiol (2010) 3.07
Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. Proc Natl Acad Sci U S A (2006) 3.07
Maternal care associated with methylation of the estrogen receptor-alpha1b promoter and estrogen receptor-alpha expression in the medial preoptic area of female offspring. Endocrinology (2006) 2.98
Dopamine release in response to a psychological stress in humans and its relationship to early life maternal care: a positron emission tomography study using [11C]raclopride. J Neurosci (2004) 2.93
Lack of ventral striatal response to positive stimuli in depressed versus normal subjects. Am J Psychiatry (2006) 2.84
Association between genetic variation of CACNA1H and childhood absence epilepsy. Ann Neurol (2003) 2.79
Potential clinical and economic consequences of noncardiac incidental findings on cardiac computed tomography. J Am Coll Cardiol (2009) 2.76
Glucocorticoid programming. Ann N Y Acad Sci (2004) 2.73
Developmental origins of non-communicable disease: implications for research and public health. Environ Health (2012) 2.65
Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors. Cancer Discov (2014) 2.64
Determinants of outcomes after head cooling for neonatal encephalopathy. Pediatrics (2007) 2.64
Ambient air pollution, birth weight and preterm birth: a systematic review and meta-analysis. Environ Res (2012) 2.63
Darbepoetin alpha for the treatment of anemia in patients with active cancer not receiving chemotherapy or radiotherapy: results of a phase III, multicenter, randomized, double-blind, placebo-controlled study. J Clin Oncol (2008) 2.60
Prevalence of cardiovascular disease risk factor in the Chinese population: the 2007-2008 China National Diabetes and Metabolic Disorders Study. Eur Heart J (2011) 2.57
Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy. Circulation (2006) 2.50
Epigenetic mechanisms and the mismatch concept of the developmental origins of health and disease. Pediatr Res (2007) 2.47
Integration of text- and data-mining using ontologies successfully selects disease gene candidates. Nucleic Acids Res (2005) 2.46
Horizontal transfer of an adaptive chimeric photoreceptor from bryophytes to ferns. Proc Natl Acad Sci U S A (2014) 2.42
Maternal care and hippocampal plasticity: evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress. J Neurosci (2008) 2.41
Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PLoS One (2008) 2.40
E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases. EMBO J (2004) 2.38
Long-term consequences of neonatal rearing on central corticotropin-releasing factor systems in adult male rat offspring. Neuropsychopharmacology (2005) 2.35
The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes. J Neurosci (2007) 2.21
Prognostic value of 64-slice cardiac computed tomography severity of coronary artery disease, coronary atherosclerosis, and left ventricular ejection fraction. J Am Coll Cardiol (2010) 2.21
Ligand Depot: a data warehouse for ligands bound to macromolecules. Bioinformatics (2004) 2.21
Failure of frontolimbic inhibitory function in the context of negative emotion in borderline personality disorder. Am J Psychiatry (2007) 2.20
The social environment and the epigenome. Environ Mol Mutagen (2008) 2.18
Epigenetics and the environmental regulation of the genome and its function. Annu Rev Psychol (2010) 2.16
Diagnostic accuracy and impact of computed tomographic coronary angiography on utilization of invasive coronary angiography. Circ Cardiovasc Imaging (2009) 2.16
Natural variations in maternal care are associated with estrogen receptor alpha expression and estrogen sensitivity in the medial preoptic area. Endocrinology (2003) 2.15
Differential glucocorticoid receptor exon 1(B), 1(C), and 1(H) expression and methylation in suicide completers with a history of childhood abuse. Biol Psychiatry (2012) 2.13
Interventions for central retinal vein occlusion: an evidence-based systematic review. Ophthalmology (2007) 2.12
Molecular evidence of persistent epidemic and evolution of subgenotype B1 coxsackievirus A16-associated hand, foot, and mouth disease in China. J Clin Microbiol (2009) 2.11
Prevalence and risk factors for diabetic retinopathy: the Singapore Malay Eye Study. Ophthalmology (2008) 2.11
Prognostic value of CT angiography in coronary bypass patients. JACC Cardiovasc Imaging (2011) 2.10
Environmental enrichment reverses the effects of maternal separation on stress reactivity. J Neurosci (2002) 2.10
Oxytocin-dopamine interactions mediate variations in maternal behavior in the rat. Endocrinology (2010) 2.09
Repetitive ischemia by coronary stenosis induces a novel window of ischemic preconditioning. Circulation (2008) 2.09
The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model. Exp Diabetes Res (2009) 2.08
FTO variants are associated with obesity in the Chinese and Malay populations in Singapore. Diabetes (2008) 2.05
Deactivation of the limbic system during acute psychosocial stress: evidence from positron emission tomography and functional magnetic resonance imaging studies. Biol Psychiatry (2007) 2.03
Retracted The ubiquitin ligase Mul1 induces mitophagy in skeletal muscle in response to muscle-wasting stimuli. Cell Metab (2012) 2.03
Neurodevelopmental sequelae of postnatal maternal care in rodents: clinical and research implications of molecular insights. J Child Psychol Psychiatry (2007) 2.00
Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis. Gastroenterology (2008) 1.99
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease. Sci Transl Med (2012) 1.99
Stress during gestation alters postpartum maternal care and the development of the offspring in a rodent model. Biol Psychiatry (2006) 1.97
A periconceptional nutritional origin for noninfectious preterm birth. Science (2003) 1.97
The locus of fixation and the foveal cone mosaic. J Vis (2005) 1.96
Developmental origins of health and disease: new insights. Basic Clin Pharmacol Toxicol (2008) 1.95
Prevalence of ideal cardiovascular health and its relationship with the 4-year cardiovascular events in a northern Chinese industrial city. Circ Cardiovasc Qual Outcomes (2012) 1.93
Dysfunction of astrocyte connexins 30 and 43 in dorsal lateral prefrontal cortex of suicide completers. Biol Psychiatry (2011) 1.92
Incremental prognostic value of cardiac computed tomography in coronary artery disease using CONFIRM: COroNary computed tomography angiography evaluation for clinical outcomes: an InteRnational Multicenter registry. Circ Cardiovasc Imaging (2011) 1.89
Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat. Front Neuroendocrinol (2005) 1.87
Broad epigenetic signature of maternal care in the brain of adult rats. PLoS One (2011) 1.86
Progesterone withdrawal and estrogen activation in human parturition are coordinated by progesterone receptor A expression in the myometrium. J Clin Endocrinol Metab (2002) 1.85
Acute effects of air pollution on pulmonary function, airway inflammation, and oxidative stress in asthmatic children. Environ Health Perspect (2008) 1.83
Bipolar resistance switching characteristics with opposite polarity of Au/SrTiO3/Ti memory cells. Nanoscale Res Lett (2011) 1.82
Plant-symbiotic fungi as chemical engineers: multi-genome analysis of the clavicipitaceae reveals dynamics of alkaloid loci. PLoS Genet (2013) 1.81
Questionable value of planting thirsty trees in dry regions. Nature (2010) 1.81
Epigenetic programming of stress responses through variations in maternal care. Ann N Y Acad Sci (2004) 1.81
Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites. Ann N Y Acad Sci (2004) 1.80
Cohort profile: Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort study. Int J Epidemiol (2013) 1.79
Developmental origins of metabolic disease: life course and intergenerational perspectives. Trends Endocrinol Metab (2010) 1.78
Transgenerational effects of social environment on variations in maternal care and behavioral response to novelty. Behav Neurosci (2007) 1.76
Variations in nucleus accumbens dopamine associated with individual differences in maternal behavior in the rat. J Neurosci (2004) 1.76
Prenatal maternal depression associates with microstructure of right amygdala in neonates at birth. Biol Psychiatry (2013) 1.75