PubRank

Marina Protopopova

Author PubWeight™ 37.49‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors. Nat Med 2004 5.48
2 High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients. Cancer Cell 2006 5.01
3 The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis. Cancer Cell 2007 3.76
4 Identification of new diamine scaffolds with activity against Mycobacterium tuberculosis. J Med Chem 2006 3.75
5 Combinatorial lead optimization of [1,2]-diamines based on ethambutol as potential antituberculosis preclinical candidates. J Comb Chem 2003 2.63
6 Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. Proc Natl Acad Sci U S A 2008 1.92
7 Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug. Br J Pharmacol 2005 1.88
8 The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans. Cancer Cell 2006 1.30
9 Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action. Future Microbiol 2012 1.27
10 Drug therapy of experimental tuberculosis (TB): improved outcome by combining SQ109, a new diamine antibiotic, with existing TB drugs. Antimicrob Agents Chemother 2007 1.24
11 Synergistic interactions of SQ109, a new ethylene diamine, with front-line antitubercular drugs in vitro. J Antimicrob Chemother 2006 1.12
12 Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis. Antimicrob Agents Chemother 2009 1.07
13 Interspecies pharmacokinetics and in vitro metabolism of SQ109. Br J Pharmacol 2006 1.01
14 Simultaneous estimation of pharmacokinetic properties in mice of three anti-tubercular ethambutol analogs obtained from combinatorial lead optimization. J Pharm Biomed Anal 2004 1.01
15 Discovery of dipiperidines as new antitubercular agents. Bioorg Med Chem Lett 2009 0.97
16 Chemical modification of capuramycins to enhance antibacterial activity. J Antimicrob Chemother 2010 0.93
17 Identification of SQ609 as a lead compound from a library of dipiperidines. Bioorg Med Chem Lett 2011 0.93
18 915 MHz microwaves and 50 Hz magnetic field affect chromatin conformation and 53BP1 foci in human lymphocytes from hypersensitive and healthy persons. Bioelectromagnetics 2005 0.90
19 EBV-encoded EBNA-5 associates with P14ARF in extranucleolar inclusions and prolongs the survival of P14ARF-expressing cells. Int J Cancer 2003 0.86
20 Therapeutic efficacy of SQ641-NE against Mycobacterium tuberculosis. Antimicrob Agents Chemother 2013 0.76