Published in Cell Mol Neurobiol on July 31, 2012
Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells. Redox Biol (2013) 0.85
Mechanisms involved in the ischemic tolerance in brain: effect of the homocysteine. Cell Mol Neurobiol (2014) 0.81
A novel oxidative stress marker in migraine patients: dynamic thiol-disulphide homeostasis. Neurol Sci (2016) 0.80
Role of Homocysteine in the Ischemic Stroke and Development of Ischemic Tolerance. Front Neurosci (2016) 0.77
Low-Dose Homocystine Enhances Proliferation and Migration of Bv2 Microglia Cells. Cell Mol Neurobiol (2016) 0.77
Neuron-astrocyte interactions in neurodegenerative diseases: Role of neuroinflammation. Clin Exp Neuroimmunol (2015) 0.76
Cysteine, Glutathione, and Thiol Redox Balance in Astrocytes. Antioxidants (Basel) (2017) 0.75
The change in serum Thiol/Disulphide homeostasis after transrectal ultrasound guided prostate biopsy. Int Braz J Urol (2017) 0.75
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem (1969) 15.62
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med (2002) 11.20
Glutathione metabolism and its selective modification. J Biol Chem (1988) 4.89
CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nat Neurosci (2001) 4.12
Metabolism and functions of glutathione in brain. Prog Neurobiol (2000) 3.74
Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2. J Biol Chem (1999) 3.41
Redox state of glutathione in human plasma. Free Radic Biol Med (2000) 2.60
Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein. Biochim Biophys Acta (2000) 2.34
Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A (1997) 2.32
Reactive nitrogen species in the chemical biology of inflammation. Arch Biochem Biophys (2004) 2.24
Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity. J Neurosci (2000) 2.21
Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione. J Neurosci (1999) 1.96
The molecular basis of the prevention of Alzheimer's disease through healthy nutrition. Exp Gerontol (2006) 1.82
The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity. Toxicology (2007) 1.73
Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture. J Biol Chem (1980) 1.71
Transport of cystine and cysteine in mammalian cells. Biochim Biophys Acta (1984) 1.61
A functional transsulfuration pathway in the brain links to glutathione homeostasis. J Biol Chem (2006) 1.61
Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress. Free Radic Biol Med (2008) 1.58
Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels. J Biol Chem (2005) 1.50
Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease. J Alzheimers Dis (2009) 1.49
Homocysteine and Alzheimer's disease. Lancet Neurol (2003) 1.33
The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures. J Neurochem (2003) 1.32
Free radicals in inflammation: second messengers and mediators of tissue destruction. Br Med Bull (1993) 1.30
The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes. J Neurochem (2006) 1.28
Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage. J Neurosci Res (2002) 1.27
Expression of the cystathionine beta synthase (CBS) gene during mouse development and immunolocalization in adult brain. J Histochem Cytochem (2003) 1.23
Maintenance of neuronal glutathione by glial cells. J Neurochem (1993) 1.23
Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer's disease? J Alzheimers Dis (2006) 1.23
Reactive astrocytes give neurons less support: implications for Alzheimer's disease. Neurobiol Aging (2010) 1.11
Involvement of glutathione peroxidase and catalase in the disposal of exogenous hydrogen peroxide by cultured astroglial cells. Brain Res (1997) 1.07
Induction of cystine transport activity in mouse peritoneal macrophages by bacterial lipopolysaccharide. Biochem J (1995) 1.02
Modulation of astrocytic metabolic phenotype by proinflammatory cytokines. Glia (2008) 1.00
Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury. Glia (2010) 0.97
Homocysteine transport by systems L, A and y+L across the microvillous plasma membrane of human placenta. J Physiol (2009) 0.97
TNF mediates the sustained activation of Nrf2 in human monocytes. J Immunol (2011) 0.96
In vitro inactivation of mammalian methionine synthase by nitric oxide. Eur J Clin Invest (1996) 0.96
The Nrf2-inducible antioxidant defense in astrocytes can be both up- and down-regulated by activated microglia:Involvement of p38 MAPK. Glia (2011) 0.95
Identification and characterization of uptake systems for cystine and cysteine in cultured astrocytes and neurons: evidence for methylmercury-targeted disruption of astrocyte transport. J Neurosci Res (2001) 0.95
Postprandial cysteine/cystine redox potential in human plasma varies with meal content of sulfur amino acids. J Nutr (2010) 0.95
The uptake of cysteine in cultured primary astrocytes and neurons. Brain Res (2001) 0.94
Homocysteine-induced changes in mRNA levels of genes coding for cytoplasmic- and endoplasmic reticulum-resident stress proteins in neuronal cell cultures. Brain Res Mol Brain Res (2000) 0.94
Brain oxidative stress: detection and mapping of anti-oxidant marker 'Glutathione' in different brain regions of healthy male/female, MCI and Alzheimer patients using non-invasive magnetic resonance spectroscopy. Biochem Biophys Res Commun (2011) 0.93
N-acetylcysteine, but not methionine or 2-oxothiazolidine-4-carboxylate, serves as cysteine donor for the synthesis of glutathione in cultured neurons derived from embryonal rat brain. Neurosci Lett (1999) 0.92
Homocysteine and Alzheimer's disease: a modifiable risk? Free Radic Biol Med (2004) 0.87
Neuron-astrocyte interactions: implications for cellular energetics and antioxidant levels. Neurotoxicology (2000) 0.87
Alzheimer's disease and total plasma aminothiols. Biol Psychiatry (2003) 0.87
Duration of expression of inducible nitric oxide synthase in glial cells. J Neurosci Res (1994) 0.81
Different preferences in the utilization of amino acids for glutathione synthesis in cultured neurons and astroglial cells derived from rat brain. Neurosci Lett (1996) 0.81
Effects of homocysteine on metabolic pathways in cultured astrocytes. Neurochem Int (2008) 0.80
Plasma aminothiol compounds, but not serum tumor necrosis factor receptor II and soluble receptor for advanced glycation end products, are related to the cognitive impairment in Alzheimer's disease and mild cognitive impairment patients. Neuroimmunomodulation (2007) 0.80
Activation of catechol-O-methyltransferase in astrocytes stimulates homocysteine synthesis and export to neurons. Glia (2005) 0.79
[Homocysteine as a cardiovascular marker and risk factor]. Clin Res Cardiol (2006) 0.78
Differential inflammatory activation of IL-6 (-/-) astrocytes. Cytokine (2005) 0.77
Cystathionine synthase in rat brain: regional and time-of-day differences and their metabolic implications. J Neurosci Res (1979) 0.77
The dynamics of cysteine, glutathione and their disulphides in astrocyte culture medium. J Biochem (2011) 0.77
U373-MG response to interleukin-1beta-induced oxidative stress. Cell Biol Toxicol (2000) 0.76
Regional distribution of glutathione peroxidase in the adult rat brain. J Neurochem (1980) 0.76
The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl- channels. J Clin Invest (2010) 2.16
Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury. Pain (2011) 1.87
The molecular basis of the prevention of Alzheimer's disease through healthy nutrition. Exp Gerontol (2006) 1.82
Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease. J Neurosci (2007) 1.77
Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease. Neurobiol Aging (2009) 1.76
Brain atrophy in type 2 diabetes: regional distribution and influence on cognition. Diabetes Care (2013) 1.71
Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication. Nucleic Acids Res (2006) 1.62
Alzheimer vaccine: amyloid-beta on trial. Bioessays (2003) 1.43
Antioxidant and anti-inflammatory activities of selected Chinese medicinal plants and their relation with antioxidant content. BMC Complement Altern Med (2012) 1.38
Activated astroglia during chronic inflammation in Alzheimer's disease--do they neglect their neurosupportive roles? Mutat Res (2009) 1.28
Antioxidant and anti-inflammatory activities of selected medicinal plants containing phenolic and flavonoid compounds. J Agric Food Chem (2011) 1.18
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease. Adv Drug Deliv Rev (2008) 1.18
Age- and stage-dependent accumulation of advanced glycation end products in intracellular deposits in normal and Alzheimer's disease brains. Cereb Cortex (2004) 1.14
Role for glyoxalase I in Alzheimer's disease. Proc Natl Acad Sci U S A (2004) 1.12
Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers. Neurobiol Aging (2006) 1.08
Aberrant expression of NOS isoforms in Alzheimer's disease is structurally related to nitrotyrosine formation. Brain Res (2002) 1.08
Protein glycation, oxidation and nitration adduct residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment. J Neurochem (2005) 1.08
Characterization of advanced glycation end products for biochemical studies: side chain modifications and fluorescence characteristics. Anal Biochem (2005) 1.08
Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability. J Neurosci (2010) 1.07
Severity of gliosis in Pick's disease and frontotemporal lobar degeneration: tau-positive glia differentiate these disorders. Brain (2003) 1.06
Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brains. Neurobiol Aging (2006) 1.05
Reactive oxygen species are second messengers of neurokinin signaling in peripheral sensory neurons. Proc Natl Acad Sci U S A (2012) 1.03
Understanding inflammatory pain: ion channels contributing to acute and chronic nociception. Pflugers Arch (2010) 1.02
Lipoic acid as a novel treatment for Alzheimer's disease and related dementias. Pharmacol Ther (2006) 1.01
Advanced glycation end products as biomarkers and gerontotoxins - A basis to explore methylglyoxal-lowering agents for Alzheimer's disease? Exp Gerontol (2010) 0.99
The repressor element 1-silencing transcription factor regulates heart-specific gene expression using multiple chromatin-modifying complexes. Mol Cell Biol (2007) 0.99
A quick, convenient and economical method for the reliable determination of methylglyoxal in millimolar concentrations: the N-acetyl-L-cysteine assay. Anal Bioanal Chem (2012) 0.98
Activated astrocytes: a therapeutic target in Alzheimer's disease? Expert Rev Neurother (2009) 0.94
The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype. J Neurochem (2006) 0.94
Signal transduction pathways in mouse microglia N-11 cells activated by advanced glycation endproducts (AGEs). J Neurochem (2003) 0.93
Effect of pseudophosphorylation and cross-linking by lipid peroxidation and advanced glycation end product precursors on tau aggregation and filament formation. J Biol Chem (2006) 0.92
Methylglyoxal, cognitive function and cerebral atrophy in older people. J Gerontol A Biol Sci Med Sci (2012) 0.92
Pick bodies in a family with presenilin-1 Alzheimer's disease. Ann Neurol (2005) 0.90
Beta-amyloid peptide potentiates inflammatory responses induced by lipopolysaccharide, interferon -gamma and 'advanced glycation endproducts' in a murine microglia cell line. Eur J Neurosci (2003) 0.90
Pathological effects of glyoxalase I inhibition in SH-SY5Y neuroblastoma cells. J Neurosci Res (2006) 0.90
Inflammation and the redox-sensitive AGE-RAGE pathway as a therapeutic target in Alzheimer's disease. Ann N Y Acad Sci (2008) 0.90
Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer's disease. Clin Chem Lab Med (2011) 0.89
Effects of plant-derived polyphenols on TNF-alpha and nitric oxide production induced by advanced glycation endproducts. Mol Nutr Food Res (2010) 0.88
Redox and nitric oxide-mediated regulation of sensory neuron ion channel function. Antioxid Redox Signal (2014) 0.88
Lessons from the AN 1792 Alzheimer vaccine: lest we forget. Neurobiol Aging (2004) 0.87
Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity. Free Radic Biol Med (2005) 0.87
Methylglyoxal, glyoxal, and their detoxification in Alzheimer's disease. Ann N Y Acad Sci (2005) 0.86
Age-dependent changes of glyoxalase I expression in human brain. Neurobiol Aging (2005) 0.85
Induced pluripotent stem cells as tools for disease modelling and drug discovery in Alzheimer's disease. J Neural Transm (Vienna) (2012) 0.85
Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells. Redox Biol (2013) 0.85
Cytoprotective properties of traditional Chinese medicinal herbal extracts in hydrogen peroxide challenged human U373 astroglia cells. Neurochem Int (2012) 0.84
Optimizing the generation of stable neuronal cell lines via pre-transfection restriction enzyme digestion of plasmid DNA. Cytotechnology (2010) 0.84
Plant-derived polyphenols attenuate lipopolysaccharide-induced nitric oxide and tumour necrosis factor production in murine microglia and macrophages. Mol Nutr Food Res (2008) 0.83
The carbonyl scavengers aminoguanidine and tenilsetam protect against the neurotoxic effects of methylglyoxal. Neurotox Res (2005) 0.83
Automated quantification of neurite outgrowth orientation distributions on patterned surfaces. J Neural Eng (2014) 0.82
Development of a high-performance liquid chromatography method for the simultaneous quantitation of glutathione and related thiols. Anal Biochem (2012) 0.81
Induction of novel cytokines and chemokines by advanced glycation endproducts determined with a cytometric bead array. Cytokine (2007) 0.81
Bacopa monnieri (L.) exerts anti-inflammatory effects on cells of the innate immune system in vitro. Food Funct (2014) 0.80
The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase. Rejuvenation Res (2011) 0.79
A versatile high throughput screening system for the simultaneous identification of anti-inflammatory and neuroprotective compounds. J Alzheimers Dis (2010) 0.79
Coffee and Maillard products activate NF-kappaB in macrophages via H2O2 production. Mol Nutr Food Res (2007) 0.79
Identification of AGE-modified proteins in SH-SY5Y and OLN-93 cells. Neurotox Res (2006) 0.78
Determination of anti-inflammatory activities of standardised preparations of plant- and mushroom-based foods. Eur J Nutr (2013) 0.78
Vitamin D2-enriched button mushroom (Agaricus bisporus) improves memory in both wild type and APPswe/PS1dE9 transgenic mice. PLoS One (2013) 0.78
Comparison of results of the CellTiter Blue, the tetrazolium (3-[4,5-dimethylthioazol-2-yl]-2,5-diphenyl tetrazolium bromide), and the lactate dehydrogenase assay applied in brain cells after exposure to advanced glycation endproducts. Toxicol In Vitro (2007) 0.78
Advanced glycation endproducts cause lipid peroxidation in the human neuronal cell line SH-SY5Y. J Alzheimers Dis (2003) 0.78
Neuroprotective therapies for Alzheimer's disease. Curr Pharm Des (2006) 0.78
Generation of hydrogen peroxide-resistant murine neuroblastoma cells: a target discovery platform for novel neuroprotective genes. J Neural Transm (Vienna) (2013) 0.77
Proenergetic effects of resveratrol in the murine neuronal cell line Neuro2a. Mol Nutr Food Res (2013) 0.77
Activation of the transcription factor Nrf2 in macrophages, Caco-2 cells and intact human gut tissue by Maillard reaction products and coffee. Amino Acids (2012) 0.77
Anti-inflammatory activity of cinnamon (C. zeylanicum and C. cassia) extracts - identification of E-cinnamaldehyde and o-methoxy cinnamaldehyde as the most potent bioactive compounds. Food Funct (2015) 0.77
Advanced glycation endproducts induce changes in glucose consumption, lactate production, and ATP levels in SH-SY5Y neuroblastoma cells by a redox-sensitive mechanism. J Cereb Blood Flow Metab (2003) 0.77
Identification of hydrogen peroxide as a major cytotoxic component in Maillard reaction mixtures and coffee. Mol Nutr Food Res (2009) 0.76
Anti-inflammatory effects of five commercially available mushroom species determined in lipopolysaccharide and interferon-γ activated murine macrophages. Food Chem (2013) 0.76
Cytotoxicity of Maillard reaction products determined with a peptide spot library. Mol Nutr Food Res (2009) 0.76
Cytotoxicity of advanced glycation endproducts in human micro- and astroglial cell lines depends on the degree of protein glycation. J Neural Transm (Vienna) (2008) 0.76
Nuclear translocation of NF-κB in intact human gut tissue upon stimulation with coffee and roasting products. Food Funct (2011) 0.76
Comment on Vicki Brower's article 'Harnessing the immune system to battle Alzheimer's' in EMBO reports, March 2002. EMBO Rep (2002) 0.75
Disulfide stress-induced aluminium toxicity: molecular insights through genome-wide screening of Saccharomyces cerevisiae. Metallomics (2013) 0.75
Identification of aluminium transport-related genes via genome-wide phenotypic screening of Saccharomyces cerevisiae. Metallomics (2014) 0.75
Delineation of the molecular mechanism for disulfide stress-induced aluminium toxicity. Biometals (2012) 0.75
Immunochemical crossreactivity of antibodies specific for "advanced glycation endproducts" with "advanced lipoxidation endproducts". Neurobiol Aging (2005) 0.75
Use of serotonergic antidepressants and St John's wort in older Australians: a population-based cohort study. Australas Psychiatry (2013) 0.75
Characterization of antibody affinities using an AGE-modified dipeptide spot library. J Immunol Methods (2002) 0.75
Evaluation of Skin Fibroblasts from Amyotrophic Lateral Sclerosis Patients for the Rapid Study of Pathological Features. Neurotox Res (2015) 0.75
Mammalian expression systems and transfection techniques. Methods Mol Biol (2013) 0.75
Two analytical methods to study the interaction of AGEs with cell surface proteins. J Biochem Biophys Methods (2005) 0.75