Published in PLoS One on July 30, 2012
The maternal-age-associated risk of congenital heart disease is modifiable. Nature (2015) 1.14
Linking diet, physical activity, cardiorespiratory fitness and obesity to serum metabolite networks: findings from a population-based study. Int J Obes (Lond) (2014) 0.89
Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer. Lipids Health Dis (2016) 0.79
First Trimester Urine and Serum Metabolomics for Prediction of Preeclampsia and Gestational Hypertension: A Prospective Screening Study. Int J Mol Sci (2015) 0.76
Modulation of the lipidomic profile due to a lipid challenge and fitness level: a postprandial study. Lipids Health Dis (2015) 0.76
Visceral adipose tissue but not subcutaneous adipose tissue is associated with urine and serum metabolites. PLoS One (2017) 0.75
Serum metabolomic response of myasthenia gravis patients to chronic prednisone treatment. PLoS One (2014) 0.75
2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens (2007) 20.09
Exercise capacity and mortality among men referred for exercise testing. N Engl J Med (2002) 14.30
Opinion: understanding 'global' systems biology: metabonomics and the continuum of metabolism. Nat Rev Drug Discov (2003) 4.46
750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma. Anal Chem (1995) 3.61
Cardiorespiratory fitness is inversely associated with the incidence of metabolic syndrome: a prospective study of men and women. Circulation (2005) 3.27
Metabolomic identification of novel biomarkers of myocardial ischemia. Circulation (2005) 3.16
Choline and human nutrition. Annu Rev Nutr (1994) 3.09
High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism. Analyst (2009) 2.49
High intensity aerobic interval exercise is superior to moderate intensity exercise for increasing aerobic capacity in patients with coronary artery disease. Eur J Cardiovasc Prev Rehabil (2004) 2.48
Prevalence and cardiovascular disease correlates of low cardiorespiratory fitness in adolescents and adults. JAMA (2005) 2.47
Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury. J Clin Invest (2008) 2.46
Reliability and validity of self-reported physical activity in the Nord-Trøndelag Health Study: HUNT 1. Scand J Public Health (2008) 2.03
Prediction of long-term prognosis in 12 169 men referred for cardiac rehabilitation. Circulation (2002) 1.96
Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury. J Physiol (2009) 1.95
High-throughput 1H NMR-based metabolic analysis of human serum and urine for large-scale epidemiological studies: validation study. Int J Epidemiol (2008) 1.39
Divergent associations of plasma choline and betaine with components of metabolic syndrome in middle age and elderly men and women. J Nutr (2008) 1.37
Cardiovascular fitness as a predictor of mortality in men. Arch Intern Med (2001) 1.32
Metabolically healthy but obese individuals: relationship with hepatic enzymes. Metabolism (2009) 1.32
Fatty-acid composition of serum lipids predicts myocardial infarction. Br Med J (Clin Res Ed) (1982) 1.30
Whole blood choline and plasma choline in acute coronary syndromes: prognostic and pathophysiological implications. Clin Chim Acta (2007) 1.18
Serum gamma-glutamyltransferase within its normal concentration range is related to the presence of diabetes and cardiovascular risk factors. Diabet Med (2005) 1.16
Metabolomics. Cell Metab (2007) 1.09
Physical fitness matters more than physical activity in controlling cardiovascular disease risk factors. Eur J Cardiovasc Prev Rehabil (2009) 1.07
Respiratory fitness, free living physical activity, and cardiovascular disease risk in older individuals: a doubly labeled water study. J Clin Endocrinol Metab (2000) 1.02
Prevalence of the metabolic syndrome across cardiorespiratory fitness levels in women. Obes Res (2004) 1.02
Oxidative stress and redox regulation of phospholipase D in myocardial disease. Free Radic Biol Med (2006) 0.98
Nuclear magnetic resonance-based metabolomics predicts exercise-induced ischemia in patients with suspected coronary artery disease. Magn Reson Med (2008) 0.95
Association of cardiorespiratory fitness and levels of C-reactive protein: data from the National Health and Nutrition Examination Survey 1999-2002. Int J Cardiol (2006) 0.94
Choline in acute coronary syndrome: an emerging biomarker with implications for the integrated assessment of plaque vulnerability. Expert Rev Mol Diagn (2010) 0.92
Physical activity as a long-term predictor of peak oxygen uptake: the HUNT Study. Med Sci Sports Exerc (2011) 0.91
Prognostic implications of elevated whole blood choline levels in acute coronary syndromes. Am J Cardiol (2003) 0.90
Ambulatory gas exchange measurements--current status and future options. Int J Sports Med (2005) 0.89
Metabolic syndrome status changes with fitness level change: a retrospective analysis. Metab Syndr Relat Disord (2008) 0.84
Relationships of cardiorespiratory fitness with metabolic risk factors, inflammation, and liver transaminases in overweight youths. Int J Pediatr (2010) 0.83
Phosphatidic acid: a potential signal transducer for cardiac hypertrophy. J Mol Cell Cardiol (1997) 0.82
Plasma free, phospholipid-bound and urinary free choline all decrease during a marathon run and may be associated with impaired performance. J Am Coll Nutr (1999) 0.80
Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome: a pilot study. Circulation (2008) 4.61
Cardiovascular risk of high- versus moderate-intensity aerobic exercise in coronary heart disease patients. Circulation (2012) 3.92
Physiology of soccer: an update. Sports Med (2005) 2.75
Aerobic interval training reduces cardiovascular risk factors more than a multitreatment approach in overweight adolescents. Clin Sci (Lond) (2009) 2.28
High-resolution magic angle spinning MRS of breast cancer tissue. NMR Biomed (2002) 2.05
Comparison of HR MAS MR spectroscopic profiles of breast cancer tissue with clinical parameters. NMR Biomed (2006) 2.01
Temporal changes in resting heart rate and deaths from ischemic heart disease. JAMA (2011) 1.94
Effect of 2 soccer matches in a week on physical performance and injury rate. Am J Sports Med (2010) 1.85
Endothelial dysfunction induced by post-prandial lipemia: complete protection afforded by high-intensity aerobic interval exercise. J Am Coll Cardiol (2009) 1.83
Relationship between anthropometric and physiological characteristics in youth soccer players. J Strength Cond Res (2009) 1.71
Evaluation of lactate and alanine as metabolic biomarkers of prostate cancer using 1H HR-MAS spectroscopy of biopsy tissues. Magn Reson Med (2008) 1.69
Evidence against a beneficial effect of irisin in humans. PLoS One (2013) 1.68
Triple-negative breast cancer: present challenges and new perspectives. Mol Oncol (2010) 1.63
Gene expression profiling of skeletal muscle in exercise-trained and sedentary rats with inborn high and low VO2max. Physiol Genomics (2008) 1.54
High-intensity knee extensor training restores skeletal muscle function in COPD patients. Eur Respir J (2012) 1.50
Multivariate modeling and prediction of breast cancer prognostic factors using MR metabolomics. J Proteome Res (2010) 1.48
Remote ischemic preconditioning preserves mitochondrial function and influences myocardial microRNA expression in atrial myocardium during coronary bypass surgery. Circ Res (2013) 1.48
Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models. BMC Cancer (2010) 1.46
Both aerobic endurance and strength training programmes improve cardiovascular health in obese adults. Clin Sci (Lond) (2008) 1.44
Merging transcriptomics and metabolomics--advances in breast cancer profiling. BMC Cancer (2010) 1.41
Role of RyR2 phosphorylation at S2814 during heart failure progression. Circ Res (2012) 1.41
Magnetic resonance metabolomics of intact tissue: a biotechnological tool in cancer diagnostics and treatment evaluation. Cancer Res (2010) 1.40
Technical performance during soccer matches of the Italian Serie A league: effect of fatigue and competitive level. J Sci Med Sport (2008) 1.40
Aerobic interval training vs. continuous moderate exercise in the metabolic syndrome of rats artificially selected for low aerobic capacity. Cardiovasc Res (2008) 1.37
Aerobic interval training versus continuous moderate exercise after coronary artery bypass surgery: a randomized study of cardiovascular effects and quality of life. Am Heart J (2009) 1.37
Intrinsic aerobic capacity sets a divide for aging and longevity. Circ Res (2011) 1.33
Peak oxygen uptake and cardiovascular risk factors in 4631 healthy women and men. Med Sci Sports Exerc (2011) 1.32
Moderate vs. high exercise intensity: differential effects on aerobic fitness, cardiomyocyte contractility, and endothelial function. Cardiovasc Res (2005) 1.30
Interval training normalizes cardiomyocyte function, diastolic Ca2+ control, and SR Ca2+ release synchronicity in a mouse model of diabetic cardiomyopathy. Circ Res (2009) 1.29
Strength training versus aerobic interval training to modify risk factors of metabolic syndrome. J Appl Physiol (1985) (2010) 1.26
Quantification of metabolites in breast cancer patients with different clinical prognosis using HR MAS MR spectroscopy. NMR Biomed (2010) 1.26
Intensity-controlled treadmill running in mice: cardiac and skeletal muscle hypertrophy. J Appl Physiol (1985) (2002) 1.26
MR-determined metabolic phenotype of breast cancer in prediction of lymphatic spread, grade, and hormone status. Breast Cancer Res Treat (2006) 1.25
Predicting long-term survival and treatment response in breast cancer patients receiving neoadjuvant chemotherapy by MR metabolic profiling. NMR Biomed (2011) 1.24
Aerobic capacity reference data in 3816 healthy men and women 20-90 years. PLoS One (2013) 1.23
Running speed and maximal oxygen uptake in rats and mice: practical implications for exercise training. Eur J Cardiovasc Prev Rehabil (2007) 1.22
Circulating microRNAs and aerobic fitness--the HUNT-Study. PLoS One (2013) 1.20
Predicting survival and early clinical response to primary chemotherapy for patients with locally advanced breast cancer using DCE-MRI. J Magn Reson Imaging (2009) 1.19
Time-course of endothelial adaptation following acute and regular exercise. Eur J Cardiovasc Prev Rehabil (2006) 1.14
A rat model system to study complex disease risks, fitness, aging, and longevity. Trends Cardiovasc Med (2012) 1.11
Aerobic exercise before diving reduces venous gas bubble formation in humans. J Physiol (2004) 1.10
Spermine and citrate as metabolic biomarkers for assessing prostate cancer aggressiveness. PLoS One (2013) 1.09
Aerobic capacity-dependent differences in cardiac gene expression. Physiol Genomics (2008) 1.08
Aerobic interval training enhances cardiomyocyte contractility and Ca2+ cycling by phosphorylation of CaMKII and Thr-17 of phospholamban. J Mol Cell Cardiol (2007) 1.08
Comparing cardiorespiratory fitness across populations. Chest (2014) 1.07
Benefit of Exercise in Atrial Fibrillation: Diastolic Function Matters! J Am Coll Cardiol (2016) 1.06
Assessment of early docetaxel response in an experimental model of human breast cancer using DCE-MRI, ex vivo HR MAS, and in vivo 1H MRS. NMR Biomed (2010) 1.06
Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy. BMC Cancer (2012) 1.05
The effects of acute oral antioxidants on diving-induced alterations in human cardiovascular function. J Physiol (2006) 1.05
Diffusion-weighted and dynamic contrast-enhanced MRI in evaluation of early treatment effects during neoadjuvant chemotherapy in breast cancer patients. J Magn Reson Imaging (2011) 1.04
Heart failure with preserved ejection fraction induces molecular, mitochondrial, histological, and functional alterations in rat respiratory and limb skeletal muscle. Eur J Heart Fail (2015) 1.03
MRS and MRSI guidance in molecular medicine: targeting and monitoring of choline and glucose metabolism in cancer. NMR Biomed (2011) 1.03
Age and gender differences of endothelial function in 4739 healthy adults: the HUNT3 Fitness Study. Eur J Prev Cardiol (2012) 1.03
High- versus moderate-intensity aerobic exercise training effects on skeletal muscle of infarcted rats. J Appl Physiol (1985) (2013) 1.02
Short echo time 1H MRSI of the human brain at 3T with adiabatic slice-selective refocusing pulses; reproducibility and variance in a dual center setting. J Magn Reson Imaging (2010) 1.02
Low-molecular contrast agent dynamic contrast-enhanced (DCE)-MRI and diffusion-weighted (DW)-MRI in early assessment of bevacizumab treatment in breast cancer xenografts. J Magn Reson Imaging (2013) 1.02
Endothelial function in highly endurance-trained men: effects of acute exercise. J Strength Cond Res (2008) 1.02
Low- and high-volume of intensive endurance training significantly improves maximal oxygen uptake after 10-weeks of training in healthy men. PLoS One (2013) 1.01
Nitric oxide synthase type-1 modulates cardiomyocyte contractility and calcium handling: association with low intrinsic aerobic capacity. Eur J Cardiovasc Prev Rehabil (2007) 1.01
Cervical cancer tissue characterized by high-resolution magic angle spinning MR spectroscopy. MAGMA (2004) 1.00
Estimating V·O 2peak from a nonexercise prediction model: the HUNT Study, Norway. Med Sci Sports Exerc (2011) 1.00
Caloric restriction reverses hepatic insulin resistance and steatosis in rats with low aerobic capacity. Endocrinology (2010) 1.00
Effects of preterm birth and fetal growth retardation on cardiovascular risk factors in young adulthood. Early Hum Dev (2008) 0.99
Aerobic interval training increases peak oxygen uptake more than usual care exercise training in myocardial infarction patients: a randomized controlled study. Clin Rehabil (2011) 0.99
Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer. NMR Biomed (2012) 0.99
Discrimination of patients with microsatellite instability colon cancer using 1H HR MAS MR spectroscopy and chemometric analysis. J Proteome Res (2010) 0.98
Metabolic mapping by use of high-resolution magic angle spinning 1H MR spectroscopy for assessment of apoptosis in cervical carcinomas. BMC Cancer (2007) 0.98
Exercise training prevents oxidative stress and ubiquitin-proteasome system overactivity and reverse skeletal muscle atrophy in heart failure. PLoS One (2012) 0.98
Aerobic fitness is associated with cardiomyocyte contractile capacity and endothelial function in exercise training and detraining. Circulation (2004) 0.97
High-intensity interval exercise effectively improves cardiac function in patients with type 2 diabetes mellitus and diastolic dysfunction: a randomized controlled trial. J Am Coll Cardiol (2014) 0.97
A simple nonexercise model of cardiorespiratory fitness predicts long-term mortality. Med Sci Sports Exerc (2014) 0.97
Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer. Breast Cancer Res (2013) 0.95
Telomere length and long-term endurance exercise: does exercise training affect biological age? A pilot study. PLoS One (2012) 0.95
Peripheral zone prostate cancer localization by multiparametric magnetic resonance at 3 T: unbiased cancer identification by matching to histopathology. Invest Radiol (2012) 0.94
Metabolic characterization of triple negative breast cancer. BMC Cancer (2014) 0.94
Insomnia symptoms and cardiorespiratory fitness in healthy individuals: the Nord-Trøndelag Health Study (HUNT). Sleep (2013) 0.93
Lactate and glycine-potential MR biomarkers of prognosis in estrogen receptor-positive breast cancers. NMR Biomed (2012) 0.93
Dietary nitrate does not enhance running performance in elite cross-country skiers. Med Sci Sports Exerc (2012) 0.93
Effect of match-related fatigue on short-passing ability in young soccer players. Med Sci Sports Exerc (2008) 0.92
Characterization of brain metastases using high-resolution magic angle spinning MRS. NMR Biomed (2008) 0.92
Physical activity as a long-term predictor of peak oxygen uptake: the HUNT Study. Med Sci Sports Exerc (2011) 0.91
Interplay of choline metabolites and genes in patient-derived breast cancer xenografts. Breast Cancer Res (2014) 0.91