PubRank

Nick Patterson

Author PubWeight™ 536.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A second generation human haplotype map of over 3.1 million SNPs. Nature 2007 85.39
2 PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 2003 53.59
3 Large-scale copy number polymorphism in the human genome. Science 2004 34.64
4 Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 2003 29.16
5 Genome-wide detection and characterization of positive selection in human populations. Nature 2007 17.27
6 Assessing the impact of population stratification on genetic association studies. Nat Genet 2004 16.28
7 Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet 2007 14.37
8 A comparison of phasing algorithms for trios and unrelated individuals. Am J Hum Genet 2006 12.45
9 Genetic signatures of strong recent positive selection at the lactase gene. Am J Hum Genet 2004 11.90
10 A high-density admixture map for disease gene discovery in african americans. Am J Hum Genet 2004 10.87
11 Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men. Proc Natl Acad Sci U S A 2006 10.32
12 A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer. Cell 2003 9.81
13 MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nat Genet 2008 9.50
14 Reconstructing Indian population history. Nature 2009 9.28
15 Complete Khoisan and Bantu genomes from southern Africa. Nature 2010 9.06
16 Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature 2010 8.99
17 New approaches to population stratification in genome-wide association studies. Nat Rev Genet 2010 7.97
18 A high-coverage genome sequence from an archaic Denisovan individual. Science 2012 7.89
19 Discerning the ancestry of European Americans in genetic association studies. PLoS Genet 2007 7.81
20 Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One 2008 7.16
21 Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 2003 6.77
22 Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans. Nat Genet 2007 6.63
23 Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proc Natl Acad Sci U S A 2004 6.53
24 Sensitive detection of chromosomal segments of distinct ancestry in admixed populations. PLoS Genet 2009 6.36
25 Efficient mapping of mendelian traits in dogs through genome-wide association. Nat Genet 2007 5.99
26 A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility. Nat Genet 2005 5.02
27 A genomewide admixture map for Latino populations. Am J Hum Genet 2007 4.71
28 Sequencing the nuclear genome of the extinct woolly mammoth. Nature 2008 4.31
29 Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene. PLoS Genet 2009 3.60
30 Testing for ancient admixture between closely related populations. Mol Biol Evol 2011 3.56
31 Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania. Am J Hum Genet 2011 3.53
32 Reconstructing Native American population history. Nature 2012 3.49
33 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet 2011 3.07
34 The landscape of recombination in African Americans. Nature 2011 3.06
35 Long-range LD can confound genome scans in admixed populations. Am J Hum Genet 2008 3.06
36 Admixture mapping of an allele affecting interleukin 6 soluble receptor and interleukin 6 levels. Am J Hum Genet 2007 2.91
37 The history of African gene flow into Southern Europeans, Levantines, and Jews. PLoS Genet 2011 2.81
38 A common MYBPC3 (cardiac myosin binding protein C) variant associated with cardiomyopathies in South Asia. Nat Genet 2009 2.67
39 Inferring admixture histories of human populations using linkage disequilibrium. Genetics 2013 2.51
40 Extremely low-coverage sequencing and imputation increases power for genome-wide association studies. Nat Genet 2012 2.50
41 The bonobo genome compared with the chimpanzee and human genomes. Nature 2012 2.49
42 Phasing of many thousands of genotyped samples. Am J Hum Genet 2012 2.47
43 A direct characterization of human mutation based on microsatellites. Nat Genet 2012 2.38
44 The role of the CD58 locus in multiple sclerosis. Proc Natl Acad Sci U S A 2009 2.38
45 The date of interbreeding between Neandertals and modern humans. PLoS Genet 2012 2.35
46 Principal component analysis of genetic data. Nat Genet 2008 2.33
47 An integrated haplotype map of the human major histocompatibility complex. Am J Hum Genet 2003 2.29
48 Accelerated genetic drift on chromosome X during the human dispersal out of Africa. Nat Genet 2008 2.22
49 Methods in comparative genomics: genome correspondence, gene identification and regulatory motif discovery. J Comput Biol 2004 2.20
50 Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. PLoS Genet 2013 2.19
51 Will admixture mapping work to find disease genes? Philos Trans R Soc Lond B Biol Sci 2005 2.14
52 The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture. Arthritis Rheum 2008 2.13
53 Effects of cis and trans genetic ancestry on gene expression in African Americans. PLoS Genet 2008 2.09
54 Population differentiation as a test for selective sweeps. Genome Res 2010 2.08
55 Genetic structure of chimpanzee populations. PLoS Genet 2007 2.02
56 Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil). Proc Natl Acad Sci U S A 2011 1.99
57 Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet 2011 1.94
58 The case for selection at CCR5-Delta32. PLoS Biol 2005 1.83
59 Can one learn history from the allelic spectrum? Theor Popul Biol 2008 1.81
60 Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X. PLoS Genet 2009 1.81
61 Ancient west Eurasian ancestry in southern and eastern Africa. Proc Natl Acad Sci U S A 2014 1.79
62 The genetic prehistory of southern Africa. Nat Commun 2012 1.78
63 Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. PLoS Genet 2009 1.75
64 Genetic evidence for recent population mixture in India. Am J Hum Genet 2013 1.73
65 Estimating and interpreting FST: the impact of rare variants. Genome Res 2013 1.73
66 Relationship of stereochemical and skeletal diversity of small molecules to cellular measurement space. J Am Chem Soc 2004 1.59
67 Informed conditioning on clinical covariates increases power in case-control association studies. PLoS Genet 2012 1.57
68 Microsatellites are molecular clocks that support accurate inferences about history. Mol Biol Evol 2009 1.48
69 A high-density admixture scan in 1,670 African Americans with hypertension. PLoS Genet 2007 1.47
70 Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants. Am J Hum Genet 2007 1.39
71 Natural selection in a bangladeshi population from the cholera-endemic ganges river delta. Sci Transl Med 2013 1.39
72 Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection. Am J Hum Genet 2011 1.35
73 Efficient moment-based inference of admixture parameters and sources of gene flow. Mol Biol Evol 2013 1.26
74 Analysis of case-control association studies with known risk variants. Bioinformatics 2012 1.20
75 Genome-wide diversity in the levant reveals recent structuring by culture. PLoS Genet 2013 1.20
76 Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study. Obesity (Silver Spring) 2009 1.17
77 African ancestry and genetic risk for uterine leiomyomata. Am J Epidemiol 2012 1.14
78 African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts. PLoS One 2012 1.12
79 Ancestry informative marker panels for African Americans based on subsets of commercially available SNP arrays. Genet Epidemiol 2011 1.12
80 Genomic insights into the origin of farming in the ancient Near East. Nature 2016 1.07
81 Indian Siddis: African descendants with Indian admixture. Am J Hum Genet 2011 1.03
82 Reconstructing Roma history from genome-wide data. PLoS One 2013 0.96
83 Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans. PLoS One 2011 0.94
84 Admixture mapping scans identify a locus affecting retinal vascular caliber in hypertensive African Americans: the Atherosclerosis Risk in Communities (ARIC) study. PLoS Genet 2010 0.91
85 The Kalash Genetic Isolate? The Evidence for Recent Admixture. Am J Hum Genet 2016 0.89
86 Response to Sul and Eskin. Nat Rev Genet 2013 0.86
87 Combinatorics and next-generation sequencing. Nat Biotechnol 2009 0.85
88 A novel approach to estimating heterozygosity from low-coverage genome sequence. Genetics 2013 0.80
89 No bias in linkage analysis. Am J Hum Genet 2004 0.77