Nuclear factor κB activity correlates with the progression and prognosis of pancreatic cancer in a mouse model.

PubWeight™: 0.81‹?›

🔗 View Article (PMID 22892758)

Published in Surg Today on August 15, 2012

Authors

Kenei Furukawa1, Tadashi Uwagawa, Koichiro Haruki, Yuki Fujiwara, Tomonori Iida, Hiroaki Shiba, Takeyuki Misawa, Toya Ohashi, Katsuhiko Yanaga

Author Affiliations

1: Department of Surgery, Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan. k-furukawa@jikei.ac.jp

Articles cited by this

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol (1997) 29.02

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science (1996) 13.87

NF-kappaB at the crossroads of life and death. Nat Immunol (2002) 12.98

Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science (1996) 12.23

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science (1998) 11.70

Resected adenocarcinoma of the pancreas-616 patients: results, outcomes, and prognostic indicators. J Gastrointest Surg (2001) 8.34

Phase II trial of curcumin in patients with advanced pancreatic cancer. Clin Cancer Res (2008) 4.29

Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297. J Clin Oncol (2002) 4.15

The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin Cancer Res (1999) 3.36

Prognostic factors following curative resection for pancreatic adenocarcinoma: a population-based, linked database analysis of 396 patients. Ann Surg (2003) 3.13

Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death. Oncogene (2003) 2.96

The National Cancer Data Base report on pancreatic cancer. Cancer (1995) 2.77

Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene (2001) 2.71

A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform. Virchows Arch (2003) 2.53

Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice. Clin Cancer Res (2005) 2.46

Function of nuclear factor kappaB in pancreatic cancer metastasis. Clin Cancer Res (2003) 2.11

Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8. Cancer Res (2000) 1.98

Prognostic significance of activated Akt expression in pancreatic ductal adenocarcinoma. Clin Cancer Res (2004) 1.75

New insights into the role of nuclear factor-kappaB in cell growth regulation. Am J Pathol (2001) 1.69

Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis. Oncogene (2003) 1.61

Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin. Oncogene (2001) 1.46

Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic. Clin Cancer Res (1999) 1.45

High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis. Br J Cancer (2007) 1.37

Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA. Oncogene (1999) 1.15

Targeting of nuclear factor kappaB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo. Clin Cancer Res (2005) 1.09

Suppression of hormone-refractory prostate cancer by a novel nuclear factor kappaB inhibitor in nude mice. Cancer Res (2003) 1.08

Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer. Pancreas (2002) 1.07

Molecular regulation of constitutive expression of interleukin-8 in human pancreatic adenocarcinoma. J Interferon Cytokine Res (2000) 1.05

Association of p53 gene mutations with short survival in pancreatic adenocarcinoma. Jpn J Cancer Res (1995) 1.00

Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death. Cancer (2007) 0.88

A phase I study of full-dose gemcitabine and regional arterial infusion of nafamostat mesilate for advanced pancreatic cancer. Ann Oncol (2008) 0.85

Anti-tumor effect by inhibition of NF-kappaB activation using nafamostat mesilate for pancreatic cancer in a mouse model. Oncol Rep (2010) 0.85

Nafamostat mesilate can prevent adhesion, invasion and peritoneal dissemination of pancreatic cancer thorough nuclear factor kappa-B inhibition. J Hepatobiliary Pancreat Sci (2011) 0.84

A protocol for immunoaffinity separation of the accumulated ubiquitin-protein conjugates solubilized with sodium dodecyl sulfate. Anal Biochem (2008) 0.81

Articles by these authors

Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08

Prognostic factors for the late onset Pompe disease with enzyme replacement therapy: from our experience of 4 cases including an autopsy case. Mol Genet Metab (2010) 2.23

NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity. Mol Cell Biol (2004) 1.96

Laparoscopic total gastrectomy with D2 lymph node dissection for gastric cancer. Arch Surg (2009) 1.80

Placement of a metallic stent across the main duodenal papilla may predispose to cholangitis. Gastrointest Endosc (2006) 1.69

Negative impact of blood transfusion on recurrence and prognosis of hepatocellular carcinoma after hepatic resection. J Gastrointest Surg (2009) 1.69

Clinical significance of TROP2 expression in colorectal cancer. Clin Cancer Res (2006) 1.61

Donor complications associated with living donor liver transplantation in Japan. Transplantation (2009) 1.60

Generation of a transplantable erythropoietin-producer derived from human mesenchymal stem cells. Transplantation (2008) 1.58

Outcomes of living donor liver transplantation for hepatitis C virus-positive recipients in Japan: results of a nationwide survey. Transpl Int (2014) 1.49

Human mesenchymal stem cells in rodent whole-embryo culture are reprogrammed to contribute to kidney tissues. Proc Natl Acad Sci U S A (2005) 1.48

CSF-1 receptor-mediated differentiation of a new type of monocytic cell with B cell-stimulating activity: its selective dependence on IL-34. J Leukoc Biol (2013) 1.47

Successful pregnancy and lactation outcome in a patient with Gaucher disease receiving enzyme replacement therapy, and the subsequent distribution and excretion of imiglucerase in human breast milk. Clin Ther (2010) 1.43

Changes in serum levels of hepatocyte growth factor in patients undergoing adult-to-adult living-donor liver transplantation. Transplantation (2003) 1.40

Laparoscopic versus open D2 gastrectomy for advanced gastric cancer: a retrospective cohort study. Surg Endosc (2012) 1.36

Plasma globotriaosylsphingosine as a biomarker of Fabry disease. Mol Genet Metab (2010) 1.31

Long-term efficacy of hematopoietic stem cell transplantation on brain involvement in patients with mucopolysaccharidosis type II: a nationwide survey in Japan. Mol Genet Metab (2012) 1.30

CD147 and matrix metalloproteinase-2 protein expression as significant prognostic factors in esophageal squamous cell carcinoma. Cancer (2004) 1.27

Xenobiotic kidney organogenesis from human mesenchymal stem cells using a growing rodent embryo. J Am Soc Nephrol (2006) 1.19

The advantages and disadvantages of a Roux-en-Y reconstruction after a distal gastrectomy for gastric cancer. Surg Today (2009) 1.18

A simple and novel technique for the placement of antiadhesive membrane in laparoscopic surgery. Surg Laparosc Endosc Percutan Tech (2008) 1.18

Wandering spleen with chronic torsion. Am J Surg (2008) 1.14

Comparison of anchoring capacity of mesh fixation devices in ventral hernia surgery. Surg Laparosc Endosc Percutan Tech (2009) 1.14

Serum vitamin D levels and survival of patients with colorectal cancer: post-hoc analysis of a prospective cohort study. BMC Cancer (2010) 1.09

Hemangiopericytoma of the greater omentum. J Gastrointest Surg (2007) 1.08

Doxycycline induces apoptosis in PANC-1 pancreatic cancer cells. Anticancer Res (2009) 1.07

Implantation of rectal cancer in an anal fistula: report of a case. Surg Today (2006) 1.07

Reconstituted high-density lipoprotein stimulates differentiation of endothelial progenitor cells and enhances ischemia-induced angiogenesis. Arterioscler Thromb Vasc Biol (2007) 1.06

Significance of screening for Fabry disease among male dialysis patients. Clin Exp Nephrol (2005) 1.05

Brain transplantation of genetically engineered human neural stem cells globally corrects brain lesions in the mucopolysaccharidosis type VII mouse. J Neurosci Res (2003) 1.05

Clinical usefulness of diffusion-weighted imaging using low and high b-values to detect rectal cancer. Magn Reson Med Sci (2006) 1.03

Genetic association of glutathione peroxidase-1 with coronary artery calcification in type 2 diabetes: a case control study with multi-slice computed tomography. Cardiovasc Diabetol (2007) 1.03

Preoperative serum carcinoembryonic antigen and carbohydrate antigen 19-9 levels for the evaluation of curability and resectability in patients with pancreatic adenocarcinoma. J Hepatobiliary Pancreat Surg (2007) 1.03

Synergistic induction of antigen-specific CTL by fusions of TLR-stimulated dendritic cells and heat-stressed tumor cells. J Immunol (2007) 1.02

A 16-year experience in performing hepatic resection in 303 patients with hepatocellular carcinoma: 1985-2000. Surgery (2002) 1.01

Streptococcal preparation OK-432 promotes fusion efficiency and enhances induction of antigen-specific CTL by fusions of dendritic cells and colorectal cancer cells. J Immunol (2007) 1.00

Relationship between portal venous flow and liver regeneration in patients after living donor right-lobe liver transplantation. Liver Transpl (2003) 0.99

Cytochrome P450 oxidoreductase deficiency in three patients initially regarded as having 21-hydroxylase deficiency and/or aromatase deficiency: diagnostic value of urine steroid hormone analysis. Pediatr Res (2006) 0.99

Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma. Int J Cancer (2013) 0.99

Intrahepatic cholangiocarcinoma mimicking hepatic inflammatory pseudotumor. J Gastrointest Surg (2007) 0.97

Nuclear factor kappa B activation is a potential target for preventing pancreatic carcinoma by aspirin. Cancer (2005) 0.97

Reasons and risk factors for intraoperative conversion from laparoscopic to open cholecystectomy. Surg Today (2012) 0.97

Successful treatment of advanced gallbladder cancer with an anticancer drug S-1: assessment based on intratumoral gene. Int J Clin Oncol (2008) 0.96

Dendritic cells fused with allogeneic colorectal cancer cell line present multiple colorectal cancer-specific antigens and induce antitumor immunity against autologous tumor cells. Clin Cancer Res (2005) 0.96

Where is the best surgical incision for laparoscopic anterior resection? Hepatogastroenterology (2010) 0.96

Profiling gene expression ratios of paired cancerous and normal tissue predicts relapse of esophageal squamous cell carcinoma. Cancer Res (2003) 0.95

Single-incision laparoscopic splenectomy using the "tug-exposure technique" in adults: results of ten initial cases. Surg Endosc (2011) 0.95

The herbal medicine Dai-Kenchu-To directly stimulates colonic motility. Surg Today (2009) 0.95

Transplantation of adipose stromal cells, but not mature adipocytes, augments ischemia-induced angiogenesis. Life Sci (2006) 0.94

Elevated urine pregnanetriolone definitively establishes the diagnosis of classical 21-hydroxylase deficiency in term and preterm neonates. J Clin Endocrinol Metab (2004) 0.93

Induced pluripotent stem cells derived from mouse models of lysosomal storage disorders. Proc Natl Acad Sci U S A (2010) 0.93

Expression of vascular endothelial growth factor (VEGF)-C and -D in gastric carcinoma. Int J Clin Oncol (2006) 0.93

Prognostic significance of vascular endothelial growth factor D in gastric carcinoma. World J Surg (2005) 0.92

Single-incision laparoscopic distal pancreatectomy with or without splenic preservation: how we do it. Asian J Endosc Surg (2012) 0.91

Results after laparoscopic Heller-Dor operation for esophageal achalasia in 100 consecutive patients. Dis Esophagus (2008) 0.91

Use of a modified alpha-N-acetylgalactosaminidase in the development of enzyme replacement therapy for Fabry disease. Am J Hum Genet (2009) 0.91

Glucose triggers ATP secretion from bacteria in a growth-phase-dependent manner. Appl Environ Microbiol (2013) 0.91

Combination chemotherapy of nafamostat mesilate with gemcitabine for pancreatic cancer targeting NF-kappaB activation. Anticancer Res (2009) 0.91

Function of polo-like kinase 3 in NF-kappaB-mediated proapoptotic response. J Biol Chem (2005) 0.91

Acute tumor lysis syndrome after transarterial chemoembolization for hepatocellular carcinoma. Cancer Sci (2008) 0.91

Living donor liver transplantation with extensive caval thrombectomy for acute-on-chronic Budd-Chiari syndrome. Surg Today (2011) 0.90

Usefulness of automatic triangular anastomosis for esophageal cancer surgery using a linear stapler (TA-30). Ann Thorac Cardiovasc Surg (2005) 0.90

The Glasgow prognostic score is valuable for colorectal cancer with both synchronous and metachronous unresectable liver metastases. Oncol Lett (2012) 0.90

Perioperative change in peripheral blood monocyte count may predict prognosis in patients with colorectal liver metastasis after hepatic resection. J Surg Oncol (2012) 0.90

The efficiency of micrometastasis by sentinel node navigation surgery using indocyanine green and infrared ray laparoscopy system for gastric cancer. Gastric Cancer (2011) 0.90

Minimizing intraoperative bleeding using a vessel-sealing system and splenic hilum hanging maneuver in laparoscopic splenectomy. J Hepatobiliary Pancreat Surg (2009) 0.89

No accumulation of globotriaosylceramide in the heart of a patient with the E66Q mutation in the α-galactosidase A gene. Mol Genet Metab (2012) 0.89

Anastomosis Procedure through an Inguinal Hernia Incision in Simultaneous Laparoscopic Anterior Resection and Inguinal Hernia Repair. J Surg Tech Case Rep (2011) 0.89

Adenoviral gene transfer of GDNF, BDNF and TGF beta 2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motoneurons after facial nerve avulsion. J Neurosci Res (2003) 0.89

Thoracic aortic injury during laparoscopic fundoplication for reflux esophagitis. Int J Surg (2006) 0.88

Phosphatidylinositol 5-phosphate 4-kinase type II beta is required for vitamin D receptor-dependent E-cadherin expression in SW480 cells. Biochem Biophys Res Commun (2011) 0.88

Human Shugoshin mediates kinetochore-driven formation of kinetochore microtubules. Cell Cycle (2006) 0.88

Non-invasive screening method for Fabry disease by measuring globotriaosylceramide in whole urine samples using tandem mass spectrometry. Mol Genet Metab (2005) 0.88