Published in Nutr Metab Cardiovasc Dis on August 17, 2012
You're only as old as your arteries: translational strategies for preserving vascular endothelial function with aging. Physiology (Bethesda) (2014) 1.04
Aerobic exercise and other healthy lifestyle factors that influence vascular aging. Adv Physiol Educ (2014) 0.92
Sarcopenic obesity and endocrinal adaptation with age. Int J Endocrinol (2013) 0.91
Treatment of Obesity: Weight Loss and Bariatric Surgery. Circ Res (2016) 0.83
Sarcopenia Is Associated With Lower Skeletal Muscle Capillarization and Exercise Capacity in Older Adults. J Gerontol A Biol Sci Med Sci (2016) 0.77
Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial. Br J Nutr (2015) 0.76
Relationship Between Sarcopenia and Albuminuria: The 2011 Korea National Health and Nutrition Examination Survey. Medicine (Baltimore) (2016) 0.75
Pre-sarcopenia is associated with renal hyperfiltration independent of obesity or insulin resistance: Nationwide Surveys (KNHANES 2008-2011). Medicine (Baltimore) (2017) 0.75
Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing (2010) 17.45
Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol (1998) 10.23
Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc (2002) 8.28
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest (2003) 6.30
Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle. FASEB J (2004) 4.41
Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women. J Gerontol A Biol Sci Med Sci (2002) 3.98
Basal muscle amino acid kinetics and protein synthesis in healthy young and older men. JAMA (2001) 3.85
Age-related reduction of NO availability and oxidative stress in humans. Hypertension (2001) 3.37
Skeletal muscle cutpoints associated with elevated physical disability risk in older men and women. Am J Epidemiol (2004) 3.33
Frailty in older men: prevalence, progression, and relationship with mortality. J Am Geriatr Soc (2007) 3.15
Tetrahydrobiopterin augments endothelium-dependent dilatation in sedentary but not in habitually exercising older adults. J Physiol (2005) 2.86
TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle. FASEB J (2005) 2.81
A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly. Am J Physiol Endocrinol Metab (2006) 2.80
A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis. Circulation (2002) 2.76
The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly. J Clin Endocrinol Metab (2000) 2.74
Age-related inflammatory cytokines and disease. Immunol Allergy Clin North Am (2003) 2.73
Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives. J Nutr Health Aging (2008) 2.54
Aging and vascular endothelial function in humans. Clin Sci (Lond) (2011) 2.53
Endothelial aging. Cardiovasc Res (2005) 2.46
Human muscle protein synthesis is modulated by extracellular, not intramuscular amino acid availability: a dose-response study. J Physiol (2003) 2.39
Nutrient signalling in the regulation of human muscle protein synthesis. J Physiol (2007) 2.22
Insulin resistance of muscle protein metabolism in aging. FASEB J (2006) 2.17
Dietary factors and low-grade inflammation in relation to overweight and obesity. Br J Nutr (2011) 2.16
Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids. Am J Clin Nutr (2005) 2.15
Aging progressively impairs endothelium-dependent vasodilation in forearm resistance vessels of humans. Hypertension (1996) 2.03
Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging. Am J Pathol (2007) 2.02
Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans. Circulation (2009) 1.99
Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humans. FASEB J (2004) 1.95
Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein. Circulation (2002) 1.94
Aerobic exercise, but not flexibility/resistance exercise, reduces serum IL-18, CRP, and IL-6 independent of beta-blockers, BMI, and psychosocial factors in older adults. Brain Behav Immun (2006) 1.86
Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase. Am J Physiol Heart Circ Physiol (2009) 1.81
A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. J Am Diet Assoc (2009) 1.70
Dietary omega-3 fatty acid supplementation increases the rate of muscle protein synthesis in older adults: a randomized controlled trial. Am J Clin Nutr (2010) 1.63
Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein. Exp Gerontol (2005) 1.53
Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling. Diabetes (2007) 1.50
Heterogeneous vasodilator responses of human limbs: influence of age and habitual endurance training. Am J Physiol Heart Circ Physiol (2005) 1.28
Falls, sarcopenia, and growth in early life: findings from the Hertfordshire cohort study. Am J Epidemiol (2006) 1.28
Blunting of insulin inhibition of proteolysis in legs of older subjects may contribute to age-related sarcopenia. Am J Clin Nutr (2009) 1.28
Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production. Atherosclerosis (2005) 1.28
Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence. Exp Gerontol (2003) 1.25
Sex-specific effects of habitual aerobic exercise on brachial artery flow-mediated dilation in middle-aged and older adults. Clin Sci (Lond) (2011) 1.24
Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signaling. J Clin Endocrinol Metab (2010) 1.24
Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium. Curr Diab Rep (2003) 1.24
Effects of a low-salt diet on flow-mediated dilatation in humans. Am J Clin Nutr (2008) 1.17
Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of muscle protein metabolism. Diabetologia (2009) 1.15
Age-related changes in endothelial function and blood flow regulation. Pharmacol Ther (2011) 1.14
Pharmacological vasodilation improves insulin-stimulated muscle protein anabolism but not glucose utilization in older adults. Diabetes (2010) 1.13
Endothelin-1 modulates insulin signaling through phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells. Diabetes (1999) 1.10
ROS and myokines promote muscle adaptation to exercise. Trends Endocrinol Metab (2009) 1.07
Dietary intake of fruits and vegetables improves microvascular function in hypertensive subjects in a dose-dependent manner. Circulation (2009) 1.07
Increased availability of leucine with leucine-rich whey proteins improves postprandial muscle protein synthesis in aging rats. Nutrition (2007) 1.04
Impact of n-3 fatty acids on endothelial function: results from human interventions studies. Curr Opin Clin Nutr Metab Care (2011) 0.97
Effect of inflammation on the aging microcirculation: impact on skeletal muscle blood flow control. Microcirculation (2006) 0.97
Dietary protein digestion and absorption rates and the subsequent postprandial muscle protein synthetic response do not differ between young and elderly men. J Nutr (2009) 0.96
Decreased natural killer cell activity is associated with atherosclerosis in elderly humans. Exp Gerontol (2001) 0.96
Tempol improves vascular function in the mesenteric vascular bed of senescent rats. Can J Physiol Pharmacol (2004) 0.87
Effect of weight loss on the rate of muscle protein synthesis during fasted and fed conditions in obese older adults. Obesity (Silver Spring) (2011) 0.87
Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women. Med Sci Monit (2011) 0.86
Cardiovascular and endothelial effects of fish oil supplementation in healthy volunteers. J Cardiovasc Pharmacol Ther (2007) 0.85
Endothelial dysfunction associated with obesity and the effect of weight loss interventions. Proc Nutr Soc (2011) 0.84
Regulation of glucose uptake by endothelin-1 in human skeletal muscle in vivo and in vitro. J Clin Endocrinol Metab (2010) 0.83