Christopher C Glembotski

Author PubWeight™ 42.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6. Circ Res 2006 2.95
2 Pim-1 regulates cardiomyocyte survival downstream of Akt. Nat Med 2007 2.39
3 Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes. Circ Res 2006 2.09
4 Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis. Circ Res 2003 1.99
5 LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. Am J Physiol Heart Circ Physiol 2008 1.97
6 Atrial natriuretic peptide promotes cardiomyocyte survival by cGMP-dependent nuclear accumulation of zyxin and Akt. J Clin Invest 2005 1.70
7 Ischemia activates the ATF6 branch of the endoplasmic reticulum stress response. J Biol Chem 2009 1.48
8 Activation of p38 has opposing effects on the proliferation and migration of endothelial cells. J Biol Chem 2005 1.32
9 Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene. J Biol Chem 2008 1.28
10 Mesencephalic astrocyte-derived neurotrophic factor is an ischemia-inducible secreted endoplasmic reticulum stress response protein in the heart. Circ Res 2008 1.28
11 Roles for alphaB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model. Am J Physiol Heart Circ Physiol 2003 1.24
12 The cardiokine story unfolds: ischemic stress-induced protein secretion in the heart. Trends Mol Med 2011 1.24
13 Pim-1 kinase protects mitochondrial integrity in cardiomyocytes. Circ Res 2010 1.21
14 Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo. J Biol Chem 2004 1.20
15 Coordination of ATF6-mediated transcription and ATF6 degradation by a domain that is shared with the viral transcription factor, VP16. J Biol Chem 2002 1.16
16 Effects of the isoform-specific characteristics of ATF6 alpha and ATF6 beta on endoplasmic reticulum stress response gene expression and cell viability. J Biol Chem 2007 1.14
17 Opposing roles for ATF6alpha and ATF6beta in endoplasmic reticulum stress response gene induction. J Biol Chem 2004 1.14
18 Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage. Circulation 2013 1.06
19 Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1. Proc Natl Acad Sci U S A 2013 1.02
20 Roles for endoplasmic reticulum-associated degradation and the novel endoplasmic reticulum stress response gene Derlin-3 in the ischemic heart. Circ Res 2009 0.97
21 Alterations in oxidative phosphorylation complex proteins in the hearts of transgenic mice that overexpress the p38 MAP kinase activator, MAP kinase kinase 6. Am J Physiol Heart Circ Physiol 2006 0.95
22 New concepts of endoplasmic reticulum function in the heart: programmed to conserve. J Mol Cell Cardiol 2012 0.95
23 Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response. J Cell Sci 2012 0.93
24 Protein disulfide isomerase-associated 6 is an ATF6-inducible ER stress response protein that protects cardiac myocytes from ischemia/reperfusion-mediated cell death. J Mol Cell Cardiol 2012 0.93
25 Regulation of microRNA expression in the heart by the ATF6 branch of the ER stress response. J Mol Cell Cardiol 2012 0.92
26 PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity. EMBO Mol Med 2014 0.91
27 MAP kinase kinase 6-p38 MAP kinase signaling cascade regulates cyclooxygenase-2 expression in cardiac myocytes in vitro and in vivo. Circ Res 2003 0.88
28 Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1. Circ Res 2013 0.88
29 Factor associated with neutral sphingomyelinase activation and its role in cardiac cell death. Circ Res 2003 0.85
30 The MKK6-p38 MAPK pathway prolongs the cardiac contractile calcium transient, downregulates SERCA2, and activates NF-AT. Cardiovasc Res 2003 0.84
31 Clarifying the cardiac proteasome paradox: protein quality control. Circ Res 2012 0.81
32 ATF6 [corrected] and thrombospondin 4: the dynamic duo of the adaptive endoplasmic reticulum stress response. Circ Res 2013 0.80
33 The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels. Arterioscler Thromb Vasc Biol 2009 0.79
34 Guanine nucleotide exchange factor-like factor (Rlf) induces gene expression and potentiates alpha 1-adrenergic receptor-induced transcriptional responses in neonatal rat ventricular myocytes. J Biol Chem 2002 0.78
35 Expression and functional characterization of SCaMPER: a sphingolipid-modulated calcium channel of cardiomyocytes. Am J Physiol Cell Physiol 2002 0.77