Published in Circ Res on August 17, 2012
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Genetically induced moderate inhibition of the proteasome in cardiomyocytes exacerbates myocardial ischemia-reperfusion injury in mice. Circ Res (2012) 1.15
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Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6. Circ Res (2006) 2.95
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Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes. Circ Res (2006) 2.09
Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis. Circ Res (2003) 1.99
LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. Am J Physiol Heart Circ Physiol (2008) 1.97
Atrial natriuretic peptide promotes cardiomyocyte survival by cGMP-dependent nuclear accumulation of zyxin and Akt. J Clin Invest (2005) 1.70
Ischemia activates the ATF6 branch of the endoplasmic reticulum stress response. J Biol Chem (2009) 1.48
Activation of p38 has opposing effects on the proliferation and migration of endothelial cells. J Biol Chem (2005) 1.32
Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene. J Biol Chem (2008) 1.28
Mesencephalic astrocyte-derived neurotrophic factor is an ischemia-inducible secreted endoplasmic reticulum stress response protein in the heart. Circ Res (2008) 1.28
The cardiokine story unfolds: ischemic stress-induced protein secretion in the heart. Trends Mol Med (2011) 1.24
Roles for alphaB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model. Am J Physiol Heart Circ Physiol (2003) 1.24
Pim-1 kinase protects mitochondrial integrity in cardiomyocytes. Circ Res (2010) 1.21
Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo. J Biol Chem (2004) 1.20
Coordination of ATF6-mediated transcription and ATF6 degradation by a domain that is shared with the viral transcription factor, VP16. J Biol Chem (2002) 1.16
Effects of the isoform-specific characteristics of ATF6 alpha and ATF6 beta on endoplasmic reticulum stress response gene expression and cell viability. J Biol Chem (2007) 1.14
Opposing roles for ATF6alpha and ATF6beta in endoplasmic reticulum stress response gene induction. J Biol Chem (2004) 1.14
Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage. Circulation (2013) 1.06
Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1. Proc Natl Acad Sci U S A (2013) 1.02
Roles for endoplasmic reticulum-associated degradation and the novel endoplasmic reticulum stress response gene Derlin-3 in the ischemic heart. Circ Res (2009) 0.97
Alterations in oxidative phosphorylation complex proteins in the hearts of transgenic mice that overexpress the p38 MAP kinase activator, MAP kinase kinase 6. Am J Physiol Heart Circ Physiol (2006) 0.95
New concepts of endoplasmic reticulum function in the heart: programmed to conserve. J Mol Cell Cardiol (2012) 0.95
Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response. J Cell Sci (2012) 0.93
Protein disulfide isomerase-associated 6 is an ATF6-inducible ER stress response protein that protects cardiac myocytes from ischemia/reperfusion-mediated cell death. J Mol Cell Cardiol (2012) 0.93
Regulation of microRNA expression in the heart by the ATF6 branch of the ER stress response. J Mol Cell Cardiol (2012) 0.92
PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity. EMBO Mol Med (2014) 0.91
Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1. Circ Res (2013) 0.88
MAP kinase kinase 6-p38 MAP kinase signaling cascade regulates cyclooxygenase-2 expression in cardiac myocytes in vitro and in vivo. Circ Res (2003) 0.88
Factor associated with neutral sphingomyelinase activation and its role in cardiac cell death. Circ Res (2003) 0.85
The MKK6-p38 MAPK pathway prolongs the cardiac contractile calcium transient, downregulates SERCA2, and activates NF-AT. Cardiovasc Res (2003) 0.84
ATF6 [corrected] and thrombospondin 4: the dynamic duo of the adaptive endoplasmic reticulum stress response. Circ Res (2013) 0.80
The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels. Arterioscler Thromb Vasc Biol (2009) 0.79
Guanine nucleotide exchange factor-like factor (Rlf) induces gene expression and potentiates alpha 1-adrenergic receptor-induced transcriptional responses in neonatal rat ventricular myocytes. J Biol Chem (2002) 0.78
Expression and functional characterization of SCaMPER: a sphingolipid-modulated calcium channel of cardiomyocytes. Am J Physiol Cell Physiol (2002) 0.77