Published in Angew Chem Int Ed Engl on August 21, 2012
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Biomolecular robotics for chemomechanically driven guest delivery fuelled by intracellular ATP. Nat Chem (2013) 0.94
ATP-responsive DNA-graphene hybrid nanoaggregates for anticancer drug delivery. Biomaterials (2015) 0.84
Green Tea Catechin-Based Complex Micelles Combined with Doxorubicin to Overcome Cardiotoxicity and Multidrug Resistance. Theranostics (2016) 0.82
Self-assembly of random copolymers. Chem Commun (Camb) (2014) 0.78
One-pot synthesis of pH-responsive hybrid nanogel particles for the intracellular delivery of small interfering RNA. Biomaterials (2016) 0.76
Simultaneous expression and transportation of insulin by supramolecular polysaccharide nanocluster. Sci Rep (2016) 0.75
Future nanomedicine for the diagnosis and treatment of osteoarthritis. Nanomedicine (Lond) (2014) 0.75
Dynamically Tunable Cell Culture Platforms for Tissue Engineering and Mechanobiology. Prog Polym Sci (2016) 0.75
ATP-Responsive and Near-Infrared-Emissive Nanocarriers for Anticancer Drug Delivery and Real-Time Imaging. Theranostics (2016) 0.75
Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery. Sensors (Basel) (2016) 0.75
Current Multistage Drug Delivery Systems Based on the Tumor Microenvironment. Theranostics (2017) 0.75
Systemic siRNA Delivery with a Dual pH-Responsive and Tumor-targeted Nanovector for Inhibiting Tumor Growth and Spontaneous Metastasis in Orthotopic Murine Model of Breast Carcinoma. Theranostics (2017) 0.75
PEGylated nanoparticles for biological and pharmaceutical applications. Adv Drug Deliv Rev (2003) 3.19
Genome-wide transcriptional orchestration of circadian rhythms in Drosophila. J Biol Chem (2002) 2.64
Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery. Pharmacol Ther (2006) 2.48
Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice. Cancer Res (2003) 2.47
Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change. Angew Chem Int Ed Engl (2003) 2.37
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling. Proc Natl Acad Sci U S A (2007) 2.30
Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery. Mol Biosyst (2005) 1.92
Preclinical and clinical studies of anticancer agent-incorporating polymer micelles. Cancer Sci (2009) 1.88
Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy. Bioconjug Chem (2005) 1.82
Silk microspheres for encapsulation and controlled release. J Control Release (2006) 1.81
Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells. J Am Chem Soc (2005) 1.66
siRNA-based therapy ameliorates glomerulonephritis. J Am Soc Nephrol (2010) 1.58
Block copolymer micelles for delivery of gene and related compounds. Adv Drug Deliv Rev (2002) 1.56
In situ quantitative monitoring of polyplexes and polyplex micelles in the blood circulation using intravital real-time confocal laser scanning microscopy. J Control Release (2011) 1.55
3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells. Biomaterials (2009) 1.50
Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEG. ACS Nano (2012) 1.49
Enhanced photodynamic cancer treatment by supramolecular nanocarriers charged with dendrimer phthalocyanine. J Control Release (2008) 1.49
Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression. J Am Chem Soc (2004) 1.46
Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers. Adv Drug Deliv Rev (2009) 1.45
Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation. Proc Natl Acad Sci U S A (2002) 1.42
Biodegradable nanogels prepared by atom transfer radical polymerization as potential drug delivery carriers: synthesis, biodegradation, in vitro release, and bioconjugation. J Am Chem Soc (2007) 1.38
PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors. J Am Chem Soc (2008) 1.35
Biomaterial coatings by stepwise deposition of silk fibroin. Langmuir (2005) 1.34
Polyplexes from poly(aspartamide) bearing 1,2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity. J Am Chem Soc (2008) 1.30
In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments. Bioconjug Chem (2007) 1.29
A PEG-based biocompatible block catiomer with high buffering capacity for the construction of polyplex micelles showing efficient gene transfer toward primary cells. ChemMedChem (2006) 1.28
Supramolecular nanodevices: from design validation to theranostic nanomedicine. Acc Chem Res (2011) 1.28
The period gene and allochronic reproductive isolation in Bactrocera cucurbitae. Proc Biol Sci (2002) 1.26
SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells. Immunity (2003) 1.26
Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting. Sci Transl Med (2011) 1.26
Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery. Biomacromolecules (2009) 1.25
pH-responsive three-layered PEGylated polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable and endosome-disruptive nonviral gene vector. Bioconjug Chem (2006) 1.24
Silk Fibroin Microfluidic Devices. Adv Mater (2007) 1.21
Angiosarcoma treated with radiotherapy: impact of tumor type and size on outcome. Int J Radiat Oncol Biol Phys (2002) 1.19
Parotid tumors: MR imaging with pathological correlation. Eur Radiol (2003) 1.19
Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer. Nat Mater (2005) 1.17
Block copolymer-coated calcium phosphate nanoparticles sensing intracellular environment for oligodeoxynucleotide and siRNA delivery. J Control Release (2004) 1.15
Temperature cycles drive Drosophila circadian oscillation in constant light that otherwise induces behavioural arrhythmicity. Eur J Neurosci (2005) 1.15
Charge-conversion ternary polyplex with endosome disruption moiety: a technique for efficient and safe gene delivery. Angew Chem Int Ed Engl (2008) 1.14
Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles. Mol Ther (2007) 1.13
Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization. Nat Commun (2013) 1.12
Evaluation by fluorescence resonance energy transfer of the stability of nonviral gene delivery vectors under physiological conditions. Biomacromolecules (2002) 1.12
Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm. Angew Chem Int Ed Engl (2009) 1.12
Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimizing cumulative toxicity. Biomaterials (2010) 1.12
Two-dimensional multiarray formation of hepatocyte spheroids on a microfabricated PEG-brush surface. Chembiochem (2004) 1.12
Regulation of alkaline phosphatase promoter activity by forkhead transcription factor FKHR. Int J Mol Med (2002) 1.12
Enhancement of angiogenesis through stabilization of hypoxia-inducible factor-1 by silencing prolyl hydroxylase domain-2 gene. Mol Ther (2008) 1.11
Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor-beta receptor inhibitor on extravasation of nanoparticles from neovasculature. Cancer Sci (2008) 1.10
Rational design of smart supramolecular assemblies for gene delivery: chemical challenges in the creation of artificial viruses. Chem Soc Rev (2011) 1.10
Cyclic RGD peptide-conjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins. Bioconjug Chem (2007) 1.09
A comparative view of insect circadian clock systems. Cell Mol Life Sci (2009) 1.09
Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies. J Control Release (2007) 1.08
Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles. J Control Release (2005) 1.08
A protein nanocarrier from charge-conversion polymer in response to endosomal pH. J Am Chem Soc (2007) 1.06
An endoderm-specific GATA factor gene, dGATAe, is required for the terminal differentiation of the Drosophila endoderm. Dev Biol (2005) 1.06
Expression of receptor activator of NF-kappa B ligand and osteoprotegerin in culture of human periodontal ligament cells. J Periodontal Res (2002) 1.06
Glucose-responsive polymer gel bearing phenylborate derivative as a glucose-sensing moiety operating at the physiological pH. Biomacromolecules (2004) 1.05
A core-shell-type fluorescent nanosphere possessing reactive poly(ethylene glycol) tethered chains on the surface for zeptomole detection of protein in time-resolved fluorometric immunoassay. Anal Chem (2003) 1.04
Drosophila cryb mutation reveals two circadian clocks that drive locomotor rhythm and have different responsiveness to light. J Insect Physiol (2004) 1.04
Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit. J Biol Chem (2010) 1.03
Organic-inorganic hybrid-nanocarrier of siRNA constructing through the self-assembly of calcium phosphate and PEG-based block aniomer. J Control Release (2006) 1.03
Polyion complex micelles from plasmid DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer as serum-tolerable polyplex system: physicochemical properties of micelles relevant to gene transfection efficiency. Biomaterials (2003) 1.03
Freeze-dried formulations for in vivo gene delivery of PEGylated polyplex micelles with disulfide crosslinked cores to the liver. J Control Release (2005) 1.03
Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity. J Control Release (2007) 1.02
Cyclic RGD-linked polymeric micelles for targeted delivery of platinum anticancer drugs to glioblastoma through the blood-brain tumor barrier. ACS Nano (2013) 1.02
Iron hydroxide nanoparticles coated with poly(ethylene glycol)-poly(aspartic acid) block copolymer as novel magnetic resonance contrast agents for in vivo cancer imaging. Colloids Surf B Biointerfaces (2007) 1.01
Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection. ACS Nano (2012) 1.01
Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking. Mol Pharm (2009) 1.01
What amount of metallic impurities in carbon nanotubes is small enough not to dominate their redox properties? Nanoscale (2009) 1.00
In situ single cell observation by fluorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine. J Gene Med (2004) 0.99
Preparation of a novel PEG-clay hybrid as a DDS material: dispersion stability and sustained release profiles. J Control Release (2005) 0.99
Recent development of nonviral gene delivery systems with virus-like structures and mechanisms. Eur J Pharm Biopharm (2008) 0.98
Direct and instantaneous observation of intravenously injected substances using intravital confocal micro-videography. Biomed Opt Express (2010) 0.98
Noninvasive sialic acid detection at cell membrane by using phenylboronic acid modified self-assembled monolayer gold electrode. J Am Chem Soc (2009) 0.97
Preparation of bionanoreactor based on core-shell structured polyion complex micelles entrapping trypsin in the core cross-linked with glutaraldehyde. Bioconjug Chem (2004) 0.97
Anomalous binding profile of phenylboronic acid with N-acetylneuraminic acid (Neu5Ac) in aqueous solution with varying pH. J Am Chem Soc (2003) 0.97
PEGylated polyplex micelles from triblock catiomers with spatially ordered layering of condensed pDNA and buffering units for enhanced intracellular gene delivery. J Am Chem Soc (2005) 0.96
Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side chain with distinctive pKa directed to enhance intracellular gene silencing. J Am Chem Soc (2004) 0.96