PubRank

Martin Klingenspor

Author PubWeight™ 94.35‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 2006 7.35
2 A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell 2009 3.63
3 Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. PLoS Genet 2010 3.21
4 Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes. Science 2010 2.93
5 Uncoupling protein 1 expression and high-fat diets. Am J Physiol Regul Integr Comp Physiol 2010 2.42
6 Rapamycin extends murine lifespan but has limited effects on aging. J Clin Invest 2013 2.23
7 Introducing the German Mouse Clinic: open access platform for standardized phenotyping. Nat Methods 2005 1.93
8 Proteome differences between brown and white fat mitochondria reveal specialized metabolic functions. Cell Metab 2009 1.50
9 Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis. PLoS Biol 2013 1.48
10 Mouse phenotyping. Methods 2010 1.43
11 Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43. J Biol Chem 2014 1.37
12 Systemic first-line phenotyping. Methods Mol Biol 2009 1.26
13 Uncoupling protein 1 in fish uncovers an ancient evolutionary history of mammalian nonshivering thermogenesis. Physiol Genomics 2005 1.20
14 Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice. Am J Physiol Regul Integr Comp Physiol 2010 1.18
15 Rapid single step subcloning procedure by combined action of type II and type IIs endonucleases with ligase. J Biol Eng 2007 1.12
16 Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells. Nat Commun 2011 1.12
17 Innovations in phenotyping of mouse models in the German Mouse Clinic. Mamm Genome 2012 1.09
18 Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice. J Biol Chem 2011 1.05
19 A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model. Arthritis Rheum 2011 1.04
20 Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism. Am J Physiol Renal Physiol 2009 1.02
21 Metabolic phenotyping of the Crohn's disease-like IBD etiopathology in the TNF(ΔARE/WT) mouse model. J Proteome Res 2011 1.01
22 Gene or size: metabolic rate and body temperature in obese growth hormone-deficient dwarf mice. Obes Res 2004 1.00
23 High fat diet accelerates pathogenesis of murine Crohn's disease-like ileitis independently of obesity. PLoS One 2013 1.00
24 Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype. PLoS One 2012 0.99
25 Structural features and bioavailability of four flavonoids and their implications for lifespan-extending and antioxidant actions in C. elegans. Mech Ageing Dev 2011 0.99
26 Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice. PLoS One 2010 0.97
27 CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice. EMBO J 2010 0.96
28 Functional characterisation of UCP1 in the common carp: uncoupling activity in liver mitochondria and cold-induced expression in the brain. J Comp Physiol B 2007 0.95
29 A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity. Endocrinology 2004 0.95
30 Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis. BMC Evol Biol 2009 0.95
31 Glucocorticoid hormone stimulates mitochondrial biogenesis specifically in skeletal muscle. Endocrinology 2002 0.94
32 Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon. Genome Res 2014 0.94
33 Evidence for Nr4a1 as a cold-induced effector of brown fat thermogenesis. Physiol Genomics 2005 0.94
34 Expanding the body mass range: associations between BMR and tissue morphology in wild type and mutant dwarf mice (David mice). J Comp Physiol B 2006 0.93
35 Photoperiodic regulation of leptin sensitivity in the Siberian hamster, Phodopus sungorus, is reflected in arcuate nucleus SOCS-3 (suppressor of cytokine signaling) gene expression. Endocrinology 2003 0.92
36 A role for brain-derived neurotrophic factor in B cell development. J Neuroimmunol 2005 0.92
37 Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system. PLoS One 2012 0.92
38 Power matters in closing the phenotyping gap. Naturwissenschaften 2007 0.89
39 A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice. PLoS One 2013 0.89
40 Nuclear receptor cofactor receptor interacting protein 140 controls hepatic triglyceride metabolism during wasting in mice. Hepatology 2008 0.89
41 The molecular and biochemical basis of nonshivering thermogenesis in an African endemic mammal, Elephantulus myurus. Am J Physiol Regul Integr Comp Physiol 2007 0.89
42 Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 ( 416insG ) mice. Mamm Genome 2009 0.89
43 Behavioural mechanisms affecting energy regulation in mice prone or resistant to diet- induced obesity. Physiol Behav 2009 0.88
44 Rescue of melanocortin 4 receptor (MC4R) nonsense mutations by aminoglycoside-mediated read-through. Obesity (Silver Spring) 2011 0.88
45 Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants. BMC Med Genomics 2012 0.87
46 Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology. FASEB J 2012 0.87
47 Normal distribution of body weight gain in male Sprague-Dawley rats fed a high-energy diet. Obes Res 2003 0.87
48 High energy digestion efficiency and altered lipid metabolism contribute to obesity in BFMI mice. Obesity (Silver Spring) 2009 0.87
49 SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities. DNA Repair (Amst) 2013 0.86
50 Brown adipose tissue specific lack of uncoupling protein 3 is associated with impaired cold tolerance and reduced transcript levels of metabolic genes. J Comp Physiol B 2007 0.86
51 Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. PLoS One 2009 0.85
52 Test systems to study the structure and function of uncoupling protein 1: a critical overview. Front Endocrinol (Lausanne) 2011 0.84
53 Functional characterization of UCP1 in mammalian HEK293 cells excludes mitochondrial uncoupling artefacts and reveals no contribution to basal proton leak. Biochim Biophys Acta 2012 0.83
54 Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans. PLoS Genet 2012 0.83
55 Photoperiodic regulation of leptin resistance in the seasonally breeding Siberian hamster (Phodopus sungorus). Endocrinology 2002 0.83
56 Photoperiodic regulation of insulin receptor mRNA and intracellular insulin signaling in the arcuate nucleus of the Siberian hamster, Phodopus sungorus. Am J Physiol Regul Integr Comp Physiol 2006 0.83
57 The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis. FASEB J 2012 0.83
58 High-fat diet induced isoform changes of the Parkinson's disease protein DJ-1. J Proteome Res 2014 0.83
59 Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets. Part Fibre Toxicol 2011 0.82
60 Diet-induced obesity causes metabolic impairment independent of alterations in gut barrier integrity. Mol Nutr Food Res 2015 0.82
61 Uncoupling protein 2 and 3 in marsupials: identification, phylogeny, and gene expression in response to cold and fasting in Antechinus flavipes. Physiol Genomics 2004 0.82
62 Brown fat develops a brite future. Obes Facts 2012 0.81
63 Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients. Acta Neuropathol 2012 0.81
64 Standardized, systemic phenotypic analysis of Umod(C93F) and Umod(A227T) mutant mice. PLoS One 2013 0.80
65 Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome. Obes Facts 2009 0.80
66 Neuronal distribution of melanin-concentrating hormone, cocaine- and amphetamine-regulated transcript and orexin B in the brain of the Djungarian hamster (Phodopus sungorus). J Chem Neuroanat 2005 0.80
67 An intronic single base exchange leads to a brown adipose tissue-specific loss of Ucp3 expression and an altered body mass trajectory. Physiol Genomics 2009 0.80
68 Chicken ovalbumin upstream promoter transcription factor II regulates uncoupling protein 3 gene transcription in Phodopus sungorus. BMC Mol Biol 2007 0.80
69 A review of standardized metabolic phenotyping of animal models. Mamm Genome 2014 0.80
70 Wheel running affects seasonal acclimatization of physiological and morphological traits in the Djungarian hamster (Phodopus sungorus). Am J Physiol Regul Integr Comp Physiol 2007 0.80
71 Depression of transcription and translation during daily torpor in the Djungarian hamster (Phodopus sungorus). J Comp Physiol B 2004 0.79
72 Seasonal regulation of cocaine- and amphetamine-regulated transcript in the arcuate nucleus of Djungarian hamster (Phodopus sungorus). Gen Comp Endocrinol 2008 0.79
73 PASylation of Murine Leptin Leads to Extended Plasma Half-Life and Enhanced in Vivo Efficacy. Mol Pharm 2015 0.78
74 Glucose tolerance tests for systematic screening of glucose homeostasis in mice. Curr Protoc Mouse Biol 2015 0.78
75 Diet-induced obesity in ad libitum-fed mice: food texture overrides the effect of macronutrient composition. Br J Nutr 2012 0.78
76 Gene set of nuclear-encoded mitochondrial regulators is enriched for common inherited variation in obesity. PLoS One 2013 0.78
77 Limited mitochondrial capacity of visceral versus subcutaneous white adipocytes in male C57BL/6N mice. Endocrinology 2014 0.78
78 Absence of UCP3 in brown adipose tissue does not impair nonshivering thermogenesis. Physiol Biochem Zool 2004 0.78
79 Metabolic phenotyping of mouse mutants in the German Mouse Clinic. Integr Zool 2006 0.77
80 Seasonal leptin resistance is associated with impaired signalling via JAK2-STAT3 but not ERK, possibly mediated by reduced hypothalamic GRB2 protein. J Comp Physiol B 2011 0.77
81 Photoperiodic regulation of satiety mediating neuropeptides in the brainstem of the seasonal Siberian hamster (Phodopus sungorus). J Comp Physiol A Neuroethol Sens Neural Behav Physiol 2009 0.77
82 Mitochondrial proton conductance in skeletal muscle of a cold-exposed marsupial, Antechinus flavipes, is unlikely to be involved in adaptive nonshivering thermogenesis but displays increased sensitivity toward carbon-centered radicals. Physiol Biochem Zool 2009 0.76
83 Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines. Eur J Oral Sci 2012 0.76
84 Boosting mitochondrial biogenesis in white adipocytes: A route towards improved insulin sensitivity? Mol Metab 2013 0.75
85 A functional nexus between photoperiod acclimation, torpor expression and somatic fatty acid composition in a heterothermic mammal. PLoS One 2013 0.75
86 Diet-induced and mono-genetic obesity alter volatile organic compound signature in mice. J Breath Res 2016 0.75
87 Online breath gas analysis in unrestrained mice by hs-PTR-MS. Mamm Genome 2013 0.75
88 2-O-β-D-Glucopyranosyl-carboxyatractyligenin from Coffea L. inhibits adenine nucleotide translocase in isolated mitochondria but is quantitatively degraded during coffee roasting. Phytochemistry 2013 0.75