Published in Neurosci Lett on November 27, 1990
Pedunculopontine and laterodorsal tegmental nuclei contain distinct populations of cholinergic, glutamatergic and GABAergic neurons in the rat. Eur J Neurosci (2009) 2.11
The developmental decrease in REM sleep: the role of transmitters and electrical coupling. Sleep (2008) 1.31
The cholinergic mesopontine tegmentum is a relatively neglected nicotinic master modulator of the dopaminergic system: relevance to drugs of abuse and pathology. Br J Pharmacol (2008) 1.29
Glutamate synaptic inputs to ventral tegmental area neurons in the rat derive primarily from subcortical sources. Neuroscience (2007) 1.25
A glutamatergic reward input from the dorsal raphe to ventral tegmental area dopamine neurons. Nat Commun (2014) 1.21
Activation of afferents to the ventral tegmental area in response to acute amphetamine: a double-labelling study. Eur J Neurosci (2007) 1.08
Identification of cholinergic and non-cholinergic neurons in the pons expressing phosphorylated cyclic adenosine monophosphate response element-binding protein as a function of rapid eye movement sleep. Neuroscience (2009) 1.03
Cholinergic modulation of fast inhibitory and excitatory transmission to pedunculopontine thalamic projecting neurons. J Neurophysiol (2010) 1.00
Protein kinase A in the pedunculopontine tegmental nucleus of rat contributes to regulation of rapid eye movement sleep. J Neurosci (2010) 0.97
Properties of distinct ventral tegmental area synapses activated via pedunculopontine or ventral tegmental area stimulation in vitro. J Physiol (2009) 0.94
Calcium/calmodulin kinase II in the pedunculopontine tegmental nucleus modulates the initiation and maintenance of wakefulness. J Neurosci (2011) 0.94
Intrinsic and integrative properties of substantia nigra pars reticulata neurons. Neuroscience (2011) 0.92
Cholinergic and non-cholinergic mesopontine tegmental neurons projecting to the subthalamic nucleus in the rat. Eur J Neurosci (2010) 0.91
Comparison of systemic and local methamphetamine treatment on acetylcholine and dopamine levels in the ventral tegmental area in the mouse. Neuroscience (2008) 0.91
The mesopontine rostromedial tegmental nucleus: an integrative modulator of the reward system. Basal Ganglia (2011) 0.90
Mesopontine rostromedial tegmental nucleus neurons projecting to the dorsal raphe and pedunculopontine tegmental nucleus: psychostimulant-elicited Fos expression and collateralization. Brain Struct Funct (2011) 0.90
Dopaminergic and cholinergic learning mechanisms in nicotine addiction. Ann N Y Acad Sci (2015) 0.89
Development of REM sleep drive and clinical implications. J Appl Physiol (1985) (2003) 0.83
Reward prediction-related increases and decreases in tonic neuronal activity of the pedunculopontine tegmental nucleus. Front Integr Neurosci (2013) 0.83
Limited access to ethanol increases the number of spontaneously active dopamine neurons in the posterior ventral tegmental area of nondependent P rats. Alcohol (2010) 0.82
A neural correlate of predicted and actual reward-value information in monkey pedunculopontine tegmental and dorsal raphe nucleus during saccade tasks. Neural Plast (2011) 0.82
Projections from auditory cortex to cholinergic cells in the midbrain tegmentum of guinea pigs. Brain Res Bull (2009) 0.82
Gsx1 expression defines neurons required for prepulse inhibition. Mol Psychiatry (2014) 0.81
Brainstem control of locomotion and muscle tone with special reference to the role of the mesopontine tegmentum and medullary reticulospinal systems. J Neural Transm (Vienna) (2015) 0.81
Signals from the brainstem sleep/wake centers regulate behavioral timing via the circadian clock. PLoS One (2013) 0.81
Diversity of Dopaminergic Neural Circuits in Response to Drug Exposure. Neuropsychopharmacology (2016) 0.79
Neurosteroids and cholinergic systems: implications for sleep and cognitive processes and potential role of age-related changes. Psychopharmacology (Berl) (2006) 0.79
Knockouts reveal overlapping functions of M(2) and M(4) muscarinic receptors and evidence for a local glutamatergic circuit within the laterodorsal tegmental nucleus. J Neurophysiol (2012) 0.78
Endogenous cholinergic inputs and local circuit mechanisms govern the phasic mesolimbic dopamine response to nicotine. PLoS Comput Biol (2013) 0.78
Adenosine A1 and A2A receptors are not upstream of caffeine's dopamine D2 receptor-dependent aversive effects and dopamine-independent rewarding effects. Eur J Neurosci (2010) 0.78
Mitochondrial abnormality associates with type-specific neuronal loss and cell morphology changes in the pedunculopontine nucleus in Parkinson disease. Am J Pathol (2013) 0.77
The Pedunculopontine Tegmental Nucleus as a Motor and Cognitive Interface between the Cerebellum and Basal Ganglia. Front Neuroanat (2016) 0.77
Serotonergic modulation of hippocampal theta activity in relation to hippocampal information processing. Exp Brain Res (2013) 0.76
The role of mesopontine NGF in sleep and wakefulness. Brain Res (2011) 0.76
Identification of an excitatory amino acid-mediated component of the ventral tegmental area local field potential response to medial prefrontal cortex stimulation: effect of acute d-amphetamine. J Neural Transm (Vienna) (2006) 0.75
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature (1996) 6.75
Total energy expenditure and physical activity in young Scottish children: mixed longitudinal study. Lancet (2004) 5.06
Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. Proc Natl Acad Sci U S A (1988) 4.19
National Science Foundation-Sponsored Workshop Report: "The 2010 Project" functional genomics and the virtual plant. A blueprint for understanding how plants are built and how to improve them. Plant Physiol (2000) 3.29
Objective measurement of physical activity and sedentary behaviour: review with new data. Arch Dis Child (2008) 3.23
Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway. Proc Natl Acad Sci U S A (1994) 2.22
Orbitofrontal cortex and human drug abuse: functional imaging. Cereb Cortex (2000) 2.04
Plasma ropivacaine concentrations after ultrasound-guided transversus abdominis plane block. Br J Anaesth (2010) 1.90
Differentiation therapy of human cancer: basic science and clinical applications. Pharmacol Ther (2001) 1.71
Calcium signalling in bacteria. J Bacteriol (1996) 1.70
Is walking sufficient exercise for health? Sports Med (1993) 1.54
Intravenous magnesium sulfate as an adjunct in the treatment of acute asthma. Chest (1995) 1.53
Excision of the En/Spm transposable element of Zea mays requires two element-encoded proteins. EMBO J (1990) 1.53
Northern Ireland General Surgery Handover Study: surgical trainees' assessment of current practice. Surgeon (2009) 1.48
Increased neurologic complications associated with postoperative epidural analgesia after tibial fracture fixation. Am J Orthop (Belle Mead NJ) (1997) 1.42
Using functional data analysis to summarise and interpret lactate curves. Comput Biol Med (2006) 1.41
Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C. Cancer Res (1994) 1.41
Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy. Oncogene (2011) 1.38
Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells. Cancer Res (2001) 1.38
Novel exercise protocol suitable for use on a treadmill or a bicycle ergometer. Br Heart J (1990) 1.36
Effect of socioeconomic status on objectively measured physical activity. Arch Dis Child (2005) 1.33
Signal transduction and cellular radiation responses. Radiat Res (2000) 1.32
Comparison of MADS box gene expression in developing male and female flowers of the dioecious plant white campion. Plant Cell (1994) 1.31
The proteasome inhibitor bortezomib promotes mitochondrial injury and apoptosis induced by the small molecule Bcl-2 inhibitor HA14-1 in multiple myeloma cells. Leukemia (2003) 1.30
Dopamine transporter immunoreactivity in rat brain. J Comp Neurol (1995) 1.23
Isolation and characterization of X chromosome-derived DNA sequences from a dioecious plant Melandrium album. Chromosome Res (1997) 1.23
Divergent effects of bryostatin 1 and phorbol myristate acetate on cell cycle arrest and maturation in human myelomonocytic leukemia cells (U937). Differentiation (1998) 1.22
Synergistic interactions between MEK1/2 and histone deacetylase inhibitors in BCR/ABL+ human leukemia cells. Leukemia (2005) 1.21
Increases in submaximal cycling efficiency mediated by altitude acclimatization. J Appl Physiol (1985) (2000) 1.21
The combination of a novel stimulatory element in the first exon of the maize Shrunken-1 gene with the following intron 1 enhances reporter gene expression up to 1000-fold. Plant Mol Biol (1991) 1.20
Abstinence from cocaine reduces high-risk responses on a gambling task. Neuropsychopharmacology (2000) 1.20
Dietzia natronolimnaios sp. nov., a new member of the genus Dietzia isolated from an east African soda lake. Extremophiles (1998) 1.19
Electron spin resonance characterization of the NAD(P)H oxidase in vascular smooth muscle cells. Free Radic Biol Med (2001) 1.19
Synergistic induction of mitochondrial damage and apoptosis in human leukemia cells by flavopiridol and the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA). Leukemia (2002) 1.14
Abnormal gastric emptying in primary anorexia nervosa. Br J Psychiatry (1981) 1.14
Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles. J Med Chem (2000) 1.13
Coordinate regulation of stress- and mitogen-activated protein kinases in the apoptotic actions of ceramide and sphingosine. Mol Pharmacol (1997) 1.13
Ceramide and the induction of apoptosis. Clin Cancer Res (1996) 1.12
Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways. Oncogene (2001) 1.10
G1 cell cycle arrest and apoptosis are induced in NIH 3T3 cells by KN-93, an inhibitor of CaMK-II (the multifunctional Ca2+/CaM kinase). Cell Growth Differ (1995) 1.10
Pharmacologic interruption of the mitogen-activated extracellular-regulated kinase/mitogen-activated protein kinase signal transduction pathway: potential role in promoting cytotoxic drug action. Clin Cancer Res (2001) 1.09
Effect of plasma triglyceride concentrations on the accuracy of immunoturbidimetric assays of apolipoprotein B. Clin Chem (1991) 1.08
The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in human leukemia cells (U937) through the mitochondrial rather than the receptor-mediated pathway. Cell Death Differ (2001) 1.07
Lower limb blocks following general anaesthesia. Anaesthesia (2003) 1.06
Primary mesenchymal chondrosarcoma of the cerebrum. Report of a case. J Neurosurg (1966) 1.06
Cardiovascular effects of training for a marathon run in unfit middle aged men. Br Med J (Clin Res Ed) (1987) 1.06
MEK inhibitors potentiate dexamethasone lethality in acute lymphoblastic leukemia cells through the pro-apoptotic molecule BIM. Leukemia (2009) 1.05
A quantitative study of enteric endocrine cells in celiac sprue. J Pediatr Gastroenterol Nutr (1984) 1.04
A prospective study of cytomegalovirus infection in pregnancy. I. Laboratory evidence of congenital infection following maternal primary and reactivated infection. J Infect (1981) 1.03
Isolation and characterization of an anthracycline-resistant human leukemic cell line. Cancer Res (1985) 1.03
Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression. Hepatology (2001) 1.03
Identification and isolation of a putative permease gene in the quinic acid utilization (QUT) gene cluster of Aspergillus nidulans. Curr Genet (1987) 1.03
The MEK inhibitor PD184352 enhances BMS-214662-induced apoptosis in CD34+ CML stem/progenitor cells. Leukemia (2011) 1.01
Bacillus cereus endogenous panophthalmitis. Arch Ophthalmol (1979) 1.00
Identification of phosphoproteins in Escherichia coli. Mol Microbiol (1995) 0.97
Induction of differentiation and growth arrest associated with nascent (nonoligosomal) DNA fragmentation and reduced c-myc expression in MCF-7 human breast tumor cells after continuous exposure to a sublethal concentration of doxorubicin. Cell Growth Differ (1994) 0.97
Acute rheumatic fever and rheumatic heart disease on the Navajo reservation, 1962-77. Public Health Rep (1980) 0.97
Herpetiform cutaneous metastases from transitional cell carcinoma of the urinary bladder: immunohistochemical analysis. J Clin Pathol (2006) 0.95
Effects of interferon on differentiation of normal and tumor cells. Pharmacol Ther (1985) 0.95
Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling. Mol Pharmacol (1998) 0.95
Evidence of a functional role for the cyclin-dependent kinase inhibitor p21(WAF1/CIP1/MDA6) in the reciprocal regulation of PKC activator-induced apoptosis and differentation in human myelomonocytic leukemia cells. Exp Cell Res (1998) 0.95
Isolation and characterization of a deoxycytidine kinase-deficient human promyelocytic leukemic cell line highly resistant to 1-beta-D- arabinofuranosylcytosine. Cancer Res (1984) 0.95
Physiological determinants of climbing-specific finger endurance and sport rock climbing performance. J Sports Sci (2007) 0.95
Keratoconjunctivitis artefacta. Br J Ophthalmol (1982) 0.94
Protein kinase C targeting in antineoplastic treatment strategies. Invest New Drugs (1999) 0.94
Is nutritional status endangered by virtually no extra intake during pregnancy? Lancet (1985) 0.94
Effects of antisense p21 (WAF1/CIP1/MDA6) expression on the induction of differentiation and drug-mediated apoptosis in human myeloid leukemia cells (HL-60). Leukemia (1997) 0.93
A topographic representation of auditory space in the external nucleus of the inferior colliculus of the guinea-pig. Brain Res (1992) 0.93
Performance at altitude and angiotensin I-converting enzyme genotype. Eur J Appl Physiol (2004) 0.93
Plasticity in the tectum of Xenopus laevis: binocular maps. Prog Neurobiol (1999) 0.93
Uniformity, specificity and variability of corticocortical connectivity. Philos Trans R Soc Lond B Biol Sci (2000) 0.92
Exercise. BMJ (1991) 0.92
Initial aerobic power does not alter muscle metabolic adaptations to short-term training. Am J Physiol (1999) 0.92
Symptomatic local anaesthetic toxicity and plasma ropivacaine concentrations after transversus abdominis plane block for Caesarean section. Br J Anaesth (2013) 0.91
Effect of pharmacologic manipulation of protein kinase C by phorbol dibutyrate and bryostatin 1 on the clonogenic response of human granulocyte-macrophage progenitors to recombinant GM-CSF. Br J Haematol (1991) 0.91
Induction of apoptosis and potentiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells. J Biol Chem (1996) 0.91
Comparison of synthetic psoralen derivatives and 8-MOP in the inhibition of lymphocyte proliferation. Ann N Y Acad Sci (1985) 0.90
Brain imaging studies of cocaine abuse: implications for medication development. Crit Rev Neurobiol (1999) 0.90
Dopamine transporter immunohistochemistry in median eminence, amygdala, and other areas of the rat brain. Synapse (1996) 0.89
Enhancement of 1-beta-D-arabinofuranosylcytosine accumulation within L1210 cells and increased cytotoxicity following thymidine exposure. Cancer Res (1980) 0.89
Sequence-dependent potentiation of paclitaxel-mediated apoptosis in human leukemia cells by inhibitors of the mitogen-activated protein kinase kinase/mitogen-activated protein kinase pathway. Mol Pharmacol (2001) 0.89
Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells. J Biol Chem (1994) 0.89
Loss of the bcl-2 phosphorylation loop domain increases resistance of human leukemia cells (U937) to paclitaxel-mediated mitochondrial dysfunction and apoptosis. Biochem Biophys Res Commun (1999) 0.89
Rapid eye movements to a virtual target are biased by illusory context in the Poggendorff figure. Exp Brain Res (2015) 0.89
Increases in muscle MCT are associated with reductions in muscle lactate after a single exercise session in humans. Am J Physiol Endocrinol Metab (2002) 0.88
A novel assay for the measurement of Raf-1 kinase activity. Oncogene (2000) 0.88
Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation. Leukemia (2004) 0.88
Role of protein kinase C in phosphorylation of vinculin in adriamycin-resistant HL-60 leukemia cells. Cancer Res (1988) 0.88
Downregulation in muscle Na(+)-K(+)-ATPase following a 21-day expedition to 6,194 m. J Appl Physiol (1985) (2000) 0.88
Quinolones and multiresistant Plasmodium falciparum. Lancet (1988) 0.88
On variability in the density of corticocortical and thalamocortical connections. Philos Trans R Soc Lond B Biol Sci (2000) 0.88
Differences between multisite postmortem ethanol concentrations as related to agonal events. J Forensic Sci (1990) 0.88
Ocular migration and the metamorphic and postmetamorphic maturation of the retinotectal system in Xenopus laevis: an autoradiographic and morphometric study. J Embryol Exp Morphol (1986) 0.87