Published in Neuropsychopharmacology on March 03, 2016
HCN Channel Targets for Novel Antidepressant Treatment. Neurotherapeutics (2017) 0.79
Reciprocal Catecholamine Changes during Opiate Exposure and Withdrawal. Neuropsychopharmacology (2016) 0.76
Dopaminergic dynamics underlying sex-specific cocaine reward. Nat Commun (2017) 0.75
Chronic ethanol exposure increases inhibition of optically targeted phasic dopamine release in the nucleus accumbens core and medial shell ex vivo. Mol Cell Neurosci (2017) 0.75
Binge-like sucrose consumption reduces the dendritic length and complexity of principal neurons in the adolescent rat basolateral amygdala. PLoS One (2017) 0.75
A neural substrate of prediction and reward. Science (1997) 31.30
Neurocircuitry of addiction. Neuropsychopharmacology (2010) 14.22
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell (1998) 12.66
Neural mechanisms of addiction: the role of reward-related learning and memory. Annu Rev Neurosci (2006) 12.37
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci U S A (1988) 11.96
Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci (1998) 9.88
Getting formal with dopamine and reward. Neuron (2002) 9.83
Stress and the brain: from adaptation to disease. Nat Rev Neurosci (2005) 9.48
Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science (2009) 8.76
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature (1996) 7.26
Molecular basis of long-term plasticity underlying addiction. Nat Rev Neurosci (2001) 6.86
Subsecond dopamine release promotes cocaine seeking. Nature (2003) 6.53
Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. Brain Res Rev (2007) 6.36
The hippocampal-VTA loop: controlling the entry of information into long-term memory. Neuron (2005) 6.33
Lateral habenula as a source of negative reward signals in dopamine neurons. Nature (2007) 6.32
Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature (1998) 6.27
Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons. Neuron (2003) 6.19
Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. Neuron (2008) 5.65
Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons. Nature (2001) 5.65
Uniform inhibition of dopamine neurons in the ventral tegmental area by aversive stimuli. Science (2004) 5.62
Is there a common molecular pathway for addiction? Nat Neurosci (2005) 5.43
A role for lateral hypothalamic orexin neurons in reward seeking. Nature (2005) 5.41
Opioids excite dopamine neurons by hyperpolarization of local interneurons. J Neurosci (1992) 5.27
Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies. Psychopharmacology (Berl) (2000) 5.19
Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium. J Neurosci (1993) 4.90
Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission. Nat Neurosci (2003) 4.84
Behavioral dopamine signals. Trends Neurosci (2007) 4.79
A role for brain stress systems in addiction. Neuron (2008) 4.71
Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: an immunohistochemical study. Neuroendocrinology (1983) 4.67
Input-specific control of reward and aversion in the ventral tegmental area. Nature (2012) 4.60
The control of firing pattern in nigral dopamine neurons: burst firing. J Neurosci (1984) 4.52
The psychology and neurobiology of addiction: an incentive-sensitization view. Addiction (2000) 4.48
Brain dopamine and reward. Annu Rev Psychol (1989) 4.41
Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine. Neuron (2006) 4.39
Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse. J Comp Neurol (2000) 4.17
Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors. Nature (2005) 4.15
Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli. Proc Natl Acad Sci U S A (2009) 4.15
Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. Proc Natl Acad Sci U S A (1998) 3.99
The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons? J Physiol (2006) 3.97
Dopamine neurons encode the better option in rats deciding between differently delayed or sized rewards. Nat Neurosci (2007) 3.96
Behavioural assessment of drug reinforcement and addictive features in rodents: an overview. Addict Biol (2006) 3.94
Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli. Neuron (2011) 3.89
Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas. Neuron (2002) 3.78
Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro. J Neurosci (1989) 3.66
Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses. J Neurosci (2003) 3.64
The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes. Neuropsychopharmacology (2004) 3.51
Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science (1989) 3.47
Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate. J Neurosci (2010) 3.47
Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annu Rev Physiol (1995) 3.37
A neuronal nicotinic acetylcholine receptor subunit (alpha 7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX. Neuron (1990) 3.34
Brain circuitry and the reinstatement of cocaine-seeking behavior. Psychopharmacology (Berl) (2003) 3.24
Disruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behavior. Proc Natl Acad Sci U S A (2009) 3.15
Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature (2012) 3.15
Intracellular and extracellular electrophysiology of nigral dopaminergic neurons--1. Identification and characterization. Neuroscience (1983) 3.09
The brain reward circuitry in mood disorders. Nat Rev Neurosci (2013) 3.08
Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei. J Neurosci (2001) 3.05
Nicotine activates and desensitizes midbrain dopamine neurons. Nature (1997) 3.02
Dopaminergic neurons inhibit striatal output through non-canonical release of GABA. Nature (2012) 2.99
The control of firing pattern in nigral dopamine neurons: single spike firing. J Neurosci (1984) 2.99
Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area. Brain Res (1994) 2.95
Projections from the rat prefrontal cortex to the ventral tegmental area: target specificity in the synaptic associations with mesoaccumbens and mesocortical neurons. J Neurosci (2000) 2.91
Distinct extended amygdala circuits for divergent motivational states. Nature (2013) 2.88
Dopamine neurons modulate neural encoding and expression of depression-related behaviour. Nature (2012) 2.88
Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior. J Neurosci (2004) 2.87
Repeated cocaine exposure in vivo facilitates LTP induction in midbrain dopamine neurons. Nature (2005) 2.84
Direct involvement of orexinergic systems in the activation of the mesolimbic dopamine pathway and related behaviors induced by morphine. J Neurosci (2006) 2.84
Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter. J Neurosci (1998) 2.81
Corticotropin-releasing factor requires CRF binding protein to potentiate NMDA receptors via CRF receptor 2 in dopamine neurons. Neuron (2003) 2.81
Properties and opioid inhibition of mesolimbic dopamine neurons vary according to target location. J Neurosci (2006) 2.80
Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants. J Pharmacol Exp Ther (1993) 2.79
Nicotine maintains robust self-administration in rats on a limited-access schedule. Psychopharmacology (Berl) (1989) 2.78
Cocaine experience establishes control of midbrain glutamate and dopamine by corticotropin-releasing factor: a role in stress-induced relapse to drug seeking. J Neurosci (2005) 2.76
Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors. Neuron (2006) 2.69
Cellular and synaptic mechanisms of nicotine addiction. J Neurobiol (2002) 2.68
The neurobiology of nicotine addiction: bridging the gap from molecules to behaviour. Nat Rev Neurosci (2004) 2.53
Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration. J Neurosci (2008) 2.52
How addictive drugs disrupt presynaptic dopamine neurotransmission. Neuron (2011) 2.50
Excitation of ventral tegmental area dopaminergic and nondopaminergic neurons by orexins/hypocretins. J Neurosci (2003) 2.43
Pathophysiological basis of vulnerability to drug abuse: role of an interaction between stress, glucocorticoids, and dopaminergic neurons. Annu Rev Pharmacol Toxicol (1996) 2.43
Glutamate receptors on dopamine neurons control the persistence of cocaine seeking. Neuron (2008) 2.37
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. Hum Mol Genet (2009) 2.35
Structural and functional diversity of native brain neuronal nicotinic receptors. Biochem Pharmacol (2009) 2.33
The orexin system regulates alcohol-seeking in rats. Br J Pharmacol (2006) 2.30
Kappa opioids selectively control dopaminergic neurons projecting to the prefrontal cortex. Proc Natl Acad Sci U S A (2006) 2.29
Midbrain dopamine neurons: projection target determines action potential duration and dopamine D(2) receptor inhibition. J Neurosci (2008) 2.28
Anatomical substrates of orexin-dopamine interactions: lateral hypothalamic projections to the ventral tegmental area. Neuroscience (2002) 2.26
Hyperpolarization-activated cation current (Ih) is an ethanol target in midbrain dopamine neurons of mice. J Neurophysiol (2005) 2.26
Nicotine addiction and nicotinic receptors: lessons from genetically modified mice. Nat Rev Neurosci (2010) 2.25
Afferents of the ventral tegmental area in the rat-anatomical substratum for integrative functions. J Comp Neurol (2005) 2.22
Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons. Neuron (2004) 2.20
Neural bases for addictive properties of benzodiazepines. Nature (2010) 2.17
Interaction between glucocorticoid hormones, stress and psychostimulant drugs. Eur J Neurosci (2002) 2.16
Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area. Brain Res (1985) 2.11
Ethanol directly excites dopaminergic ventral tegmental area reward neurons. Alcohol Clin Exp Res (1999) 2.08
The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacol Ther (2004) 2.08
Role of lateral hypothalamic orexin neurons in reward processing and addiction. Neuropharmacology (2008) 2.06
Burst firing in dopamine neurons induced by N-methyl-D-aspartate: role of electrogenic sodium pump. Science (1992) 2.02
Activation of ventral tegmental area cells by the bed nucleus of the stria terminalis: a novel excitatory amino acid input to midbrain dopamine neurons. J Neurosci (2002) 2.00
The neurobiology of addiction: a neuroadaptational view relevant for diagnosis. Addiction (2006) 1.99
Preferential enhancement of dopamine transmission within the nucleus accumbens shell by cocaine is attributable to a direct increase in phasic dopamine release events. J Neurosci (2008) 1.97