Published in Genome Res on September 01, 2012
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Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders. Nat Neurosci (2016) 1.78
Transcriptome analysis of human tissues and cell lines reveals one dominant transcript per gene. Genome Biol (2013) 1.75
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Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes. Genome Biol (2014) 1.66
Enhancer-promoter interactions are encoded by complex genomic signatures on looping chromatin. Nat Genet (2016) 1.64
Computational approaches to identify functional genetic variants in cancer genomes. Nat Methods (2013) 1.64
Long Noncoding RNAs in Cancer Pathways. Cancer Cell (2016) 1.63
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Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer. Nat Genet (2016) 1.48
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The Landscape of long noncoding RNA classification. Trends Genet (2015) 1.47
Spatial genomic heterogeneity within localized, multifocal prostate cancer. Nat Genet (2015) 1.47
Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor. EMBO J (2013) 1.46
Promoter-like epigenetic signatures in exons displaying cell type-specific splicing. Genome Biol (2015) 1.46
DECKO: Single-oligo, dual-CRISPR deletion of genomic elements including long non-coding RNAs. BMC Genomics (2015) 1.45
Recurrent somatic mutations in regulatory regions of human cancer genomes. Nat Genet (2015) 1.45
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The genetic architecture of type 2 diabetes. Nature (2016) 1.43
Fast, scalable prediction of deleterious noncoding variants from functional and population genomic data. Nat Genet (2017) 1.42
Chromatin signatures at transcriptional start sites separate two equally populated yet distinct classes of intergenic long noncoding RNAs. Genome Biol (2013) 1.41
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Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism. Proc Natl Acad Sci U S A (2014) 1.40
Coordinated international action to accelerate genome-to-phenome with FAANG, the Functional Annotation of Animal Genomes project. Genome Biol (2015) 1.40
Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth. Nat Cell Biol (2015) 1.39
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FunSeq2: a framework for prioritizing noncoding regulatory variants in cancer. Genome Biol (2014) 1.36
Finding the active genes in deep RNA-seq gene expression studies. BMC Genomics (2013) 1.35
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Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution. Science (2014) 1.34
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The Pfam protein families database. Nucleic Acids Res (2009) 37.98
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Automated generation of heuristics for biological sequence comparison. BMC Bioinformatics (2005) 24.54
Aligning multiple genomic sequences with the threaded blockset aligner. Genome Res (2004) 24.52
International network of cancer genome projects. Nature (2010) 20.35
Landscape of transcription in human cells. Nature (2012) 20.18
Locating proteins in the cell using TargetP, SignalP and related tools. Nat Protoc (2007) 19.50
RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science (2007) 18.59
Reorganizing the protein space at the Universal Protein Resource (UniProt). Nucleic Acids Res (2011) 18.50
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Antisense transcription in the mammalian transcriptome. Science (2005) 15.69
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AceView: a comprehensive cDNA-supported gene and transcripts annotation. Genome Biol (2006) 7.52
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Rfam: Wikipedia, clans and the "decimal" release. Nucleic Acids Res (2010) 6.58
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Improving the accuracy of transmembrane protein topology prediction using evolutionary information. Bioinformatics (2007) 5.68
Lineage-specific biology revealed by a finished genome assembly of the mouse. PLoS Biol (2009) 5.45
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PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions. Bioinformatics (2011) 4.50
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Targeted RNA sequencing reveals the deep complexity of the human transcriptome. Nat Biotechnol (2011) 4.18
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Pseudogenes in the ENCODE regions: consensus annotation, analysis of transcription, and evolution. Genome Res (2007) 3.82
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Genome-wide computational identification and manual annotation of human long noncoding RNA genes. RNA (2010) 2.85
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Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. Genome Biol (2010) 2.12
firestar--prediction of functionally important residues using structural templates and alignment reliability. Nucleic Acids Res (2007) 1.91
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CAGE (cap analysis of gene expression): a protocol for the detection of promoter and transcriptional networks. Methods Mol Biol (2012) 1.50
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A transcribed pseudogene of MYLK promotes cell proliferation. FASEB J (2011) 1.37
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