Published in Nature on March 23, 2011
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Regulation of nucleosome dynamics by histone modifications. Nat Struct Mol Biol (2013) 2.71
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level. Science (2013) 2.71
Passive and active DNA methylation and the interplay with genetic variation in gene regulation. Elife (2013) 2.70
Large-scale discovery of enhancers from human heart tissue. Nat Genet (2011) 2.70
Transcriptional and epigenetic dynamics during specification of human embryonic stem cells. Cell (2013) 2.64
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Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. Am J Hum Genet (2014) 2.53
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Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence. J Neurosci (2012) 2.46
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A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet (2012) 2.45
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BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature (2015) 2.15
Polycomb-repressed genes have permissive enhancers that initiate reprogramming. Cell (2011) 2.14
Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits. Genome Res (2013) 2.14
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eRNAs promote transcription by establishing chromatin accessibility at defined genomic loci. Mol Cell (2013) 2.12
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Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis. Nat Immunol (2011) 1.89
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TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res (2003) 29.26
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Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
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A chromatin landmark and transcription initiation at most promoters in human cells. Cell (2007) 23.41
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet (2008) 20.73
A global map of p53 transcription-factor binding sites in the human genome. Cell (2006) 20.65
Mapping the genetic architecture of gene expression in human liver. PLoS Biol (2008) 19.44
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Genomic maps and comparative analysis of histone modifications in human and mouse. Cell (2005) 18.96
Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature (2010) 16.86
Widespread transcription at neuronal activity-regulated enhancers. Nature (2010) 16.52
Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs. Cell (2004) 16.15
Direct multiplexed measurement of gene expression with color-coded probe pairs. Nat Biotechnol (2008) 15.90
CTCF: master weaver of the genome. Cell (2009) 15.09
Transcriptome genetics using second generation sequencing in a Caucasian population. Nature (2010) 14.85
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Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions. Nature (2008) 10.95
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet (2010) 9.90
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Variation in transcription factor binding among humans. Science (2010) 9.33
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Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet (2008) 6.97
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
Genomic views of distant-acting enhancers. Nature (2009) 6.27
A large fraction of extragenic RNA pol II transcription sites overlap enhancers. PLoS Biol (2010) 6.01
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Transposable elements have rewired the core regulatory network of human embryonic stem cells. Nat Genet (2010) 5.26
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Sequencing newly replicated DNA reveals widespread plasticity in human replication timing. Proc Natl Acad Sci U S A (2009) 4.76
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Histone variants--ancient wrap artists of the epigenome. Nat Rev Mol Cell Biol (2010) 4.45
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