Published in Breast Cancer Res on September 12, 2012
Nitric oxide and cancer: a review. World J Surg Oncol (2013) 1.22
Inhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer. Breast Cancer Res (2015) 1.04
Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression. Proc Natl Acad Sci U S A (2014) 1.01
Molecular pathways: inflammation-associated nitric-oxide production as a cancer-supporting redox mechanism and a potential therapeutic target. Clin Cancer Res (2013) 0.97
The breast cancer oncogene EMSY represses transcription of antimetastatic microRNA miR-31. Mol Cell (2014) 0.97
Mechanism-based triarylphosphine-ester probes for capture of endogenous RSNOs. J Am Chem Soc (2013) 0.96
Linking signaling pathways to transcriptional programs in breast cancer. Genome Res (2014) 0.95
Cancer cell metabolism and the modulating effects of nitric oxide. Free Radic Biol Med (2014) 0.90
Endogenously produced nitric oxide mitigates sensitivity of melanoma cells to cisplatin. Proc Natl Acad Sci U S A (2012) 0.90
Signaling and stress: The redox landscape in NOS2 biology. Free Radic Biol Med (2015) 0.82
NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay. Cancer Res (2015) 0.81
P-cadherin and the journey to cancer metastasis. Mol Cancer (2015) 0.80
The diatom-derived aldehyde decadienal affects life cycle transition in the ascidian Ciona intestinalis through nitric oxide/ERK signalling. Open Biol (2015) 0.79
INPP4B is an oncogenic regulator in human colon cancer. Oncogene (2015) 0.78
Decreased tumorigenesis in mice with a Kras point mutation at C118. Nat Commun (2014) 0.77
Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications. Cancer Res (2015) 0.77
Biological signaling by small inorganic molecules. Coord Chem Rev (2016) 0.77
S-Nitrosation Mediates Multiple Pathways That Lead to Tumor Progression in Estrogen Receptor-Negative Breast Cancer. For Immunopathol Dis Therap (2012) 0.76
PC-TraFF: identification of potentially collaborating transcription factors using pointwise mutual information. BMC Bioinformatics (2015) 0.76
S-Nitrosylation in Organs of Mice Exposed to Low or High Doses of γ-Rays: The Modulating Effect of Iodine Contrast Agent at a Low Radiation Dose. Proteomes (2015) 0.75
Nitric oxide: What's new to NO? Am J Physiol Cell Physiol (2016) 0.75
S-nitrosylation of Ras in breast cancer. Breast Cancer Res (2012) 0.75
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A (2001) 71.82
Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem J (2000) 6.55
The biotin switch method for the detection of S-nitrosylated proteins. Sci STKE (2001) 6.09
Basal-like breast cancer: a critical review. J Clin Oncol (2008) 5.64
Protein kinase C alpha activates RAF-1 by direct phosphorylation. Nature (1993) 5.23
Triple negative tumours: a critical review. Histopathology (2008) 4.94
Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene (2006) 4.85
Metalloproteinases: role in breast carcinogenesis, invasion and metastasis. Breast Cancer Res (2000) 3.41
"NONOates" (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms. Methods Enzymol (1996) 3.34
The role of nitric oxide in tumour progression. Nat Rev Cancer (2006) 3.08
The biology of the Ets1 proto-oncogene. Mol Cancer (2003) 2.88
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2. Mol Cell Biol (1996) 2.79
The chemical biology of nitric oxide: implications in cellular signaling. Free Radic Biol Med (2008) 2.72
A clinically relevant gene signature in triple negative and basal-like breast cancer. Breast Cancer Res (2011) 2.26
S-nitrosylation from GSNOR deficiency impairs DNA repair and promotes hepatocarcinogenesis. Sci Transl Med (2010) 2.13
A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction. J Biol Chem (1997) 2.08
Nitric oxide and redox mechanisms in the immune response. J Leukoc Biol (2011) 1.97
Reaction kinetics for nitrosation of cysteine and glutathione in aerobic nitric oxide solutions at neutral pH. Insights into the fate and physiological effects of intermediates generated in the NO/O2 reaction. Chem Res Toxicol (1995) 1.90
Cathepsin B inhibition limits bone metastasis in breast cancer. Cancer Res (2012) 1.89
Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide. Proc Natl Acad Sci U S A (2004) 1.87
Ras activation in human breast cancer. Breast Cancer Res Treat (2000) 1.83
Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell (2011) 1.77
Involvement of cathepsins in the invasion, metastasis and proliferation of cancer cells. J Med Invest (2005) 1.55
Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway. Oncogene (2002) 1.53
Dislodgment and accelerated degradation of Ras. Biochemistry (1998) 1.53
Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients. J Clin Invest (2010) 1.52
Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival. Clin Cancer Res (2000) 1.52
Conserved mechanisms of Ras regulation of evolutionary related transcription factors, Ets1 and Pointed P2. Oncogene (1997) 1.41
Inflammation and IGF-I activate the Akt pathway in breast cancer. Int J Cancer (2007) 1.38
Expression of the transcription factor Ets-1 is an independent prognostic marker for relapse-free survival in breast cancer. Oncogene (2002) 1.34
Ets-1 regulates angiogenesis by inducing the expression of urokinase-type plasminogen activator and matrix metalloproteinase-1 and the migration of vascular endothelial cells. J Cell Physiol (1996) 1.32
Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways. Proc Natl Acad Sci U S A (2007) 1.26
Overexpression of the Ets-1 transcription factor in human breast cancer. Br J Cancer (2004) 1.20
Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway. Cancer Res (2007) 1.19
S-nitrosylation at cysteine 498 of c-Src tyrosine kinase regulates nitric oxide-mediated cell invasion. J Biol Chem (2009) 1.17
The Ets-1 transcription factor is up-regulated together with MMP 1 and MMP 9 in the stroma of pre-invasive breast cancer. J Pathol (2001) 1.15
Molecular mechanisms for discrete nitric oxide levels in cancer. Nitric Oxide (2008) 1.14
AlphaB-crystallin: a novel marker of invasive basal-like and metaplastic breast carcinomas. Ann Diagn Pathol (2007) 1.13
The Ets-1 transcription factor is involved in the development and invasion of malignant melanoma. Cell Mol Life Sci (2004) 1.11
Inhibition of vascular endothelial growth factor-induced endothelial cell migration by ETS1 antisense oligonucleotides. Cancer Res (1997) 1.07
Defining ETS transcription regulatory networks and their contribution to breast cancer progression. J Cell Biochem (2007) 1.07
Monitoring reactions of nitric oxide with peptides and proteins by electrospray ionization-mass spectrometry. J Biol Chem (1995) 1.05
The transcription factor Ets-1 in breast cancer. Front Biosci (2005) 1.03
Recruitment and activation of Raf-1 kinase by nitric oxide-activated Ras. Biochemistry (2000) 1.03
Ets-1 expression promotes epithelial cell transformation by inducing migration, invasion and anchorage-independent growth. Oncogene (2005) 1.02
Clinical significance of matrix metalloproteinase-7 and Ets-1 gene expression in patients with lung cancer. J Surg Res (2001) 0.95
Activation of epidermal growth factor receptor and its downstream signaling pathway by nitric oxide in response to ionizing radiation. Mol Cancer Res (2008) 0.95
Protein kinase Calpha regulates Ets1 transcriptional activity in invasive breast cancer cells. Int J Oncol (2003) 0.94
S-nitrosoglutathione reductase in human lung cancer. Am J Respir Cell Mol Biol (2012) 0.94
Nitric oxide and protein phosphatase 2A provide novel therapeutic opportunities in ER-negative breast cancer. Trends Pharmacol Sci (2011) 0.94
Lack of evidence for KRAS oncogenic mutations in triple-negative breast cancer. BMC Cancer (2010) 0.93
Ets1 is an effector of protein kinase Calpha in cancer cells. Oncogene (2005) 0.91
Ets-1 proto-oncogene as a potential predictor for poor prognosis of lung adenocarcinoma. Tohoku J Exp Med (2007) 0.90
NO news is not necessarily good news in cancer. Curr Cancer Drug Targets (2005) 0.88
Regulation of alphaB-crystallin gene expression by the transcription factor Ets1 in breast cancer. Breast Cancer Res Treat (2009) 0.87
NO to breast: when, why and why not? Curr Pharm Des (2010) 0.83
Inactivation of Ets 1 transcription factor by a specific decoy strategy reduces rat C6 glioma cell proliferation and mmp-9 expression. Int J Mol Med (2005) 0.83
Study of the topographic distribution of ets-1 protein expression in invasive breast carcinomas in relation to tumor phenotype. Cancer Detect Prev (2006) 0.83
Ets-1 triggers and orchestrates the malignant phenotype of mammary cancer cells within their matrix environment. J Cell Physiol (2008) 0.81
A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A (2006) 40.09
MicroRNA expression, survival, and response to interferon in liver cancer. N Engl J Med (2009) 6.13
Tumor immunobiological differences in prostate cancer between African-American and European-American men. Cancer Res (2008) 3.39
The emerging biology of the nitrite anion. Nat Chem Biol (2005) 2.88
The chemical biology of nitric oxide: implications in cellular signaling. Free Radic Biol Med (2008) 2.72
Reprogramming of miRNA networks in cancer and leukemia. Genome Res (2010) 2.65
Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations. Am J Physiol Regul Integr Comp Physiol (2004) 2.61
Retracted FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer. J Clin Invest (2011) 2.44
CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1. J Biol Chem (2006) 2.23
A stromal gene signature associated with inflammatory breast cancer. Int J Cancer (2008) 2.18
Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner. Proc Natl Acad Sci U S A (2005) 2.17
Increasing survival of ischemic tissue by targeting CD47. Circ Res (2007) 2.16
Nitric oxide-induced cellular stress and p53 activation in chronic inflammation. Proc Natl Acad Sci U S A (2002) 2.04
Nitric oxide and redox mechanisms in the immune response. J Leukoc Biol (2011) 1.97
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis. J Clin Invest (2013) 1.89
Association of breast cancer outcome with status of p53 and MDM2 SNP309. J Natl Cancer Inst (2006) 1.88
Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide. Proc Natl Acad Sci U S A (2004) 1.87
Expression of microRNAs and protein-coding genes associated with perineural invasion in prostate cancer. Prostate (2008) 1.86
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system. Proc Natl Acad Sci U S A (2003) 1.78
Positive inotropic and lusitropic effects of HNO/NO- in failing hearts: independence from beta-adrenergic signaling. Proc Natl Acad Sci U S A (2003) 1.76
Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling. Blood (2007) 1.73
Differences in the tumor microenvironment between African-American and European-American breast cancer patients. PLoS One (2009) 1.72
A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression. PLoS Genet (2011) 1.60
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. J Am Coll Cardiol (2010) 1.56
Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling. Circ Res (2006) 1.56
Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide-mediated vascular smooth muscle relaxation. Blood (2006) 1.56
Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1. Proc Natl Acad Sci U S A (2005) 1.55
Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis. PLoS Genet (2007) 1.55
Protein nitration is mediated by heme and free metals through Fenton-type chemistry: an alternative to the NO/O2- reaction. Proc Natl Acad Sci U S A (2002) 1.53
Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients. J Clin Invest (2010) 1.52
Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species. Chem Res Toxicol (2012) 1.51
Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling. Sci Transl Med (2009) 1.47
The reduction potential of nitric oxide (NO) and its importance to NO biochemistry. Proc Natl Acad Sci U S A (2002) 1.45
Thrombospondin-1 antagonizes nitric oxide-stimulated vascular smooth muscle cell responses. Cardiovasc Res (2006) 1.43
Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake. J Biol Chem (2007) 1.41
The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO. Pharmacol Ther (2006) 1.41
MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer. Nucleic Acids Res (2011) 1.39
Oxidative stress, redox, and the tumor microenvironment. Semin Radiat Oncol (2004) 1.38
Inflammation and IGF-I activate the Akt pathway in breast cancer. Int J Cancer (2007) 1.38
Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry. Carcinogenesis (2012) 1.38
The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations. Biol Chem (2004) 1.37
Focusing of nitric oxide mediated nitrosation and oxidative nitrosylation as a consequence of reaction with superoxide. Proc Natl Acad Sci U S A (2002) 1.33
The biphasic nature of nitric oxide responses in tumor biology. Antioxid Redox Signal (2006) 1.32
Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology. J Transl Med (2009) 1.31
Immunotherapeutic potential of anti-human endogenous retrovirus-K envelope protein antibodies in targeting breast tumors. J Natl Cancer Inst (2012) 1.30
Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells. Cancer Res (2008) 1.30
Nitroxyl affords thiol-sensitive myocardial protective effects akin to early preconditioning. Free Radic Biol Med (2003) 1.28
CD47 deficiency confers cell and tissue radioprotection by activation of autophagy. Autophagy (2012) 1.27
Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury. Am J Pathol (2008) 1.26
Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways. Proc Natl Acad Sci U S A (2007) 1.26
Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo. J Med Chem (2005) 1.26
Nitroxyl (HNO): chemistry, biochemistry, and pharmacology. Annu Rev Pharmacol Toxicol (2005) 1.25
Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death. Free Radic Biol Med (2011) 1.24
The physiological chemistry and biological activity of nitroxyl (HNO): the neglected, misunderstood, and enigmatic nitrogen oxide. Chem Res Toxicol (2005) 1.24
Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts. Ann Surg (2008) 1.24
Exploring SNP-SNP interactions and colon cancer risk using polymorphism interaction analysis. Int J Cancer (2006) 1.23
Superoxide fluxes limit nitric oxide-induced signaling. J Biol Chem (2006) 1.22
Mechanism of aerobic decomposition of Angeli's salt (sodium trioxodinitrate) at physiological pH. J Am Chem Soc (2005) 1.22
Physiological and pharmacological features of the novel gasotransmitter: hydrogen sulfide. Biochim Biophys Acta (2009) 1.20
Guide for the use of nitric oxide (NO) donors as probes of the chemistry of NO and related redox species in biological systems. Methods Enzymol (2002) 1.20
Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA. Breast Cancer Res Treat (2011) 1.19
Comparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity. J Pharmacol Exp Ther (2005) 1.18
Inhibition of poly(ADP-RIBOSE) polymerase (PARP) by nitric oxide and reactive nitrogen oxide species. Free Radic Biol Med (2003) 1.16
Direct real-time evaluation of nitration with green fluorescent protein in solution and within human cells reveals the impact of nitrogen dioxide vs. peroxynitrite mechanisms. Proc Natl Acad Sci U S A (2002) 1.15
Relationship between tumor DNA methylation status and patient characteristics in African-American and European-American women with breast cancer. PLoS One (2012) 1.15
The yin and yang of nitric oxide in cancer progression. Carcinogenesis (2013) 1.14
Molecular mechanisms for discrete nitric oxide levels in cancer. Nitric Oxide (2008) 1.14
Mammalian transforming growth factor beta1 activated after ingestion by Anopheles stephensi modulates mosquito immunity. Infect Immun (2003) 1.14
Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy. J Exp Med (2010) 1.12
Biological determinants of health disparities in prostate cancer. Curr Opin Oncol (2013) 1.12
A genome-wide association study of breast cancer in women of African ancestry. Hum Genet (2012) 1.11
Nitric oxide in wound-healing. Microsurgery (2005) 1.10
Interactions among genes, tumor biology and the environment in cancer health disparities: examining the evidence on a national and global scale. Carcinogenesis (2011) 1.10
Molecular pathways: toll-like receptors in the tumor microenvironment--poor prognosis or new therapeutic opportunity. Clin Cancer Res (2012) 1.09