Neural regeneration in Caenorhabditis elegans.

Insulin/IGF1 signaling inhibits age-dependent axon regeneration. Neuron (2014) 1.23

An assay to image neuronal microtubule dynamics in mice. Nat Commun (2014) 1.00

Design and implementation of in vivo imaging of neural injury responses in the adult Drosophila wing. Nat Protoc (2013) 0.98

Axon injury and regeneration in the adult Drosophila. Sci Rep (2014) 0.89

Axon regeneration in C. elegans. Curr Opin Neurobiol (2014) 0.86

A fully automated microfluidic femtosecond laser axotomy platform for nerve regeneration studies in C. elegans. PLoS One (2014) 0.83

Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans. PLoS One (2014) 0.80

Mitochondria Localize to Injured Axons to Support Regeneration. Neuron (2016) 0.78

Ion channels in regulation of neuronal regenerative activities. Transl Stroke Res (2014) 0.78

Hope on the (fruit) fly: the Drosophila wing paradigm of axon injury. Neural Regen Res (2015) 0.76

The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans. Genetics (2016) 0.76

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell (2001) 25.86

Regeneration beyond the glial scar. Nat Rev Neurosci (2004) 11.00

Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell (1985) 6.93

Glial inhibition of CNS axon regeneration. Nat Rev Neurosci (2006) 6.91

Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway. Science (2008) 6.86

The development and application of optogenetics. Annu Rev Neurosci (2011) 6.84

The neuronal microRNA system. Nat Rev Neurosci (2006) 5.38

Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS. Nat Rev Neurosci (2003) 4.60

Neurosurgery: functional regeneration after laser axotomy. Nature (2004) 4.51

Notch signaling: the core pathway and its posttranslational regulation. Dev Cell (2009) 4.49

Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury. Neuron (1999) 4.13

One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction. Nat Neurosci (1999) 3.88

Axon regeneration requires a conserved MAP kinase pathway. Science (2009) 3.48

Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury. Science (2011) 3.45

SOCS3 deletion promotes optic nerve regeneration in vivo. Neuron (2009) 3.22

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3. Nature (2011) 3.18

Calcium depletion dissociates and activates heterodimeric notch receptors. Mol Cell Biol (2000) 3.15

Spinal axon regeneration induced by elevation of cyclic AMP. Neuron (2002) 3.09

Identification and partial purification of ankyrin, the high affinity membrane attachment site for human erythrocyte spectrin. J Biol Chem (1979) 3.08

Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element. Mol Cell Biol (2006) 2.94

Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development. Cell (2005) 2.93

Microfluidic system for on-chip high-throughput whole-animal sorting and screening at subcellular resolution. Proc Natl Acad Sci U S A (2007) 2.93

Genes required for GABA function in Caenorhabditis elegans. Nature (1993) 2.87

Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation. Neuron (2002) 2.84

The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration. Cell (2009) 2.72

EFA6, a sec7 domain-containing exchange factor for ARF6, coordinates membrane recycling and actin cytoskeleton organization. EMBO J (1999) 2.63

Notch activity acts as a sensor for extracellular calcium during vertebrate left-right determination. Nature (2004) 2.63

The spectrin-based membrane skeleton and micron-scale organization of the plasma membrane. Annu Rev Cell Biol (1993) 2.62

Optical interrogation of neural circuits in Caenorhabditis elegans. Nat Methods (2009) 2.51

Disorganized microtubules underlie the formation of retraction bulbs and the failure of axonal regeneration. J Neurosci (2007) 2.51

Femtosecond laser nanoaxotomy lab-on-a-chip for in vivo nerve regeneration studies. Nat Methods (2008) 2.38

rpm-1, a conserved neuronal gene that regulates targeting and synaptogenesis in C. elegans. Neuron (2000) 2.36

Adenylyl cyclases and the interaction between calcium and cAMP signalling. Nature (1995) 2.30

Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury? Nat Rev Neurosci (2006) 2.28

The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch. Nature (1988) 2.27

Caenorhabditis elegans neuronal regeneration is influenced by life stage, ephrin signaling, and synaptic branching. Proc Natl Acad Sci U S A (2007) 2.25

Regulation of presynaptic terminal organization by C. elegans RPM-1, a putative guanine nucleotide exchanger with a RING-H2 finger domain. Neuron (2000) 2.12

The Nogo-66 receptor: focusing myelin inhibition of axon regeneration. Trends Neurosci (2003) 2.11

F-spondin: a gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension. Cell (1992) 2.05

Chondroitinase ABC promotes sprouting of intact and injured spinal systems after spinal cord injury. J Neurosci (2006) 1.99

Cyclic AMP-induced repair of zebrafish spinal circuits. Science (2004) 1.96

Axons break in animals lacking beta-spectrin. J Cell Biol (2007) 1.94

The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins. Dev Cell (2004) 1.93

PTEN inhibition to facilitate intrinsic regenerative outgrowth of adult peripheral axons. J Neurosci (2010) 1.91

Calcium and cyclic AMP promote axonal regeneration in Caenorhabditis elegans and require DLK-1 kinase. J Neurosci (2010) 1.89

The type I membrane protein EFF-1 is essential for developmental cell fusion. Dev Cell (2002) 1.87

Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages. J Biol Chem (1993) 1.86

Axon regeneration pathways identified by systematic genetic screening in C. elegans. Neuron (2011) 1.78

C. elegans RPM-1 regulates axon termination and synaptogenesis through the Rab GEF GLO-4 and the Rab GTPase GLO-1. Neuron (2007) 1.76

The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response. EMBO J (2004) 1.76

Axonal growth therapeutics: regeneration or sprouting or plasticity? Trends Neurosci (2008) 1.66

The role of the AFD neuron in C. elegans thermotaxis analyzed using femtosecond laser ablation. BMC Neurosci (2006) 1.66

Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways. Proc Natl Acad Sci U S A (2011) 1.65

Functional axonal regeneration through astrocytic scar genetically modified to digest chondroitin sulfate proteoglycans. J Neurosci (2007) 1.64

Taxol facilitates axon regeneration in the mature CNS. J Neurosci (2011) 1.62

Interaction between Notch and Hif-alpha in development and survival of Drosophila blood cells. Science (2011) 1.61

Global up-regulation of microtubule dynamics and polarity reversal during regeneration of an axon from a dendrite. Mol Biol Cell (2010) 1.55

Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans. Development (2008) 1.52

Drosophila HOPS and AP-3 complex genes are required for a Deltex-regulated activation of notch in the endosomal trafficking pathway. Dev Cell (2008) 1.51

Regulation of intrinsic neuronal properties for axon growth and regeneration. Prog Neurobiol (2006) 1.50

Impaired regenerative response of primary sensory neurons in ZPK/DLK gene-trap mice. Biochem Biophys Res Commun (2009) 1.47

Drosophila deltex mediates suppressor of Hairless-independent and late-endosomal activation of Notch signaling. Development (2004) 1.47

Spontaneous age-related neurite branching in Caenorhabditis elegans. J Neurosci (2011) 1.44

The fusogen EFF-1 controls sculpting of mechanosensory dendrites. Science (2010) 1.42

Oxidative damage to extracellular matrix and its role in human pathologies. Free Radic Biol Med (2008) 1.40

Mutations in beta-spectrin disrupt axon outgrowth and sarcomere structure. J Cell Biol (2000) 1.40

Large-scale in vivo femtosecond laser neurosurgery screen reveals small-molecule enhancer of regeneration. Proc Natl Acad Sci U S A (2010) 1.37

The making of successful axonal regeneration: genes, molecules and signal transduction pathways. Brain Res Rev (2006) 1.32

Membrane resealing in cultured rat septal neurons after neurite transection: evidence for enhancement by Ca(2+)-triggered protease activity and cytoskeletal disassembly. J Neurosci (1991) 1.31

Notch signaling inhibits axon regeneration. Neuron (2012) 1.26

Microtubule depolymerization in Caenorhabditis elegans touch receptor neurons reduces gene expression through a p38 MAPK pathway. Proc Natl Acad Sci U S A (2011) 1.25

The C. elegans peroxidasin PXN-2 is essential for embryonic morphogenesis and inhibits adult axon regeneration. Development (2010) 1.24

OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development. PLoS Biol (2008) 1.22

Axotomy induces a transient and localized elevation of the free intracellular calcium concentration to the millimolar range. J Neurophysiol (1995) 1.16

Degradation of chondroitin sulfate proteoglycans induces sprouting of intact purkinje axons in the cerebellum of the adult rat. J Neurosci (2005) 1.13

Myelin associated inhibitors: a link between injury-induced and experience-dependent plasticity. Exp Neurol (2011) 1.12

A novel ankyrin repeat-containing gene (Kank) located at 9p24 is a growth suppressor of renal cell carcinoma. J Biol Chem (2002) 1.12

Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal. J Cell Biol (2011) 1.11

MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish. Eur J Neurosci (2011) 1.10

Axonal regeneration proceeds through specific axonal fusion in transected C. elegans neurons. Dev Dyn (2011) 1.10

Spatiotemporal distribution of Ca2+ following axotomy and throughout the recovery process of cultured Aplysia neurons. Eur J Neurosci (1993) 1.09

Myeloperoxidase inactivates TIMP-1 by oxidizing its N-terminal cysteine residue: an oxidative mechanism for regulating proteolysis during inflammation. J Biol Chem (2007) 1.06

MicroRNA dysregulation following spinal cord contusion: implications for neural plasticity and repair. Neuroscience (2011) 1.05

RPM-1, a Caenorhabditis elegans protein that functions in presynaptic differentiation, negatively regulates axon outgrowth by controlling SAX-3/robo and UNC-5/UNC5 activity. J Neurosci (2008) 1.04

Sensory axon regeneration: rebuilding functional connections in the spinal cord. Trends Neurosci (2011) 1.03

The C. elegans F-spondin family protein SPON-1 maintains cell adhesion in neural and non-neural tissues. Development (2008) 1.03

Caenorhabditis elegans EFA-6 limits microtubule growth at the cell cortex. Nat Cell Biol (2010) 1.02

Calcium-assisted glass-to-glass bonding for fabrication of glass microfluidic devices. Anal Chem (2008) 1.01

Characterization of loss-of-function and gain-of-function Eph receptor tyrosine kinase signaling in C. elegans axon targeting and cell migration. Dev Biol (2006) 1.00

Regulation of neuronal growth cone filopodia by intracellular calcium. J Neurosci (1992) 0.98

Axon regeneration mechanisms: insights from C. elegans. Trends Cell Biol (2011) 0.97

Femtosecond laser nanoaxotomy properties and their effect on axonal recovery in C. elegans. Opt Express (2008) 0.97

Dicer-microRNA pathway is critical for peripheral nerve regeneration and functional recovery in vivo and regenerative axonogenesis in vitro. Exp Neurol (2011) 0.96

Calcium entry through L-type calcium channels is essential for neurite regeneration in cultured sympathetic neurons. J Neurotrauma (2004) 0.93

In vivo nanosecond laser axotomy: cavitation dynamics and vesicle transport. Opt Express (2008) 0.92

The growth factor SVH-1 regulates axon regeneration in C. elegans via the JNK MAPK cascade. Nat Neurosci (2012) 0.90

A role for cAMP in regeneration during development and after injury. Prog Brain Res (2002) 0.89

The cyclic AMP (adenosine 3',5'-phosphate) content of sciatic nerve: changes after nerve crush. Brain Res (1972) 0.87

Synaptic connections made by axons regenerating in the central nervous system of adult mammals. J Exp Biol (1990) 0.84

Roles of Drosophila deltex in Notch receptor endocytic trafficking and activation. Genes Cells (2011) 0.84

Rapid single nucleotide polymorphism mapping in C. elegans. BMC Genomics (2005) 3.57

Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex. Proc Natl Acad Sci U S A (2010) 1.51

Notch signaling inhibits axon regeneration. Neuron (2012) 1.26

Axon regeneration genes identified by RNAi screening in C. elegans. J Neurosci (2014) 0.98

Rapid and permanent neuronal inactivation in vivo via subcellular generation of reactive oxygen with the use of KillerRed. Cell Rep (2013) 0.98

Bidirectional thermotaxis in Caenorhabditis elegans is mediated by distinct sensorimotor strategies driven by the AFD thermosensory neurons. Proc Natl Acad Sci U S A (2014) 0.94

In vivo laser axotomy in C. elegans. J Vis Exp (2011) 0.93

Neuron-specific feeding RNAi in C. elegans and its use in a screen for essential genes required for GABA neuron function. PLoS Genet (2013) 0.87

Single-nucleotide polymorphism mapping. Methods Mol Biol (2006) 0.84

Science in Suzhou: establishment and function of neural circuits. EMBO Rep (2012) 0.75