Published in BMC Genomics on September 12, 2005
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Genetic screens for Caenorhabditis elegans mutants defective in left/right asymmetric neuronal fate specification. Genetics (2007) 2.48
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A strategy for direct mapping and identification of mutations by whole-genome sequencing. Genetics (2010) 2.08
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A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response. Neuron (2009) 2.01
Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans. Genes Dev (2007) 1.94
Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle. Mol Biol Cell (2007) 1.80
Whole-genome profiling of mutagenesis in Caenorhabditis elegans. Genetics (2010) 1.62
Automated screening for mutants affecting dopaminergic-neuron specification in C. elegans. Nat Methods (2008) 1.61
Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans. PLoS Genet (2010) 1.55
Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates. PLoS Genet (2009) 1.52
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Progressive degeneration of dopaminergic neurons through TRP channel-induced cell death. J Neurosci (2014) 1.43
A pre-mRNA-associating factor links endogenous siRNAs to chromatin regulation. PLoS Genet (2011) 1.42
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Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2010) 1.39
Heat avoidance is regulated by transient receptor potential (TRP) channels and a neuropeptide signaling pathway in Caenorhabditis elegans. Genetics (2011) 1.37
DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans. Genetics (2008) 1.34
Integration of metabolic and gene regulatory networks modulates the C. elegans dietary response. Cell (2013) 1.32
The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface. J Cell Biol (2012) 1.31
Symmetry breaking and polarization of the C. elegans zygote by the polarity protein PAR-2. Development (2010) 1.28
A neuronal acetylcholine receptor regulates the balance of muscle excitation and inhibition in Caenorhabditis elegans. PLoS Biol (2009) 1.27
SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans. Hum Mol Genet (2009) 1.16
A yeast two-hybrid screen for SYP-3 interactors identifies SYP-4, a component required for synaptonemal complex assembly and chiasma formation in Caenorhabditis elegans meiosis. PLoS Genet (2009) 1.10
CRA-1 uncovers a double-strand break-dependent pathway promoting the assembly of central region proteins on chromosome axes during C. elegans meiosis. PLoS Genet (2008) 1.09
The new anthelmintic tribendimidine is an L-type (levamisole and pyrantel) nicotinic acetylcholine receptor agonist. PLoS Negl Trop Dis (2009) 1.08
Interplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosis. PLoS Genet (2013) 1.07
The Caenorhabditis elegans K10C2.4 gene encodes a member of the fumarylacetoacetate hydrolase family: a Caenorhabditis elegans model of type I tyrosinemia. J Biol Chem (2008) 1.04
The C. elegans DSB-2 protein reveals a regulatory network that controls competence for meiotic DSB formation and promotes crossover assurance. PLoS Genet (2013) 1.03
CYSL-1 interacts with the O2-sensing hydroxylase EGL-9 to promote H2S-modulated hypoxia-induced behavioral plasticity in C. elegans. Neuron (2012) 1.01
SLX-1 is required for maintaining genomic integrity and promoting meiotic noncrossovers in the Caenorhabditis elegans germline. PLoS Genet (2012) 1.01
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The response of Caenorhabditis elegans to hydrogen sulfide and hydrogen cyanide. Genetics (2011) 0.98
α-Catulin CTN-1 is required for BK channel subcellular localization in C. elegans body-wall muscle cells. EMBO J (2010) 0.97
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A combinatorial regulatory signature controls terminal differentiation of the dopaminergic nervous system in C. elegans. Genes Dev (2013) 0.97
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A dominant mutation in a neuronal acetylcholine receptor subunit leads to motor neuron degeneration in Caenorhabditis elegans. J Neurosci (2010) 0.94
Single/low-copy integration of transgenes in Caenorhabditis elegans using an ultraviolet trimethylpsoralen method. BMC Biotechnol (2012) 0.94
P-type ATPase TAT-2 negatively regulates monomethyl branched-chain fatty acid mediated function in post-embryonic growth and development in C. elegans. PLoS Genet (2009) 0.94
C. elegans SWAN-1 Binds to EGL-9 and regulates HIF-1-mediated resistance to the bacterial pathogen Pseudomonas aeruginosa PAO1. PLoS Pathog (2010) 0.93
The Caenorhabditis elegans microtubule minus-end binding homolog PTRN-1 stabilizes synapses and neurites. Elife (2014) 0.93
Lipid environment modulates the development of acute tolerance to ethanol in Caenorhabditis elegans. PLoS One (2012) 0.93
Transmembrane proteins UNC-40/DCC, PTP-3/LAR, and MIG-21 control anterior-posterior neuroblast migration with left-right functional asymmetry in Caenorhabditis elegans. Genetics (2012) 0.92
Domain-specific regulation of recombination in Caenorhabditis elegans in response to temperature, age and sex. Genetics (2008) 0.92
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Nuclear cGMP-dependent kinase regulates gene expression via activity-dependent recruitment of a conserved histone deacetylase complex. PLoS Genet (2011) 0.91
Genetic and cellular characterization of Caenorhabditis elegans mutants abnormal in the regulation of many phase II enzymes. PLoS One (2010) 0.91
A novel auxiliary subunit critical to BK channel function in Caenorhabditis elegans. J Neurosci (2010) 0.91
A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans. Elife (2013) 0.91
Multigenic natural variation underlies Caenorhabditis elegans olfactory preference for the bacterial pathogen Serratia marcescens. G3 (Bethesda) (2014) 0.90
The balance between cytoplasmic and nuclear CaM kinase-1 signaling controls the operating range of noxious heat avoidance. Neuron (2014) 0.90
Genetic suppressors of Caenorhabditis elegans pha-4/FoxA identify the predicted AAA helicase ruvb-1/RuvB. Genetics (2007) 0.90
Dystrobrevin controls neurotransmitter release and muscle Ca(2+) transients by localizing BK channels in Caenorhabditis elegans. J Neurosci (2011) 0.89
Genes required for cellular UNC-6/netrin localization in Caenorhabditis elegans. Genetics (2010) 0.87
Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One (2010) 0.87
A ubiquitin E2 variant protein acts in axon termination and synaptogenesis in Caenorhabditis elegans. Genetics (2010) 0.86
Forward genetic analysis to identify determinants of dopamine signaling in Caenorhabditis elegans using swimming-induced paralysis. G3 (Bethesda) (2012) 0.86
akirin is required for diakinesis bivalent structure and synaptonemal complex disassembly at meiotic prophase I. Mol Biol Cell (2013) 0.86
Deep sequencing strategies for mapping and identifying mutations from genetic screens. Worm (2013) 0.86
Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion. J Cell Biol (2016) 0.85
A dominant mutation in mec-7/β-tubulin affects axon development and regeneration in Caenorhabditis elegans neurons. Mol Biol Cell (2012) 0.85
COMP-1 promotes competitive advantage of nematode sperm. Elife (2015) 0.85
SEB-3, a CRF receptor-like GPCR, regulates locomotor activity states, stress responses and ethanol tolerance in Caenorhabditis elegans. Genes Brain Behav (2012) 0.85
Betaine acts on a ligand-gated ion channel in the nervous system of the nematode C. elegans. Nat Neurosci (2013) 0.84
SACY-1 DEAD-Box helicase links the somatic control of oocyte meiotic maturation to the sperm-to-oocyte switch and gamete maintenance in Caenorhabditis elegans. Genetics (2012) 0.84
Two Rab2 interactors regulate dense-core vesicle maturation. Neuron (2014) 0.84
High-throughput isolation and mapping of C. elegans mutants susceptible to pathogen infection. PLoS One (2008) 0.83
Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans. Genetics (2013) 0.83
The fat-like cadherin CDH-4 acts cell-non-autonomously in anterior-posterior neuroblast migration. Dev Biol (2014) 0.83
When females produce sperm: genetics of C. elegans hermaphrodite reproductive choice. G3 (Bethesda) (2013) 0.83
Sensory transduction channel subunits, tax-4 and tax-2, modify presynaptic molecular architecture in C. elegans. PLoS One (2011) 0.82
Transmembrane protein OSTA-1 shapes sensory cilia morphology via regulation of intracellular membrane trafficking in C. elegans. Development (2013) 0.82
The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage. J Cell Biol (2016) 0.82
The novel intestinal filament organizer IFO-1 contributes to epithelial integrity in concert with ERM-1 and DLG-1. Development (2012) 0.82
Myristoylated CIL-7 regulates ciliary extracellular vesicle biogenesis. Mol Biol Cell (2015) 0.82
GLOBIN-5-dependent O2 responses are regulated by PDL-1/PrBP that targets prenylated soluble guanylate cyclases to dendritic endings. J Neurosci (2014) 0.81
C. elegans ADAMTS ADT-2 regulates body size by modulating TGFβ signaling and cuticle collagen organization. Dev Biol (2011) 0.81
Cell architecture: surrounding muscle cells shape gland cell morphology in the Caenorhabditis elegans pharynx. Genetics (2011) 0.81
APL-1, the Alzheimer's Amyloid precursor protein in Caenorhabditis elegans, modulates multiple metabolic pathways throughout development. Genetics (2012) 0.81
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SDN-1/Syndecan Acts in Parallel to the Transmembrane Molecule MIG-13 to Promote Anterior Neuroblast Migration. G3 (Bethesda) (2015) 0.80
A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover. Hum Mol Genet (2014) 0.79
New role for DCR-1/dicer in Caenorhabditis elegans innate immunity against the highly virulent bacterium Bacillus thuringiensis DB27. Infect Immun (2013) 0.79
From genes to function: the C. elegans genetic toolbox. Wiley Interdiscip Rev Dev Biol (2011) 0.79
Mutations in Caenorhabditis elegans eIF2beta permit translation initiation from non-AUG start codons. Genetics (2010) 0.78
Genetic analysis of a novel tubulin mutation that redirects synaptic vesicle targeting and causes neurite degeneration in C. elegans. PLoS Genet (2014) 0.78
An AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 EGFR basolateral localization and signaling during C. elegans vulva induction. PLoS Genet (2014) 0.78
Regulation of protein quality control by UBE4B and LSD1 through p53-mediated transcription. PLoS Biol (2015) 0.78
The NF-Y complex negatively regulates Caenorhabditis elegans tbx-2 expression. Dev Biol (2013) 0.78
Extension of the Caenorhabditis elegans Pharyngeal M1 neuron axon is regulated by multiple mechanisms. G3 (Bethesda) (2013) 0.78
Multiple phenotypes resulting from a mutagenesis screen for pharynx muscle mutations in Caenorhabditis elegans. PLoS One (2011) 0.78
A Caenorhabditis elegans p38 MAP kinase pathway mutant protects from dopamine, methamphetamine, and MDMA toxicity. Neurosci Lett (2011) 0.78
Nematophagous fungus Arthrobotrys oligospora mimics olfactory cues of sex and food to lure its nematode prey. Elife (2017) 0.77
Regulation of Neuronal Oxygen Responses in C. elegans Is Mediated through Interactions between Globin 5 and the H-NOX Domains of Soluble Guanylate Cyclases. J Neurosci (2016) 0.77
The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis. PLoS Genet (2016) 0.77
Protein phosphatase 5 is a negative regulator of separase function during cortical granule exocytosis in C. elegans. J Cell Sci (2011) 0.77
Promotion of bone morphogenetic protein signaling by tetraspanins and glycosphingolipids. PLoS Genet (2015) 0.77
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Rapid gene mapping in Caenorhabditis elegans using a high density polymorphism map. Nat Genet (2001) 9.54
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A local, high-density, single-nucleotide polymorphism map used to clone Caenorhabditis elegans cdf-1. Genetics (1999) 2.17
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Single-copy insertion of transgenes in Caenorhabditis elegans. Nat Genet (2008) 7.58
Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells. Proc Natl Acad Sci U S A (2006) 6.00
Endophilin is required for synaptic vesicle endocytosis by localizing synaptojanin. Neuron (2003) 5.38
Axon regeneration requires a conserved MAP kinase pathway. Science (2009) 3.48
Improved Mos1-mediated transgenesis in C. elegans. Nat Methods (2012) 3.13
UNC119 is required for G protein trafficking in sensory neurons. Nat Neurosci (2011) 2.38
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Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components. Cell (2010) 2.32
The sensory circuitry for sexual attraction in C. elegans males. Curr Biol (2007) 2.23
Detection of neuron membranes in electron microscopy images using a serial neural network architecture. Med Image Anal (2010) 2.22
Targeted gene deletions in C. elegans using transposon excision. Nat Methods (2010) 2.20
Protons act as a transmitter for muscle contraction in C. elegans. Cell (2008) 2.18
Defects in synaptic vesicle docking in unc-18 mutants. Nat Neurosci (2003) 2.11
C. elegans AP-2 and retromer control Wnt signaling by regulating mig-14/Wntless. Dev Cell (2007) 2.10
UNC-31 (CAPS) is required for dense-core vesicle but not synaptic vesicle exocytosis in Caenorhabditis elegans. J Neurosci (2007) 2.03
EXP-1 is an excitatory GABA-gated cation channel. Nat Neurosci (2003) 1.97
Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans. Genes Dev (2007) 1.94
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Open syntaxin docks synaptic vesicles. PLoS Biol (2007) 1.90
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Long chain polyunsaturated fatty acids are required for efficient neurotransmission in C. elegans. J Cell Sci (2003) 1.38
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V-ATPase V1 sector is required for corpse clearance and neurotransmission in Caenorhabditis elegans. Genetics (2012) 0.82
Visualizing proteins in electron micrographs at nanometer resolution. Methods Cell Biol (2012) 0.82
The plasma membrane calcium ATPase MCA-3 is required for clathrin-mediated endocytosis in scavenger cells of Caenorhabditis elegans. Traffic (2007) 0.82
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Dopamine: should I stay or should I go now? Nat Neurosci (2004) 0.77
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