Published in Am J Physiol Lung Cell Mol Physiol on September 14, 2012
COPD: balancing oxidants and antioxidants. Int J Chron Obstruct Pulmon Dis (2015) 1.03
Molecular mechanisms of acrolein toxicity: relevance to human disease. Toxicol Sci (2015) 0.99
Cigarette smoke and CFTR: implications in the pathogenesis of COPD. Am J Physiol Lung Cell Mol Physiol (2013) 0.96
An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2014) 0.95
The composition of cigarette smoke determines inflammatory cell recruitment to the lung in COPD mouse models. Clin Sci (Lond) (2014) 0.93
Effects of cigarette smoke on Toll-like receptor (TLR) activation of chronic obstructive pulmonary disease (COPD) macrophages. Clin Exp Immunol (2014) 0.93
Cigarette smoke enhances human rhinovirus-induced CXCL8 production via HuR-mediated mRNA stabilization in human airway epithelial cells. Respir Res (2013) 0.83
Short-term airborne particulate matter exposure alters the epigenetic landscape of human genes associated with the mitogen-activated protein kinase network: a cross-sectional study. Environ Health (2014) 0.83
Electronic cigarette exposure triggers neutrophil inflammatory responses. Respir Res (2016) 0.79
Impacts of cigarette smoking on immune responsiveness: Up and down or upside down? Oncotarget (2016) 0.79
Oral and inhaled p38 MAPK inhibitors: effects on inhaled LPS challenge in healthy subjects. Eur J Clin Pharmacol (2015) 0.78
A Potential Role for Acrolein in Neutrophil-Mediated Chronic Inflammation. Inflammation (2015) 0.76
Epithelial Anion Transport as Modulator of Chemokine Signaling. Mediators Inflamm (2016) 0.75
Acute systemic accumulation of acrolein in mice by inhalation at a concentration similar to that in cigarette smoke. Neurosci Bull (2014) 0.75
Curcumin modulates the effect of histone modification on the expression of chemokines by type II alveolar epithelial cells in a rat COPD model. Int J Chron Obstruct Pulmon Dis (2016) 0.75
Mitochondrial alterations during oxidative stress in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis (2017) 0.75
Adverse Outcomes Associated with Cigarette Smoke Radicals Related to Damage to Protein-disulfide Isomerase. J Biol Chem (2016) 0.75
Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD. PLoS One (2016) 0.75
Isorhapontigenin, a bioavailable dietary polyphenol, suppresses airway epithelial cell inflammation through a corticosteroid-independent mechanism. Br J Pharmacol (2017) 0.75
Effects of Cigarette Smoking on Transplant Survival: Extending or Shortening It? Front Immunol (2017) 0.75
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci U S A (2007) 4.10
The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines. Proc Natl Acad Sci U S A (2011) 2.38
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents. J Clin Invest (2008) 2.20
Predictors of objective cough frequency in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2013) 1.64
Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1. Proc Natl Acad Sci U S A (2008) 1.59
Once-daily NVA237 improves exercise tolerance from the first dose in patients with COPD: the GLOW3 trial. Int J Chron Obstruct Pulmon Dis (2012) 1.52
Efficacy and safety of tiotropium Respimat SMI in COPD in two 1-year randomized studies. Int J Chron Obstruct Pulmon Dis (2010) 1.51
Increased airway T regulatory cells in asthmatic subjects. Chest (2010) 1.50
Efficacy and safety of twice-daily aclidinium bromide in COPD patients: the ATTAIN study. Eur Respir J (2012) 1.50
A comparison of lung function methods for assessing dose-response effects of salbutamol. Br J Clin Pharmacol (2004) 1.45
Alpha,beta-unsaturated aldehydes in cigarette smoke release inflammatory mediators from human macrophages. Am J Respir Cell Mol Biol (2007) 1.40
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation. Pain (2011) 1.35
Hydrogen sulfide causes vanilloid receptor 1-mediated neurogenic inflammation in the airways. Br J Pharmacol (2005) 1.34
1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity. J Pharmacol Exp Ther (2007) 1.29
MUC5B is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2008) 1.27
CD4-regulatory cells in COPD patients. Chest (2007) 1.27
alpha,beta-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases. Am J Physiol Lung Cell Mol Physiol (2009) 1.24
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation. PLoS One (2012) 1.23
Impulse oscillometry in COPD: identification of measurements related to airway obstruction, airway conductance and lung volumes. Respir Med (2008) 1.19
Safety of indacaterol in the treatment of patients with COPD. Int J Chron Obstruct Pulmon Dis (2011) 1.19
In skeletal muscle advanced glycation end products (AGEs) inhibit insulin action and induce the formation of multimolecular complexes including the receptor for AGEs. J Biol Chem (2008) 1.11
The effect of inhaled IFN-β on worsening of asthma symptoms caused by viral infections. A randomized trial. Am J Respir Crit Care Med (2014) 1.11
Neurogenic potential of human mesenchymal stem cells revisited: analysis by immunostaining, time-lapse video and microarray. J Cell Sci (2005) 1.11
Genetics of sputum gene expression in chronic obstructive pulmonary disease. PLoS One (2011) 1.11
Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion. J Med Chem (2005) 1.07
Phorbol ester-stimulated NF-kappaB-dependent transcription: roles for isoforms of novel protein kinase C. Cell Signal (2008) 1.07
The use of plethysmography and oscillometry to compare long-acting bronchodilators in patients with COPD. Br J Clin Pharmacol (2008) 1.06
Depression and its relationship with poor exercise capacity, BODE index and muscle wasting in COPD. Respir Med (2009) 1.06
Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor. J Endocrinol (2008) 1.05
Impact factor and its role in academic promotion. Int J Chron Obstruct Pulmon Dis (2009) 1.04
The effect of peroxisome proliferator-activated receptor-γ ligands on in vitro and in vivo models of COPD. Eur Respir J (2013) 1.04
A nick-sensing DNA 3'-repair enzyme from Arabidopsis. J Biol Chem (2002) 1.03
Increased phosphorylated p38 mitogen-activated protein kinase in COPD lungs. Eur Respir J (2012) 1.02
TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism. Pflugers Arch (2012) 1.01
Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast. Genome Biol (2008) 1.00
Regulation of tristetraprolin expression by interleukin-1 beta and dexamethasone in human pulmonary epithelial cells: roles for nuclear factor-kappa B and p38 mitogen-activated protein kinase. J Pharmacol Exp Ther (2009) 0.99
Novel therapeutic strategy to prevent chemotherapy-induced persistent sensory neuropathy by TRPA1 blockade. Cancer Res (2013) 0.99
The repeatability of interleukin-6, tumor necrosis factor-alpha, and C-reactive protein in COPD patients over one year. Int J Chron Obstruct Pulmon Dis (2009) 0.98
T lymphocyte insensitivity to corticosteroids in chronic obstructive pulmonary disease. Respir Res (2012) 0.97
COPD phenotype description using principal components analysis. Respir Res (2009) 0.97
Non-invasive phenotyping using exhaled volatile organic compounds in asthma. Thorax (2011) 0.97
Cough: The Emerging Role of the TRPA1 Channel. Lung (2009) 0.96
Cigarette smoke extract induced cytokine and chemokine gene expression changes in COPD macrophages. Cytokine (2008) 0.95
Biomarkers of systemic inflammation and depression and fatigue in moderate clinically stable COPD. Respir Res (2011) 0.95
Identification of lipocalin and apolipoprotein A1 as biomarkers of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 0.94
Non-invasive metabolomic analysis of breath using differential mobility spectrometry in patients with chronic obstructive pulmonary disease and healthy smokers. Analyst (2010) 0.93
Neutrophil chemotaxis caused by chronic obstructive pulmonary disease alveolar macrophages: the role of CXCL8 and the receptors CXCR1/CXCR2. J Pharmacol Exp Ther (2013) 0.93
A comparison of exhaled nitric oxide measurements performed using three different analysers. Respir Med (2006) 0.92
LPS challenge in healthy subjects: an investigation of neutrophil chemotaxis mechanisms involving CXCR1 and CXCR2. Int Immunopharmacol (2012) 0.91
Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol (2002) 0.91
In vivo imaging of transiently transgenized mice with a bovine interleukin 8 (CXCL8) promoter/luciferase reporter construct. PLoS One (2012) 0.90
Hydrogen sulfide inhibits human platelet aggregation. Eur J Pharmacol (2007) 0.90
ENPP1 affects insulin action and secretion: evidences from in vitro studies. PLoS One (2011) 0.90
Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel. Pain (2013) 0.89
A new, potent urotensin II receptor peptide agonist containing a Pen residue at the disulfide bridge. J Med Chem (2002) 0.89
Cigarette smoke and α,β-unsaturated aldehydes elicit VEGF release through the p38 MAPK pathway in human airway smooth muscle cells and lung fibroblasts. Br J Pharmacol (2011) 0.89
Loss of glucocorticoid receptor expression by DNA methylation prevents glucocorticoid induced apoptosis in human small cell lung cancer cells. PLoS One (2011) 0.89
Inhaled LPS challenges in smokers: a study of pulmonary and systemic effects. Br J Clin Pharmacol (2012) 0.88
TRP channels as therapeutic targets in airway disorders: a patent review. Expert Opin Ther Pat (2012) 0.88
The effects of dexamethasone on cigarette smoke induced gene expression changes in COPD macrophages. Int Immunopharmacol (2009) 0.87
Reduced glucocorticoid receptor expression and function in airway neutrophils. Int Immunopharmacol (2011) 0.87
Effects of capsaicin on visceral smooth muscle: a valuable tool for sensory neurotransmitter identification. Eur J Pharmacol (2004) 0.87
In vitro and in vivo profiling of CHF5022 and CHF5074 Two beta-amyloid1-42 lowering agents. Pharmacol Res (2007) 0.87
MR Quantitative Equilibrium Signal Mapping: A Reliable Alternative to CT in the Assessment of Emphysema in Patients with Chronic Obstructive Pulmonary Disease. Radiology (2015) 0.86
Evaluation of glucocorticoid receptor function in COPD lung macrophages using beclomethasone-17-monopropionate. PLoS One (2013) 0.86
Acrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary disease. Ann N Y Acad Sci (2012) 0.86
Induction of regulator of G-protein signaling 2 expression by long-acting β2-adrenoceptor agonists and glucocorticoids in human airway epithelial cells. J Pharmacol Exp Ther (2013) 0.85
Cannabidiol, unlike synthetic cannabinoids, triggers activation of RBL-2H3 mast cells. J Leukoc Biol (2007) 0.85
Down regulation of T cell receptor expression in COPD pulmonary CD8 cells. PLoS One (2013) 0.84
Non-invasive biomarkers and pulmonary function in smokers. Int J Chron Obstruct Pulmon Dis (2008) 0.84
The role of the liver X receptor in chronic obstructive pulmonary disease. Respir Res (2013) 0.83
Novel anti-inflammatory agents in COPD: targeting lung and systemic inflammation. Curr Drug Targets (2013) 0.83
Increased levels of soluble interleukin-6 receptor and CCL3 in COPD sputum. Respir Res (2014) 0.83
Urotensin-II receptor ligands. From agonist to antagonist activity. J Med Chem (2005) 0.83
Characterization of the inflammatory response to inhaled lipopolysaccharide in mild to moderate chronic obstructive pulmonary disease. Br J Clin Pharmacol (2015) 0.82
The EvA study: aims and strategy. Eur Respir J (2012) 0.81
Comparison of the effects of salmeterol/fluticasone propionate with fluticasone propionate on airway physiology in adults with mild persistent asthma. Respir Res (2007) 0.81
CRAC channel inhibition produces greater anti-inflammatory effects than glucocorticoids in CD8 cells from COPD patients. Clin Sci (Lond) (2014) 0.81
Exhaled volatile organic compounds for phenotyping chronic obstructive pulmonary disease: a cross-sectional study. Respir Res (2012) 0.81
Reduced exhaled breath condensate pH in asthmatic smokers using inhaled corticosteroids. Respirology (2009) 0.80
Corticosteroid insensitive alveolar macrophages from asthma patients; synergistic interaction with a p38 mitogen-activated protein kinase (MAPK) inhibitor. Br J Clin Pharmacol (2015) 0.80
The effect of asthma therapeutics on signalling and transcriptional regulation of airway smooth muscle function. Pulm Pharmacol Ther (2008) 0.80
Receptor for advanced glycation end products contributes to postnatal pulmonary development and adult lung maintenance program in mice. Am J Respir Cell Mol Biol (2012) 0.79
Pharmacological assessment of the duration of action of glycopyrrolate vs tiotropium and ipratropium in guinea-pig and human airways. Br J Pharmacol (2006) 0.79
Camphor, an old cough remedy with a new mechanism. Am J Respir Crit Care Med (2012) 0.78
Diesel exhaust particle exposure in vitro alters monocyte differentiation and function. PLoS One (2012) 0.78
P38 inhibition in COPD; cautious optimism. Thorax (2013) 0.78
A comparison of the clinical and induced sputum characteristics of early- and late-onset asthma. Lung (2012) 0.78
Genome-wide inventory of metal homeostasis-related gene products including a functional phytochelatin synthase in the hypogeous mycorrhizal fungus Tuber melanosporum. Fungal Genet Biol (2010) 0.78