Published in J Biochem on September 14, 2012
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Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production. Mol Cell Biol (2013) 1.00
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Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy. Brain (2013) 0.89
Genetic loci associated with circulating levels of very long-chain saturated fatty acids. J Lipid Res (2014) 0.89
Acylation in trypanosomatids: an essential process and potential drug target. Trends Parasitol (2014) 0.88
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Fatty acylation of Wnt proteins. Nat Chem Biol (2016) 0.87
Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid. J Lipid Res (2014) 0.85
Essential role of the cytochrome P450 CYP4F22 in the production of acylceramide, the key lipid for skin permeability barrier formation. Proc Natl Acad Sci U S A (2015) 0.84
Cooperative Synthesis of Ultra Long-Chain Fatty Acid and Ceramide during Keratinocyte Differentiation. PLoS One (2013) 0.84
Effects on vesicular transport pathways at the late endosome in cells with limited very long-chain fatty acids. J Lipid Res (2013) 0.83
Mutation for nonsyndromic mental retardation in the trans-2-enoyl-CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability, leading to change in sphingolipid profile. J Biol Chem (2013) 0.83
Fatty acid metabolism and the basis of brown adipose tissue function. Adipocyte (2015) 0.82
In situ characterizing membrane lipid phenotype of breast cancer cells using mass spectrometry profiling. Sci Rep (2015) 0.81
Epidermal barriers. Cold Spring Harb Perspect Med (2014) 0.81
Dual functions of the trans-2-enoyl-CoA reductase TER in the sphingosine 1-phosphate metabolic pathway and in fatty acid elongation. J Biol Chem (2014) 0.80
Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis. Biochim Biophys Acta (2015) 0.79
Fatty acid chain elongation in palmitate-perfused working rat heart: mitochondrial acetyl-CoA is the source of two-carbon units for chain elongation. J Biol Chem (2014) 0.79
Circulating Very-Long-Chain Saturated Fatty Acids and Incident Coronary Heart Disease in US Men and Women. Circulation (2015) 0.78
Phs1 and the synthesis of very long chain Fatty acids are required for ballistospore formation. PLoS One (2014) 0.78
Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Downregulates ELOVL1 Gene Expression and Fatty Acid Synthesis in Goat Fetal Fibroblasts. Int J Mol Sci (2015) 0.77
Application of quantitative trait locus mapping and transcriptomics to studies of the senescence-accelerated phenotype in rats. BMC Genomics (2014) 0.77
A palmitic acid elongase affects eicosapentaenoic acid and plastidal monogalactosyldiacylglcerol levels in Nannochloropsis. Plant Physiol (2016) 0.77
A more desirable balanced polyunsaturated fatty acid composition achieved by heterologous expression of Δ15/Δ4 desaturases in mammalian cells. PLoS One (2013) 0.76
Long-chain polyunsaturated fatty acids attenuate the IL-1β-induced proinflammatory response in human fetal intestinal epithelial cells. Pediatr Res (2015) 0.76
PNPLA1 is a transacylase essential for the generation of the skin barrier lipid ω-O-acylceramide. Nat Commun (2017) 0.76
HACD1, a regulator of membrane composition and fluidity, promotes myoblast fusion and skeletal muscle growth. J Mol Cell Biol (2015) 0.76
Role of docosahexaenoic acid in the modulation of glial cells in Alzheimer's disease. J Neuroinflammation (2016) 0.76
Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region. J Biol Chem (2016) 0.76
Rom2-dependent phosphorylation of Elo2 controls the abundance of very long-chain fatty acids. J Biol Chem (2014) 0.76
Isolation and characterization of the diatom Phaeodactylum Δ5-elongase gene for transgenic LC-PUFA production in Pichia pastoris. Mar Drugs (2014) 0.75
Clinical and neuroradiological features of spinocerebellar ataxia 38 (SCA38). Parkinsonism Relat Disord (2016) 0.75
Rapamycin Inhibits Expression of Elongation of Very-long-chain Fatty Acids 1 and Synthesis of Docosahexaenoic Acid in Bovine Mammary Epithelial Cells. Asian-Australas J Anim Sci (2016) 0.75
Harnessing the power of yeast to elucidate the role of sphingolipids in metabolic and signaling processes pertinent to psychiatric disorders. Clin Lipidol (2014) 0.75
Effect of high carbohydrate diet on elongase and desaturase activity and accompanying gene expression in rat's liver. Genes Nutr (2017) 0.75
Dietary Very Long Chain Saturated Fatty Acids and Metabolic Factors: Findings from the Korea National Health and Nutrition Examination Survey 2013. Clin Nutr Res (2015) 0.75
Two modes of regulation of the fatty acid elongase ELOVL6 by the 3-ketoacyl-CoA reductase KAR in the fatty acid elongation cycle. PLoS One (2014) 0.75
Early Trypanosoma cruzi infection reprograms human epithelial cells. Biomed Res Int (2014) 0.75
Phytosphingosine degradation pathway includes fatty acid α-oxidation reactions in the endoplasmic reticulum. Proc Natl Acad Sci U S A (2017) 0.75
Brain Lipotoxicity of Phytanic Acid and Very Long-chain Fatty Acids. Harmful Cellular/Mitochondrial Activities in Refsum Disease and X-Linked Adrenoleukodystrophy. Aging Dis (2016) 0.75
Comparative Serum Fatty Acid Profiles of Captive and Free-Ranging Cheetahs (Acinonyx jubatus) in Namibia. PLoS One (2016) 0.75
Actions and Mechanisms of Polyunsaturated Fatty Acids on Voltage-Gated Ion Channels. Front Physiol (2017) 0.75
Can dietary saturated fat be beneficial in prevention of stroke risk? A meta-analysis. Neurol Sci (2016) 0.75
Targeted metabolomic profiling indicates structure-based perturbations in serum phospholipids in children with acetaminophen overdose. Toxicol Rep (2016) 0.75
The 3-hydroxyacyl-CoA dehydratases HACD1 and HACD2 exhibit functional redundancy and are active in a wide range of fatty acid elongation pathways. J Biol Chem (2017) 0.75