Published in Blood on September 18, 2012
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New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases. World J Gastroenterol (2014) 0.96
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Testing the iron hypothesis in a mouse model of atherosclerosis. Cell Rep (2013) 0.85
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Hepcidin level predicts hemoglobin concentration in individuals undergoing repeated phlebotomy. Haematologica (2013) 0.81
A chemical screen identifies small molecules that regulate hepcidin expression. Blood Cells Mol Dis (2014) 0.80
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Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia. JCI Insight (2017) 0.78
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Hepcidin inhibits Smad3 phosphorylation in hepatic stellate cells by impeding ferroportin-mediated regulation of Akt. Nat Commun (2016) 0.75
Mössbauer Spectra of Mouse Hearts Reveal Age-dependent Changes in Mitochondrial and Ferritin Iron Levels. J Biol Chem (2017) 0.75
Dietary supplementation with ipriflavone decreases hepatic iron stores in wild type mice. Blood Cells Mol Dis (2016) 0.75
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Targeting iron metabolism in drug discovery and delivery. Nat Rev Drug Discov (2017) 0.75
In a Mouse Model of Sepsis, Hepcidin Ablation Ameliorates Anemia More Effectively Than Iron and Erythropoietin Treatment. Shock (2017) 0.75
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Iron overload in non-transfusion-dependent thalassemia: a clinical perspective. Blood Rev (2012) 1.48
Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice. Blood (2005) 1.18
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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science (2004) 19.19
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Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Engl J Med (2002) 9.01
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Immunoassay for human serum hepcidin. Blood (2008) 5.32
High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nat Med (2007) 5.18
Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci U S A (2005) 5.05
Lack of the bone morphogenetic protein BMP6 induces massive iron overload. Nat Genet (2009) 4.49
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Hepcidin is decreased in TFR2 hemochromatosis. Blood (2004) 3.46
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Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. Blood (2007) 2.51
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Retracted The hepcidin-binding site on ferroportin is evolutionarily conserved. Cell Metab (2008) 2.25
Urinary hepcidin excretion in patients with myelodysplastic syndrome and myelofibrosis. Br J Haematol (2008) 2.25
Proinflammatory state, hepcidin, and anemia in older persons. Blood (2010) 2.19
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The molecular basis of ferroportin-linked hemochromatosis. Proc Natl Acad Sci U S A (2005) 2.10
Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs. Blood (2005) 2.08
In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2. Blood (2010) 2.03
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The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis. J Biol Chem (2002) 1.89
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Blunted hepcidin response to oral iron challenge in HFE-related hemochromatosis. Blood (2007) 1.78
Posttranslational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furin. Blood Cells Mol Dis (2007) 1.76
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Severe hemochromatosis in a Portuguese family associated with a new mutation in the 5'-UTR of the HAMP gene. Blood (2004) 1.64
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The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study. Blood (2005) 1.60
Urinary hepcidin in congenital chronic anemias. Pediatr Blood Cancer (2007) 1.58
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Increased genomic copy number of DEFA1/DEFA3 is associated with susceptibility to severe sepsis in Chinese Han population. Anesthesiology (2010) 1.58
Involvement of hepcidin in the anemia of multiple myeloma. Clin Cancer Res (2008) 1.57
Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens. J Immunol (2006) 1.55
By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide. J Immunol (2003) 1.54
The molecular basis of hepcidin-resistant hereditary hemochromatosis. Blood (2009) 1.51
Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization. Haematologica (2009) 1.51
Testosterone suppresses hepcidin in men: a potential mechanism for testosterone-induced erythrocytosis. J Clin Endocrinol Metab (2010) 1.50
Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload. J Clin Invest (2011) 1.49
Hepcidin and iron-loading anemias. Haematologica (2006) 1.49
Reduced serum hepcidin levels in patients with chronic hepatitis C. J Hepatol (2009) 1.48
Novel urine hepcidin assay by mass spectrometry. Blood (2005) 1.46
Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood (2004) 1.44
Impaired intestinal iron absorption in Crohn's disease correlates with disease activity and markers of inflammation. Inflamm Bowel Dis (2006) 1.43