Obesity and prostate cancer: gene expression signature of human periprostatic adipose tissue.

PubWeight™: 1.13‹?› | Rank: Top 10%

🔗 View Article (PMC 3523039)

Published in BMC Med on September 25, 2012

Authors

Ricardo Ribeiro1, Cátia Monteiro, Victoria Catalán, Pingzhao Hu, Virgínia Cunha, Amaia Rodríguez, Javier Gómez-Ambrosi, Avelino Fraga, Paulo Príncipe, Carlos Lobato, Francisco Lobo, António Morais, Vitor Silva, José Sanches-Magalhães, Jorge Oliveira, Francisco Pina, Carlos Lopes, Rui Medeiros, Gema Frühbeck

Author Affiliations

1: Molecular Oncology Group, Portuguese Institute of Oncology, Ed, Laboratórios-Piso 4, Rua Dr, António Bernardino de Almeida 4200-072, Porto, Portugal. oriebir.r@gmail.com

Articles citing this

Obesity and prostate cancer: weighing the evidence. Eur Urol (2012) 2.01

Structure of the large ribosomal subunit from human mitochondria. Science (2014) 1.64

Adipose tissue immunity and cancer. Front Physiol (2013) 0.96

Bariatric and metabolic surgery: a shift in eligibility and success criteria. Nat Rev Endocrinol (2015) 0.89

Mechanisms linking excess adiposity and carcinogenesis promotion. Front Endocrinol (Lausanne) (2014) 0.86

Five common haplotype-tagging variants of adiponectin (ADIPOQ) and cancer susceptibility: a meta-analysis. Genet Test Mol Biomarkers (2014) 0.82

Inorganic Arsenic-Related Changes in the Stromal Tumor Microenvironment in a Prostate Cancer Cell-Conditioned Media Model. Environ Health Perspect (2015) 0.82

The relationship between obesity and prostate cancer: from genetics to disease treatment and prevention. BMC Med (2012) 0.79

Obesity: The fat advantage. Nature (2016) 0.77

Ceruloplasmin is a novel adipokine which is overexpressed in adipose tissue of obese subjects and in obesity-associated cancer cells. PLoS One (2014) 0.77

Diet, obesity, and cancer progression: are adipocytes the link? Lipid Insights (2013) 0.77

Linking obesogenic dysregulation to prostate cancer progression. Endocr Connect (2015) 0.77

White adipose tissue inflammation and cancer-specific survival in patients with squamous cell carcinoma of the oral tongue. Cancer (2016) 0.77

Genome-wide association study for feed efficiency and growth traits in U.S. beef cattle. BMC Genomics (2017) 0.75

IL-32α-induced inflammation constitutes a link between obesity and colon cancer. Oncoimmunology (2017) 0.75

Obesity and metabolic dysfunction severely influence prostate cell function: role of insulin and IGF1. J Cell Mol Med (2017) 0.75

Periprostatic adipose inflammation is associated with high-grade prostate cancer. Prostate Cancer Prostatic Dis (2017) 0.75

Articles cited by this

Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol (2004) 101.91

Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res (2003) 52.74

Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med (2003) 35.39

Tumor metastasis: molecular insights and evolving paradigms. Cell (2011) 10.34

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell (2006) 9.47

Cancer incidence and mortality in Europe, 2004. Ann Oncol (2005) 6.47

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat Med (2011) 6.15

Biological action of leptin as an angiogenic factor. Science (1998) 6.02

Obesity and cancer: the role of dysfunctional adipose tissue. Cancer Epidemiol Biomarkers Prev (2009) 3.25

Periprostatic adipose tissue as a modulator of prostate cancer aggressiveness. J Urol (2009) 2.54

Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. Biochem Biophys Res Commun (2003) 2.52

Adiponutrin, a transmembrane protein corresponding to a novel dietary- and obesity-linked mRNA specifically expressed in the adipose lineage. J Biol Chem (2001) 2.33

CD20: a regulator of cell-cycle progression of B lymphocytes. Immunol Today (1994) 2.25

Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Cancer Res (2010) 2.02

The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. Proc Natl Acad Sci U S A (2009) 1.98

Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity. J Lipid Res (2006) 1.88

MicroRNA let-7 regulates 3T3-L1 adipogenesis. Mol Endocrinol (2009) 1.71

The link between obesity and prostate cancer: the leptin pathway and therapeutic perspectives. Prostate Cancer Prostatic Dis (2006) 1.60

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice. J Clin Invest (2010) 1.57

Obese men have higher-grade and larger tumors: an analysis of the duke prostate center database. Prostate Cancer Prostatic Dis (2009) 1.54

The growing challenge of obesity and cancer: an inflammatory issue. Ann N Y Acad Sci (2011) 1.47

Gene expression profile of omental adipose tissue in human obesity. FASEB J (2003) 1.42

Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function. J Cell Sci (2009) 1.39

Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk. Exp Biol Med (Maywood) (2010) 1.37

Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex. J Biol Chem (2007) 1.37

Fibroblast growth factor-16 is a growth factor for embryonic brown adipocytes. J Biol Chem (2000) 1.32

Validation of endogenous control genes in human adipose tissue: relevance to obesity and obesity-associated type 2 diabetes mellitus. Horm Metab Res (2007) 1.31

Human periprostatic adipose tissue promotes prostate cancer aggressiveness in vitro. J Exp Clin Cancer Res (2012) 1.28

A fundamental bimodal role for neuropeptide Y1 receptor in the immune system. J Exp Med (2005) 1.25

Neuropeptide Y is produced in visceral adipose tissue and promotes proliferation of adipocyte precursor cells via the Y1 receptor. FASEB J (2008) 1.14

Associating quantitative behavioral traits with gene expression in the brain: searching for diamonds in the hay. Bioinformatics (2007) 1.13

Comprehensive human adipose tissue mRNA and microRNA endogenous control selection for quantitative real-time-PCR normalization. Obesity (Silver Spring) (2010) 1.11

Leptin and cancer: from cancer stem cells to metastasis. Endocr Relat Cancer (2011) 1.11

Correlation of margin status and extraprostatic extension with progression of prostate carcinoma. Cancer (1999) 1.09

Developmental and metabolic effects of disruption of the mouse CTP:phosphoethanolamine cytidylyltransferase gene (Pcyt2). Mol Cell Biol (2007) 1.05

Adipose tissue growth and regression are regulated by angiopoietin-1. Biochem Biophys Res Commun (2003) 1.05

In vitro lipolytic effect of leptin on mouse adipocytes: evidence for a possible autocrine/paracrine role of leptin. Biochem Biophys Res Commun (1997) 1.04

Apoptosis induction by eIF5A1 involves activation of the intrinsic mitochondrial pathway. J Cell Physiol (2010) 1.02

Regulation of alternative pathway activation and C3a production by adipose cells. Obes Res (1996) 1.01

Clinical significance of the leptin and leptin receptor expressions in prostate tissues. Asian J Androl (2008) 1.01

Integration of protein kinases mTOR and extracellular signal-regulated kinase 5 in regulating nucleocytoplasmic localization of NFATc4. Mol Cell Biol (2008) 1.00

Periprostatic fat correlates with tumour aggressiveness in prostate cancer patients. BJU Int (2010) 1.00

Obesity-related systemic factors promote an invasive phenotype in prostate cancer cells. Prostate Cancer Prostatic Dis (2012) 0.99

Identification of XAF1 as a novel cell cycle regulator through modulating G(2)/M checkpoint and interaction with checkpoint kinase 1 in gastrointestinal cancer. Carcinogenesis (2009) 0.96

Increased levels of calprotectin in obesity are related to macrophage content: impact on inflammation and effect of weight loss. Mol Med (2011) 0.94

Angiopoietin-1 promotes endothelial differentiation from embryonic stem cells and induced pluripotent stem cells. Blood (2011) 0.93

The expression of angiopoietins and their receptor Tie-2 in human prostate carcinoma. Anticancer Res (2001) 0.91

The possible role of factor H in colon cancer resistance to complement attack. Int J Cancer (2008) 0.90

Control of body weight: a physiologic and transgenic perspective. Diabetologia (2003) 0.89

Nuclear PLCbeta1 is required for 3T3-L1 adipocyte differentiation and regulates expression of the cyclin D3-cdk4 complex. Cell Signal (2009) 0.88

Signaling by the cysteinyl-leukotriene receptor 2. Involvement in chemokine gene transcription. J Biol Chem (2007) 0.88

Depletion of tubulin polymerization promoting protein family member 3 suppresses HeLa cell proliferation. Mol Cell Biochem (2009) 0.87

Gadd45b mediates Fas-induced apoptosis by enhancing the interaction between p38 and retinoblastoma tumor suppressor. J Biol Chem (2010) 0.87

Enhancement of adipogenesis induction by conditioned media obtained from cancer cells. Cancer Lett (2008) 0.83

Immunoinflammatory mechanisms in lung cancer development: is leptin a mediator? J Thorac Oncol (2007) 0.82

Tumor cell-educated periprostatic adipose tissue acquires an aggressive cancer-promoting secretory profile. Cell Physiol Biochem (2012) 0.81

Structure, function, property, and role in neurologic diseases and other diseases of the sHsp22. J Neurosci Res (2007) 0.81

Characterization of NPY receptors controlling lipolysis and leptin secretion in human adipocytes. FEBS Lett (2000) 0.81

Angiopoietin-1 alters tumor growth by stabilizing blood vessels or by promoting angiogenesis. Cancer Sci (2008) 0.80

Exposure to phosphodiesterase type 5 inhibitors stimulates aromatase expression in human adipocytes in vitro. J Sex Med (2010) 0.80

Articles by these authors

Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling. Cell (2006) 5.72

A census of human soluble protein complexes. Cell (2012) 3.90

Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes. Diabetes (2006) 2.85

Phase III study comparing cisplatin plus fluorouracil to paclitaxel, cisplatin, and fluorouracil induction chemotherapy followed by chemoradiotherapy in locally advanced head and neck cancer. J Clin Oncol (2005) 2.66

Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis. Lancet Oncol (2012) 2.34

Chlamydia trachomatis infection: implications for HPV status and cervical cancer. Arch Gynecol Obstet (2013) 2.28

SNVer: a statistical tool for variant calling in analysis of pooled or individual next-generation sequencing data. Nucleic Acids Res (2011) 2.27

NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2. Gut (2011) 2.26

A quantitative promoter methylation profile of prostate cancer. Clin Cancer Res (2004) 2.06

Targeting the circulating microRNA signature of obesity. Clin Chem (2013) 1.95

Inflammation is associated with a decrease of lipogenic factors in omental fat in women. Am J Physiol Regul Integr Comp Physiol (2008) 1.88

The relationship of serum osteocalcin concentration to insulin secretion, sensitivity, and disposal with hypocaloric diet and resistance training. J Clin Endocrinol Metab (2008) 1.85

The TREAT-NMD Duchenne muscular dystrophy registries: conception, design, and utilization by industry and academia. Hum Mutat (2013) 1.78

Quantitative RARbeta2 hypermethylation: a promising prostate cancer marker. Clin Cancer Res (2004) 1.76

Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer. J Mol Med (Berl) (2006) 1.72

The decrease in plasma ghrelin concentrations following bariatric surgery depends on the functional integrity of the fundus. Obes Surg (2004) 1.65

Differential gene profiling in acute lung injury identifies injury-specific gene expression. Crit Care Med (2008) 1.65

Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples. Clin Cancer Res (2010) 1.62

COX-2 polymorphisms and colorectal cancer risk: a strategy for chemoprevention. Eur J Gastroenterol Hepatol (2010) 1.59

Salutary effect of resveratrol on sepsis-induced myocardial depression. Crit Care Med (2012) 1.55

Circulating betatrophin concentrations are decreased in human obesity and type 2 diabetes. J Clin Endocrinol Metab (2014) 1.51

External validation of a classification for methylene blue magnification chromoendoscopy in premalignant gastric lesions. Gastrointest Endosc (2008) 1.51

Short-term effects of sleeve gastrectomy and caloric restriction on blood pressure in diet-induced obese rats. Obes Surg (2012) 1.51

Plasma osteopontin levels and expression in adipose tissue are increased in obesity. J Clin Endocrinol Metab (2007) 1.51

Intermediate-term results, up to 4 years, of a bone-anchored male perineal sling for treating male stress urinary incontinence after prostate surgery. BJU Int (2008) 1.50

Gene and miRNA expression profiles in autism spectrum disorders. Brain Res (2010) 1.42

Gene expression profile of omental adipose tissue in human obesity. FASEB J (2003) 1.42

A role for microRNA-155 expression in microenvironment associated to HPV-induced carcinogenesis in K14-HPV16 transgenic mice. PLoS One (2015) 1.41

Magnification chromoendoscopy for the diagnosis of gastric intestinal metaplasia and dysplasia. Gastrointest Endosc (2003) 1.39

Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer. BMC Cancer (2011) 1.39

Neuregulin 1-alpha regulates phosphorylation, acetylation, and alternative splicing in lymphoblastoid cells. Genome (2013) 1.38

Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob mice. PLoS One (2009) 1.36

Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice. J Clin Invest (2010) 1.35

Data integration in genetics and genomics: methods and challenges. Hum Genomics Proteomics (2009) 1.32

High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients. Clin Cancer Res (2007) 1.30

Human periprostatic adipose tissue promotes prostate cancer aggressiveness in vitro. J Exp Clin Cancer Res (2012) 1.28

A European case series of endoscopic submucosal dissection for gastric superficial lesions. Gastrointest Endosc (2009) 1.27

Diabetic nephropathy amelioration by a low-dose sitagliptin in an animal model of type 2 diabetes (Zucker diabetic fatty rat). Exp Diabetes Res (2011) 1.23

Body adiposity and type 2 diabetes: increased risk with a high body fat percentage even having a normal BMI. Obesity (Silver Spring) (2011) 1.22

Fruit and vegetable consumption and gastric cancer by location and histological type: case-control and meta-analysis. Eur J Cancer Prev (2007) 1.21

Overexpressing leptin genetic polymorphism (-2548 G/A) is associated with susceptibility to prostate cancer and risk of advanced disease. Prostate (2004) 1.20

TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers. Epigenetics (2011) 1.20

Complement factor H is expressed in adipose tissue in association with insulin resistance. Diabetes (2009) 1.19

MT1G hypermethylation is associated with higher tumor stage in prostate cancer. Cancer Epidemiol Biomarkers Prev (2005) 1.18

Executive functions profile in extreme eating/weight conditions: from anorexia nervosa to obesity. PLoS One (2012) 1.18

E-Cadherin (CDH1) and p53 rather than SMAD4 and Caspase-10 germline mutations contribute to genetic predisposition in Portuguese gastric cancer patients. Eur J Cancer (2004) 1.17

Prenatal exposure to maternal cigarette smoking and DNA methylation: epigenome-wide association in a discovery sample of adolescents and replication in an independent cohort at birth through 17 years of age. Environ Health Perspect (2014) 1.17

The inhibitory effect of leptin on angiotensin II-induced vasoconstriction in vascular smooth muscle cells is mediated via a nitric oxide-dependent mechanism. Endocrinology (2006) 1.16

Proinflammatory cytokines in obesity: impact of type 2 diabetes mellitus and gastric bypass. Obes Surg (2007) 1.15

Expression of caveolin-1 in human adipose tissue is upregulated in obesity and obesity-associated type 2 diabetes mellitus and related to inflammation. Clin Endocrinol (Oxf) (2007) 1.15

Genetic polymorphisms of the epidermal growth factor and related receptor in non-small cell lung cancer--a review of the literature. Oncologist (2007) 1.15

Circulating pigment epithelium-derived factor levels are associated with insulin resistance and decrease after weight loss. J Clin Endocrinol Metab (2010) 1.14

Circulating omentin concentration increases after weight loss. Nutr Metab (Lond) (2010) 1.13

The gene expression of the main lipogenic enzymes is downregulated in visceral adipose tissue of obese subjects. Obesity (Silver Spring) (2009) 1.12

Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer. Urology (2002) 1.11

Visceral fat accumulation as a risk factor for prostate cancer. Obes Res (2004) 1.11