Published in FEBS J on October 22, 2012
Controlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR). J Biol Chem (2013) 1.19
Lipid droplet metabolism. Curr Opin Clin Nutr Metab Care (2013) 0.87
Desorption electrospray ionization mass spectrometry reveals lipid metabolism of individual oocytes and embryos. PLoS One (2013) 0.85
Accumulation of squalene in a microalga Chlamydomonas reinhardtii by genetic modification of squalene synthase and squalene epoxidase genes. PLoS One (2015) 0.80
Monoubiquitination of ancient ubiquitous protein 1 promotes lipid droplet clustering. PLoS One (2013) 0.80
The DNA sequence of the human X chromosome. Nature (2005) 6.97
Gene-expression profiling of peripheral blood mononuclear cells in sepsis. Crit Care Med (2009) 2.85
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast. J Cell Biol (2008) 2.85
Molecular identification of high and low affinity receptors for nicotinic acid. J Biol Chem (2003) 2.52
Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice. PLoS One (2008) 2.51
ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-I. Arterioscler Thromb Vasc Biol (2005) 2.46
Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proc Natl Acad Sci U S A (2004) 2.45
The use of gene-expression profiling to identify candidate genes in human sepsis. Am J Respir Crit Care Med (2007) 2.12
Complex cellular responses to reactive oxygen species. Trends Cell Biol (2005) 2.09
Gene-expression profiling of gram-positive and gram-negative sepsis in critically ill patients. Crit Care Med (2008) 2.04
Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux. Arterioscler Thromb Vasc Biol (2004) 1.92
Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites. J Cell Biol (2011) 1.84
Vps20p and Vta1p interact with Vps4p and function in multivesicular body sorting and endosomal transport in Saccharomyces cerevisiae. J Cell Sci (2003) 1.73
A role for phosphatidic acid in the formation of "supersized" lipid droplets. PLoS Genet (2011) 1.69
Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes. Mol Cell Biol (2007) 1.59
Reactive oxygen species and yeast apoptosis. Biochim Biophys Acta (2008) 1.57
The Akt-SREBP nexus: cell signaling meets lipid metabolism. Trends Endocrinol Metab (2010) 1.55
The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain. Pain (2008) 1.54
Clade B HIV-1 superinfection with wild-type virus after primary infection with drug-resistant clade B virus. AIDS (2003) 1.52
Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: a link between a key cell proliferative pathway and membrane synthesis. Mol Biol Cell (2006) 1.49
A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking. J Cell Biol (2011) 1.48
Reducing safety-related drug attrition: the use of in vitro pharmacological profiling. Nat Rev Drug Discov (2012) 1.47
Seipin ablation in mice results in severe generalized lipodystrophy. Hum Mol Genet (2011) 1.46
Sterol regulators of cholesterol homeostasis and beyond: the oxysterol hypothesis revisited and revised. Prog Lipid Res (2008) 1.46
Effect of venipuncture quality on thromboelastography. J Vet Emerg Crit Care (San Antonio) (2012) 1.38
Systematic analysis of sporulation phenotypes in 624 non-lethal homozygous deletion strains of Saccharomyces cerevisiae. Yeast (2002) 1.33
Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes. Nat Commun (2013) 1.31
Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation. PLoS Genet (2011) 1.30
Toward one step analysis of cellular lipidomes using liquid chromatography coupled with mass spectrometry: application to Saccharomyces cerevisiae and Schizosaccharomyces pombe lipidomics. Mol Biosyst (2010) 1.28
PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA. Arterioscler Thromb Vasc Biol (2010) 1.24
OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages. J Biol Chem (2007) 1.23
SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR. Biochem J (2006) 1.22
Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short chain fatty acids. J Biol Chem (2008) 1.21
GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils. Cell Res (2011) 1.21
Controlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR). J Biol Chem (2013) 1.19
Cholesterol-dependent degradation of squalene monooxygenase, a control point in cholesterol synthesis beyond HMG-CoA reductase. Cell Metab (2011) 1.18
Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis. Am J Pathol (2002) 1.18
Population structure of Helicobacter pylori among ethnic groups in Malaysia: recent acquisition of the bacterium by the Malay population. BMC Microbiol (2009) 1.17
Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55. Mol Endocrinol (2011) 1.17
Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis. J Lipid Res (2011) 1.14
Conditions of endoplasmic reticulum stress stimulate lipid droplet formation in Saccharomyces cerevisiae. Biochem J (2009) 1.14
Schizosaccharomyces pombe cells deficient in triacylglycerols synthesis undergo apoptosis upon entry into the stationary phase. J Biol Chem (2003) 1.13
Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae. Mol Biol Cell (2004) 1.12
Seipin, adipogenesis and lipid droplets. Trends Endocrinol Metab (2011) 1.12
Quantitation of (a)symmetric inheritance of functional and of oxidatively damaged mitochondrial aconitase in the cell division of old yeast mother cells. Exp Gerontol (2010) 1.11
Redox control of cell proliferation. Trends Cell Biol (2012) 1.11
Expressing functional siRNAs in mammalian cells using convergent transcription. BMC Biotechnol (2003) 1.11
Attenuation of the lysosomal death pathway by lysosomal cholesterol accumulation. Am J Pathol (2011) 1.10
Involvement of oxidative stress response genes in redox homeostasis, the level of reactive oxygen species, and ageing in Saccharomyces cerevisiae. FEMS Yeast Res (2005) 1.09
The high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae is the major determinant of cAMP levels in stationary phase: involvement of different branches of the Ras-cyclic AMP pathway in stress responses. Biochem Biophys Res Commun (2005) 1.08
Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis. J Biol Chem (2007) 1.08
Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors. J Biomol Screen (2013) 1.08
Identification of the major functional proteins of prokaryotic lipid droplets. J Lipid Res (2011) 1.07
Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae. BMC Genomics (2009) 1.07
Characterization of the putative maltose transporters encoded by YDL247w and YJR160c. Yeast (2002) 1.07
Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress. Yeast (2002) 1.06
Structure of Osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins. Structure (2013) 1.05
Site-directed, Ligase-Independent Mutagenesis (SLIM) for highly efficient mutagenesis of plasmids greater than 8kb. J Microbiol Methods (2008) 1.05
G protein-coupled receptors for free fatty acids. Cell Signal (2006) 1.05
The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55. J Biol Chem (2012) 1.05
Discovery of 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain. J Med Chem (2007) 1.03
The thioredoxin-thioredoxin reductase system can function in vivo as an alternative system to reduce oxidized glutathione in Saccharomyces cerevisiae. J Biol Chem (2009) 1.03
Human multidrug resistance associated protein 4 confers resistance to camptothecins. Pharm Res (2005) 1.01
Changes in reactive oxygen species begin early during replicative aging of Saccharomyces cerevisiae cells. Free Radic Biol Med (2011) 1.01
A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products. Biochem J (2012) 1.01
The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation. Atherosclerosis (2007) 1.00
Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist. Mol Pharmacol (2007) 1.00
The redox regulation of intermediary metabolism by a superoxide-aconitase rheostat. Bioessays (2004) 0.99
An essential role of Hrs/Vps27 in endosomal cholesterol trafficking. Cell Rep (2012) 0.99
The origin of multiple B mating specificities in Coprinus cinereus. Genetics (2005) 0.98
The role of respiration, reactive oxygen species and oxidative stress in mother cell-specific ageing of yeast strains defective in the RAS signalling pathway. FEMS Yeast Res (2004) 0.98
Coupling of the transcriptional regulation of glutathione biosynthesis to the availability of glutathione and methionine via the Met4 and Yap1 transcription factors. J Biol Chem (2003) 0.98
Desmosterol and DHCR24: unexpected new directions for a terminal step in cholesterol synthesis. Prog Lipid Res (2013) 0.98
Regulation of protein S-thiolation by glutaredoxin 5 in the yeast Saccharomyces cerevisiae. J Biol Chem (2002) 0.98
Genome-wide analysis of sterol-lipid storage and trafficking in Saccharomyces cerevisiae. Eukaryot Cell (2007) 0.98
Characterization of substrate preference for Slc1p and Cst26p in Saccharomyces cerevisiae using lipidomic approaches and an LPAAT activity assay. PLoS One (2010) 0.98
The critical role of glutathione in maintenance of the mitochondrial genome. Free Radic Biol Med (2010) 0.98
Special relationship between sterols and oxygen: were sterols an adaptation to aerobic life? Free Radic Biol Med (2009) 0.98
Yeast genome-wide expression analysis identifies a strong ergosterol and oxidative stress response during the initial stages of an industrial lager fermentation. Appl Environ Microbiol (2003) 0.97
Cu, Zn superoxide dismutase and NADP(H) homeostasis are required for tolerance of endoplasmic reticulum stress in Saccharomyces cerevisiae. Mol Biol Cell (2009) 0.97
Old yellow enzymes protect against acrolein toxicity in the yeast Saccharomyces cerevisiae. Appl Environ Microbiol (2006) 0.97
Rapamycin down-regulates LDL-receptor expression independently of SREBP-2. Biochem Biophys Res Commun (2008) 0.96
Thioredoxins function as deglutathionylase enzymes in the yeast Saccharomyces cerevisiae. BMC Biochem (2010) 0.96
Application of genome-wide expression analysis to identify molecular markers useful in monitoring industrial fermentations. Appl Environ Microbiol (2003) 0.96
Akt phosphorylates Sec24: new clues into the regulation of ER-to-Golgi trafficking. Traffic (2010) 0.96
Molecular analysis of maltotriose transport and utilization by Saccharomyces cerevisiae. Appl Environ Microbiol (2002) 0.96
AAA ATPases regulate membrane association of yeast oxysterol binding proteins and sterol metabolism. EMBO J (2005) 0.96