PubRank

Craig Blackstone

Author PubWeight™ 60.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A class of dynamin-like GTPases involved in the generation of the tubular ER network. Cell 2009 3.88
2 Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology. J Biol Chem 2007 3.86
3 Hereditary spastic paraplegia proteins REEP1, spastin, and atlastin-1 coordinate microtubule interactions with the tubular ER network. J Clin Invest 2010 2.59
4 Atlastin GTPases are required for Golgi apparatus and ER morphogenesis. Hum Mol Genet 2008 2.28
5 Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1. Ann N Y Acad Sci 2010 2.20
6 Intra- and intermolecular domain interactions of the C-terminal GTPase effector domain of the multimeric dynamin-like GTPase Drp1. J Biol Chem 2004 2.19
7 Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B. Nat Struct Mol Biol 2008 2.18
8 L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system. J Biol Chem 2003 2.12
9 Cellular localization, oligomerization, and membrane association of the hereditary spastic paraplegia 3A (SPG3A) protein atlastin. J Biol Chem 2003 2.07
10 Release of OPA1 during apoptosis participates in the rapid and complete release of cytochrome c and subsequent mitochondrial fragmentation. J Biol Chem 2005 2.02
11 Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death. Curr Biol 2005 1.87
12 SPG3A protein atlastin-1 is enriched in growth cones and promotes axon elongation during neuronal development. Hum Mol Genet 2006 1.59
13 A lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division. J Biol Chem 2010 1.56
14 Whole-exome sequencing identifies homozygous AFG3L2 mutations in a spastic ataxia-neuropathy syndrome linked to mitochondrial m-AAA proteases. PLoS Genet 2011 1.54
15 SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle. FASEB J 2009 1.45
16 Targeted high-throughput sequencing identifies mutations in atlastin-1 as a cause of hereditary sensory neuropathy type I. Am J Hum Genet 2010 1.42
17 Traffic accidents: molecular genetic insights into the pathogenesis of the hereditary spastic paraplegias. Pharmacol Ther 2005 1.36
18 Troyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor trafficking. Mol Biol Cell 2007 1.36
19 Further assembly required: construction and dynamics of the endoplasmic reticulum network. EMBO Rep 2010 1.35
20 Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential. Biol Cell 2008 1.33
21 Untangling the web: mechanisms underlying ER network formation. Biochim Biophys Acta 2013 1.23
22 SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis. Mol Biol Cell 2010 1.20
23 Exome sequencing and SNP analysis detect novel compound heterozygosity in fatty acid hydroxylase-associated neurodegeneration. Eur J Hum Genet 2011 1.18
24 Lack of spartin protein in Troyer syndrome: a loss-of-function disease mechanism? Arch Neurol 2008 1.10
25 The Troyer syndrome (SPG20) protein spartin interacts with Eps15. Biochem Biophys Res Commun 2005 1.05
26 Drp1 phosphorylation and mitochondrial regulation. EMBO Rep 2007 1.03
27 Emerging themes of ER organization in the development and maintenance of axons. Curr Opin Neurobiol 2010 1.00
28 Characterization of a novel SPG3A deletion in a French-Canadian family. Ann Neurol 2007 0.99
29 Mitochondria unite to survive. Nat Cell Biol 2011 0.96
30 Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation. J Clin Invest 2014 0.96
31 Spg20-/- mice reveal multimodal functions for Troyer syndrome protein spartin in lipid droplet maintenance, cytokinesis and BMP signaling. Hum Mol Genet 2012 0.92
32 Loss of spastin function results in disease-specific axonal defects in human pluripotent stem cell-based models of hereditary spastic paraplegia. Stem Cells 2014 0.92
33 Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation. Proc Natl Acad Sci U S A 2013 0.91
34 A conserved role for atlastin GTPases in regulating lipid droplet size. Cell Rep 2013 0.91
35 Hereditary spastic paraplegia type 43 (SPG43) is caused by mutation in C19orf12. Hum Mutat 2013 0.90
36 MITD1 is recruited to midbodies by ESCRT-III and participates in cytokinesis. Mol Biol Cell 2012 0.89
37 Interaction of the SPG21 protein ACP33/maspardin with the aldehyde dehydrogenase ALDH16A1. Neurogenetics 2009 0.86
38 STAM adaptor proteins interact with COPII complexes and function in ER-to-Golgi trafficking. Traffic 2008 0.83
39 Targeted disruption of the Mast syndrome gene SPG21 in mice impairs hind limb function and alters axon branching in cultured cortical neurons. Neurogenetics 2010 0.82
40 A progressive, fatal dystonia-Parkinsonism syndrome in a patient with primary immunodeficiency receiving chronic IVIG therapy. Mov Disord 2007 0.81
41 Caspases indirectly regulate cleavage of the mitochondrial fusion GTPase OPA1 in neurons undergoing apoptosis. Brain Res 2008 0.81
42 N-terminal cleavage of the mitochondrial fusion GTPase OPA1 occurs via a caspase-independent mechanism in cerebellar granule neurons exposed to oxidative or nitrosative stress. Brain Res 2012 0.78
43 Rab10 joins the ER social network. Nat Cell Biol 2013 0.78
44 SUMO wrestling with Drp1 at mitochondria. EMBO J 2013 0.77
45 Novel Compound Heterozygous Spatacsin Mutations in a Greek Kindred with Hereditary Spastic Paraplegia SPG11 and Dementia. Neurodegener Dis 2016 0.76