Published in Biophys J on October 02, 2012
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Treating entropy and conformational changes in implicit solvent simulations of small molecules. J Phys Chem B (2008) 1.47
Stepwise protein folding at near amino acid resolution by hydrogen exchange and mass spectrometry. Proc Natl Acad Sci U S A (2013) 1.34
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Protein-DNA chimeras for single molecule mechanical folding studies with the optical tweezers. Eur Biophys J (2008) 1.29
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Exploring subdomain cooperativity in T4 lysozyme II: uncovering the C-terminal subdomain as a hidden intermediate in the kinetic folding pathway. Protein Sci (2007) 1.21
Destabilization of the Escherichia coli RNase H kinetic intermediate: switching between a two-state and three-state folding mechanism. J Mol Biol (2004) 1.19
Exploring subdomain cooperativity in T4 lysozyme I: structural and energetic studies of a circular permutant and protein fragment. Protein Sci (2007) 1.17
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Quantitative determination of protein stability and ligand binding by pulse proteolysis. Curr Protoc Protein Sci (2006) 1.07
On the precision of experimentally determined protein folding rates and phi-values. Protein Sci (2006) 1.06
Experimental evaluation of topological parameters determining protein-folding rates. Proc Natl Acad Sci U S A (2002) 1.05
Direct observation of a force-induced switch in the anisotropic mechanical unfolding pathway of a protein. Proc Natl Acad Sci U S A (2012) 1.05
Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation. J Mol Biol (2002) 1.04
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Comparison of the folding processes of T. thermophilus and E. coli ribonucleases H. J Mol Biol (2002) 1.01
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Time step rescaling recovers continuous-time dynamical properties for discrete-time Langevin integration of nonequilibrium systems. J Phys Chem B (2014) 0.97
Dynamical fingerprints for probing individual relaxation processes in biomolecular dynamics with simulations and kinetic experiments. Proc Natl Acad Sci U S A (2011) 0.96
Hydrogen exchange and ligand binding: ligand-dependent and ligand-independent protection in the Src SH3 domain. Protein Sci (2004) 0.94
Structure, stability, and folding of ribonuclease H1 from the moderately thermophilic Chlorobium tepidum: comparison with thermophilic and mesophilic homologues. Biochemistry (2009) 0.94
Nonequilibrium candidate Monte Carlo is an efficient tool for equilibrium simulation. Proc Natl Acad Sci U S A (2011) 0.93
Native state energetics of the Src SH2 domain: evidence for a partially structured state in the denatured ensemble. Protein Sci (2006) 0.92
MOPED: method for optimizing physical energy parameters using decoys. J Comput Chem (2003) 0.91
On the mechanism of chaperone activity of the small heat-shock protein of Methanococcus jannaschii. Proc Natl Acad Sci U S A (2003) 0.90
A hinge region cis-proline in ribonuclease A acts as a conformational gatekeeper for C-terminal domain swapping. J Mol Biol (2010) 0.89
Analysis of the stability of multimeric proteins by effective DeltaG and effective m-values. Protein Sci (2004) 0.89
Propagation of a single destabilizing mutation throughout the Escherichia coli ribonuclease HI native state. Protein Sci (2002) 0.87
Identifying ligand binding sites and poses using GPU-accelerated Hamiltonian replica exchange molecular dynamics. J Comput Aided Mol Des (2013) 0.87
Structural and kinetic mapping of side-chain exposure onto the protein energy landscape. Proc Natl Acad Sci U S A (2011) 0.87
The mechanical properties of PCNA: implications for the loading and function of a DNA sliding clamp. Biophys J (2010) 0.87
The folding trajectory of RNase H is dominated by its topology and not local stability: a protein engineering study of variants that fold via two-state and three-state mechanisms. J Mol Biol (2009) 0.87
DNA molecular handles for single-molecule protein-folding studies by optical tweezers. Methods Mol Biol (2011) 0.86
A single mutation at residue 25 populates the folding intermediate of E. coli RNase H and reveals a highly dynamic partially folded ensemble. J Mol Biol (2009) 0.86
Kinetic evidence for a two-stage mechanism of protein denaturation by guanidinium chloride. Proc Natl Acad Sci U S A (2014) 0.85
Protein folding and unfolding under force. Biopolymers (2013) 0.84
Hydrogen-exchange strategies applied to energetics of intermediate processes in protein folding. Methods Enzymol (2004) 0.84
Systematic errors in isothermal titration calorimetry: concentrations and baselines. Anal Biochem (2011) 0.83
Propensity for C-terminal domain swapping correlates with increased regional flexibility in the C-terminus of RNase A. Protein Sci (2011) 0.82
Identification of residual structure in the unfolded state of ribonuclease H1 from the moderately thermophilic Chlorobium tepidum: comparison with thermophilic and mesophilic homologues. Biochemistry (2010) 0.82
Protein-protein binding affinities by pulse proteolysis: application to TEM-1/BLIP protein complexes. Protein Sci (2010) 0.78
Mono and dual cofactor dependence of human cystathionine β-synthase enzyme variants in vivo and in vitro. G3 (Bethesda) (2013) 0.77
Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin. J Clin Invest (2016) 0.76
Single molecule conformational memory extraction: p5ab RNA hairpin. J Phys Chem B (2014) 0.75
Uncertainty estimation. Adv Exp Med Biol (2014) 0.75
Folding and binding. Curr Opin Struct Biol (2013) 0.75
Estimation and validation of Markov models. Adv Exp Med Biol (2014) 0.75
Structural properties of the histidine-containing loop in HIV-1 RNase H. Biophys Chem (2002) 0.75