PubRank

Guy G Poirier

Author PubWeight™ 106.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 2002 8.41
2 PARP inhibition: PARP1 and beyond. Nat Rev Cancer 2010 6.70
3 Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Mol Cell 2007 4.58
4 Human Proteinpedia enables sharing of human protein data. Nat Biotechnol 2008 4.21
5 Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death. Proc Natl Acad Sci U S A 2006 3.47
6 Poly(ADP-ribose) (PAR) polymer is a death signal. Proc Natl Acad Sci U S A 2006 3.41
7 Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes. Nucleic Acids Res 2008 2.70
8 PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites. J Biol Chem 2007 2.62
9 Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase. J Biol Chem 2002 2.56
10 Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality. Proc Natl Acad Sci U S A 2004 2.20
11 Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death. J Neurosci 2004 2.17
12 PARP-1, a determinant of cell survival in response to DNA damage. Exp Hematol 2003 2.08
13 Failure of iniparib to inhibit poly(ADP-Ribose) polymerase in vitro. Clin Cancer Res 2012 1.87
14 Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents. J Biol Chem 2007 1.80
15 Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos). Sci Signal 2011 1.73
16 Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4. Virology 2006 1.47
17 A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins. Biochem J 2003 1.45
18 Poly(ADP-ribosyl)ated chromatin domains: access granted. J Cell Sci 2004 1.42
19 Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage. Proc Natl Acad Sci U S A 2011 1.42
20 tej defines a role for poly(ADP-ribosyl)ation in establishing period length of the arabidopsis circadian oscillator. Dev Cell 2002 1.40
21 Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death. Nat Med 2011 1.36
22 The expanding role of poly(ADP-ribose) metabolism: current challenges and new perspectives. Curr Opin Cell Biol 2006 1.35
23 Targeting poly(ADP-ribosyl)ation: a promising approach in cancer therapy. Trends Mol Med 2005 1.29
24 Enhanced killing of cancer cells by poly(ADP-ribose) polymerase inhibitors and topoisomerase I inhibitors reflects poisoning of both enzymes. J Biol Chem 2011 1.29
25 PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks. Nucleic Acids Res 2012 1.28
26 Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress. Nucleic Acids Res 2012 1.25
27 CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage. Nucleic Acids Res 2012 1.16
28 Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry. Proteome Sci 2010 1.14
29 Proteomic investigation of phosphorylation sites in poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase. J Proteome Res 2009 1.14
30 Mapping PARP-1 auto-ADP-ribosylation sites by liquid chromatography-tandem mass spectrometry. J Proteome Res 2013 1.11
31 Comparative proteome analysis of human epithelial ovarian cancer. Proteome Sci 2007 1.08
32 Proteome profiling of human epithelial ovarian cancer cell line TOV-112D. Mol Cell Biochem 2005 1.06
33 Poly(ADP-ribose) polymerase-1 is a positive regulator of the p53-mediated G1 arrest response following ionizing radiation. J Biol Chem 2003 1.05
34 An SNP in an ultraconserved regulatory element affects Dlx5/Dlx6 regulation in the forebrain. Development 2010 1.04
35 Human papillomavirus E1 helicase interacts with the WD repeat protein p80 to promote maintenance of the viral genome in keratinocytes. J Virol 2007 1.04
36 Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription. Biochem J 2008 1.03
37 Polycomb repressive complex 2 contributes to DNA double-strand break repair. Cell Cycle 2013 0.98
38 RT-PSM, a real-time program for peptide-spectrum matching with statistical significance. Rapid Commun Mass Spectrom 2006 0.98
39 Dynamic relocation of poly(ADP-ribose) glycohydrolase isoforms during radiation-induced DNA damage. Biochim Biophys Acta 2005 0.97
40 Assessment of PARP-3 distribution in tissues of cynomolgous monkeys. J Histochem Cytochem 2009 0.96
41 Comparative proteomics analyses reveal a potential biomarker for the detection of vancomycin-intermediate Staphylococcus aureus strains. J Proteome Res 2007 0.96
42 PARPs database: a LIMS systems for protein-protein interaction data mining or laboratory information management system. BMC Bioinformatics 2007 0.95
43 Alteration of poly(ADP-ribose) glycohydrolase nucleocytoplasmic shuttling characteristics upon cleavage by apoptotic proteases. Biol Cell 2003 0.95
44 Quality assessment of peptide tandem mass spectra. BMC Bioinformatics 2008 0.94
45 PARP-1-induced cell death through inhibition of the MEK/ERK pathway in MNNG-treated HeLa cells. Apoptosis 2007 0.92
46 PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent. PLoS One 2012 0.90
47 Poly(ADP-ribose) degradation by post-nuclear extracts from human cells. Biochimie 2002 0.90
48 Poly(ADP-ribose) glycohydrolase is a component of the FMRP-associated messenger ribonucleoparticles. Biochem J 2005 0.89
49 Proteomic and genomic analyses of antimony resistant Leishmania infantum mutant. PLoS One 2013 0.89
50 Quantitative proteomics and dynamic imaging reveal that G3BP-mediated stress granule assembly is poly(ADP-ribose)-dependent following exposure to MNNG-induced DNA alkylation. J Cell Sci 2012 0.89
51 Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples. J Proteome Res 2011 0.88
52 Transcription. Gene expression needs a break to unwind before carrying on. Science 2006 0.87
53 Structural biology. PARP-1 activation--bringing the pieces together. Science 2012 0.86
54 Proteomic analysis of enriched lysosomes at early phase of camptothecin-induced apoptosis in human U-937 cells. J Proteomics 2009 0.86
55 Experimental and bioinformatic approaches for interrogating protein-protein interactions to determine protein function. J Mol Endocrinol 2005 0.85
56 Nonisotopic methods for determination of poly(ADP-ribose) levels and detection of poly(ADP-ribose) polymerase. Curr Protoc Cell Biol 2004 0.85
57 Effect of potato suberin on Streptomyces scabies proteome. Mol Plant Pathol 2008 0.85
58 Environmental exposure to polychlorinated biphenyls and placental CYP1A1 activity in Inuit women from northern Québec. Environ Health Perspect 2002 0.84
59 Ensconsin/Map7 promotes microtubule growth and centrosome separation in Drosophila neural stem cells. J Cell Biol 2014 0.83
60 A novel approach to denoising ion trap tandem mass spectra. Proteome Sci 2009 0.82
61 A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development. PLoS One 2011 0.81
62 Proteomic characterization of mouse cytosolic and membrane prostate fractions: high levels of free SUMO peptides are androgen-regulated. J Proteome Res 2008 0.81
63 The human UGT1A3 enzyme conjugates norursodeoxycholic acid into a C23-ester glucuronide in the liver. J Biol Chem 2009 0.81
64 Affinity-based assays for the identification and quantitative evaluation of noncovalent poly(ADP-ribose)-binding proteins. Methods Mol Biol 2011 0.80
65 A conserved initiator element on the mammalian poly(ADP-ribose) polymerase-1 promoters, in combination with flanking core elements, is necessary to obtain high transcriptional activity. Biochim Biophys Acta 2004 0.80
66 Insulin-dependent phosphorylation of DPP IV in liver. Evidence for a role of compartmentalized c-Src. FEBS J 2006 0.79
67 Proteomics reveals a switch in CDK1-associated proteins upon M-phase exit during the Xenopus laevis oocyte to embryo transition. Int J Biochem Cell Biol 2011 0.79
68 Quality assessment of tandem mass spectra using support vector machine (SVM). BMC Bioinformatics 2009 0.78
69 Mass spectrometry-based functional proteomics of poly(ADP-ribose) polymerase-1. Expert Rev Proteomics 2011 0.78
70 Low hepatic ethoxyresorufin-O-deethylase activity correlates with high organochlorine concentrations in Atlantic tomcod from the Canadian east coast. Environ Toxicol Chem 2005 0.77
71 Niacin deficiency decreases bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats. J Nutr 2002 0.77
72 PARP1 parylation promotes silent locus transmission in the nucleolus: the suspicion confirmed. Mol Cell 2012 0.77
73 Differential proteomic screen to evidence proteins ubiquitinated upon mitotic exit in cell-free extract of Xenopus laevis embryos. J Proteome Res 2008 0.76
74 Focus on computational proteomics. Proteomics 2011 0.75
75 In-situ analysis of cellular poly(ADP-ribose) production in scrapie-infected mouse neuroblastoma cells. Histochem J 2003 0.75
76 Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats. J Nutr 2002 0.75