Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
|
Nature
|
2011
|
13.23
|
2
|
The genome of the kinetoplastid parasite, Leishmania major.
|
Science
|
2005
|
8.64
|
3
|
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
|
Nat Genet
|
2010
|
8.48
|
4
|
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
|
Nat Genet
|
2013
|
7.44
|
5
|
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.
|
Nat Genet
|
2011
|
5.56
|
6
|
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.
|
Nat Genet
|
2009
|
4.61
|
7
|
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.
|
Nat Genet
|
2010
|
4.42
|
8
|
BCG-induced increase in interferon-gamma response to mycobacterial antigens and efficacy of BCG vaccination in Malawi and the UK: two randomised controlled studies.
|
Lancet
|
2002
|
3.75
|
9
|
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.
|
Nat Genet
|
2012
|
3.40
|
10
|
Genetic susceptibility to infectious diseases: big is beautiful, but will bigger be even better?
|
Lancet Infect Dis
|
2006
|
1.56
|
11
|
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.
|
Nat Genet
|
2012
|
1.52
|
12
|
IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection.
|
J Immunol
|
2005
|
1.48
|
13
|
Interleukin-10, polymorphism in SLC11A1 (formerly NRAMP1), and susceptibility to tuberculosis.
|
J Infect Dis
|
2002
|
1.42
|
14
|
IL6 -174 G/C promoter polymorphism influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil.
|
J Infect Dis
|
2006
|
1.38
|
15
|
P2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages.
|
J Immunol
|
2010
|
1.33
|
16
|
Genetic and epigenetic factors at COL2A1 and ABCA4 influence clinical outcome in congenital toxoplasmosis.
|
PLoS One
|
2008
|
1.32
|
17
|
Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.
|
Nat Genet
|
2013
|
1.15
|
18
|
Slc11a1, formerly Nramp1, is expressed in dendritic cells and influences major histocompatibility complex class II expression and antigen-presenting cell function.
|
Infect Immun
|
2007
|
1.11
|
19
|
Genetic predisposition to self-curing infection with the protozoan Leishmania chagasi: a genomewide scan.
|
J Infect Dis
|
2007
|
1.09
|
20
|
Geographic information systems and applied spatial statistics are efficient tools to study Hansen's disease (leprosy) and to determine areas of greater risk of disease.
|
Am J Trop Med Hyg
|
2010
|
1.07
|
21
|
Association between SLC11A1 (formerly NRAMP1) and the risk of sarcoidosis in Poland.
|
Eur J Hum Genet
|
2005
|
1.06
|
22
|
Y chromosome lineage- and village-specific genes on chromosomes 1p22 and 6q27 control visceral leishmaniasis in Sudan.
|
PLoS Genet
|
2007
|
1.06
|
23
|
From genome to vaccines for leishmaniasis: screening 100 novel vaccine candidates against murine Leishmania major infection.
|
Vaccine
|
2005
|
1.02
|
24
|
Genome-wide association study to identify the genetic determinants of otitis media susceptibility in childhood.
|
PLoS One
|
2012
|
1.02
|
25
|
TLR1/2 activation during heterologous prime-boost vaccination (DNA-MVA) enhances CD8+ T Cell responses providing protection against Leishmania (Viannia).
|
PLoS Negl Trop Dis
|
2011
|
1.00
|
26
|
CXCR1 and SLC11A1 polymorphisms affect susceptibility to cutaneous leishmaniasis in Brazil: a case-control and family-based study.
|
BMC Med Genet
|
2010
|
0.99
|
27
|
HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite.
|
Blood
|
2007
|
0.99
|
28
|
Mycobacterial purified protein derivatives stimulate innate immunity: Malawians show enhanced tumor necrosis factor alpha, interleukin-1beta (IL-1beta), and IL-10 responses compared to those of adolescents in the United Kingdom.
|
Infect Immun
|
2004
|
0.99
|
29
|
Slc11a1-mediated resistance to Salmonella enterica serovar Typhimurium and Leishmania donovani infections does not require functional inducible nitric oxide synthase or phagocyte oxidase activity.
|
J Leukoc Biol
|
2004
|
0.98
|
30
|
Unraveling the genetics of otitis media: from mouse to human and back again.
|
Mamm Genome
|
2010
|
0.98
|
31
|
Interleukin-4 (IL-4) and IL-10 collude in vaccine failure for novel exacerbatory antigens in murine Leishmania major infection.
|
Infect Immun
|
2005
|
0.97
|
32
|
Genetic admixture in Brazilians exposed to infection with Leishmania chagasi.
|
Ann Hum Genet
|
2009
|
0.96
|
33
|
The -2518bp promoter polymorphism at CCL2/MCP1 influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil.
|
Infect Genet Evol
|
2010
|
0.95
|
34
|
Host genetic and epigenetic factors in toxoplasmosis.
|
Mem Inst Oswaldo Cruz
|
2009
|
0.95
|
35
|
Expression profiling of the Leishmania life cycle: cDNA arrays identify developmentally regulated genes present but not annotated in the genome.
|
Mol Biochem Parasitol
|
2004
|
0.94
|
36
|
Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil.
|
Infect Genet Evol
|
2012
|
0.94
|
37
|
Polymorphism in NOD2, Crohn's disease, and susceptibility to pulmonary tuberculosis.
|
FEMS Immunol Med Microbiol
|
2004
|
0.93
|
38
|
Genetic susceptibility to otitis media in childhood.
|
Laryngoscope
|
2012
|
0.93
|
39
|
Candidate gene analysis of ocular toxoplasmosis in Brazil: evidence for a role for toll-like receptor 9 (TLR9).
|
Mem Inst Oswaldo Cruz
|
2009
|
0.93
|
40
|
Association of a NOD2 gene polymorphism and T-helper 17 cells with presumed ocular toxoplasmosis.
|
J Infect Dis
|
2012
|
0.93
|
41
|
Evolution of differences in transport function in Slc11a family members.
|
J Biol Chem
|
2007
|
0.92
|
42
|
DNA-Salmonella enterica serovar Typhimurium primer-booster vaccination biases towards T helper 1 responses and enhances protection against Leishmania major infection in mice.
|
Infect Immun
|
2004
|
0.92
|
43
|
Sudanese mucosal leishmaniasis: isolation of a parasite within the Leishmania donovani complex that differs genotypically from L. donovani causing classical visceral leishmaniasis.
|
Infect Genet Evol
|
2005
|
0.92
|
44
|
Solute carrier 11a1 (Slc11a1; formerly Nramp1) regulates metabolism and release of iron acquired by phagocytic, but not transferrin-receptor-mediated, iron uptake.
|
Biochem J
|
2002
|
0.92
|
45
|
From genomes to vaccines: Leishmania as a model.
|
Philos Trans R Soc Lond B Biol Sci
|
2002
|
0.92
|
46
|
Polymorphism in IL1B: IL1B-511 association with tuberculosis and decreased lipopolysaccharide-induced IL-1beta in IFN-gamma primed ex-vivo whole blood assay.
|
J Endotoxin Res
|
2005
|
0.91
|
47
|
Cytokine responses to novel antigens in an Indian population living in an area endemic for visceral leishmaniasis.
|
PLoS Negl Trop Dis
|
2012
|
0.90
|
48
|
Genetic and functional evaluation of the role of DLL1 in susceptibility to visceral leishmaniasis in India.
|
Infect Genet Evol
|
2012
|
0.88
|
49
|
Heterologous priming-boosting with DNA and modified vaccinia virus Ankara expressing tryparedoxin peroxidase promotes long-term memory against Leishmania major in susceptible BALB/c Mice.
|
Infect Immun
|
2006
|
0.88
|
50
|
Genetic and functional evaluation of the role of CXCR1 and CXCR2 in susceptibility to visceral leishmaniasis in north-east India.
|
BMC Med Genet
|
2011
|
0.87
|
51
|
A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.
|
Biol Psychiatry
|
2013
|
0.87
|
52
|
No evidence for association between SLC11A1 and visceral leishmaniasis in India.
|
BMC Med Genet
|
2011
|
0.86
|
53
|
Genetic and functional evidence implicating DLL1 as the gene that influences susceptibility to visceral leishmaniasis at chromosome 6q27.
|
J Infect Dis
|
2011
|
0.85
|
54
|
Influence of Slc11a1 (formerly Nramp1) on DSS-induced colitis in mice.
|
J Leukoc Biol
|
2008
|
0.84
|
55
|
Classification and regression tree and spatial analyses reveal geographic heterogeneity in genome wide linkage study of Indian visceral leishmaniasis.
|
PLoS One
|
2010
|
0.84
|
56
|
A prime/boost DNA/Modified vaccinia virus Ankara vaccine expressing recombinant Leishmania DNA encoding TRYP is safe and immunogenic in outbred dogs, the reservoir of zoonotic visceral leishmaniasis.
|
Vaccine
|
2008
|
0.84
|
57
|
Incomplete glycosylation and defective intracellular targeting of mutant solute carrier family 11 member 1 (Slc11a1).
|
Biochem J
|
2004
|
0.84
|
58
|
A genome-wide search for type 2 diabetes susceptibility genes in an extended Arab family.
|
Ann Hum Genet
|
2013
|
0.84
|
59
|
Cytokine responses to novel antigens in a peri-urban population in Brazil exposed to Leishmania infantum chagasi.
|
Am J Trop Med Hyg
|
2012
|
0.83
|
60
|
Candidate gene association study of solute carrier family 11a members 1 (SLC11A1) and 2 (SLC11A2) genes in Alzheimer's disease.
|
Neurosci Lett
|
2005
|
0.81
|
61
|
Genetic and functional evidence for a role for SLC11A1 in susceptibility to otitis media in early childhood in a Western Australian population.
|
Infect Genet Evol
|
2013
|
0.78
|
62
|
Genetic research and aboriginal and Torres Strait Islander Australians.
|
J Bioeth Inq
|
2012
|
0.77
|
63
|
Selection of appropriate serological tests to measure the incidence of natural Leishmania infantum infection during DNA/MVA prime/boost canine vaccine trials.
|
Vet Parasitol
|
2009
|
0.77
|
64
|
Comparative analysis of two slc11 (Nramp) loci in Takifugu rubripes.
|
DNA Cell Biol
|
2004
|
0.76
|
65
|
Genetic and functional evidence for a locus controlling otitis media at chromosome 10q26.3.
|
BMC Med Genet
|
2014
|
0.75
|
66
|
Postgenomic research on leishmaniasis: a critical self-appraisal.
|
Trends Parasitol
|
2008
|
0.75
|