Published in J Biol Chem on October 10, 2007
Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5. J Cell Sci (2009) 2.30
Genetics and visceral leishmaniasis: of mice and man. Parasite Immunol (2009) 1.21
The phage shock protein PspA facilitates divalent metal transport and is required for virulence of Salmonella enterica sv. Typhimurium. Mol Microbiol (2010) 1.18
SMF-1, SMF-2 and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese levels in C. elegans. PLoS One (2009) 1.11
The iron export protein ferroportin 1 is differentially expressed in mouse macrophage populations and is present in the mycobacterial-containing phagosome. J Leukoc Biol (2008) 1.10
Nramp1 and Other Transporters Involved in Metal Withholding during Infection. J Biol Chem (2015) 0.90
Intracellular microbes and haemophagocytosis. Cell Microbiol (2008) 0.87
Elucidation of the functional metal binding profile of a Cd(II)/Pb(II) sensor CmtR(Sc) from Streptomyces coelicolor. Biochemistry (2010) 0.83
Manganese redistribution by calcium-stimulated vesicle trafficking bypasses the need for P-type ATPase function. J Biol Chem (2015) 0.80
Natural history of SLC11 genes in vertebrates: tales from the fish world. BMC Evol Biol (2011) 0.79
Transport proteins promoting Escherichia coli pathogenesis. Microb Pathog (2014) 0.79
Sudden sensorineural hearing loss and polymorphisms in iron homeostasis genes: new insights from a case-control study. Biomed Res Int (2015) 0.77
Dictyostelium Nramp1, which is structurally and functionally similar to mammalian DMT1 transporter, mediates phagosomal iron efflux. J Cell Sci (2015) 0.76
"Pumping iron"-how macrophages handle iron at the systemic, microenvironmental, and cellular levels. Pflugers Arch (2017) 0.75
Duplication and Sub/Neofunctionalization of Malvolio, an Insect Homolog of Nramp, in the Subsocial Beetle Nicrophorus vespilloides. G3 (Bethesda) (2017) 0.75
Positive selection in the SLC11A1 gene in the family Equidae. Immunogenetics (2016) 0.75
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science (2003) 9.17
The genome of the kinetoplastid parasite, Leishmania major. Science (2005) 8.64
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet (2010) 8.48
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet (2011) 5.56
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet (2009) 4.61
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet (2010) 4.42
BCG-induced increase in interferon-gamma response to mycobacterial antigens and efficacy of BCG vaccination in Malawi and the UK: two randomised controlled studies. Lancet (2002) 3.75
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet (2012) 3.40
Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins. EMBO J (2004) 1.92
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells. J Biol Chem (2005) 1.59
Genetic susceptibility to infectious diseases: big is beautiful, but will bigger be even better? Lancet Infect Dis (2006) 1.56
Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing. J Neurosci (2012) 1.52
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52
IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection. J Immunol (2005) 1.48
High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy. Circulation (2012) 1.44
DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet (2013) 1.44
Interleukin-10, polymorphism in SLC11A1 (formerly NRAMP1), and susceptibility to tuberculosis. J Infect Dis (2002) 1.42
IL6 -174 G/C promoter polymorphism influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil. J Infect Dis (2006) 1.38
P2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages. J Immunol (2010) 1.33
Genetic and epigenetic factors at COL2A1 and ABCA4 influence clinical outcome in congenital toxoplasmosis. PLoS One (2008) 1.32
Connexin 43-mediated modulation of polarized cell movement and the directional migration of cardiac neural crest cells. Development (2006) 1.27
Predominance of nontypeable Haemophilus influenzae in children with otitis media following introduction of a 3+0 pneumococcal conjugate vaccine schedule. Vaccine (2011) 1.24
Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy. Proc Natl Acad Sci U S A (2009) 1.19
Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome. Dis Model Mech (2010) 1.18
ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry. Am J Hum Genet (2013) 1.17
Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nat Genet (2013) 1.15
Slc11a1, formerly Nramp1, is expressed in dendritic cells and influences major histocompatibility complex class II expression and antigen-presenting cell function. Infect Immun (2007) 1.11
Genetic predisposition to self-curing infection with the protozoan Leishmania chagasi: a genomewide scan. J Infect Dis (2007) 1.09
Geographic information systems and applied spatial statistics are efficient tools to study Hansen's disease (leprosy) and to determine areas of greater risk of disease. Am J Trop Med Hyg (2010) 1.07
Association between SLC11A1 (formerly NRAMP1) and the risk of sarcoidosis in Poland. Eur J Hum Genet (2005) 1.06
Y chromosome lineage- and village-specific genes on chromosomes 1p22 and 6q27 control visceral leishmaniasis in Sudan. PLoS Genet (2007) 1.06
From genome to vaccines for leishmaniasis: screening 100 novel vaccine candidates against murine Leishmania major infection. Vaccine (2005) 1.02
Genome-wide association study to identify the genetic determinants of otitis media susceptibility in childhood. PLoS One (2012) 1.02
TLR1/2 activation during heterologous prime-boost vaccination (DNA-MVA) enhances CD8+ T Cell responses providing protection against Leishmania (Viannia). PLoS Negl Trop Dis (2011) 1.00
CXCR1 and SLC11A1 polymorphisms affect susceptibility to cutaneous leishmaniasis in Brazil: a case-control and family-based study. BMC Med Genet (2010) 0.99
HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite. Blood (2007) 0.99
Slc11a1-mediated resistance to Salmonella enterica serovar Typhimurium and Leishmania donovani infections does not require functional inducible nitric oxide synthase or phagocyte oxidase activity. J Leukoc Biol (2004) 0.98
Unraveling the genetics of otitis media: from mouse to human and back again. Mamm Genome (2010) 0.98
A role of histone H3 lysine 4 methyltransferase components in endosomal trafficking. J Cell Biol (2009) 0.97
Interleukin-4 (IL-4) and IL-10 collude in vaccine failure for novel exacerbatory antigens in murine Leishmania major infection. Infect Immun (2005) 0.97
Genetic admixture in Brazilians exposed to infection with Leishmania chagasi. Ann Hum Genet (2009) 0.96
The -2518bp promoter polymorphism at CCL2/MCP1 influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil. Infect Genet Evol (2010) 0.95
Host genetic and epigenetic factors in toxoplasmosis. Mem Inst Oswaldo Cruz (2009) 0.95
Expression profiling of the Leishmania life cycle: cDNA arrays identify developmentally regulated genes present but not annotated in the genome. Mol Biochem Parasitol (2004) 0.94
Interrogating congenital heart defects with noninvasive fetal echocardiography in a mouse forward genetic screen. Circ Cardiovasc Imaging (2013) 0.94
Ventricular rotation is independent of cardiac looping: a study in mice with situs inversus totalis using speckle-tracking echocardiography. J Am Soc Echocardiogr (2010) 0.94
Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil. Infect Genet Evol (2012) 0.94
Mouse model of heterotaxy with single ventricle spectrum of cardiac anomalies. Pediatr Res (2008) 0.93
Genetic susceptibility to otitis media in childhood. Laryngoscope (2012) 0.93
Polymorphism in NOD2, Crohn's disease, and susceptibility to pulmonary tuberculosis. FEMS Immunol Med Microbiol (2004) 0.93
Candidate gene analysis of ocular toxoplasmosis in Brazil: evidence for a role for toll-like receptor 9 (TLR9). Mem Inst Oswaldo Cruz (2009) 0.93
Association of a NOD2 gene polymorphism and T-helper 17 cells with presumed ocular toxoplasmosis. J Infect Dis (2012) 0.93
Microcomputed tomography provides high accuracy congenital heart disease diagnosis in neonatal and fetal mice. Circ Cardiovasc Imaging (2013) 0.92
DNA-Salmonella enterica serovar Typhimurium primer-booster vaccination biases towards T helper 1 responses and enhances protection against Leishmania major infection in mice. Infect Immun (2004) 0.92
Sudanese mucosal leishmaniasis: isolation of a parasite within the Leishmania donovani complex that differs genotypically from L. donovani causing classical visceral leishmaniasis. Infect Genet Evol (2005) 0.92
From genomes to vaccines: Leishmania as a model. Philos Trans R Soc Lond B Biol Sci (2002) 0.92
Solute carrier 11a1 (Slc11a1; formerly Nramp1) regulates metabolism and release of iron acquired by phagocytic, but not transferrin-receptor-mediated, iron uptake. Biochem J (2002) 0.92
Polymorphism in IL1B: IL1B-511 association with tuberculosis and decreased lipopolysaccharide-induced IL-1beta in IFN-gamma primed ex-vivo whole blood assay. J Endotoxin Res (2005) 0.91
Murine CENPF interacts with syntaxin 4 in the regulation of vesicular transport. J Cell Sci (2008) 0.91
Cytokine responses to novel antigens in an Indian population living in an area endemic for visceral leishmaniasis. PLoS Negl Trop Dis (2012) 0.90
Heterologous priming-boosting with DNA and modified vaccinia virus Ankara expressing tryparedoxin peroxidase promotes long-term memory against Leishmania major in susceptible BALB/c Mice. Infect Immun (2006) 0.88
Genetic and functional evaluation of the role of DLL1 in susceptibility to visceral leishmaniasis in India. Infect Genet Evol (2012) 0.88
Genetic and functional evaluation of the role of CXCR1 and CXCR2 in susceptibility to visceral leishmaniasis in north-east India. BMC Med Genet (2011) 0.87
A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation. Biol Psychiatry (2013) 0.87
No evidence for association between SLC11A1 and visceral leishmaniasis in India. BMC Med Genet (2011) 0.86
Genetic and functional evidence implicating DLL1 as the gene that influences susceptibility to visceral leishmaniasis at chromosome 6q27. J Infect Dis (2011) 0.85
Influence of Slc11a1 (formerly Nramp1) on DSS-induced colitis in mice. J Leukoc Biol (2008) 0.84
Classification and regression tree and spatial analyses reveal geographic heterogeneity in genome wide linkage study of Indian visceral leishmaniasis. PLoS One (2010) 0.84
Incomplete glycosylation and defective intracellular targeting of mutant solute carrier family 11 member 1 (Slc11a1). Biochem J (2004) 0.84
A genome-wide search for type 2 diabetes susceptibility genes in an extended Arab family. Ann Hum Genet (2013) 0.84
Calsenilin and CALP interact with the cytoplasmic tail of UDP-Gal:GA2/GM2/GD2 beta-1,3-galactosyltransferase. Biochem J (2008) 0.83
Cytokine responses to novel antigens in a peri-urban population in Brazil exposed to Leishmania infantum chagasi. Am J Trop Med Hyg (2012) 0.83
Application of a decision-support tool to assess pooling strategies in perfusion culture processes under uncertainty. Biotechnol Prog (2005) 0.82
Decision-support software for the industrial-scale chromatographic purification of antibodies. Biotechnol Prog (2007) 0.81
Candidate gene association study of solute carrier family 11a members 1 (SLC11A1) and 2 (SLC11A2) genes in Alzheimer's disease. Neurosci Lett (2005) 0.81
Albuminuria associated with CD2AP knockout mice is primarily due to dysfunction of the renal degradation pathway processing of filtered albumin. FEBS Lett (2013) 0.80
A comparison of adverse reaction rates for PAS C versus plasma platelet units. Transfusion (2014) 0.79
Genetic and functional evidence for a role for SLC11A1 in susceptibility to otitis media in early childhood in a Western Australian population. Infect Genet Evol (2013) 0.78
Global Sensitivity Analysis for the determination of parameter importance in bio-manufacturing processes. Biotechnol Appl Biochem (2008) 0.78
Separation of immunoglobulin G precipitate from contaminating proteins using microfiltration. Biotechnol Appl Biochem (2004) 0.77
Detection and quantification of affinity ligand leaching and specific antibody fragment concentration within chromatographic fractions using surface plasmon resonance. Biotechnol Appl Biochem (2007) 0.77
TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells. Elife (2013) 0.77
The integrated simulation and assessment of the impacts of process change in biotherapeutic antibody production. Biotechnol Prog (2006) 0.77
Genetic research and aboriginal and Torres Strait Islander Australians. J Bioeth Inq (2012) 0.77
Selection of appropriate serological tests to measure the incidence of natural Leishmania infantum infection during DNA/MVA prime/boost canine vaccine trials. Vet Parasitol (2009) 0.77
Optimal conditions for the papain digestion of polyclonal ovine IgG for the production of bio-therapeutic Fab fragments. Biotechnol Appl Biochem (2005) 0.76
Optimised affinity purification of polyclonal antibodies from hyper immunised ovine serum using a synthetic Protein A adsorbent, MAbsorbent A2P. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 0.76
Comparative analysis of two slc11 (Nramp) loci in Takifugu rubripes. DNA Cell Biol (2004) 0.76
Shared scheme for assessing drugs for multiple sclerosis: cost effective provision of effective treatments for multiple sclerosis. BMJ (2003) 0.76
Activation of H(+)-ATPase by glucose in Saccharomyces cerevisiae involves a membrane serine protease. Biochim Biophys Acta (2013) 0.76
Evaluation and management of scoliosis. J Pediatr Health Care (2003) 0.76