Published in Mol Psychiatry on November 13, 2012
Neural and behavioral effects of a novel mu opioid receptor antagonist in binge-eating obese people. Biol Psychiatry (2012) 0.96
Attenuation of cocaine and heroin seeking by μ-opioid receptor antagonism. Psychopharmacology (Berl) (2013) 0.94
Mu-opioid stimulation in rat prefrontal cortex engages hypothalamic orexin/hypocretin-containing neurons, and reveals dissociable roles of nucleus accumbens and hypothalamus in cortically driven feeding. J Neurosci (2013) 0.88
Opposing neural effects of naltrexone on food reward and aversion: implications for the treatment of obesity. Psychopharmacology (Berl) (2014) 0.85
Obesity at conception programs the opioid system in the offspring brain. Neuropsychopharmacology (2013) 0.82
Involvement of Endogenous Enkephalins and β-Endorphin in Feeding and Diet-Induced Obesity. Neuropsychopharmacology (2015) 0.80
The novel mu-opioid antagonist, GSK1521498, reduces ethanol consumption in C57BL/6J mice. Psychopharmacology (Berl) (2015) 0.79
Convergent dysregulation of frontal cortical cognitive and reward systems in eating disorders. Med Sci Monit (2013) 0.79
The role of the opioid system in binge eating disorder. CNS Spectr (2015) 0.79
Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands. Bioorg Med Chem (2015) 0.78
Cognitive biases in binge eating disorder: the hijacking of decision making. CNS Spectr (2015) 0.78
Amylin receptor signaling in the nucleus accumbens negatively modulates μ-opioid-driven feeding. Neuropsychopharmacology (2014) 0.77
The effects of alcohol on the pharmacokinetics and pharmacodynamics of the selective mu-opioid receptor antagonist GSK1521498 in healthy subjects. J Clin Pharmacol (2013) 0.77
Sweet taste pleasantness is modulated by morphine and naltrexone. Psychopharmacology (Berl) (2016) 0.76
Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype. Neuropsychopharmacology (2016) 0.76
Neurobiological features of binge eating disorder. CNS Spectr (2015) 0.76
Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains. Psychopharmacology (Berl) (2014) 0.76
The Novel μ-Opioid Receptor Antagonist GSK1521498 Decreases Both Alcohol Seeking and Drinking: Evidence from a New Preclinical Model of Alcohol Seeking. Neuropsychopharmacology (2015) 0.76
Dopamine and Opioid Neurotransmission in Behavioral Addictions: A Comparative PET Study in Pathological Gambling and Binge Eating. Neuropsychopharmacology (2016) 0.75
Feeding-modulatory effects of mu-opioids in the medial prefrontal cortex: a review of recent findings and comparison to opioid actions in the nucleus accumbens. Psychopharmacology (Berl) (2017) 0.75
Suppressed Fat Appetite after Roux-en-Y Gastric Bypass Surgery Associates with Reduced Brain μ-opioid Receptor Availability in Diet-Induced Obese Male Rats. Front Neurosci (2017) 0.75
Central nervous system biomarkers for antiobesity drug development. Drug Discov Today (2013) 0.75
Studying food reward and motivation in humans. J Vis Exp (2014) 0.75
Opioid Modulation of Value-Based Decision-Making in Healthy Humans. Neuropsychopharmacology (2017) 0.75
An inventory for measuring depression. Arch Gen Psychiatry (1961) 84.61
A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry (1978) 25.54
The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication. Biol Psychiatry (2006) 13.85
Columbia Classification Algorithm of Suicide Assessment (C-CASA): classification of suicidal events in the FDA's pediatric suicidal risk analysis of antidepressants. Am J Psychiatry (2007) 6.35
An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study. Arch Gen Psychiatry (2008) 4.91
Assessment of depression: the depression inventory. Mod Probl Pharmacopsychiatry (1974) 4.76
The assessment of binge eating severity among obese persons. Addict Behav (1982) 4.02
Prevalence and correlates of eating disorders in adolescents. Results from the national comorbidity survey replication adolescent supplement. Arch Gen Psychiatry (2011) 3.73
Hedonic hot spot in nucleus accumbens shell: where do mu-opioids cause increased hedonic impact of sweetness? J Neurosci (2005) 3.10
Reward processing by the opioid system in the brain. Physiol Rev (2009) 2.46
Opioid antagonists for alcohol dependence. Cochrane Database Syst Rev (2010) 2.21
Opioid limbic circuit for reward: interaction between hedonic hotspots of nucleus accumbens and ventral pallidum. J Neurosci (2007) 2.18
The ventral pallidum and hedonic reward: neurochemical maps of sucrose "liking" and food intake. J Neurosci (2005) 2.10
Compulsive overeating as an addiction disorder. A review of theory and evidence. Appetite (2009) 1.88
Randomized controlled trial to investigate the effects of a newly developed formulation of phentermine diffuse-controlled release for obesity. Diabetes Obes Metab (2010) 1.68
Topiramate in the treatment of binge eating disorder associated with obesity: a randomized, placebo-controlled trial. Am J Psychiatry (2003) 1.55
Nucleus accumbens mu-opioids regulate intake of a high-fat diet via activation of a distributed brain network. J Neurosci (2003) 1.54
Opioid peptides and the control of human ingestive behaviour. Neurosci Biobehav Rev (2002) 1.49
Association of µ-opioid receptor (OPRM1) gene polymorphism with response to naltrexone in alcohol dependence: a systematic review and meta-analysis. Addict Biol (2012) 1.46
Naloxone, an opiate blocker, reduces the consumption of sweet high-fat foods in obese and lean female binge eaters. Am J Clin Nutr (1995) 1.16
Comparative effects of a repeated dose regime of diazepam and buspirone on subjective ratings, psychological tests and the EEG. Eur J Clin Pharmacol (1983) 1.16
A randomized, double-blind, placebo-controlled study of sibutramine in the treatment of binge-eating disorder. Arch Gen Psychiatry (2003) 1.15
Differences in delta- and mu-opioid receptor blockade measured by positron emission tomography in naltrexone-treated recently abstinent alcohol-dependent subjects. Neuropsychopharmacology (2007) 1.14
Reliability and construct validity of the Changes in Sexual Functioning Questionnaire short-form (CSFQ-14). J Sex Marital Ther (2005) 1.12
Psychological aspects of severe obesity. Am J Clin Nutr (1992) 1.09
Comparison of binge eating disorder and bulimia nervosa in a community sample. Int J Eat Disord (2001) 1.08
Regulation of ingestive behaviors in the rat by GSK1521498, a novel micro-opioid receptor-selective inverse agonist. J Pharmacol Exp Ther (2011) 1.07
Pharmacological differentiation of opioid receptor antagonists by molecular and functional imaging of target occupancy and food reward-related brain activation in humans. Mol Psychiatry (2011) 1.06
Neuropsychiatric adverse effects of centrally acting antiobesity drugs. CNS Neurosci Ther (2010) 1.04
World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of eating disorders. World J Biol Psychiatry (2011) 1.03
From taste hedonics to motivational drive: central μ-opioid receptors and binge-eating behaviour. Int J Neuropsychopharmacol (2009) 1.03
Inhibition of opioid transmission at the μ-opioid receptor prevents both food seeking and binge-like eating. Neuropsychopharmacology (2012) 1.02
The dose-dependent cognitive effects of acute administration of Ginkgo biloba to healthy young volunteers. Psychopharmacology (Berl) (2000) 1.02
Atomoxetine in the treatment of binge-eating disorder: a randomized placebo-controlled trial. J Clin Psychiatry (2007) 1.01
Structure of the computer-assisted Beck Anxiety Inventory with psychiatric inpatients. J Pers Assess (1993) 1.00
Opioid receptor modulation of hedonic taste preference and food intake: a single-dose safety, pharmacokinetic, and pharmacodynamic investigation with GSK1521498, a novel μ-opioid receptor inverse agonist. J Clin Pharmacol (2011) 0.98
Multiple-dose safety, pharmacokinetics, and pharmacodynamics of the μ-opioid receptor inverse agonist GSK1521498. J Clin Pharmacol (2011) 0.92
Citalopram in the treatment of binge-eating disorder: a placebo-controlled trial. J Clin Psychiatry (2003) 0.92
Increased food and water intake produced in rats by opiate receptor agonists. Psychopharmacology (Berl) (1981) 0.91
Binge eating disorder: the search for better treatments. Am J Psychiatry (2008) 0.91
Review paper: Current strategies in the development of anti-obesity drugs and their safety concerns. Vet Pathol (2009) 0.91
High-dose escitalopram in the treatment of binge-eating disorder with obesity: a placebo-controlled monotherapy trial. Hum Psychopharmacol (2008) 0.90
A comparison of two approaches to the assessment of binge eating in obesity. Int J Eat Disord (1998) 0.87
Selective actions of central mu and kappa opioid antagonists upon sucrose intake in sham-fed rats. Brain Res (1995) 0.87
Lack of deleterious effects of buspirone on cognition in healthy male volunteers. J Psychopharmacol (2007) 0.83
Naltrexone suppresses hyperphagia induced in the rat by a highly palatable diet. Pharmacol Biochem Behav (1981) 0.83
Prediction of weight loss and regain following dietary, lifestyle, and pharmacologic intervention. Clin Pharmacol Ther (2012) 0.81
Placebo response in binge eating disorder. Int J Eat Disord (2007) 0.81
Modifications of nutrient selection induced by naloxone in rats. Psychopharmacology (Berl) (1981) 0.79
An update in the management of obesity: the weight of CNS targets. Recent Pat CNS Drug Discov (2011) 0.78
Opiate antagonists and eating behavior in humans: a review. J Clin Pharmacol (1992) 0.78
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature (1997) 7.33
Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med (1999) 6.94
Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking. Mol Psychiatry (2008) 6.37
Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension. Nature (2000) 5.86
A specific neural substrate for perceiving facial expressions of disgust. Nature (1997) 5.12
Meta-analysis of regional brain volumes in schizophrenia. Am J Psychiatry (2000) 4.84
Comparative efficacy of adjuvant chemotherapy in patients with Dukes' B versus Dukes' C colon cancer: results from four National Surgical Adjuvant Breast and Bowel Project adjuvant studies (C-01, C-02, C-03, and C-04) J Clin Oncol (1999) 4.79
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene. Nat Genet (1997) 4.77
Reading the mind in cartoons and stories: an fMRI study of 'theory of mind' in verbal and nonverbal tasks. Neuropsychologia (2000) 4.62
A new highly penetrant form of obesity due to deletions on chromosome 16p11.2. Nature (2010) 4.52
A frameshift mutation in MC4R associated with dominantly inherited human obesity. Nat Genet (1998) 4.06
Social intelligence in the normal and autistic brain: an fMRI study. Eur J Neurosci (1999) 3.94
Activation of auditory cortex during silent lipreading. Science (1997) 3.94
LMNA, encoding lamin A/C, is mutated in partial lipodystrophy. Nat Genet (2000) 3.73
Planning for the future by western scrub-jays. Nature (2007) 3.68
Effects of experience and social context on prospective caching strategies by scrub jays. Nature (2001) 3.66
Mapping motor inhibition: conjunctive brain activations across different versions of go/no-go and stop tasks. Neuroimage (2001) 3.51
Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13. Nat Genet (2001) 3.50
A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q. Am J Hum Genet (2001) 3.26
The amygdala theory of autism. Neurosci Biobehav Rev (2000) 3.19
Genetic basis for species vulnerability in the cheetah. Science (1985) 3.16
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. J Clin Invest (2000) 3.10
The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma. EMBO J (1990) 3.05
The functional neuroanatomy of social behaviour: changes in cerebral blood flow when people with autistic disorder process facial expressions. Brain (2000) 3.03
Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers. Am J Pathol (1996) 2.97
The perils of portliness: causes and consequences of visceral adiposity. Diabetes (2000) 2.96
Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle. J Biol Chem (1996) 2.95
Substantia nigra/ventral tegmental reward prediction error disruption in psychosis. Mol Psychiatry (2007) 2.94
Neural responses to facial and vocal expressions of fear and disgust. Proc Biol Sci (1998) 2.93
Genetics of body-weight regulation. Nature (2000) 2.84
Disrupted prediction-error signal in psychosis: evidence for an associative account of delusions. Brain (2007) 2.77
East African cheetahs: evidence for two population bottlenecks? Proc Natl Acad Sci U S A (1987) 2.73
Hypofrontality in attention deficit hyperactivity disorder during higher-order motor control: a study with functional MRI. Am J Psychiatry (1999) 2.72
Development of a homologous transformation system for the human pathogenic fungus Aspergillus fumigatus based on the pyrG gene encoding orotidine 5'-monophosphate decarboxylase. Curr Genet (1998) 2.69
Analysing hippocampal function in transgenic mice: an ethological perspective. Trends Neurosci (1999) 2.66
Linkage of type 2 diabetes to the glucokinase gene. Lancet (1992) 2.64
An activating mutation of AKT2 and human hypoglycemia. Science (2011) 2.60
Low density lipoprotein receptor as a candidate receptor for hepatitis C virus. J Med Virol (1999) 2.52
Catatonia as a psychomotor syndrome: a rating scale and extrapyramidal motor symptoms. Mov Disord (1999) 2.46
Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. Cancer Res (1997) 2.45
Resistin / Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans. Diabetes (2001) 2.43
Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study. Diabetologia (2009) 2.32
Functional frontalisation with age: mapping neurodevelopmental trajectories with fMRI. Neurosci Biobehav Rev (2000) 2.31
The role of randomization in clinical studies: myths and beliefs. J Clin Epidemiol (1999) 2.27
TAp73/Delta Np73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma. Cell Death Differ (2005) 2.25
Dynamic evolution of plant mitochondrial genomes: mobile genes and introns and highly variable mutation rates. Proc Natl Acad Sci U S A (2000) 2.13
Psychological effects of ketamine in healthy volunteers. Phenomenological study. Br J Psychiatry (2006) 2.06
Functional magnetic resonance imaging of synesthesia: activation of V4/V8 by spoken words. Nat Neurosci (2002) 2.05
Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36). Proc Natl Acad Sci U S A (2004) 2.03
Further evidence for an association between non-insulin-dependent diabetes mellitus and chronic hepatitis C virus infection. Hepatology (1999) 2.02
Endoscopic ultrasound as an early diagnostic tool for primary sclerosing cholangitis: a prospective pilot study. Endoscopy (2012) 2.01
Genetic contributions to regional variability in human brain structure: methods and preliminary results. Neuroimage (2002) 2.01
Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent. Int J Obes (Lond) (2009) 1.98
Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas. Cancer Res (1996) 1.97
Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation. J Clin Invest (1997) 1.95
Discriminative and evaluative properties of the activities-specific balance confidence (ABC) scale. J Gerontol A Biol Sci Med Sci (1998) 1.89
Definition of polymorphisms and haplotypes in the interleukin-12B gene: association with IL-12 production but not with Crohn's disease. Genes Immun (2004) 1.89
Segregating the functions of human hippocampus. Proc Natl Acad Sci U S A (1999) 1.86
Dissociating prefrontal and hippocampal function in episodic memory encoding. Nature (1997) 1.84
Treatment outcomes in patients with relapsed and refractory multiple myeloma and high-risk cytogenetics receiving single-agent carfilzomib in the PX-171-003-A1 study. Leukemia (2013) 1.84
Genotype-phenotype relationships in Berardinelli-Seip congenital lipodystrophy. J Med Genet (2002) 1.84
Partial leptin deficiency and human adiposity. Nature (2001) 1.83
Trisomy 13 detection in the first trimester of pregnancy using a chromosome-selective cell-free DNA analysis method. Ultrasound Obstet Gynecol (2012) 1.83
Isolation and characterization of a pigmentless-conidium mutant of Aspergillus fumigatus with altered conidial surface and reduced virulence. Infect Immun (1997) 1.82
Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals. Diabetologia (2009) 1.81
The p70 tumor necrosis factor receptor mediates cytotoxicity. Cell (1992) 1.80
Generic brain activation mapping in functional magnetic resonance imaging: a nonparametric approach. Magn Reson Imaging (1997) 1.78
The cheetah is depauperate in genetic variation. Science (1983) 1.75
Cerebral correlates of preserved cognitive skills in autism: a functional MRI study of embedded figures task performance. Brain (1999) 1.75
Leukocyte count as a predictor of death during remission induction in acute myeloid leukemia. Leuk Lymphoma (2006) 1.74
Genetic factors in human obesity. Obes Rev (2007) 1.72
Regulation of adipose cell number in man. Clin Sci (Lond) (1997) 1.72
Elevated plasma adiponectin in humans with genetically defective insulin receptors. J Clin Endocrinol Metab (2006) 1.71
Dopaminergic drug effects on physiological connectivity in a human cortico-striato-thalamic system. Brain (2003) 1.70
Toward a neurobiology of delusions. Prog Neurobiol (2010) 1.70
Responses of human frontal cortex to surprising events are predicted by formal associative learning theory. Nat Neurosci (2001) 1.68
Response amplification in sensory-specific cortices during crossmodal binding. Neuroreport (1999) 1.68
Volumetric analysis reveals corticospinal tract degeneration and extramotor involvement in ALS. Neurology (2001) 1.68
The 65-kDa carrot microtubule-associated protein forms regularly arranged filamentous cross-bridges between microtubules. Proc Natl Acad Sci U S A (1999) 1.67
Prospective cognition in animals. Behav Processes (2009) 1.66
Homozygous nonsense mutation in the insulin receptor gene in infant with leprechaunism. Lancet (1993) 1.65
Differentiation of species and strains among filamentous fungi by DNA fingerprinting. Curr Genet (1991) 1.65
The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology (Berl) (2001) 1.64
Systematic assessment of atypical deletions reveals genotype-phenotype correlation in 22q11.2. J Med Genet (2005) 1.62
Towards a functional neuroanatomy of self processing: effects of faces and words. Brain Res Cogn Brain Res (2000) 1.62
Abnormal frontal activations related to decision-making in current and former amphetamine and opiate dependent individuals. Psychopharmacology (Berl) (2005) 1.61
From drugs to deprivation: a Bayesian framework for understanding models of psychosis. Psychopharmacology (Berl) (2009) 1.60
Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas. Cancer Res (2001) 1.60
Phenotypic delineation of ring chromosome 15 and Russell-Silver syndromes. J Med Genet (1985) 1.59
Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17. Hum Mol Genet (1994) 1.58
Molecular signature of CD34(+) hematopoietic stem and progenitor cells of patients with CML in chronic phase. Leukemia (2007) 1.58
Phylogenetics, genome diversity and origin of modern leopard, Panthera pardus. Mol Ecol (2001) 1.58
Evidence for gene-nutrient interaction at the PPARgamma locus. Diabetes (2001) 1.54