Published in Oncol Rep on November 14, 2012
HMGB1 in health and disease. Mol Aspects Med (2014) 1.67
Effect of N-n-butyl haloperidol iodide on ROS/JNK/Egr-1 signaling in H9c2 cells after hypoxia/reoxygenation. Sci Rep (2015) 0.88
Influence of Egr-1 in cardiac tissue-derived mesenchymal stem cells in response to glucose variations. Biomed Res Int (2014) 0.78
Why do cancers have high aerobic glycolysis? Nat Rev Cancer (2004) 20.60
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol (2005) 11.57
Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev (2004) 6.08
Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J Exp Med (2000) 5.90
Necrotic death as a cell fate. Genes Dev (2006) 4.93
Cell death by necrosis: towards a molecular definition. Trends Biochem Sci (2006) 4.67
Inflammation and necrosis promote tumour growth. Nat Rev Immunol (2004) 3.68
Mitochondrial ROS-induced ROS release: an update and review. Biochim Biophys Acta (2006) 3.57
Role of autophagy in cancer: management of metabolic stress. Autophagy (2007) 3.40
Regulation of life and death by the zinc finger transcription factor Egr-1. J Cell Physiol (2002) 3.04
Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail. EMBO J (2006) 2.38
Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation. Biochem J (2009) 2.35
Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism? Ann N Y Acad Sci (2000) 2.25
The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin. Cancer Gene Ther (2006) 2.24
3-D tumor model for in vitro evaluation of anticancer drugs. Mol Pharm (2008) 2.11
Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells. J Biol Chem (2004) 1.94
Angiogenetic signaling through hypoxia: HMGB1: an angiogenetic switch molecule. Am J Pathol (2005) 1.75
Diversity of cell-mediated adhesions in breast cancer spheroids. Int J Oncol (2007) 1.49
Egr1 transcription factor: multiple roles in prostate tumor cell growth and survival. Tumour Biol (2002) 1.48
Early Growth Response-1 gene mediates up-regulation of epidermal growth factor receptor expression during hypoxia. Cancer Res (2002) 1.28
Molecular regulation of the PAI-1 gene by hypoxia: contributions of Egr-1, HIF-1alpha, and C/EBPalpha. FASEB J (2006) 1.24
Wnt/Snail signaling regulates cytochrome C oxidase and glucose metabolism. Cancer Res (2012) 1.19
EGR-1 forms a complex with YAP-1 and upregulates Bax expression in irradiated prostate carcinoma cells. Oncogene (2009) 1.17
Sustained expression of early growth response protein-1 blocks angiogenesis and tumor growth. Cancer Res (2006) 1.17
Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms. Cancer Res (2006) 1.13
Microenvironmental regulation of proliferation in multicellular spheroids is mediated through differential expression of cyclin-dependent kinase inhibitors. Cancer Res (2004) 1.12
Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter. Cancer Res (2007) 1.07
Regulation of radiation-induced apoptosis by early growth response-1 gene in solid tumors. Curr Cancer Drug Targets (2004) 1.00
Egr-1 transactivates Bim gene expression to promote neuronal apoptosis. J Neurosci (2011) 0.99
Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells. Br J Cancer (2010) 0.94
Role of extracellular signal-regulated kinase (ERK)1/2 in multicellular resistance to docetaxel in MCF-7 cells. Int J Oncol (2010) 0.91
Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells. J Cell Physiol (2007) 0.89
Functional activation of the egr-1 (early growth response-1) gene by hydrogen peroxide. Biochem J (1996) 0.89
Homeobox gene Dlx-2 is implicated in metabolic stress-induced necrosis. Mol Cancer (2011) 0.87
Transcriptional regulation of human survivin by early growth response (Egr)-1 transcription factor. Int J Cancer (2008) 0.86
Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulation. Oncogene (2010) 0.85
Implication of snail in metabolic stress-induced necrosis. PLoS One (2011) 0.81
Hyperthermia switches glucose depletion-induced necrosis to apoptosis in A549 lung adenocarcinoma cells. Int J Oncol (2008) 0.80
Janus microspheres for a highly flexible and impregnable water-repelling interface. Angew Chem Int Ed Engl (2010) 2.07
Polymorphism of the DNA repair gene XRCC1 and risk of primary lung cancer. Cancer Epidemiol Biomarkers Prev (2002) 1.28
Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase. J Neurosci (2002) 1.26
Bimetallic anilido-aldimine zinc complexes for epoxide/CO2 copolymerization. J Am Chem Soc (2005) 1.25
Wnt/Snail signaling regulates cytochrome C oxidase and glucose metabolism. Cancer Res (2012) 1.19
Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function. Neoplasia (2009) 1.13
Improved recombinant gene expression in CHO cells using matrix attachment regions. J Biotechnol (2004) 1.07
Polymorphisms of the DNA repair gene xeroderma pigmentosum group A and risk of primary lung cancer. Cancer Epidemiol Biomarkers Prev (2002) 1.07
Tetrandrine-induced cell cycle arrest and apoptosis in A549 human lung carcinoma cells. Int J Oncol (2002) 1.06
Methyl jasmonate induces apoptosis through induction of Bax/Bcl-XS and activation of caspase-3 via ROS production in A549 cells. Oncol Rep (2004) 1.02
Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells. Biomed Pharmacother (2008) 1.01
Histone deacetylase regulates high mobility group A2-targeting microRNAs in human cord blood-derived multipotent stem cell aging. Cell Mol Life Sci (2010) 1.01
Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma. Int J Cancer (2010) 0.99
The protein phosphatase 1/2A inhibitor okadaic acid increases CREB and Elk-1 phosphorylation and c-fos expression in the rat striatum in vivo. J Neurochem (2004) 0.97
Ca2+/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-kappaB activity in LPS-stimulated mouse peritoneal macrophages and RAW 264.7 cells. Biochem Biophys Res Commun (2004) 0.96
Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells. Cancer Lett (2008) 0.96
Induction of apoptosis in human colon cancer HCT-116 cells by anthocyanins through suppression of Akt and activation of p38-MAPK. Int J Oncol (2009) 0.92
Migration of human neural stem cells toward an intracranial glioma. Exp Mol Med (2008) 0.92
Role of extracellular signal-regulated kinase (ERK)1/2 in multicellular resistance to docetaxel in MCF-7 cells. Int J Oncol (2010) 0.91
Sodium salicylate induces apoptosis in HCT116 colorectal cancer cells through activation of p38MAPK. Int J Oncol (2003) 0.91
Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells. J Cell Physiol (2007) 0.89
Anti-invasive activity of diallyl disulfide through tightening of tight junctions and inhibition of matrix metalloproteinase activities in LNCaP prostate cancer cells. Toxicol In Vitro (2010) 0.88
Homeobox gene Dlx-2 is implicated in metabolic stress-induced necrosis. Mol Cancer (2011) 0.87
Lys751Gln polymorphism in the DNA repair gene XPD and risk of primary lung cancer. Lung Cancer (2002) 0.87
Role of reactive oxygen species-dependent protein aggregation in metabolic stress-induced necrosis. Int J Oncol (2010) 0.87
Ethyl pyruvate induces necrosis-to-apoptosis switch and inhibits high mobility group box protein 1 release in A549 lung adenocarcinoma cells. Int J Mol Med (2007) 0.87
Two distinct disulfide bonds formed in human heat shock transcription factor 1 act in opposition to regulate its DNA binding activity. Biochemistry (2008) 0.86
Induction of apoptosis and inhibition of invasion in human hepatoma cells by anthocyanins from meoru. Ann N Y Acad Sci (2009) 0.84
Relationship between XPG codon 1104 polymorphism and risk of primary lung cancer. Carcinogenesis (2003) 0.84
Suppression of human prostate cancer cell growth by beta-lapachone via down-regulation of pRB phosphorylation and induction of Cdk inhibitor p21(WAF1/CIP1). J Biochem Mol Biol (2003) 0.83
Coactivator ASC-2 mediates heat shock factor 1-mediated transactivation dependent on heat shock. FEBS Lett (2004) 0.83
Implication of necrosis-linked p53 aggregation in acquired apoptotic resistance to 5-FU in MCF-7 multicellular tumour spheroids. Oncol Rep (2010) 0.83
Durable plasmonic cap arrays on flexible substrate with real-time optical tunability for high-fidelity SERS devices. ACS Appl Mater Interfaces (2013) 0.83
Anti-invasive activity of anthocyanins isolated from Vitis coignetiae in human hepatocarcinoma cells. J Med Food (2009) 0.82
Induction of heat shock protein 72 in C6 glioma cells by methyl jasmonate through ROS-dependent heat shock factor 1 activation. Int J Mol Med (2005) 0.82
Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation. Int J Oncol (2012) 0.82
Atypical antipsychotic drugs perturb AMPK-dependent regulation of hepatic lipid metabolism. Am J Physiol Endocrinol Metab (2011) 0.82
Microwave-assisted self-organization of colloidal particles in confining aqueous droplets. J Am Chem Soc (2006) 0.81
Implication of snail in metabolic stress-induced necrosis. PLoS One (2011) 0.81
Aromatic-participant interactions are essential for disulfide-bond-based trimerization in human heat shock transcription factor 1. Biochemistry (2009) 0.81
Hypoxia switches glucose depletion-induced necrosis to phosphoinositide 3-kinase/Akt-dependent apoptosis in A549 lung adenocarcinoma cells. Int J Oncol (2010) 0.81
Implication of reactive oxygen species, ERK1/2, and p38MAPK in sodium salicylate-induced heat shock protein 72 expression in C6 glioma cells. Int J Mol Med (2005) 0.81
Hyperthermia switches glucose depletion-induced necrosis to apoptosis in A549 lung adenocarcinoma cells. Int J Oncol (2008) 0.80
Induction of apoptosis in human leukemia U937 cells by anthocyanins through down-regulation of Bcl-2 and activation of caspases. Int J Oncol (2009) 0.80
Perfectly hydrophobic surfaces with patterned nanoneedles of controllable features. Langmuir (2010) 0.80
Integrated analysis of microRNA-target interactions with clinical outcomes for cancers. BMC Med Genomics (2014) 0.80
ATF3 negatively regulates adiponectin receptor 1 expression. Biochem Biophys Res Commun (2010) 0.79
Cloning and characterization of TMPRSS6, a novel type 2 transmembrane serine protease. Mol Cells (2005) 0.79
Porphyromonas gingivalis HSP60 peptides have distinct roles in the development of atherosclerosis. Mol Immunol (2015) 0.79
The hepatoprotective effects of adenine nucleotide translocator-2 against aging and oxidative stress. Free Radic Res (2011) 0.79
The angiogenic effect of probiotic Bacillus polyfermenticus on human intestinal microvascular endothelial cells is mediated by IL-8. Am J Physiol Gastrointest Liver Physiol (2009) 0.79
Anti-invasive activities of anthocyanins through modulation of tight junctions and suppression of matrix metalloproteinase activities in HCT-116 human colon carcinoma cells. Oncol Rep (2010) 0.79
Structure-based virtual screening and biological evaluation of potent and selective ADAM12 inhibitors. Bioorg Med Chem Lett (2004) 0.78
Design and characterisation of doxorubicin-releasing chitosan microspheres for anti-cancer chemoembolisation. J Microencapsul (2012) 0.78
Implication of NAG-1 in synergistic induction of apoptosis by combined treatment of sodium salicylate and PI3K/MEK1/2 inhibitors in A549 human lung adenocarcinoma cells. Biochem Pharmacol (2008) 0.78
[A case of rhabdomyolysis during hospitalization for acute hepatitis A]. Korean J Hepatol (2009) 0.78
Mild heat shock induces cyclin D1 synthesis through multiple Ras signal pathways. FEBS Lett (2002) 0.78
Streptochlorin isolated from Streptomyces sp. Induces apoptosis in human hepatocarcinoma cells through a reactive oxygen species-mediated mitochondrial pathway. J Microbiol Biotechnol (2008) 0.77
Sodium salicylate switches glucose depletion-induced necrosis to autophagy and inhibits high mobility group box protein 1 release in A549 lung adenocarcinoma cells. Oncol Rep (2008) 0.77
Functional HSF1 requires aromatic-participant interactions in protecting mouse embryonic fibroblasts against apoptosis via G2 cell cycle arrest. Mol Cells (2012) 0.77
Rigiflex lithography-based nanodot arrays for localized surface plasmon resonance biosensors. Langmuir (2010) 0.76
3D hierarchical architectures prepared by single exposure through a highly durable colloidal phase mask. Adv Mater (2013) 0.76
Hyperbranched calixarenes: synthesis and applications as fluorescent probes. Chem Commun (Camb) (2009) 0.76
CuZnSOD and MnSOD inhibit metabolic stress-induced necrosis and multicellular tumour spheroid growth. Int J Oncol (2010) 0.76
Implication of PI3K-dependent HSP27 and p53 expression in mild heat shock-triggered switch of metabolic stress-induced necrosis to apoptosis in A549 cells. Int J Oncol (2010) 0.76
A single adenovirus-mediated relaxin delivery attenuates established liver fibrosis in rats. J Gene Med (2016) 0.76