Published in Alcohol on November 28, 2012
Hypothalamic neuropeptide signaling in alcohol addiction. Prog Neuropsychopharmacol Biol Psychiatry (2015) 0.82
Differential role of D1 and D2 receptors in the perifornical lateral hypothalamus in controlling ethanol drinking and food intake: possible interaction with local orexin neurons. Alcohol Clin Exp Res (2013) 0.79
The role of δ-opioid receptors in learning and memory underlying the development of addiction. Br J Pharmacol (2014) 0.79
Hypothalamic peptides controlling alcohol intake: differential effects on microstructure of drinking bouts. Alcohol (2014) 0.77
Delta Opioid Pharmacology in Relation to Alcohol Behaviors. Handb Exp Pharmacol (2016) 0.75
Role of the Dynorphin/Kappa Opioid Receptor System in the Motivational Effects of Ethanol. Alcohol Clin Exp Res (2017) 0.75
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell (1998) 12.66
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci U S A (1998) 9.32
Hedonic hot spot in nucleus accumbens shell: where do mu-opioids cause increased hedonic impact of sweetness? J Neurosci (2005) 3.10
Cloning and sequence analysis of cDNA for porcine beta-neo-endorphin/dynorphin precursor. Nature (1982) 3.09
Anatomy of CNS opioid receptors. Trends Neurosci (1988) 2.82
Opioid modulation of taste hedonics within the ventral striatum. Physiol Behav (2002) 2.62
The role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuse. Psychopharmacology (Berl) (2010) 2.19
The ventral pallidum and hedonic reward: neurochemical maps of sucrose "liking" and food intake. J Neurosci (2005) 2.10
Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal. J Neurosci (2003) 1.89
Lateral hypothalamic orexin/hypocretin neurons: A role in reward-seeking and addiction. Brain Res (2009) 1.79
Isolation and structural organization of the human preproenkephalin gene. Nature (1982) 1.73
Opioids and alcoholism. Physiol Behav (2004) 1.67
Stimuli linked to ethanol availability activate hypothalamic CART and orexin neurons in a reinstatement model of relapse. Biol Psychiatry (2007) 1.67
The lateral hypothalamus as integrator of metabolic and environmental needs: from electrical self-stimulation to opto-genetics. Physiol Behav (2011) 1.47
Intake of saccharin, salt, and ethanol solutions is increased by infusion of a mu opioid agonist into the nucleus accumbens. Psychopharmacology (Berl) (2001) 1.45
Orexigenic peptides and alcohol intake: differential effects of orexin, galanin, and ghrelin. Alcohol Clin Exp Res (2007) 1.42
Potential anxiolytic and antidepressant-like activities of SNC80, a selective delta-opioid agonist, in behavioral models in rodents. J Pharmacol Sci (2004) 1.42
Cocaine-induced reinstatement requires endogenous stimulation of mu-opioid receptors in the ventral pallidum. J Neurosci (2005) 1.41
Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study. Proc Natl Acad Sci U S A (1977) 1.36
Mu opioid receptor and orexin/hypocretin mRNA levels in the lateral hypothalamus and striatum are enhanced by morphine withdrawal. J Endocrinol (2006) 1.34
Increased ethanol self-administration in delta-opioid receptor knockout mice. Alcohol Clin Exp Res (2001) 1.29
Delta opioid receptor ligands modulate anxiety-like behaviors in the rat. Br J Pharmacol (2006) 1.27
Delta-opioid receptor expression in the ventral tegmental area protects against elevated alcohol consumption. J Neurosci (2008) 1.24
Investigation of the effects of opiate antagonists infused into the nucleus accumbens on feeding and sucrose drinking in rats. J Pharmacol Exp Ther (1996) 1.17
The delta(1) opioid receptor is a heterodimer that opposes the actions of the delta(2) receptor on alcohol intake. Biol Psychiatry (2009) 1.17
Differential target-dependent actions of coexpressed inhibitory dynorphin and excitatory hypocretin/orexin neuropeptides. J Neurosci (2006) 1.14
Effect of ethanol on hypothalamic opioid peptides, enkephalin, and dynorphin: relationship with circulating triglycerides. Alcohol Clin Exp Res (2007) 1.09
Sex differences in analgesic, reinforcing, discriminative, and motoric effects of opioids. Exp Clin Psychopharmacol (2008) 1.09
Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement. Psychopharmacology (Berl) (2010) 1.08
Opioids in the hypothalamic paraventricular nucleus stimulate ethanol intake. Alcohol Clin Exp Res (2009) 1.04
Glutamate and GABA in lateral hypothalamic mechanisms controlling food intake. Physiol Behav (2011) 1.01
Differential effects of acute and chronic ethanol exposure on orexin expression in the perifornical lateral hypothalamus. Alcohol Clin Exp Res (2010) 1.01
Mu-opioid receptor-mediated depression of the hypothalamic hypocretin/orexin arousal system. J Neurosci (2008) 1.01
Role of delta-opioid receptor subtypes in anxiety-related behaviors in the elevated plus-maze in rats. Psychopharmacology (Berl) (2005) 0.99
Orexin-A hyperphagia: hindbrain participation in consummatory feeding responses. Endocrinology (2008) 0.95
Methylnaloxonium diffuses out of the rat brain more slowly than naloxone after direct intracerebral injection. Neurosci Lett (1991) 0.93
Involvement of specific orexigenic neuropeptides in sweetener-induced overconsumption in rats. Behav Brain Res (2006) 0.92
Opioids in the nucleus accumbens stimulate ethanol intake. Physiol Behav (2009) 0.90
Endogenous opiates and behavior: 2010. Peptides (2011) 0.88
Ethanol consumption and the matching law: a choice analysis using a limited-access paradigm. Exp Clin Psychopharmacol (2000) 0.88
Similarities in hypothalamic and mesocorticolimbic circuits regulating the overconsumption of food and alcohol. Physiol Behav (2011) 0.88
Effect of opioid receptor ligands injected into the rostral lateral hypothalamus on c-fos and feeding behavior. Brain Res (2006) 0.86
Molecular biology of opioid receptors: recent advances. Neuroimmunomodulation (1998) 0.85
Modulation of feeding and locomotion through mu and delta opioid receptor signaling in the nucleus accumbens. Neuropeptides (2009) 0.84
Decreased intake of sucrose solutions in orexin knockout mice. J Mol Neurosci (2010) 0.84
Opioidergic modulation of ethanol self-administration in the ventral pallidum. Alcohol Clin Exp Res (2011) 0.82
Pharmacokinetics of morphine in striatum and nucleus accumbens: relationship to pharmacological actions. Pharmacol Biochem Behav (1985) 0.81
Self-administration of D-Ala2-Met-enkephalinamide at hypothalamic self-stimulation sites. Brain Res (1980) 0.78
Glutamatergic input to the lateral hypothalamus stimulates ethanol intake: role of orexin and melanin-concentrating hormone. Alcohol Clin Exp Res (2012) 0.78
Differential effects of intrahypothalamic administration of opioids on food intake in naive and tolerant rats. Pharmacol Biochem Behav (1995) 0.77
Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake. Neurosci Biobehav Rev (2007) 5.22
Evidence that intermittent, excessive sugar intake causes endogenous opioid dependence. Obes Res (2002) 2.34
Opiate-like effects of sugar on gene expression in reward areas of the rat brain. Brain Res Mol Brain Res (2004) 2.00
Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity. J Neurosci (2008) 1.96
Hypothalamic huntingtin-associated protein 1 as a mediator of feeding behavior. Nat Med (2006) 1.86
Sugar and fat bingeing have notable differences in addictive-like behavior. J Nutr (2009) 1.77
High-fructose corn syrup causes characteristics of obesity in rats: increased body weight, body fat and triglyceride levels. Pharmacol Biochem Behav (2010) 1.44
Orexigenic peptides and alcohol intake: differential effects of orexin, galanin, and ghrelin. Alcohol Clin Exp Res (2007) 1.42
After daily bingeing on a sucrose solution, food deprivation induces anxiety and accumbens dopamine/acetylcholine imbalance. Physiol Behav (2008) 1.34
Circulating triglycerides impact on orexigenic peptides and neuronal activity in hypothalamus. Endocrinology (2004) 1.31
Sugar-dependent rats show enhanced responding for sugar after abstinence: evidence of a sugar deprivation effect. Physiol Behav (2005) 1.27
Bingeing, self-restriction, and increased body weight in rats with limited access to a sweet-fat diet. Obesity (Silver Spring) (2008) 1.26
Reduced accumbens dopamine in Sprague-Dawley rats prone to overeating a fat-rich diet. Physiol Behav (2010) 1.22
Overlaps in the nosology of substance abuse and overeating: the translational implications of "food addiction". Curr Drug Abuse Rev (2011) 1.14
Amphetamine-sensitized rats show sugar-induced hyperactivity (cross-sensitization) and sugar hyperphagia. Pharmacol Biochem Behav (2003) 1.11
Sugar-dependent rats show enhanced intake of unsweetened ethanol. Alcohol (2005) 1.11
Peptides that regulate food intake: orexin gene expression is increased during states of hypertriglyceridemia. Am J Physiol Regul Integr Comp Physiol (2003) 1.10
Effect of ethanol on hypothalamic opioid peptides, enkephalin, and dynorphin: relationship with circulating triglycerides. Alcohol Clin Exp Res (2007) 1.09
Ethanol intake is increased by injection of galanin in the paraventricular nucleus and reduced by a galanin antagonist. Alcohol (2004) 1.07
Animal models of sugar and fat bingeing: relationship to food addiction and increased body weight. Methods Mol Biol (2012) 1.04
Opioids in the hypothalamic paraventricular nucleus stimulate ethanol intake. Alcohol Clin Exp Res (2009) 1.04
Differential effects of acute and chronic ethanol exposure on orexin expression in the perifornical lateral hypothalamus. Alcohol Clin Exp Res (2010) 1.01
Positive relationship between dietary fat, ethanol intake, triglycerides, and hypothalamic peptides: counteraction by lipid-lowering drugs. Alcohol (2009) 1.00
Galanin microinjection in the third ventricle increases voluntary ethanol intake. Alcohol Clin Exp Res (2004) 1.00
Anterior thalamic paraventricular nucleus is involved in intermittent access ethanol drinking: role of orexin receptor 2. Addict Biol (2014) 0.99
Rats that binge eat fat-rich food do not show somatic signs or anxiety associated with opiate-like withdrawal: implications for nutrient-specific food addiction behaviors. Physiol Behav (2011) 0.99
Ethanol intake increases galanin mRNA in the hypothalamus and withdrawal decreases it. Physiol Behav (2003) 0.98
Complementary roles of orexin and melanin-concentrating hormone in feeding behavior. Int J Endocrinol (2013) 0.97
Elevated D3 dopamine receptor mRNA in dopaminergic and dopaminoceptive regions of the rat brain in response to morphine. Brain Res Mol Brain Res (2003) 0.94
Baclofen suppresses binge eating of pure fat but not a sugar-rich or sweet-fat diet. Behav Pharmacol (2009) 0.93
A high-fat meal or injection of lipids stimulates ethanol intake. Alcohol (2005) 0.92
Effect of chronic ethanol on enkephalin in the hypothalamus and extra-hypothalamic areas. Alcohol Clin Exp Res (2010) 0.91
Galanin knockout mice show disturbances in ethanol consumption and expression of hypothalamic peptides that stimulate ethanol intake. Alcohol Clin Exp Res (2009) 0.91
Sugar bingeing in rats. Curr Protoc Neurosci (2006) 0.90
Opioids in the nucleus accumbens stimulate ethanol intake. Physiol Behav (2009) 0.90
Increased intake of ethanol and dietary fat in galanin overexpressing mice. Alcohol (2009) 0.89
Cholecystokinin combined with serotonin in the hypothalamus limits accumbens dopamine release while increasing acetylcholine: a possible satiation mechanism. Brain Res (2003) 0.89
Regulation of drug and palatable food overconsumption by similar peptide systems. Curr Drug Abuse Rev (2011) 0.88
Similarities in hypothalamic and mesocorticolimbic circuits regulating the overconsumption of food and alcohol. Physiol Behav (2011) 0.88
Pharmacological interventions for binge eating: lessons from animal models, current treatments, and future directions. Curr Pharm Des (2011) 0.88
Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens. Brain Res (2009) 0.87
Developmental changes in embryonic hypothalamic neurons during prenatal fat exposure. Am J Physiol Endocrinol Metab (2012) 0.87
Effects of perinatal exposure to palatable diets on body weight and sensitivity to drugs of abuse in rats. Physiol Behav (2012) 0.87
Inhibition of cocaine self-administration by fluoxetine or D-fenfluramine combined with phentermine. Pharmacol Biochem Behav (2002) 0.85
Galanin and consummatory behavior: special relationship with dietary fat, alcohol and circulating lipids. EXS (2010) 0.84
Activity-based anorexia is associated with reduced hippocampal cell proliferation in adolescent female rats. Behav Brain Res (2012) 0.84
Overlapping peptide control of alcohol self-administration and feeding. Alcohol Clin Exp Res (2004) 0.83
Extracellular glutamate increases in the lateral hypothalamus during meal initiation, and GABA peaks during satiation: microdialysis measurements every 30 s. Behav Neurosci (2003) 0.83
Involvement of cholinergic mechanisms in the behavioral effects of dietary fat consumption. Brain Res (2012) 0.83
Stimulatory role of the chemokine CCL2 in the migration and peptide expression of embryonic hypothalamic neurons. J Neurochem (2014) 0.82
Neurochemical heterogeneity of rats predicted by different measures to be high ethanol consumers. Alcohol Clin Exp Res (2012) 0.82
Fluoxetine alleviates behavioral depression while decreasing acetylcholine release in the nucleus accumbens shell. Neuropsychopharmacology (2011) 0.82
Glucose injection reduces neuropeptide Y and agouti-related protein expression in the arcuate nucleus: a possible physiological role in eating behavior. Brain Res Mol Brain Res (2005) 0.81
Neurobiology of consummatory behavior: mechanisms underlying overeating and drug use. ILAR J (2012) 0.81
Predictors of ethanol consumption in adult Sprague-Dawley rats: relation to hypothalamic peptides that stimulate ethanol intake. Alcohol (2010) 0.81
Increased orexin and melanin-concentrating hormone expression in the perifornical lateral hypothalamus of rats prone to overconsuming a fat-rich diet. Pharmacol Biochem Behav (2010) 0.80
Delayed suppression of hippocampal cell proliferation in rats following inescapable shocks. Brain Res (2006) 0.80
Prenatal exposure to nicotine stimulates neurogenesis of orexigenic peptide-expressing neurons in hypothalamus and amygdala. J Neurosci (2013) 0.80
Effect of dietary fatty acid composition on food intake, triglycerides, and hypothalamic peptides. Regul Pept (2011) 0.79
A high-fat diet prevents and reverses the development of activity-based anorexia in rats. Int J Eat Disord (2008) 0.79
Stimulation of nicotine reward and central cholinergic activity in Sprague-Dawley rats exposed perinatally to a fat-rich diet. Psychopharmacology (Berl) (2013) 0.79
Differential role of D1 and D2 receptors in the perifornical lateral hypothalamus in controlling ethanol drinking and food intake: possible interaction with local orexin neurons. Alcohol Clin Exp Res (2013) 0.79
Cocaine- and amphetamine-regulated transcript in the arcuate nucleus stimulates lipid metabolism to control body fat accrual on a high-fat diet. Regul Pept (2004) 0.79
Acetylcholine in the accumbens is decreased by diazepam and increased by benzodiazepine withdrawal: a possible mechanism for dependency. Eur J Pharmacol (2005) 0.78
Prenatal exposure to dietary fat induces changes in the transcriptional factors, TEF and YAP, which may stimulate differentiation of peptide neurons in rat hypothalamus. PLoS One (2013) 0.78
Glutamatergic input to the lateral hypothalamus stimulates ethanol intake: role of orexin and melanin-concentrating hormone. Alcohol Clin Exp Res (2012) 0.78
GS 455534 selectively suppresses binge eating of palatable food and attenuates dopamine release in the accumbens of sugar-bingeing rats. Behav Pharmacol (2014) 0.77
Disturbances in behavior and cortical enkephalin gene expression during the anticipation of ethanol in rats characterized as high drinkers. Alcohol (2012) 0.77