Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme.

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Published in Nat Commun on January 01, 2012

Authors

Nobuhiko Tokuriki1, Colin J Jackson, Livnat Afriat-Jurnou, Kirsten T Wyganowski, Renmei Tang, Dan S Tawfik

Author Affiliations

1: Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z4. tokuriki@msl.ubc.ca

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