Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (AnTicoagulation and Risk factors In Atrial fibrillation) study cohorts.

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Published in Circulation on December 03, 2012

Authors

Jonathan P Piccini1, Susanna R Stevens, YuChiao Chang, Daniel E Singer, Yuliya Lokhnygina, Alan S Go, Manesh R Patel, Kenneth W Mahaffey, Jonathan L Halperin, Günter Breithardt, Graeme J Hankey, Werner Hacke, Richard C Becker, Christopher C Nessel, Keith A A Fox, Robert M Califf, ROCKET AF Steering Committee and Investigators

Author Affiliations

1: Division of Cardiology, Duke University Medical Center, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27710, USA. jonathan.piccini@duke.edu

Associated clinical trials:

An Efficacy and Safety Study of Rivaroxaban With Warfarin for the Prevention of Stroke and Non-Central Nervous System Systemic Embolism in Patients With Non-Valvular Atrial Fibrillation | NCT00403767

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