| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The COG database: an updated version includes eukaryotes.
|
BMC Bioinformatics
|
2003
|
60.98
|
|
2
|
Evolution and classification of the CRISPR-Cas systems.
|
Nat Rev Microbiol
|
2011
|
17.11
|
|
3
|
A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action.
|
Biol Direct
|
2006
|
11.31
|
|
4
|
Classification and evolution of P-loop GTPases and related ATPases.
|
J Mol Biol
|
2002
|
6.85
|
|
5
|
The ecoresponsive genome of Daphnia pulex.
|
Science
|
2011
|
6.55
|
|
6
|
Essential genes are more evolutionarily conserved than are nonessential genes in bacteria.
|
Genome Res
|
2002
|
6.08
|
|
7
|
Selection in the evolution of gene duplications.
|
Genome Biol
|
2002
|
5.58
|
|
8
|
A comprehensive evolutionary classification of proteins encoded in complete eukaryotic genomes.
|
Genome Biol
|
2004
|
4.94
|
|
9
|
Genomics of bacteria and archaea: the emerging dynamic view of the prokaryotic world.
|
Nucleic Acids Res
|
2008
|
4.78
|
|
10
|
The structure of the protein universe and genome evolution.
|
Nature
|
2002
|
4.47
|
|
11
|
The role of lineage-specific gene family expansion in the evolution of eukaryotes.
|
Genome Res
|
2002
|
4.28
|
|
12
|
Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems.
|
Biol Direct
|
2011
|
3.92
|
|
13
|
Gene loss, protein sequence divergence, gene dispensability, expression level, and interactivity are correlated in eukaryotic evolution.
|
Genome Res
|
2003
|
3.90
|
|
14
|
The complete genome of hyperthermophile Methanopyrus kandleri AV19 and monophyly of archaeal methanogens.
|
Proc Natl Acad Sci U S A
|
2002
|
3.72
|
|
15
|
Remarkable interkingdom conservation of intron positions and massive, lineage-specific intron loss and gain in eukaryotic evolution.
|
Curr Biol
|
2003
|
3.72
|
|
16
|
Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome.
|
Proc Natl Acad Sci U S A
|
2003
|
3.55
|
|
17
|
Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes.
|
Biol Direct
|
2009
|
3.17
|
|
18
|
No simple dependence between protein evolution rate and the number of protein-protein interactions: only the most prolific interactors tend to evolve slowly.
|
BMC Evol Biol
|
2003
|
3.07
|
|
19
|
A universal trend of amino acid gain and loss in protein evolution.
|
Nature
|
2005
|
2.81
|
|
20
|
Conservation and coevolution in the scale-free human gene coexpression network.
|
Mol Biol Evol
|
2004
|
2.78
|
|
21
|
The Big Bang of picorna-like virus evolution antedates the radiation of eukaryotic supergroups.
|
Nat Rev Microbiol
|
2008
|
2.74
|
|
22
|
Search for a 'Tree of Life' in the thicket of the phylogenetic forest.
|
J Biol
|
2009
|
2.66
|
|
23
|
Clusters of orthologous genes for 41 archaeal genomes and implications for evolutionary genomics of archaea.
|
Biol Direct
|
2007
|
2.53
|
|
24
|
Connected gene neighborhoods in prokaryotic genomes.
|
Nucleic Acids Res
|
2002
|
2.35
|
|
25
|
Computational methods for Gene Orthology inference.
|
Brief Bioinform
|
2011
|
2.16
|
|
26
|
Eukaryotic large nucleo-cytoplasmic DNA viruses: clusters of orthologous genes and reconstruction of viral genome evolution.
|
Virol J
|
2009
|
2.13
|
|
27
|
The cyanobacterial genome core and the origin of photosynthesis.
|
Proc Natl Acad Sci U S A
|
2006
|
2.11
|
|
28
|
Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family.
|
J Biol Chem
|
2006
|
2.10
|
|
29
|
Three distinct modes of intron dynamics in the evolution of eukaryotes.
|
Genome Res
|
2007
|
2.06
|
|
30
|
Microevolutionary genomics of bacteria.
|
Theor Popul Biol
|
2002
|
1.95
|
|
31
|
Duplicated genes evolve slower than singletons despite the initial rate increase.
|
BMC Evol Biol
|
2004
|
1.95
|
|
32
|
The deep archaeal roots of eukaryotes.
|
Mol Biol Evol
|
2008
|
1.90
|
|
33
|
Birth and death of protein domains: a simple model of evolution explains power law behavior.
|
BMC Evol Biol
|
2002
|
1.86
|
|
34
|
Phylogenomics of prokaryotic ribosomal proteins.
|
PLoS One
|
2012
|
1.82
|
|
35
|
Comparative genomics of defense systems in archaea and bacteria.
|
Nucleic Acids Res
|
2013
|
1.82
|
|
36
|
Trends in prokaryotic evolution revealed by comparison of closely related bacterial and archaeal genomes.
|
J Bacteriol
|
2008
|
1.79
|
|
37
|
Complete genome sequence of the extremely acidophilic methanotroph isolate V4, Methylacidiphilum infernorum, a representative of the bacterial phylum Verrucomicrobia.
|
Biol Direct
|
2008
|
1.78
|
|
38
|
Ancestral paralogs and pseudoparalogs and their role in the emergence of the eukaryotic cell.
|
Nucleic Acids Res
|
2005
|
1.77
|
|
39
|
Arginyltransferase is an ATP-independent self-regulating enzyme that forms distinct functional complexes in vivo.
|
Chem Biol
|
2011
|
1.76
|
|
40
|
Global analysis of posttranslational protein arginylation.
|
PLoS Biol
|
2007
|
1.75
|
|
41
|
Insights into archaeal evolution and symbiosis from the genomes of a nanoarchaeon and its inferred crenarchaeal host from Obsidian Pool, Yellowstone National Park.
|
Biol Direct
|
2013
|
1.75
|
|
42
|
Purifying and directional selection in overlapping prokaryotic genes.
|
Trends Genet
|
2002
|
1.74
|
|
43
|
Evolutionary systems biology: links between gene evolution and function.
|
Curr Opin Biotechnol
|
2006
|
1.68
|
|
44
|
A low-polynomial algorithm for assembling clusters of orthologous groups from intergenomic symmetric best matches.
|
Bioinformatics
|
2010
|
1.67
|
|
45
|
Is evolution Darwinian or/and Lamarckian?
|
Biol Direct
|
2009
|
1.67
|
|
46
|
Comparative genomics of Thermus thermophilus and Deinococcus radiodurans: divergent routes of adaptation to thermophily and radiation resistance.
|
BMC Evol Biol
|
2005
|
1.63
|
|
47
|
Genome sequence of the deep-sea gamma-proteobacterium Idiomarina loihiensis reveals amino acid fermentation as a source of carbon and energy.
|
Proc Natl Acad Sci U S A
|
2004
|
1.62
|
|
48
|
Evolution of mosaic operons by horizontal gene transfer and gene displacement in situ.
|
Genome Biol
|
2003
|
1.62
|
|
49
|
Evolution of gene fusions: horizontal transfer versus independent events.
|
Genome Biol
|
2002
|
1.60
|
|
50
|
Genomic determinants of sporulation in Bacilli and Clostridia: towards the minimal set of sporulation-specific genes.
|
Environ Microbiol
|
2012
|
1.59
|
|
51
|
Genome-wide molecular clock and horizontal gene transfer in bacterial evolution.
|
J Bacteriol
|
2004
|
1.58
|
|
52
|
Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements.
|
Biol Direct
|
2009
|
1.58
|
|
53
|
The tree and net components of prokaryote evolution.
|
Genome Biol Evol
|
2010
|
1.55
|
|
54
|
Congruent evolution of different classes of non-coding DNA in prokaryotic genomes.
|
Nucleic Acids Res
|
2002
|
1.54
|
|
55
|
Potential genomic determinants of hyperthermophily.
|
Trends Genet
|
2003
|
1.54
|
|
56
|
Defense islands in bacterial and archaeal genomes and prediction of novel defense systems.
|
J Bacteriol
|
2011
|
1.53
|
|
57
|
Deinococcus geothermalis: the pool of extreme radiation resistance genes shrinks.
|
PLoS One
|
2007
|
1.52
|
|
58
|
The origins of phagocytosis and eukaryogenesis.
|
Biol Direct
|
2009
|
1.49
|
|
59
|
Patterns of intron gain and conservation in eukaryotic genes.
|
BMC Evol Biol
|
2007
|
1.42
|
|
60
|
Constraints and plasticity in genome and molecular-phenome evolution.
|
Nat Rev Genet
|
2010
|
1.41
|
|
61
|
Encapsulated in silica: genome, proteome and physiology of the thermophilic bacterium Anoxybacillus flavithermus WK1.
|
Genome Biol
|
2008
|
1.39
|
|
62
|
Non-homologous isofunctional enzymes: a systematic analysis of alternative solutions in enzyme evolution.
|
Biol Direct
|
2010
|
1.35
|
|
63
|
Identification of novel positive-strand RNA viruses by metagenomic analysis of archaea-dominated Yellowstone hot springs.
|
J Virol
|
2012
|
1.33
|
|
64
|
Universal pacemaker of genome evolution.
|
PLoS Comput Biol
|
2012
|
1.31
|
|
65
|
ATGC: a database of orthologous genes from closely related prokaryotic genomes and a research platform for microevolution of prokaryotes.
|
Nucleic Acids Res
|
2008
|
1.30
|
|
66
|
A tight link between orthologs and bidirectional best hits in bacterial and archaeal genomes.
|
Genome Biol Evol
|
2012
|
1.25
|
|
67
|
Evolutionarily conserved genes preferentially accumulate introns.
|
Genome Res
|
2007
|
1.25
|
|
68
|
The basic building blocks and evolution of CRISPR-CAS systems.
|
Biochem Soc Trans
|
2013
|
1.23
|
|
69
|
Evolutionary primacy of sodium bioenergetics.
|
Biol Direct
|
2008
|
1.23
|
|
70
|
Genomes in turmoil: quantification of genome dynamics in prokaryote supergenomes.
|
BMC Biol
|
2014
|
1.21
|
|
71
|
Small proteins can no longer be ignored.
|
Annu Rev Biochem
|
2014
|
1.21
|
|
72
|
Universal distribution of protein evolution rates as a consequence of protein folding physics.
|
Proc Natl Acad Sci U S A
|
2010
|
1.20
|
|
73
|
Ecdysozoan clade rejected by genome-wide analysis of rare amino acid replacements.
|
Mol Biol Evol
|
2007
|
1.19
|
|
74
|
Viral diversity threshold for adaptive immunity in prokaryotes.
|
MBio
|
2012
|
1.17
|
|
75
|
Computational approaches for the analysis of gene neighbourhoods in prokaryotic genomes.
|
Brief Bioinform
|
2004
|
1.16
|
|
76
|
Comparable contributions of structural-functional constraints and expression level to the rate of protein sequence evolution.
|
Biol Direct
|
2008
|
1.15
|
|
77
|
Predictability of evolutionary trajectories in fitness landscapes.
|
PLoS Comput Biol
|
2011
|
1.12
|
|
78
|
Evolution of microbes and viruses: a paradigm shift in evolutionary biology?
|
Front Cell Infect Microbiol
|
2012
|
1.11
|
|
79
|
The fundamental units, processes and patterns of evolution, and the tree of life conundrum.
|
Biol Direct
|
2009
|
1.09
|
|
80
|
Nature and intensity of selection pressure on CRISPR-associated genes.
|
J Bacteriol
|
2011
|
1.08
|
|
81
|
Differential translation tunes uneven production of operon-encoded proteins.
|
Cell Rep
|
2013
|
1.06
|
|
82
|
Evolutionary plasticity of protein families: coupling between sequence and structure variation.
|
Proteins
|
2005
|
1.06
|
|
83
|
Evolutionary dynamics of N-glycosylation sites of influenza virus hemagglutinin.
|
PLoS Curr
|
2009
|
1.06
|
|
84
|
Analysis of rare amino acid replacements supports the Coelomata clade.
|
Mol Biol Evol
|
2007
|
1.06
|
|
85
|
Seeing the Tree of Life behind the phylogenetic forest.
|
BMC Biol
|
2013
|
1.04
|
|
86
|
Simple stochastic birth and death models of genome evolution: was there enough time for us to evolve?
|
Bioinformatics
|
2003
|
1.02
|
|
87
|
Role of hypermutability in the evolution of the genus Oenococcus.
|
J Bacteriol
|
2007
|
0.99
|
|
88
|
Gene family evolution: an in-depth theoretical and simulation analysis of non-linear birth-death-innovation models.
|
BMC Evol Biol
|
2004
|
0.99
|
|
89
|
An insertion in the catalytic trigger loop gates the secondary channel of RNA polymerase.
|
J Mol Biol
|
2012
|
0.98
|
|
90
|
Comparison of phylogenetic trees and search for a central trend in the "forest of life".
|
J Comput Biol
|
2011
|
0.98
|
|
91
|
Evolution of the genetic code: partial optimization of a random code for robustness to translation error in a rugged fitness landscape.
|
Biol Direct
|
2007
|
0.96
|
|
92
|
Gene frequency distributions reject a neutral model of genome evolution.
|
Genome Biol Evol
|
2013
|
0.94
|
|
93
|
Drastic neofunctionalization associated with evolution of the timezyme AANAT 500 Mya.
|
Proc Natl Acad Sci U S A
|
2013
|
0.92
|
|
94
|
Dark matter in archaeal genomes: a rich source of novel mobile elements, defense systems and secretory complexes.
|
Extremophiles
|
2014
|
0.92
|
|
95
|
The common ancestry of life.
|
Biol Direct
|
2010
|
0.92
|
|
96
|
The vast, conserved mammalian lincRNome.
|
PLoS Comput Biol
|
2013
|
0.91
|
|
97
|
Evolutionary dynamics of the prokaryotic adaptive immunity system CRISPR-Cas in an explicit ecological context.
|
J Bacteriol
|
2013
|
0.89
|
|
98
|
Estimation of prokaryotic supergenome size and composition from gene frequency distributions.
|
BMC Genomics
|
2014
|
0.82
|
|
99
|
Genome-wide comparative analysis of phylogenetic trees: the prokaryotic forest of life.
|
Methods Mol Biol
|
2012
|
0.81
|
|
100
|
EREM: Parameter Estimation and Ancestral Reconstruction by Expectation-Maximization Algorithm for a Probabilistic Model of Genomic Binary Characters Evolution.
|
Adv Bioinformatics
|
2010
|
0.81
|
|
101
|
A maximum likelihood method for reconstruction of the evolution of eukaryotic gene structure.
|
Methods Mol Biol
|
2009
|
0.79
|
|
102
|
Evolution of the CRISPR-Cas adaptive immunity systems in prokaryotes: models and observations on virus-host coevolution.
|
Mol Biosyst
|
2014
|
0.79
|
|
103
|
Virus-host arms race at the joint origin of multicellularity and programmed cell death.
|
Cell Cycle
|
2014
|
0.78
|
|
104
|
Quantifying the similarity of monotonic trajectories in rough and smooth fitness landscapes.
|
Mol Biosyst
|
2013
|
0.77
|
|
105
|
Reply to "codon usage frequency of RNA virus genomes from high-temperature acidic-environment metagenomes".
|
J Virol
|
2013
|
0.77
|
|
106
|
Pseudo-chaotic oscillations in CRISPR-virus coevolution predicted by bifurcation analysis.
|
Biol Direct
|
2014
|
0.75
|
|
107
|
Microbial genome analysis: the COG approach.
|
Brief Bioinform
|
2017
|
0.75
|