Published in Epigenomics on December 01, 2012
Lead exposure disrupts global DNA methylation in human embryonic stem cells and alters their neuronal differentiation. Toxicol Sci (2014) 0.94
Environmental alterations of epigenetics prior to the birth. Int Rev Neurobiol (2014) 0.85
Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities. ALTEX (2014) 0.82
Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood. Epigenetics (2015) 0.81
Evolutionary development of embryonic cerebrospinal fluid composition and regulation: an open research field with implications for brain development and function. Fluids Barriers CNS (2016) 0.75
Lead poisoning mimicking acute porphyria! J Clin Diagn Res (2014) 0.75
Original Research: The expression of MMP2 and MMP9 in the hippocampus and cerebral cortex of newborn mice under maternal lead exposure. Exp Biol Med (Maywood) (2016) 0.75
Lead Poisoning Can Be Easily Misdiagnosed as Acute Porphyria and Nonspecific Abdominal Pain. Case Rep Emerg Med (2017) 0.75
Birth defects in infants born to employees of a microelectronics and business machine manufacturing facility. Birth Defects Res A Clin Mol Teratol (2016) 0.75
Epigenetics, obesity and early-life cadmium or lead exposure. Epigenomics (2016) 0.75
Sex- and Brain Region- Specific Effects of Prenatal Stress and Lead Exposure on Permissive and Repressive Post-Translational Histone Modifications from Embryonic Development Through Adulthood. Neurotoxicology (2017) 0.75
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (2009) 32.97
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell (1992) 27.80
Epigenetic programming by maternal behavior. Nat Neurosci (2004) 20.92
Intellectual impairment in children with blood lead concentrations below 10 microg per deciliter. N Engl J Med (2003) 16.73
Non-coding RNAs in human disease. Nat Rev Genet (2011) 11.40
Low-level environmental lead exposure and children's intellectual function: an international pooled analysis. Environ Health Perspect (2005) 10.66
In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol (2001) 9.04
Regulation of chromatin by histone modifications. Cell Res (2011) 8.44
Induction of human neuronal cells by defined transcription factors. Nature (2011) 6.84
The fetal and infant origins of adult disease. BMJ (1990) 6.38
Epigenetic regulation in psychiatric disorders. Nat Rev Neurosci (2007) 6.00
Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science (1999) 4.69
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat Neurosci (2011) 4.15
Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc Natl Acad Sci U S A (2004) 3.60
Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children. Environ Health Perspect (2006) 3.56
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proc Natl Acad Sci U S A (2012) 3.52
Gender differences in the disposition and toxicity of metals. Environ Res (2006) 2.91
Reframing sexual differentiation of the brain. Nat Neurosci (2011) 2.49
Lead. Pediatrics (2004) 2.38
Neuropsychological function in children with blood lead levels <10 microg/dL. Neurotoxicology (2007) 2.31
Histone methylation regulates memory formation. J Neurosci (2010) 2.30
Histone deacetylase activity is necessary for oligodendrocyte lineage progression. J Neurosci (2002) 2.00
Environmental chemical exposures and human epigenetics. Int J Epidemiol (2011) 1.97
MicroRNAs in neuronal function and dysfunction. Trends Neurosci (2012) 1.94
Epigenetic control of neural precursor cell fate during development. Nat Rev Neurosci (2010) 1.93
Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD. J Neurosci (2008) 1.92
Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal. Mol Psychiatry (2004) 1.92
Association of prenatal and childhood blood lead concentrations with criminal arrests in early adulthood. PLoS Med (2008) 1.88
Low-level human equivalent gestational lead exposure produces sex-specific motor and coordination abnormalities and late-onset obesity in year-old mice. Environ Health Perspect (2008) 1.84
Decreased brain volume in adults with childhood lead exposure. PLoS Med (2008) 1.84
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DNA methylation and its basic function. Neuropsychopharmacology (2012) 1.76
Influence of prenatal lead exposure on genomic methylation of cord blood DNA. Environ Health Perspect (2009) 1.74
New and evolving concepts in the neurotoxicology of lead. Toxicol Appl Pharmacol (2007) 1.74
Neurotoxic effects and biomarkers of lead exposure: a review. Rev Environ Health (2009) 1.74
Transgenerational epigenetic inheritance: more questions than answers. Genome Res (2010) 1.67
Epigenetic regulation of neural gene expression and neuronal function. Pediatr Res (2007) 1.59
Biomarkers of lead exposure and DNA methylation within retrotransposons. Environ Health Perspect (2010) 1.58
Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases. Hum Mol Genet (2010) 1.54
Co-exposure to environmental lead and manganese affects the intelligence of school-aged children. Neurotoxicology (2009) 1.50
The fetal basis of amyloidogenesis: exposure to lead and latent overexpression of amyloid precursor protein and beta-amyloid in the aging brain. J Neurosci (2005) 1.46
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Confirmation and extension of association of blood lead with attention-deficit/hyperactivity disorder (ADHD) and ADHD symptom domains at population-typical exposure levels. J Child Psychol Psychiatry (2009) 1.38
Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis, LTP and spatial memory. Nat Neurosci (2011) 1.37
The protean toxicities of lead: new chapters in a familiar story. Int J Environ Res Public Health (2011) 1.29
Environmental lead exposure during early life alters granule cell neurogenesis and morphology in the hippocampus of young adult rats. Neuroscience (2007) 1.27
Teratogen update: lead and pregnancy. Birth Defects Res A Clin Mol Teratol (2005) 1.22
Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress. Epigenetics (2011) 1.22
DNA methylation changes in whole blood is associated with exposure to the environmental contaminants, mercury, lead, cadmium and bisphenol A, in women undergoing ovarian stimulation for IVF. Hum Reprod (2012) 1.16
Chromosome silencing mechanisms in X-chromosome inactivation: unknown unknowns. Development (2011) 1.10
Crosstalk among Epigenetic Pathways Regulates Neurogenesis. Front Neurosci (2012) 1.10
Altered myelination and axonal integrity in adults with childhood lead exposure: a diffusion tensor imaging study. Neurotoxicology (2009) 1.09
Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing. Cell Death Differ (2010) 1.09
Environmental epigenetics in metal exposure. Epigenetics (2011) 1.08
Neurotoxicity in young adults 20 years after childhood exposure to lead: the Bunker Hill experience. Occup Environ Med (1998) 1.06
Infant exposure to lead (Pb) and epigenetic modifications in the aging primate brain: implications for Alzheimer's disease. J Alzheimers Dis (2011) 1.06
The impact of early childhood lead exposure on brain organization: a functional magnetic resonance imaging study of language function. Pediatrics (2006) 1.04
Genome-wide expression and methylation profiling in the aged rodent brain due to early-life Pb exposure and its relevance to aging. Mech Ageing Dev (2012) 1.03
Epigenetic targets of some toxicologically relevant metals: a review of the literature. J Appl Toxicol (2012) 1.02
Enhanced learning deficits in female rats following lifetime pb exposure combined with prenatal stress. Toxicol Sci (2010) 1.00
Gender specific differences in neurodevelopmental effects of prenatal exposure to very low-lead levels: the prospective cohort study in three-year olds. Early Hum Dev (2009) 1.00
Lead poisoning in a historical perspective. Am J Ind Med (2000) 0.96
Molecular neurobiology of lead (Pb(2+)): effects on synaptic function. Mol Neurobiol (2010) 0.94
Epigenetic assessment of environmental chemicals detected in maternal peripheral and cord blood samples. J Reprod Dev (2011) 0.94
Effects of developmental lead exposure on the hippocampal transcriptome: influences of sex, developmental period, and lead exposure level. Toxicol Sci (2012) 0.89
Sex-based differences in gene expression in hippocampus following postnatal lead exposure. Toxicol Appl Pharmacol (2011) 0.89
Dysregulation of BDNF-TrkB signaling in developing hippocampal neurons by Pb(2+): implications for an environmental basis of neurodevelopmental disorders. Toxicol Sci (2012) 0.88
Lead dysregulates serine/threonine protein phosphatases in human neurons. Neurochem Res (2010) 0.86
Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses. Neurotoxicology (2011) 0.86
Epigenetic mechanisms in metal toxicity. Toxicol Mech Methods (2011) 0.85
Prenatal lead levels, plasma amyloid β levels, and gene expression in young adulthood. Environ Health Perspect (2012) 0.85
Genetic variation in the epigenetic machinery and mental health. Curr Psychiatry Rep (2012) 0.83
Chronic lead exposure alters presynaptic calcium regulation and synaptic facilitation in Drosophila larvae. Neurotoxicology (2009) 0.82
p16 promoter methylation in Pb2+ -exposed individuals. Clin Toxicol (Phila) (2010) 0.82
Protective effect of 17-beta-estradiol in human neurocellular models of lead exposure. Neurotoxicology (2006) 0.82
Effects of maternal lead exposure on functional plasticity in the visual cortex and hippocampus of immature rats. Brain Res Dev Brain Res (1994) 0.79
Panel advises tougher limits on lead exposure. JAMA (2012) 0.79
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet (2009) 6.02
Genome-wide analysis of cancer/testis gene expression. Proc Natl Acad Sci U S A (2008) 2.66
A survey of small RNAs in human sperm. Hum Reprod (2011) 1.62
Mice and men: their promoter properties. PLoS Genet (2006) 1.50
CloudAligner: A fast and full-featured MapReduce based tool for sequence mapping. BMC Res Notes (2011) 1.05
Generation of leukemia inhibitory factor and basic fibroblast growth factor-dependent induced pluripotent stem cells from canine adult somatic cells. Stem Cells Dev (2011) 1.03
CaM kinase II-dependent phosphorylation of myogenin contributes to activity-dependent suppression of nAChR gene expression in developing rat myotubes. Cell Signal (2004) 1.00
Lead exposure disrupts global DNA methylation in human embryonic stem cells and alters their neuronal differentiation. Toxicol Sci (2014) 0.94
Caudalized human iPSC-derived neural progenitor cells produce neurons and glia but fail to restore function in an early chronic spinal cord injury model. Exp Neurol (2013) 0.93
Genome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1. PLoS Pathog (2013) 0.84
An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria. PLoS One (2012) 0.83
Gene expression profiling of replicative and induced senescence. Cell Cycle (2014) 0.82
Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood. Epigenetics (2015) 0.81
Introduction to serial reviews on EpRE and its signaling pathway. Free Radic Biol Med (2004) 0.79
Genetic aspects of behavioral neurotoxicology. Neurotoxicology (2009) 0.79
Conservation of avian germplasm by xenogeneic transplantation of spermatogonia from sexually mature donors. Stem Cells Dev (2012) 0.77
Positional mapping and candidate gene analysis of the mouse Ccs3 locus that regulates differential susceptibility to carcinogen-induced colorectal cancer. PLoS One (2013) 0.76
Defining the diversity of phenotypic respecification using multiple cell lines and reprogramming regimens. Stem Cells Dev (2013) 0.76
Effects of donor fibroblasts expressing OCT4 on bovine embryos generated by somatic cell nuclear transfer. Cell Reprogram (2012) 0.76
Activity-dependent gene regulation in conditionally-immortalized muscle precursor cell lines. J Cell Biochem (2004) 0.76