Published in IUBMB Life on January 01, 2013
Uncovering the overlapping community structure of complex networks in nature and society. Nature (2005) 13.05
Mechanism of blebbistatin inhibition of myosin II. J Biol Chem (2004) 5.45
CFinder: locating cliques and overlapping modules in biological networks. Bioinformatics (2006) 4.27
Myosin cleft movement and its coupling to actomyosin dissociation. Nat Struct Biol (2003) 1.80
Coalescence of membrane tethers: experiments, theory, and applications. Biophys J (2005) 1.66
Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments. J Immunol (2003) 1.43
Force barriers for membrane tube formation. Phys Rev Lett (2005) 1.42
Dynamic response of adhesion complexes: beyond the single-path picture. Phys Rev E Stat Nonlin Soft Matter Phys (2002) 1.41
The mechanism of the reverse recovery step, phosphate release, and actin activation of Dictyostelium myosin II. J Biol Chem (2008) 1.37
Reversible movement of switch 1 loop of myosin determines actin interaction. EMBO J (2007) 1.17
Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme. J Biol Chem (2007) 1.14
Crystal structure reveals basis for the inhibitor resistance of human brain trypsin. J Mol Biol (2002) 1.14
Dynamics of actomyosin interactions in relation to the cross-bridge cycle. Philos Trans R Soc Lond B Biol Sci (2004) 1.08
Congruent evolution of genetic and environmental robustness in micro-RNA. Mol Biol Evol (2009) 1.07
Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r. Mol Immunol (2007) 1.05
A novel actin binding site of myosin required for effective muscle contraction. Nat Struct Mol Biol (2012) 1.00
Unconventional translation initiation of human trypsinogen 4 at a CUG codon with an N-terminal leucine. A possible means to regulate gene expression. FEBS J (2007) 0.99
Differential actin binding along the PEVK domain of skeletal muscle titin. J Cell Sci (2004) 0.98
The effect of F-actin on the relay helix position of myosin II, as revealed by tryptophan fluorescence, and its implications for mechanochemical coupling. Biochemistry (2004) 0.94
Drug effect prediction by polypharmacology-based interaction profiling. J Chem Inf Model (2011) 0.92
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke. Proc Natl Acad Sci U S A (2010) 0.91
Cleavage site analysis of a serralysin-like protease, PrtA, from an insect pathogen Photorhabdus luminescens and development of a highly sensitive and specific substrate. FEBS J (2007) 0.91
Myelin basic protein, an autoantigen in multiple sclerosis, is selectively processed by human trypsin 4. FEBS Lett (2005) 0.91
Nucleotide pocket thermodynamics measured by EPR reveal how energy partitioning relates myosin speed to efficiency. J Mol Biol (2010) 0.90
Probing conformational plasticity of the activation domain of trypsin: the role of glycine hinges. Biochemistry (2008) 0.89
Reverse engineering of linking preferences from network restructuring. Phys Rev E Stat Nonlin Soft Matter Phys (2004) 0.89
Comparison of proteolytic activities produced by entomopathogenic Photorhabdus bacteria: strain- and phase-dependent heterogeneity in composition and activity of four enzymes. Appl Environ Microbiol (2004) 0.89
When the surface tells what lies beneath: combinatorial phage-display mutagenesis reveals complex networks of surface-core interactions in the pacifastin protease inhibitor family. J Mol Biol (2007) 0.88
Engineering Dictyostelium discoideum myosin II for the introduction of site-specific fluorescence probes. J Muscle Res Cell Motil (2002) 0.88
Extended intermolecular interactions in a serine protease-canonical inhibitor complex account for strong and highly specific inhibition. J Mol Biol (2005) 0.88
Enzyme:substrate hydrogen bond shortening during the acylation phase of serine protease catalysis. Biochemistry (2006) 0.88
Human serum fetuin A/alpha2HS-glycoprotein level is associated with long-term survival in patients with alcoholic liver cirrhosis, comparison with the Child-Pugh and MELD scores. BMC Gastroenterol (2007) 0.88
Regional distribution of human trypsinogen 4 in human brain at mRNA and protein level. Neurochem Res (2007) 0.88
para-Nitroblebbistatin, the non-cytotoxic and photostable myosin II inhibitor. Angew Chem Int Ed Engl (2014) 0.88
Same fold with different mobility: backbone dynamics of small protease inhibitors from the desert locust, Schistocerca gregaria. Biochemistry (2004) 0.87
Reversible heat-induced dissociation of β2-microglobulin amyloid fibrils. Biochemistry (2011) 0.87
The effect of recombination on the neutral evolution of genetic robustness. Math Biosci (2008) 0.85
Experimental investigation of the seesaw mechanism of the relay region that moves the myosin lever arm. J Biol Chem (2008) 0.85
Comparative structure analysis of proteinase inhibitors from the desert locust, Schistocerca gregaria. Eur J Biochem (2002) 0.85
Serum fetuin-A in metabolic and inflammatory pathways in patients with myocardial infarction. Eur J Clin Invest (2011) 0.84
Mechanism of lysophosphatidic acid-induced amyloid fibril formation of beta(2)-microglobulin in vitro under physiological conditions. Biochemistry (2009) 0.84
Breaking the hierarchy--a new cluster selection mechanism for hierarchical clustering methods. Algorithms Mol Biol (2009) 0.84
Remarkable phylum selectivity of a Schistocerca gregaria trypsin inhibitor: the possible role of enzyme-inhibitor flexibility. Arch Biochem Biophys (2002) 0.84
The maintenance of sex in bacteria is ensured by its potential to reload genes. Genetics (2006) 0.84
Streamlined determination of processive run length and mechanochemical coupling of nucleic acid motor activities. Nucleic Acids Res (2010) 0.84
Ala226 to Gly and Ser189 to Asp mutations convert rat chymotrypsin B to a trypsin-like protease. Protein Eng Des Sel (2004) 0.84
Kinetic characterization of the function of myosin loop 4 in the actin-myosin interaction. Biochemistry (2007) 0.83
Combining EPR with fluorescence spectroscopy to monitor conformational changes at the myosin nucleotide pocket. J Mol Biol (2009) 0.83
Enzymic characterization with progress curve analysis of a collagen peptidase from an enthomopathogenic bacterium, Photorhabdus luminescens. Biochem J (2004) 0.82
Three dimensional structures of S189D chymotrypsin and D189S trypsin mutants: the effect of polarity at site 189 on a protease-specific stabilization of the substrate-binding site. J Mol Biol (2003) 0.82
Resonance energy transfer between green fluorescent protein variants: complexities revealed with myosin fusion proteins. Biochemistry (2006) 0.82
The crystal structure of a trypsin-like mutant chymotrypsin: the role of position 226 in the activity and specificity of S189D chymotrypsin. Protein J (2008) 0.80
Relating the shape of protein binding sites to binding affinity profiles: is there an association? BMC Struct Biol (2010) 0.80
Virtual affinity fingerprints for target fishing: a new application of Drug Profile Matching. J Chem Inf Model (2012) 0.80
The catalytic aspartate is protonated in the Michaelis complex formed between trypsin and an in vitro evolved substrate-like inhibitor: a refined mechanism of serine protease action. J Biol Chem (2010) 0.79
Thermodynamic analysis reveals structural rearrangement during the acylation step in human trypsin 4 on 4-methylumbelliferyl 4-guanidinobenzoate substrate analogue. J Biol Chem (2006) 0.79
Azidoblebbistatin, a photoreactive myosin inhibitor. Proc Natl Acad Sci U S A (2012) 0.79
Isolation, biochemical characterization, and molecular modeling of American lobster digestive cathepsin D1. Comp Biochem Physiol B Biochem Mol Biol (2010) 0.78
Experimental confirmation of new drug-target interactions predicted by Drug Profile Matching. J Med Chem (2013) 0.78
Characterization of a trypsin-like serine protease of activated B cells mediating the cleavage of surface proteins. Biochim Biophys Acta (2003) 0.78
Statistical mechanics of topological phase transitions in networks. Phys Rev E Stat Nonlin Soft Matter Phys (2004) 0.78
Contribution of 2D and 3D structural features of drug molecules in the prediction of Drug Profile Matching. J Chem Inf Model (2012) 0.78
Temperature dependence of internal friction in enzyme reactions. FASEB J (2011) 0.78
Human trypsin(ogen) 4-like immunoreactivity in the white matter of the cerebral cortex and the spinal cord. Ideggyogy Sz (2007) 0.78
Neck-linker docking coordinates the kinetics of kinesin's heads. Biophys J (2011) 0.78
Biochemical characterization of Acacia schweinfurthii serine proteinase inhibitor. J Enzyme Inhib Med Chem (2013) 0.77
Local binding with globally distributed changes in a small protease inhibitor upon enzyme binding. FEBS J (2006) 0.77
Characterization of f-actin tryptophan phosphorescence in the presence and absence of tryptophan-free myosin motor domain. Biophys J (2004) 0.76
The relevance of neck linker docking in the motility of kinesin. Biosystems (2008) 0.76
Inhibition of Colorado potato beetle larvae by a locust proteinase inhibitor peptide expressed in potato. Biotechnol Lett (2005) 0.76
Cloning and expression of ostrich trypsinogen: an avian trypsin with a highly sensitive autolysis site. Biochim Biophys Acta (2005) 0.76
Comparison of complexes formed by a crustacean and a vertebrate trypsin with bovine pancreatic trypsin inhibitor - the key to achieving extreme stability? FEBS J (2013) 0.76
Evolutionary games on minimally structured populations. Phys Rev E Stat Nonlin Soft Matter Phys (2008) 0.76
Identification of PPARγ ligands with One-dimensional Drug Profile Matching. Drug Des Devel Ther (2013) 0.75
Enzyme kinetics above denaturation temperature: a temperature-jump/stopped-flow apparatus. Biophys J (2006) 0.75
Engineering lysine reactivity as a conformational sensor in the Dictyostelium myosin II motor domain. J Muscle Res Cell Motil (2004) 0.75
[Churg-Strauss syndrome complicated by polyneuropathy]. Orv Hetil (2006) 0.75
Development of hat-shaped liposomes on solid supports. Langmuir (2014) 0.75
Anoxia leads to a rapid translocation of human trypsinogen 4 to the plasma membrane of cultured astrocytes. J Neurochem (2010) 0.75
Mutant rat trypsin selectively cleaves tyrosyl peptide bonds. Anal Biochem (2004) 0.75
Site directed mutagenesis at position 193 of human trypsin 4 alters the rate of conformational change during activation: role of local internal viscosity in protein dynamics. Proteins (2007) 0.75
Directed self-assembly of lipid nanotubes from inverted hexagonal structures. ACS Nano (2012) 0.75
Emergence of large-scale vorticity during diffusion in a random potential under an alternating bias. Phys Rev E Stat Nonlin Soft Matter Phys (2005) 0.75