The evolutionary role of the IL-33/ST2 system in host immune defence.

PubWeight™: 0.94‹?›

🔗 View Article (PMID 23283516)

Published in Arch Immunol Ther Exp (Warsz) on January 03, 2013

Authors

Susanne Sattler1, Hermelijn H Smits, Damo Xu, Fang-Ping Huang

Author Affiliations

1: Department of Medicine, Centre for Complement and Inflammation Research, Imperial College London, Hammersmith Campus, Du Cane Road, W12 0NN London, UK. s.sattler@imperial.ac.uk

Articles by these authors

Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol (2005) 9.70

Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells. Proc Natl Acad Sci U S A (2006) 3.70

IL-33 reduces the development of atherosclerosis. J Exp Med (2008) 3.59

IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation. J Immunol (2009) 3.41

IL-33, a potent inducer of adaptive immunity to intestinal nematodes. J Immunol (2008) 3.31

ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat Immunol (2004) 3.19

TLR2 is expressed on activated T cells as a costimulatory receptor. Proc Natl Acad Sci U S A (2004) 3.04

IL-33 induces antigen-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4. J Immunol (2008) 2.83

IL-33 is a chemoattractant for human Th2 cells. Eur J Immunol (2007) 2.43

Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection. Nat Med (2010) 2.38

Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses. J Exp Med (2009) 2.24

CD4+CD25+ regulatory T cells cure murine colitis: the role of IL-10, TGF-beta, and CTLA4. J Immunol (2003) 2.19

Retracted The cytokine interleukin-33 mediates anaphylactic shock. Proc Natl Acad Sci U S A (2009) 2.15

Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN. J Exp Med (2004) 2.08

Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circ Res (2010) 1.80

IL-33 exacerbates eosinophil-mediated airway inflammation. J Immunol (2010) 1.73

Dendritic cell-mediated T cell polarization. Springer Semin Immunopathol (2004) 1.72

IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice. Proc Natl Acad Sci U S A (2008) 1.67

IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Ann Rheum Dis (2010) 1.62

A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. J Immunol (2004) 1.55

Regulatory T cells in human geohelminth infection suppress immune responses to BCG and Plasmodium falciparum. Eur J Immunol (2010) 1.45

IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages. Eur J Immunol (2012) 1.43

T1/ST2--an IL-1 receptor-like modulator of immune responses. Cytokine Growth Factor Rev (2004) 1.43

TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T cells. J Immunol (2005) 1.41

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor. J Exp Med (2012) 1.32

Galectin-3 is a negative regulator of lipopolysaccharide-mediated inflammation. J Immunol (2008) 1.29

Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis. J Immunol (2009) 1.28

IL28B genetic variation is associated with spontaneous clearance of hepatitis C virus, treatment response, serum IL-28B levels in Chinese population. PLoS One (2012) 1.25

Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages. J Immunol (2002) 1.23

Regulatory B-cell induction by helminths: implications for allergic disease. J Allergy Clin Immunol (2011) 1.17

Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells. PLoS One (2012) 1.15

Sustained IL-12 signaling is required for Th1 development. J Immunol (2004) 1.15

TLR1/TLR2 agonist induces tumor regression by reciprocal modulation of effector and regulatory T cells. J Immunol (2011) 1.13

Systemic autoimmune disease induced by dendritic cells that have captured necrotic but not apoptotic cells in susceptible mouse strains. Eur J Immunol (2005) 1.12

Serum levels of IL-33 and soluble ST2 and their association with disease activity in systemic lupus erythematosus. Rheumatology (Oxford) (2009) 1.11

Helminths and dendritic cells: sensing and regulating via pattern recognition receptors, Th2 and Treg responses. Eur J Immunol (2010) 1.08

Glucocorticoid-induced TNFR family-related protein (GITR) activation exacerbates murine asthma and collagen-induced arthritis. Eur J Immunol (2005) 1.08

Regulatory T cells in human lymphatic filariasis: stronger functional activity in microfilaremics. PLoS Negl Trop Dis (2012) 1.07

Interleukin-33 exacerbates acute colitis via interleukin-4 in mice. Immunology (2013) 1.07

ST2, an IL-1R family member, attenuates inflammation and lethality after intestinal ischemia and reperfusion. J Leukoc Biol (2006) 1.03

T-helper 17 cells are associated with pathology in human schistosomiasis. J Infect Dis (2012) 1.02

IL-33 activates B1 cells and exacerbates contact sensitivity. J Immunol (2011) 1.01

Host genetic background determines whether IL-18 deficiency results in increased susceptibility or resistance to murine Leishmania major infection. Immunol Lett (2004) 0.98

Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function. Ann Rheum Dis (2011) 0.98

Functional impairment of human myeloid dendritic cells during Schistosoma haematobium infection. PLoS Negl Trop Dis (2010) 0.97

Monocyte-derived dendritic cells exposed to Der p 1 allergen enhance the recruitment of Th2 cells: major involvement of the chemokines TARC/CCL17 and MDC/CCL22. Eur Cytokine Netw (2004) 0.97

ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: increased ICOS expression enhances the effector function of both Th1 and Th2 cells. J Immunol (2004) 0.95

Chemoattraction of human T cells by IL-18. J Immunol (2003) 0.95

A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration. Blood (2009) 0.95

Direct recognition of LPS by human but not murine CD8+ T cells via TLR4 complex. Eur J Immunol (2009) 0.94

Enhancing the antihepatitis B virus immune response by adefovir dipivoxil and entecavir therapies. Cell Mol Immunol (2010) 0.94

A novel negative regulator for IL-1 receptor and Toll-like receptor 4. Immunol Lett (2005) 0.92

Asymptomatic plasmodial infection is associated with increased tumor necrosis factor receptor II-expressing regulatory T cells and suppressed type 2 immune responses. J Infect Dis (2013) 0.92

A novel subset of putative stem/progenitor CD34+Oct-4+ cells is the major target for SARS coronavirus in human lung. J Exp Med (2007) 0.91

Administration of exogenous interleukin-18 and interleukin-12 prevents the induction of oral tolerance. Immunology (2003) 0.89

Specific glycan elements determine differential binding of individual egg glycoproteins of the human parasite Schistosoma mansoni by host C-type lectin receptors. Int J Parasitol (2012) 0.89

An essential protective role of IL-10 in the immunological mechanism underlying resistance vs. susceptibility to lupus induction by dendritic cells and dying cells. Rheumatology (Oxford) (2011) 0.89

CD26/DPPIV signal transduction function, but not proteolytic activity, is directly related to its expression level on human Th1 and Th2 cell lines as detected with living cell cytochemistry. J Histochem Cytochem (2002) 0.88

Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: roles of IL-2 versus IL-15. Eur J Immunol (2008) 0.88

A crucial role for dendritic cell (DC) IL-10 in inhibiting successful DC-based immunotherapy: superior antitumor immunity against hepatocellular carcinoma evoked by DC devoid of IL-10. J Immunol (2007) 0.86

Anti-interleukin-33 inhibits cigarette smoke-induced lung inflammation in mice. Immunology (2013) 0.86

Attenuated bacteria as effectors in cancer immunotherapy. Ann N Y Acad Sci (2008) 0.84

TLR9-independent effects of inhibitory oligonucleotides on macrophage responses to S. typhimurium. Immunol Cell Biol (2008) 0.83

Alterations in peripheral blood B cell subsets and dynamics of B cell responses during human schistosomiasis. PLoS Negl Trop Dis (2013) 0.82

The mucosal adjuvant cholera toxin B instructs non-mucosal dendritic cells to promote IgA production via retinoic acid and TGF-β. PLoS One (2013) 0.82

Differential responses of cord and adult blood-derived dendritic cells to dying cells. Immunology (2005) 0.82

Toll-like receptor ligation for the induction of regulatory B cells. Methods Mol Biol (2014) 0.80

Rapamycin and omega-1: mTOR-dependent and -independent Th2 skewing by human dendritic cells. Immunol Cell Biol (2013) 0.80

Association of ICAM3 genetic variant with severe acute respiratory syndrome. J Infect Dis (2007) 0.79

Anti-Toll-like receptor 2 and 4 antibodies suppress inflammatory response in mice. Immunology (2014) 0.79

Antiviral treatment alters the frequency of activating and inhibitory receptor-expressing natural killer cells in chronic hepatitis B virus infected patients. Mediators Inflamm (2012) 0.78

Potential of immunoglobulin A to prevent allergic asthma. Clin Dev Immunol (2013) 0.78

Uptake of antigens from the intestine by dendritic cells. Ann N Y Acad Sci (2004) 0.77

A novel function for dendritic cell: clearance of VEGF via VEGF receptor-1. Biochem Biophys Res Commun (2009) 0.77

Activation of innate immune responses by IL-2-expressing Salmonella typhimurium is independent of Toll-like receptor 4. Mol Immunol (2004) 0.76

Antiviral treatment improves disrupted peripheral B lymphocyte homeostasis in chronic hepatitis B virus-infected patients. Exp Biol Med (Maywood) (2013) 0.76

Innate, adaptive and regulatory responses in schistosomiasis: relationship to allergy. Chem Immunol Allergy (2006) 0.76

Retraction. The cytokine interleukin-33 mediates anaphylactic shock. Proc Natl Acad Sci U S A (2012) 0.75

A highly optimized protocol for reprogramming cancer cells to pluripotency using nonviral plasmid vectors. Cell Reprogram (2014) 0.75

Microorganism-induced suppression of allergic airway disease: novel therapies on the horizon? Expert Rev Respir Med (2014) 0.75

Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2. Res Sq (2020) 0.75