Systemic autoimmune disease induced by dendritic cells that have captured necrotic but not apoptotic cells in susceptible mouse strains.

PubWeight™: 1.12‹?› | Rank: Top 10%

🔗 View Article (PMID 16224814)

Published in Eur J Immunol on November 01, 2005

Authors

Liang Ma1, Kwok-Wah Chan, Nigel J Trendell-Smith, Adrian Wu, Lina Tian, Audrey C Lam, Albert K Chan, Chi-Kin Lo, Stanley Chik, King-Hung Ko, Christina K W To, Siu-Kee Kam, Xiao-Song Li, Cui-Hong Yang, Suet Yi Leung, Mun-Hon Ng, David I Stott, G Gordon MacPherson, Fang-Ping Huang

Author Affiliations

1: Department of Pathology, University of Hong Kong, Hong Kong, China.

Articles citing this

Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells. Nature (2016) 2.43

Regulation of lupus-related autoantibody production and clinical disease by Toll-like receptors. Semin Immunol (2007) 1.69

Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation. J Immunol (2009) 1.52

Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis. J Immunol (2009) 1.39

Oxidative stress in the pathology and treatment of systemic lupus erythematosus. Nat Rev Rheumatol (2013) 1.27

Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins. J Immunol (2009) 1.21

The role of dendritic cells in the pathogenesis of systemic lupus erythematosus. Arthritis Res Ther (2010) 1.04

IL-10-producing regulatory B cells induced by IL-33 (Breg(IL-33)) effectively attenuate mucosal inflammatory responses in the gut. J Autoimmun (2014) 1.03

Apoptotic cell death and lupus. Springer Semin Immunopathol (2006) 1.02

Duration of chronic inflammation alters gene expression in muscle from untreated girls with juvenile dermatomyositis. BMC Immunol (2008) 1.01

Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus. J Immunol (2013) 0.99

Nitric oxide, mitochondrial hyperpolarization, and T cell activation. Free Radic Biol Med (2007) 0.94

T-cell and B-cell signaling biomarkers and treatment targets in lupus. Curr Opin Rheumatol (2009) 0.94

Systems biology of lupus: mapping the impact of genomic and environmental factors on gene expression signatures, cellular signaling, metabolic pathways, hormonal and cytokine imbalance, and selecting targets for treatment. Autoimmunity (2010) 0.92

Role of interleukin-10 and interleukin-10 receptor in systemic lupus erythematosus. Clin Rheumatol (2013) 0.92

An essential protective role of IL-10 in the immunological mechanism underlying resistance vs. susceptibility to lupus induction by dendritic cells and dying cells. Rheumatology (Oxford) (2011) 0.89

Maturation of dendritic cells by necrotic thyrocytes facilitates induction of experimental autoimmune thyroiditis. Clin Exp Immunol (2006) 0.88

The receptor tyrosine kinase MerTK regulates dendritic cell production of BAFF. Autoimmunity (2009) 0.87

Toll-like receptor 7 (TLR7) modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells. Ann Rheum Dis (2009) 0.85

Metabolic regulation of organelle homeostasis in lupus T cells. Clin Immunol (2012) 0.81

Targeting dendritic cell function during systemic autoimmunity to restore tolerance. Int J Mol Sci (2014) 0.80

Contribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosus. Immunology (2015) 0.79

Impact of loss of NF-κB1, NF-κB2 or c-REL on SLE-like autoimmune disease and lymphadenopathy in Fas(lpr/lpr) mutant mice. Immunol Cell Biol (2015) 0.77

Autocrine IFNγ controls the regulatory function of lymphoproliferative double negative T cells. PLoS One (2012) 0.76

Radical innate regulation of autoimmune diabetes. Free Radic Biol Med (2012) 0.75

Articles by these authors

Patterns of somatic mutation in human cancer genomes. Nature (2007) 38.41

MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA (2008) 12.26

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer. Nat Genet (2009) 10.21

Efficacy and safety of a recombinant hepatitis E vaccine in healthy adults: a large-scale, randomised, double-blind placebo-controlled, phase 3 trial. Lancet (2010) 7.11

Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial. JAMA (2004) 6.96

Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology (2007) 5.75

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer. Nat Genet (2011) 5.68

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1. Nat Genet (2008) 4.44

Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer. Nat Genet (2006) 3.89

Recurrent KRAS codon 146 mutations in human colorectal cancer. Cancer Biol Ther (2006) 3.56

Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors. Proc Natl Acad Sci U S A (2007) 3.20

Long-term efficacy of a hepatitis E vaccine. N Engl J Med (2015) 3.00

Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus. Proc Natl Acad Sci U S A (2008) 2.33

Leptin exacerbates collagen-induced arthritis via enhancement of Th17 cell response. Arthritis Rheum (2012) 2.26

Mutations of PIK3CA in gastric adenocarcinoma. BMC Cancer (2005) 2.06

Seroprevalence of hepatitis E virus infection, rural southern People's Republic of China. Emerg Infect Dis (2006) 1.84

Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus. Arthritis Rheum (2003) 1.84

Relationships between distinct blood monocyte subsets and migrating intestinal lymph dendritic cells in vivo under steady-state conditions. J Immunol (2006) 1.79

Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer. Mol Biol Cell (2007) 1.69

Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma. Clin Cancer Res (2009) 1.67

Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma. Clin Cancer Res (2008) 1.64

Prions and their lethal journey to the brain. Nat Rev Microbiol (2006) 1.60

Differential effects of immunosuppressive drugs on chemokine receptor CCR7 in human monocyte-derived dendritic cells: selective upregulation by rapamycin. Transplantation (2006) 1.58

Migrating intestinal dendritic cells transport PrP(Sc) from the gut. J Gen Virol (2002) 1.58

Novel function of B cell-activating factor in the induction of IL-10-producing regulatory B cells. J Immunol (2010) 1.57

Hyporesponsiveness of intestinal dendritic cells to TLR stimulation is limited to TLR4. J Immunol (2009) 1.50

Increased adiposity at diagnosis in younger children with type 1 diabetes does not persist. Diabetes Care (2006) 1.40

Indian hedgehog regulates intestinal stem cell fate through epithelial-mesenchymal interactions during development. Gastroenterology (2010) 1.38

Upregulation of Twist in oesophageal squamous cell carcinoma is associated with neoplastic transformation and distant metastasis. J Clin Pathol (2006) 1.36

Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles. Oncogene (2004) 1.30

Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours. Carcinogenesis (2005) 1.30

Prevalence of hepatitis E virus in Chinese blood donors. J Clin Microbiol (2009) 1.29

Performance of detecting IgM antibodies against enterovirus 71 for early diagnosis. PLoS One (2010) 1.28

Kidney claudin-19: localization in distal tubules and collecting ducts and dysregulation in polycystic renal disease. FEBS Lett (2006) 1.27

Do all prepubertal years of diabetes duration contribute equally to diabetes complications? Diabetes Care (2003) 1.27

Putative receptor-binding sites of hepatitis E virus. J Gen Virol (2008) 1.26

Mutational analysis of essential interactions involved in the assembly of hepatitis E virus capsid. J Biol Chem (2004) 1.24

Diverse proteomic alterations in gastric adenocarcinoma. Proteomics (2004) 1.24

A gene expression signature of genetic instability in colon cancer. Cancer Res (2005) 1.23

Antigen-driven clonal proliferation, somatic hypermutation, and selection of B lymphocytes infiltrating human ductal breast carcinomas. Cancer Res (2003) 1.22

Topological and functional discovery in a gene coexpression meta-network of gastric cancer. Cancer Res (2006) 1.22

Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. Gastroenterology (2006) 1.20

Germline, somatic and epigenetic events underlying mismatch repair deficiency in colorectal and HNPCC-related cancers. Oncogene (2002) 1.18

Randomized-controlled phase II clinical trial of a bacterially expressed recombinant hepatitis E vaccine. Vaccine (2009) 1.16

DJ-1 could predict worse prognosis in esophageal squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev (2008) 1.13

Comprehensive analysis of the gene expression profiles in human gastric cancer cell lines. Oncogene (2002) 1.11

Vitamin D deficiency is associated with retinopathy in children and adolescents with type 1 diabetes. Diabetes Care (2011) 1.10

Regulation of intestinal dendritic cell migration and activation by plasmacytoid dendritic cells, TNF-alpha and type 1 IFNs after feeding a TLR7/8 ligand. J Immunol (2006) 1.09

Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma. Oncogene (2003) 1.09

IL-10-producing regulatory B10 cells ameliorate collagen-induced arthritis via suppressing Th17 cell generation. Am J Pathol (2012) 1.09

Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer. PLoS One (2012) 1.08

Natural history and risk factors for microalbuminuria in adolescents with type 1 diabetes: a longitudinal study. Diabetes Care (2006) 1.07

Profile of acute infectious markers in sporadic hepatitis E. PLoS One (2010) 1.04

A distinct subset of intestinal dendritic cells responds selectively to oral TLR7/8 stimulation. Eur J Immunol (2006) 1.03

Hepatitis E vaccine development: a 14 year odyssey. Hum Vaccin Immunother (2012) 1.02

Neurolymphomatosis: role of positron emission tomography in diagnosis. Ann Hematol (2011) 1.02

EFA6A enhances glioma cell invasion through ADP ribosylation factor 6/extracellular signal-regulated kinase signaling. Cancer Res (2006) 1.01

Suppression of androgen-independent prostate cancer cell aggressiveness by FTY720: validating Runx2 as a potential antimetastatic drug screening platform. Clin Cancer Res (2009) 1.00

Blue-shifted lithium bonds. Chem Commun (Camb) (2003) 0.99

Id proteins expression in prostate cancer: high-level expression of Id-4 in primary prostate cancer is associated with development of metastases. Mod Pathol (2006) 0.99

Rat bone marrow-derived dendritic cells, but not ex vivo dendritic cells, secrete nitric oxide and can inhibit T-cell proliferation. Immunology (2003) 0.98

Polyomavirus enhancer activator 3 protein promotes breast cancer metastatic progression through Snail-induced epithelial-mesenchymal transition. J Pathol (2011) 0.98

TWIST modulates prostate cancer cell-mediated bone cell activity and is upregulated by osteogenic induction. Carcinogenesis (2008) 0.97

Leptin signaling protects NK cells from apoptosis during development in mouse bone marrow. Cell Mol Immunol (2009) 0.97

Altered E-cadherin expression and p120 catenin localization in esophageal squamous cell carcinoma. Ann Surg Oncol (2007) 0.97

A critical role of IL-17 in modulating the B-cell response during H5N1 influenza virus infection. Cell Mol Immunol (2011) 0.97

Quantifying tumour-infiltrating lymphocyte subsets: a practical immuno-histochemical method. J Immunol Methods (2007) 0.97

Mutations of BRAF and KRAS in gastric cancer and their association with microsatellite instability. Int J Cancer (2004) 0.96

Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms. Gastroenterology (2009) 0.96

MSH2 c.1452-1455delAATG is a founder mutation and an important cause of hereditary nonpolyposis colorectal cancer in the southern Chinese population. Am J Hum Genet (2004) 0.96

Identification of hepatitis A virus mimotopes by phage display, antigenicity and immunogenicity. J Virol Methods (2006) 0.95

Prophylactic and therapeutic effects of small interfering RNA targeting SARS-coronavirus. Antivir Ther (2004) 0.95

Generalized propensity score for estimating the average treatment effect of multiple treatments. Stat Med (2011) 0.95

Membrane type 1-matrix metalloproteinase is involved in the migration of human monocyte-derived dendritic cells. Immunol Cell Biol (2006) 0.95

CDC25A functions as a novel Ar corepressor in prostate cancer cells. J Mol Biol (2008) 0.94

The evolutionary role of the IL-33/ST2 system in host immune defence. Arch Immunol Ther Exp (Warsz) (2013) 0.94

A novel Dirofilaria species causing human and canine infections in Hong Kong. J Clin Microbiol (2012) 0.93

Glucocorticoid-induced tumor necrosis factor receptor family-related protein exacerbates collagen-induced arthritis by enhancing the expansion of Th17 cells. Am J Pathol (2011) 0.93

The role of autoimmunity at diagnosis of type 1 diabetes in the development of thyroid and celiac disease and microvascular complications. Diabetes Care (2005) 0.93

Expression and function of TNF family member B cell-activating factor in the development of autoimmune arthritis. Int Immunol (2005) 0.92

Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells. Biosci Rep (2012) 0.92

Plasmacytoid dendritic cells do not migrate in intestinal or hepatic lymph. J Immunol (2006) 0.91

Hepatitis E virus: neutralizing sites, diagnosis, and protective immunity. Rev Med Virol (2012) 0.91

Mycobacterium abscessus bacteremia after receipt of intravenous infusate of cytokine-induced killer cell therapy for body beautification and health boosting. Clin Infect Dis (2013) 0.91

Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer. Chin J Dig Dis (2006) 0.91

A novel subset of putative stem/progenitor CD34+Oct-4+ cells is the major target for SARS coronavirus in human lung. J Exp Med (2007) 0.91

Association between PON 1 polymorphisms, PON activity and diabetes complications. J Diabetes Complications (2006) 0.91

How do DCs interact with intestinal antigens? Trends Immunol (2005) 0.90

Impaired V(D)J recombination and increased apoptosis among B cell precursors in the bone marrow of c-Abl-deficient mice. Int Immunol (2007) 0.90

Natural killer cell degeneration exacerbates experimental arthritis in mice via enhanced interleukin-17 production. Arthritis Rheum (2008) 0.89

An essential protective role of IL-10 in the immunological mechanism underlying resistance vs. susceptibility to lupus induction by dendritic cells and dying cells. Rheumatology (Oxford) (2011) 0.89

The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus. Arthritis Res Ther (2003) 0.88

Bioluminescence of Aequorea macrodactyla, a common jellyfish species in the East China Sea. Mar Biotechnol (NY) (2002) 0.88

Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: roles of IL-2 versus IL-15. Eur J Immunol (2008) 0.88

Expression of HSPA2 in human hepatocellular carcinoma and its clinical significance. Tumour Biol (2014) 0.87

V(H) replacement in rearranged immunoglobulin genes. Immunology (2005) 0.87