Published in Oxid Med Cell Longev on December 25, 2012
Impaired resolution of inflammation in the Endoglin heterozygous mouse model of chronic colitis. Mediators Inflamm (2014) 0.83
Contribution of oxidative stress to endothelial dysfunction in hereditary hemorrhagic telangiectasia. Front Genet (2015) 0.80
Impaired wound repair in adult endoglin heterozygous mice associated with lower NO bioavailability. J Invest Dermatol (2013) 0.79
Acarbose Accelerates Wound Healing via Akt/eNOS Signaling in db/db Mice. Oxid Med Cell Longev (2017) 0.75
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Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells. Blood (2006) 3.59
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Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia. N Engl J Med (2001) 3.29
Measurement of reactive oxygen species in cardiovascular studies. Hypertension (2007) 3.17
A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 (SMAD4). Lancet (2004) 2.97
Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. J Biol Chem (1999) 2.77
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Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension. Hum Mutat (2006) 2.30
Reactive oxygen species in cardiovascular disease. Free Radic Biol Med (2011) 2.29
NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology. Antioxid Redox Signal (2009) 2.29
Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling. Circ Res (2003) 1.87
Oxidative stress in severe pulmonary hypertension. Am J Respir Crit Care Med (2003) 1.85
Hereditary hemorrhagic telangiectasia: an overview of diagnosis, management, and pathogenesis. Genet Med (2011) 1.81
A new locus for hereditary haemorrhagic telangiectasia (HHT3) maps to chromosome 5. J Med Genet (2005) 1.78
A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia. Circ Res (2005) 1.76
Genotype-phenotype relationship in hereditary haemorrhagic telangiectasia. J Med Genet (2005) 1.76
Comparative pharmacology of chemically distinct NADPH oxidase inhibitors. Br J Pharmacol (2010) 1.67
Pulmonary hypertension in adult Alk1 heterozygous mice due to oxidative stress. Cardiovasc Res (2011) 1.59
Clinical outcomes of pulmonary arterial hypertension in patients carrying an ACVRL1 (ALK1) mutation. Am J Respir Crit Care Med (2010) 1.50
Endoglin regulates nitric oxide-dependent vasodilatation. FASEB J (2004) 1.47
A fourth locus for hereditary hemorrhagic telangiectasia maps to chromosome 7. Am J Med Genet A (2006) 1.46
A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2. Hum Mol Genet (2003) 1.38
Hereditary haemorrhagic telangiectasia: a questionnaire based study to delineate the different phenotypes caused by endoglin and ALK1 mutations. J Med Genet (2003) 1.28
Targeting NADPH oxidases in vascular pharmacology. Vascul Pharmacol (2012) 1.20
Reactive oxygen species and endothelial function--role of nitric oxide synthase uncoupling and Nox family nicotinamide adenine dinucleotide phosphate oxidases. Basic Clin Pharmacol Toxicol (2011) 1.18
Expression analysis of four endoglin missense mutations suggests that haploinsufficiency is the predominant mechanism for hereditary hemorrhagic telangiectasia type 1. Hum Mol Genet (1999) 1.13
Caveolin-1 interacts and cooperates with the transforming growth factor-beta type I receptor ALK1 in endothelial caveolae. Cardiovasc Res (2007) 1.07
Pathogenetic role of eNOS uncoupling in cardiopulmonary disorders. Free Radic Biol Med (2010) 1.06
Increased lipid peroxidation in patients with pulmonary hypertension. Am J Respir Crit Care Med (2001) 1.05
Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species. Arterioscler Thromb Vasc Biol (2010) 1.04
Functional analysis of the BMP9 response of ALK1 mutants from HHT2 patients: a diagnostic tool for novel ACVRL1 mutations. Blood (2010) 1.04
Mitochondria and vascular pathology. Pharmacol Rep (2009) 0.97
Spontaneous adult-onset pulmonary arterial hypertension attributable to increased endothelial oxidative stress in a murine model of hereditary hemorrhagic telangiectasia. Arterioscler Thromb Vasc Biol (2009) 0.95
Regulatory role of mitochondria in oxidative stress and atherosclerosis. World J Cardiol (2010) 0.94
Mechanotransduction of stretch-induced prostanoid release by fetal lung epithelial cells. Am J Physiol Lung Cell Mol Physiol (2006) 0.93
The effect of N-acetylcysteine on epistaxis and quality of life in patients with HHT: a pilot study. Rhinology (2009) 0.92
Age-dependent endothelial nitric oxide synthase uncoupling in pulmonary arteries of endoglin heterozygous mice. Am J Physiol Lung Cell Mol Physiol (2009) 0.91
Direct, real-time monitoring of superoxide generation in isolated mitochondria. Free Radic Res (2009) 0.91
Early-life pulmonary arterial hypertension with subsequent development of diffuse pulmonary arteriovenous malformations in hereditary haemorrhagic telangiectasia type 1. Thorax (2008) 0.88
Reduction of myocardial infarct size by tetrahydrobiopterin: possible involvement of mitochondrial KATP channels activation through nitric oxide production. J Cardiovasc Pharmacol (2006) 0.84
Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med (2006) 6.21
Reduced angiogenic responses in adult Endoglin heterozygous mice. Cardiovasc Res (2006) 1.88
A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia. Circ Res (2005) 1.76
Pulmonary hypertension in adult Alk1 heterozygous mice due to oxidative stress. Cardiovasc Res (2011) 1.59
Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta1 with higher affinity receptors and an activated Alk1 pathway. J Biol Chem (2005) 1.47
Cerebral vascular abnormalities in a murine model of hereditary hemorrhagic telangiectasia. Stroke (2003) 1.25
VE-cadherin is a critical endothelial regulator of TGF-beta signalling. EMBO J (2008) 1.22
Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure. Circulation (2012) 1.12
Multivalent recombinant proteins for probing functions of leucocyte surface proteins such as the CD200 receptor. Immunology (2005) 1.10
Novel mutations and polymorphisms in genes causing hereditary hemorrhagic telangiectasia. Hum Mutat (2005) 1.07
Endoglin upregulation during experimental renal interstitial fibrosis in mice. Hypertension (2002) 1.04
Disease-associated mutations in conserved residues of ALK-1 kinase domain. Eur J Hum Genet (2003) 1.02
Soluble endoglin modulates aberrant cerebral vascular remodeling. Ann Neurol (2009) 0.98
Spontaneous adult-onset pulmonary arterial hypertension attributable to increased endothelial oxidative stress in a murine model of hereditary hemorrhagic telangiectasia. Arterioscler Thromb Vasc Biol (2009) 0.95
Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis. Oncogene (2003) 0.95
Characterization of 17 novel endoglin mutations associated with hereditary hemorrhagic telangiectasia. Hum Mutat (2003) 0.95
A critical role for endoglin in the emergence of blood during embryonic development. Blood (2012) 0.95
Characterization of murine S-endoglin isoform and its effects on tumor development. Oncogene (2005) 0.93
Endoglin regulates cyclooxygenase-2 expression and activity. Circ Res (2006) 0.93
Symptomatic children with hereditary hemorrhagic telangiectasia: a pediatric center experience. Arch Pediatr Adolesc Med (2006) 0.87
Dextran sulfate sodium leads to chronic colitis and pathological angiogenesis in Endoglin heterozygous mice. Inflamm Bowel Dis (2010) 0.87
Anti-VEGF therapy reduces intestinal inflammation in Endoglin heterozygous mice subjected to experimental colitis. Angiogenesis (2014) 0.85
Androgen modulation of adhesion and antiadhesion molecules in PC-3 prostate cancer cells expressing androgen receptor. Endocrinology (2002) 0.85
Functional role of CD105 in TGF-beta1 signalling in murine and human endothelial cells. Anticancer Res (2005) 0.83
Endoglin and activin receptor-like kinase 1 heterozygous mice have a distinct pulmonary and hepatic angiogenic profile and response to anti-VEGF treatment. Angiogenesis (2013) 0.82
Cost comparison of genetic and clinical screening in families with hereditary hemorrhagic telangiectasia. Am J Med Genet A (2005) 0.82
Endoglin: a critical mediator of cardiovascular health. Vasc Health Risk Manag (2013) 0.81
TGF-{beta} signaling of human T cells is modulated by the ancillary TGF-{beta} receptor endoglin. Int Immunol (2005) 0.80
Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo. Dev Biol (2009) 0.80
Loss of coordinated androgen regulation in nonmalignant ovarian epithelial cells with BRCA1/2 mutations and ovarian cancer cells. Cancer Res (2003) 0.80
Rho-kinase inhibitor prevents bleomycin-induced injury in neonatal rats independent of effects on lung inflammation. Am J Respir Cell Mol Biol (2014) 0.79
Novel protein interactions with endoglin and activin receptor-like kinase 1: potential role in vascular networks. Mol Cell Proteomics (2013) 0.77
Symptomatic liver involvement in neonatal hereditary hemorrhagic telangiectasia. Pediatrics (2011) 0.77